*2.5. Manuscript Selections*

Two independent reviewers of two different universities (Messina and Naples) singularly analyzed the obtained papers in order to select inclusion and exclusion criteria as follows. Reviewers correlated their evaluations and analyzed differences through comparing the manuscripts and consulting a third experienced senor independent reviewer (Loma Linda University) when consensus could not be reached. For the stage of the full-text articles revision, a complete independent dual analysis was performed.
