*4.8. Statistical Analyses*

Statistical analysis was performed using one-way ANOVA plus Tukey's post-test (GraphPad Software, Inc., San Diego, CA, USA). *p* values < 0.05 were considered to be significant.

**Acknowledgments:** The authors are indebted to Laura Negretti and Mauro Michetti for their precious technical support in ESEM analyses. This work was supported by University of Genova Funding to both S.S. and M.G. and to SIR funding by the Italian Ministry of University and Research (MIUR) to M.B.

**Author Contributions:** M.P.: conception and design of the work, manuscript writing, experimental design, data analysis and interpretation. S.S.: conception of the work and experimental design, manuscript writing, data analysis and interpretation, financial support. L.G., M.C., S.V., K.C. and M.C.G.: experimental design and data analysis. M.B. and G.C.: collection of specimens. M.G.: critical review of the manuscript and financial support.

**Conflicts of Interest:** The authors declare no conflict of interest.
