*2.1. Patients*

Between January 2016 and December 2019, pediatric patients aged 6 months–18 years affected by IgE-mediated milk and/or egg allergy were consecutively evaluated for their reactivity to baked milk/egg at Allergy Division of Bambino Gesù Children's Hospital in Rome. Patients with a history of immediate (<2 h) reactions to baked milk and/or egg sensitized to baked milk and/or egg using skin prick test (SPT) and with a positive specific IgE determination for milk, egg and/or their fractions, were included. For those without a recent convincing history of anaphylaxis, a confirmatory OFC with baked milk and/or egg was required. Children with unstable asthma and severe uncontrolled eczema were included when clinically stabilized.
