*2.2. Study Design*

In a monocentric, prospective design, the patients were exposed to double-blind, placebo-controlled food challenge (DBPCFC) with milk-free, egg-containing or egg-free, milk-containing biscuits for confirmation of baked egg or baked milk allergy, respectively. The usual contraindications to OFCs were applied [14]: when an anaphylactic reaction had occurred <6 months before inclusion into the study for children of 0.5 to 5 years; <12 months for children aged 6–12 years, and <2 years for adolescents, the clinical history

was considered sufficient proof of allergy to baked milk or egg. Such patients were not exposed to any confirmatory DBPCFC.

Children allergic to baked proteins were tested for their tolerance to egg-free, milk-free biscuits at OFC and SPT.
