*2.1. Pru p 1*

Pru p 1 is a member of the PR-10 protein family and is present in the pulp and the skin of peach [14]. It shares a structural homology with the major birch pollen, Bet v1 [15]. For this reason, Pru p1 sensitization is commonly found in Northern and Central Europe, where the exposure to birch pollen is high and usually results in oral allergy syndrome (OAS) symptoms [15]. Pru p1 cross-reacts with other PR-10 protein families, such as *Rosaceae* fruits, hazelnut, carrots, and celery [16]. Pru p 1 is heat-labile and it is found to be sensitive to gastrointestinal digestion [14]. Thus, only the unprocessed form of the fruit leads to the typical symptoms of OAS, whereas cooked peach is tolerated by patients [16].
