*4.6. Gene Function Annotation*

Gene function was annotated on the basis of the following databases: Nr (NCBI non-redundant protein sequences; ftp://ftp.ncbi.nih.gov/blast/db/FASTA/); Pfam (Protein family; http://pfam. xfam.org/); KOG/COG (Clusters of Orthologous Groups of proteins; http://www.ncbi.nlm.nih.gov/ KOG); Swiss-Prot (A manually annotated and reviewed protein sequence database; http://www. uniprot.org/); KEGG (Kyoto Encyclopedia of Genes and Genomes; http://www.genome.jp/kegg/); GO (Gene Ontology; http://www.geneontology.org/).
