*2.1. Subjects*

Male Sprague Dawley rats (60 days old, ~225 g; Envigo, Jerusalem, Israel) were caged together according to their treatment group (4 per cage; 59 × 28 × 20 cm) at 22 ± 2 ◦C under 12 h light/dark cycles. Plastic hoses were placed in each cage to enrich the animals' environment. For the saccharin preference test, each rat was placed in a separate cage. Rats were allowed water and laboratory rodent food ad libitum.
