*4.1. Borneol*

Identified as a monoterpene, borneol is a terpene derivative that can be found in several plant species, including *Cannabis sativa* L. [34,61,64]. The scent of this aromatic compound has been equated to a woody balsam aroma. Traditional Chinese medicine has employed the therapeutic properties of borneol for thousands of years as a resuscitation drug due to its active orifice-opening effects [72,73]. These effects are hypothesized to enhance blood–brain barrier (BBB) permeability [72–74], allowing for improved drug delivery to the central nervous system [73]. On top of its enhancement of BBB permeability, borneol also possesses anti-microbial, anti-inflammatory, anti-nociceptive, antithrombotic, neuroprotective, and genoprotective effects [75–81].
