**5. Conclusions**

In conclusion, our data show that Gemini-Cur can improve the apoptotic effect of cisplatin on cancer resistant cells. Further studies are needed to figure out the molecular mechanism of synergistic effect of Gemini-Cur/Cis in TNCB cells.

**Author Contributions:** Conceptualization, P.K., H.J.A. and E.B.; methodology, E.B., A.S. and M.A.H.F.; software, P.K., E.B. and G.O.; investigation, P.K. and H.J.A.; writing—original draft preparation, P.K., A.S. and E.B.; writing—review and editing, A.S., G.O. and Z.H.; supervision, E.B. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** Not applicable.

**Informed Consent Statement:** Not applicable.

**Data Availability Statement:** Data is contained within the article.

**Acknowledgments:** Authors would like to thank staff of Genomics & Molecular biology Lab at the University of Tabriz for their technical assistance.

**Conflicts of Interest:** The authors declare no conflict of interest.

**Sample Availability:** Samples of the compounds are available from the authors.

#### **References**

