3.1.1. Chemistry and Sources

Baicalein (5,6,7–trihydroxyflavone) is a naturally occurring polyphenol found in several medicinal plants, in particular in the roots of *Scutellaria baicalensis* G. and *Scutellaria lateriflora* L., and in the seeds, leaves, fruits and bark of *Oroxylum indicum* (L.) Kurz [65,66], all species that grow in several Asian countries. Baicalein is the aglycone of

baicalin (baicalein 7-O-glucuronide), which is also found as such in plants and, moreover, is formed after the biotransformation of baicalein in vivo [65,67].
