Molecular-Based Approaches Used in Therapy for Gastrointestinal Cancers

Dear Colleagues, 

Accumulated fundamental knowledge testifies as to the existence of multiple complex molecular mechanisms in oncogenesis that determine the characteristics of disease progression and affect tumor responses to therapy. Tumor heterogeneity is a fact. Single attempts to cluster cancer using molecular and genetic approaches are adequate, but they are not applied in practical oncology. Increasing the effectiveness of antitumor measures is task of great importance in practical oncology.

New techniques, targeted drugs, and chemotherapy regimens are not always successful due to inherited or acquired resistance to anti-cancer therapy. There is insufficient knowledge of molecular-based approaches in the field of anti-cancer treatment. The main goal of this Special Issue is to summarize practical molecular-based methods used in the therapy of gastric and colorectal cancers.

Prof. Dr. Irina V. Kondakova
Dr. Liudmila V. Spirina
Guest Editors

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• molecular-based therapy
• gastric cancer
• colorectal cancer
• new anti-cancer targets
• response to therapy