Hydrogels for the Regeneration of Joints of the Musculoskeletal System in Orthopedics (2nd Edition)

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: 30 March 2025 | Viewed by 66

Special Issue Editors


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Guest Editor
Tissue Engineering, Orthopeadic Research & Mechanobiology, Department for BioMedical Research (DBMR), Medical Faculty, University of Bern, 3012 Bern, Switzerland
Interests: hydrogels; progenitor cells; regeneration; tissue engineering; bioreactors; mechanobiology; anterior cruciate ligament; cartilage; intervertebral disc; bone
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Guest Editor
Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran
Interests: scaffolds for tissue engineering applications
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Special Issue Information

Dear Colleagues,

Hydrogels for the regeneration or repair of tissues of the musculoskeletal apparatus in orthopedic research are of very high translational value. Various tissues of joint and joint-like tissues warrant applications of hydrogels. The best examples are the regeneration of articular cartilage of the knee or the intervertebral disc (IVD) of the spine. These hydrogels need to be relatively stiff and should be very similar to native tissue in terms of mechanobiological parameters. In orthopedics, there is an urgent need to develop clinically feasible solutions to relieve pain and restore the function of degenerated tissues, such as the spine and other joints, such as the rotator cuff of the shoulder. In the last few decades, smart biomaterials have been investigated which could be injected into degenerated IVD to restore disc height. This Special Issue seeks contributions to the field of engineered hydrogels for orthopedic applications that warrant mechanically reinforced properties by cross-linking and other means. These hydrogels will be targeted for cartilage repair and/or IVD, with a special focus on these micro-environments. These micro-environments warrant special reinforcements or specific adaptations for clinical applications.

Prof. Dr. Benjamin Gantenbein
Prof. Dr. Mohammad Jafar Abdekhodaie
Guest Editors

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Keywords

  • biomaterials
  • 3D cell culture
  • alginate
  • micro-bead
  • cell viability
  • orthopedics
  • stem cells
  • regeneration
  • hyaluronic acid
  • collagen

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