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Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic and Epigenetic Factors for Autoimmune Diseases

edited by

Ulises De La Cruz-Mosso

submission deadline 25 Oct 2025 | Submission Open

Keywords: single nucleotide variants; polymorphism; mutations; microRNAs; HLA genes; cytokine gene; DNA methylation; rheumatoid arthritis; systemic lupus erythematosus; exposome

(This special issue belongs to the Section Epigenomics)

Non-Coding RNAs in Osteoarthritis: From Epigenetic Regulation to Therapeutic Targets

edited by Ioanna Papathanasiou

submission deadline 25 Oct 2025 | Submission Open

Keywords: osteoarthritis; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; therapeutic strategies

(This special issue belongs to the Section RNA)

Epigenetic Dynamics in Cancer and Aging

edited by

Hayan Lee

submission deadline 30 Oct 2025 | Viewed by 50 | Submission Open

Keywords: DNA methylation; histone modification; chromatin 3D modeling; non-coding RNA; long-read sequencing technology; single-cell epigenetics; cancer initiation and development; epigenetic alterations in the aging process; aging-specific epigenetic alterations; cancer-specific epigenetic alterations

(This special issue belongs to the Section Epigenomics)

Genetics and Epigenetics in Susceptibility to Multifactorial Diseases

edited by

Cinzia Ciccacci

and Andrea Latini

submission deadline 30 Oct 2025 | Viewed by 29 | Submission Open

Keywords: multifactorial disorders; genetic factors; epigenetic factors; polymorphisms; gene– gene interactions; gene– miRNA interactions; miRNA; methylation state; genetic susceptibility

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Progress and Applications of Sequencing Technologies

edited by

Domenico Giosa

and Maria Papale

submission deadline 30 Oct 2025 | Viewed by 24 | Submission Open

Keywords: genomics; transcriptomics; epigenomics; metagenomics; bioinformatics; data analysis

(This special issue belongs to the Section Technologies and Resources for Genetics)

Genetics and Genomics of Endocrine Diseases in Children and Adolescents

edited by

Malgorzata Wasniewska

submission deadline 31 Oct 2025 | Viewed by 9 | Submission Open

Keywords: endocrine disease; endocrine gland; genetic syndrome; genetic polymorphism; genetic pathomechanism

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Pharmacogenomics and Personalized Treatment

edited by

Livija Šimičević

and Lana Ganoci

submission deadline 10 Nov 2025 | Viewed by 16 | Submission Open

Keywords: pharmacogenomics; personalized treatment; genetic biomarkers; drug metabolism; gene– drug interactions; genetic variation; clinical pharmacogenomics

(This special issue belongs to the Section Pharmacogenetics)

Application of Sequencing Technologies in Cancers

edited by Limin Chen

submission deadline 20 Nov 2025 | Viewed by 25 | Submission Open

Keywords: sequencing technologies; single-cell; spatial transcriptomics; cancer

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Molecular Adaptation and Evolutionary Genetics in Plants

edited by Wei Zhang

submission deadline 24 Nov 2025 | 1 articles | Viewed by 1161 | Submission Open

Keywords: molecular evolution; plastid genome; mitochondrial genome; nuclear genome; gene family

(This special issue belongs to the Section Plant Genetics and Genomics)

Molecular Genetics and Pathogenesis of Motor Neuron Disease

edited by Tadashi Nakagawa

submission deadline 25 Nov 2025 | 1 articles | Viewed by 551 | Submission Open

Keywords: motor neuron disease; molecular genetics; molecular and cellular analyses; phenotypic characterization; therapeutic development; clinical applications; omic technologies

(This special issue belongs to the Section Neurogenomics)

Plant Genetics, Evolution, Cytogenetics and Cytogenomics for Biodiversity Conservation

edited by

Eric Javier Martínez

Ana Isabel Honfi

and

Anna Reutemann

submission deadline 15 Dec 2025 | 1 articles | Viewed by 446 | Submission Open

Keywords: plant conservation; cytogenetics; cytogenomics; plant evolution; population genetics; genome evolution; chromosomal variation; polyploidy; biodiversity; genomic resources

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetic and Molecular Insights into Cardiovascular Disease: From Mechanisms to Precision Medicine

edited by

Lingfeng Luo

and

Laurent Metzinger

submission deadline 15 Dec 2025 | Viewed by 38 | Submission Open

Keywords: cardiovascular disease; genetic variants; precision medicine; epigenetics; non-coding RNAs; polygenic risk scores; mendelian randomization; biomarkers; genome-wide association studies (GWASs); molecular mechanisms

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Molecular Genetics of Stress Response in Crops

edited by Jie Zhan

submission deadline 15 Dec 2025 | Submission Open

Keywords: crop; abiotic stresses; protein translation; regulation; molecular mechanism; plant hormones

(This special issue belongs to the Section Plant Genetics and Genomics)

Feature Papers in Microbial Genetics and Genomics

edited by

Jose María Requena

submission deadline 20 Dec 2025 | 1 articles | Viewed by 810 | Submission Open

Keywords: virus; bacteria; protists; parasites; genomics; transcriptomics; proteomics; genetics; drug resistance; molecular evolution; data re-analysis

(This special issue belongs to the Section Microbial Genetics and Genomics)

Molecular Mechanisms Responsible for Radiation-Induced Toxicity of Normal Tissue

edited by

Rupak Pathak

submission deadline 25 Dec 2025 | 7 articles | Viewed by 20211 | Submission Open

Keywords: radioresponsive genes; inflammation; genetic markers of radiation damage; immunotherapy; radioprotectors; DNA damage and repair

(This special issue belongs to the Section Toxicogenomics)

Single-Cell and Spatial Multi-Omics in Human Diseases

edited by

Xin Wang

submission deadline 25 Dec 2025 | Viewed by 283 | Submission Open

Keywords: single-cell omics; spatial multi-omics; pathogenesis of disease; biomarkers; computational tools; integrative biology

(This special issue belongs to the Section Bioinformatics)

Current Advances in Inherited Retinal Disease

edited by

Se Joon Woo

submission deadline 25 Dec 2025 | Viewed by 61 | Submission Open

Keywords: inherited retinal diseases; retinitis pigmentosa; macular dystrophy; cone dystrophy; genotype; gene therapy; clinical trial; imaging; genetic mechanism; genome editing; phenotype

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Hereditary Traits and Diseases in Companion Animals

edited by

Lucie Chevallier

and

Marie Abitbol

submission deadline 25 Dec 2025 | Viewed by 25 | Submission Open

Keywords: genetic traits; hereditary diseases; companion animals; spontaneous disease models; veterinary genetics; genetic selection; breed-specific diseases

(This special issue belongs to the Section Animal Genetics and Genomics)

The Function and Molecular Mechanism for Immune Responses in Human Diseases

edited by Zsofia Banlaki

submission deadline 25 Dec 2025 | Viewed by 14 | Submission Open

Keywords: leukocyte cytokine; immune receptor; signal transduction; gene expression; antibody antigen; major histocompatibility; complex complement; system inflammation

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

The 15th Anniversary of Genes: Feature Papers in the "Animal Genetics and Genomics" Section

edited by

Antonio Figueras

and

Pedro Lorite Martínez

submission deadline 31 Dec 2025 | Viewed by 93 | Submission Open

Keywords: applied genetics and genomics in species of economic importance; companion animal genetics and genomics; breeding and genetic selection; genetics and genomics of aquaculture species; genetics of immune response and disease resistance; genome-edited animals and animal epigenetics; animal population genetics; polymorphisms and genome annotation; genetics applied to the interaction of microbiome and genetic traits of interest; bioinformatics analysis in animal genetics; genomics and evolution; cytogenomics

(This special issue belongs to the Section Animal Genetics and Genomics)

The 15th Anniversary of Genes: Feature Papers in the Human Genomics and Genetic Diseases Section

edited by

Gil Atzmon

and

Mariarosa Anna Beatrice Melone

submission deadline 31 Dec 2025 | Viewed by 76 | Submission Open

Keywords: genetics of monogenic diseases and complex diseases; genotype– phenotype relationships; population genomics and genetic epidemiology; precision medicine; pharmacogenetics and pharmacogenomics; targeted genome editing; gene therapy and delivery systems; genetically engineered cell therapy; RNA- and small nucleic acid-based therapeutics; genetic testing and molecular diagnostics; biomarker development and application; genome-wide association studies; epigenetic therapy; developmental genetics; epigenetics; and epigenomics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

The Development of Genetic Assessment for Neurotoxicity

edited by

and

submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open

Keywords: neurotoxicity; genetics; neurodegenerative disorders; mental disorders

(This special issue belongs to the Section Toxicogenomics)

The 15th Anniversary of Genes: Feature Papers in the Population and Evolutionary Genetics and Genomics Section

edited by

Zissis Mamuris

submission deadline 31 Dec 2025 | Viewed by 29 | Submission Open

Keywords: population genetics; evolutionary genomics; genetic diversity; adaptation; natural selection

(This special issue belongs to the Section Population and Evolutionary Genetics and Genomics)

Research Updates in Forensic Genetics

edited by Massimo Lancia

submission deadline 31 Dec 2025 | Submission Open

Keywords: next generation sequencing; single cell analysis; time since deposition; time since death; DNA phenotyping; biogeographic ancestry; age prediction; familial search; disaster victim identification; trace DNA contextualisation

(This special issue belongs to the Section Molecular Genetics and Genomics)

15th Anniversary of Genes: Feature Papers in the “Cytogenomics” Section

edited by

Monica Bullejos

submission deadline 31 Dec 2025 | Submission Open

Keywords: molecular cytogenetics; cytogenomics; microarray; chromosome biology; karyotyping; high-throughput cytogenetics; genome organization; comparative genomics; karyomapping; optical mapping

(This special issue belongs to the Section Cytogenomics)

15th Anniversary of Genes: Feature Papers in the “Plant Genetics and Genomics” Section

edited by

Jacqueline Batley

and

Roberto Tuberosa

submission deadline 31 Dec 2025 | Submission Open

Keywords: epigenetic editing; genetics; genomics; pangenome; plants; QTL mapping; QTL cloning; regulation of gene expression

(This special issue belongs to the Section Plant Genetics and Genomics)

Next-Generation Diagnosis and Treatment of Hematologic Diseases

edited by

Thomas David Daniel Kazmirchuk

and

Ashkan Golshani

submission deadline 15 Jan 2026 | Viewed by 54 | Submission Open

Keywords: hematologic disease; hematology; thrombosis and hemostasis; bleeding disorders; artificial intelligence; next-generation theranostics; therapeutics; diagnostics; peptide design; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Insights into Forensic Genetics

edited by

Simone Grassi

Sarah Gino

and

Paola A. Magni

submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open

Keywords: forenscic genetics; molecular autopsy; forensic omics; post-mortem genetic testing; legal medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Unraveling the Genetic Tapestry of Human Populations: New Insights from Population Genetics and Identification in Anthropology

edited by

Lovorka Barać Lauc

submission deadline 25 Feb 2026 | Submission Open

Keywords: human genetic diversity; population genetics; migration patterns; admixture; isolated populations; ancestry reconstruction; anthropological genomics; biomedical relevance; forensic identification

(This special issue belongs to the Section Population and Evolutionary Genetics and Genomics)

Diagnosis, Management and Therapy of Rare Diseases

edited by Giorgia Girotto

submission deadline 30 Apr 2026 | Viewed by 38 | Submission Open

Keywords: rare and ultrarare genetic diseases; genetic mechanisms; gene-tailored management; personalized therapeutic approaches

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Displaying special issue 151-200 on page 4 of 4.

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