Cultured Cells as Models for Investigating Insecticidal Toxin Action
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 594
Special Issue Editor
Interests: Bacillus thuringiensis; Cry proteins; Lysinibacillus sphaericus; Bin toxin; insect midgut; uptake of protein toxins
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will gather recent research on the uses of cultured cells for investigating insecticidal molecules. While genetic technologies for investigating toxin action in insects have advanced greatly, the handling of insects requires a range of skills and facilities. Cell lines can offset challenges of working in vivo with insects by serving as models for investigating interactions between toxins and affected cells. Investigated cytotoxic molecules could range from protein toxins to small venom peptides, to non-protein natural products. Studies using cultured cells and toxicants could yield insights into mechanisms of action and structure-activity relationships of known toxins, or the discovery of novel toxins. This Special Issue aims to become a reference for studies where cultured cells contribute to a better understanding of insecticidal molecules and their cellular interactions.
Prof. Dr. Michael Adang
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- insecticidal toxins
- Bacillus thuringiensis
- venom
- cultured cells
- cell culture
- Cry proteins
- mode-of-action
- insecticidal
- insecticide
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