Recent Advances and Innovations in Kidney and Pancreas-Kidney Transplantation

Dear Colleagues,

Since the first kidney transplantation in the year 1954 by Joseph Murray in Boston, kidney transplantation has developed into a procedure with brilliant results based on improvements and advances in immunosuppression, surgical transplant techniques, organ allocation, and the optimization of organ procurement.

However, general organ shortage, demographic changes, and a decrease in the number of ideal donors have forced renal transplant centers to push the boundaries and expand the donor pool by accepting marginal donor kidneys, the use of dual kidney transplants, or increasing the number of living donations.

Very recently, the COVID-19 crisis has closed transplant centers, and the long-term consequences in this respect are not yet recognizable.

Within the last several years, the challenge in renal transplantation has become to maintain or even improve the excellent results from the past under worsening conditions by addressing organ quality and long-term transplant success, for example, using machine perfusion, advances in the diagnostics and therapy of immunological complications (antibody-mediated rejection, anti HLA- antibodies, etc.), minimizing immunosuppression, using minimally invasive surgical techniques (e.g., robotic surgery), optimizing anti-infective regimes, and/or rethinking organ allocation and recipient selection.

The advent and progress of artificial renal tissue growth and implantable artificial kidneys could be a hopeful approach for the future.

In this joint Special Issue of the Journal of Clinical Medicine and Transplantology, we want to invite you to describe the recent advances, new technologies, and latest developments in the field of renal and pancreas transplantation.

Original investigations, review articles, and short communications are especially welcome.

Dr. Hans-Michael Hau
Prof. Dr. Christian Hugo
Dr. Julian Stumpf
Guest Editors

Manuscript Submission Information

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• renal transplantation/organ transplantation
• kidney donors
• antibody-mediated rejection
• biomarkers
• donor-specific antibody
• organ procurement
• immunosuppression/immunosuppressive agents
• robotic transplantation/surgery
• machine perfusion
• humans
• antiviral agents/adverse effects/therapeutic use
• opportunistic infections (cytomegalovirus infection
• polyomavirus infection)
• immunocompromised host
• tolerance induction
• organ transplantation/standards
• treatment outcome
• treatment toxicity