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Keywords = 6-epi-monanchorin

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10 pages, 1069 KiB  
Article
Marine Bacterium Vibrio sp. CB1-14 Produces Guanidine Alkaloid 6-epi-Monanchorin, Previously Isolated from Marine Polychaete and Sponges
by Tatyana Makarieva, Larisa Shubina, Valeria Kurilenko, Marina Isaeva, Nadezhda Chernysheva, Roman Popov, Evgeniya Bystritskaya, Pavel Dmitrenok and Valentin Stonik
Mar. Drugs 2019, 17(4), 213; https://doi.org/10.3390/md17040213 - 4 Apr 2019
Cited by 8 | Viewed by 3789
Abstract
Twenty-three bacterial strains were isolated from the secreted mucus trapping net of the marine polychaete Chaetopterus variopedatus (phylum Annelida) and twenty strains were identified using 16S rRNA gene analysis. Strain CB1-14 was recognized as a new species of the genus Vibrio using the [...] Read more.
Twenty-three bacterial strains were isolated from the secreted mucus trapping net of the marine polychaete Chaetopterus variopedatus (phylum Annelida) and twenty strains were identified using 16S rRNA gene analysis. Strain CB1-14 was recognized as a new species of the genus Vibrio using the eight-gene multilocus sequence analysis (MLSA) and genome sequences of nineteen type Vibrio strains. This Vibrio sp. was cultured, and 6-epi-monanchorin (2), previously isolated from the polychaete and two sponge species, was found in the cells and culture broth. The presence of the 6-epi-monanchorin was confirmed by its isolation followed by 1H NMR and HRESIMS analysis. These results showed the microbial origin of the bicyclic guanidine alkaloid 2 in C. variopedatus. Full article
(This article belongs to the Special Issue Selected Papers from the 3rd International Symposium on Life Science)
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