Search Results (165)

Coronavirus anxiety is defined as a psychological contrast characterized by excessive fear, obsessive thoughts, and reassurance-seeking behaviors associated with COVID-19. As current scales have been tested primarily in North American populations, we aimed to translate and culturally adapt three measures of dysfunctional coronavirus anxiety—the Coronavirus Anxiety Scale (CAS), the Obsession with COVID-19 Scale (OCS), and the Coronavirus Reassurance-Seeking Behaviors Scale (CRBS)—for the first time in Greek-speaking populations. To translate existing scales, we followed best practices for cross-cultural comparisons using forward translation (English to Greek) and backward translation (Greek to English) with expert translation review, prior to conducting pilot testing and confirmatory factor analysis in a bespoke survey population. A total of 405 adults from Cyprus participated in this study. The results indicated that the Greek versions of these measures demonstrated adequate reliability (Cronbach’s alphas > 0.70) and strong factor structure, as supported through confirmatory factor analysis. However, only the CAS exhibited evidence of both convergent and divergent validity. Our study makes several innovative contributions which have broad implications for crisis preparedness, including providing a framework for mental health interventions in future pandemics or Black Swan events. Full article

Viral infections have been implicated in psychiatric outcomes through immune-mediated pathways. This 12-month prospective cohort study, designed as a pilot and hypothesis-generating investigation, compared psychiatric symptoms and inflammatory cytokine profiles in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), hepatitis C virus (HCV), and tick-borne encephalitis virus (TBEV), and explored their potential predictive value. Thirty-seven patients hospitalized with viral infections and 32 healthy controls were evaluated, acknowledging the limited sample size. Psychiatric interviews and the Hospital Anxiety and Depression Scale (HADS) were used for assessment. The study was divided into two stages. In Stage 1, during the acute infection, a psychiatric assessment was conducted, and cytokine levels were measured in the patients’ blood. In Stage 2, one year later, the psychiatric assessment was repeated. No significant differences were found in psychiatric diagnosis rates or symptom severity between infection groups, regardless of viral type or neuroinvasive capacity. However, these findings should be interpreted as preliminary given the limited sample size. Some cytokines, eg., interleukin-1β (IL-1β), tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), and soluble interleukin-2 receptor subunit alpha (sIL-2Rα), showed associations with individual symptoms, but these were inconsistent and did not demonstrate robust predictive value. Cluster analysis identified two distinct inflammatory profiles—one characterized by higher cytokine levels (predominantly in Coronavirus disease 2019 (COVID-19) and TBEV cases) and the other by lower cytokine levels (mostly in HCV and controls). However, different cytokine profiles did not correspond to clinical outcomes. The results suggest that psychiatric sequelae after viral infections are not directly driven by specific cytokines or infection type but rather emerge from a complex interaction of immune, psychological, and environmental factors. Single cytokine measurement is insufficient and cannot be used as a tool for assessing the risk of developing psychiatric disorders. Given the exploratory nature of the study, all results require confirmation in larger, adequately powered cohorts. Future studies should focus on composite biomarkers and systems-based models such as neuroimmune-metabolic-oxidative pathways (NIMETOX), or Immune-Inflammatory Response System (IRS)/Compensatory Immune Response System (CIRS)/Oxidative & Nitrosative Stress (O&NS) for improved predictive accuracy. Full article

Background/Objectives: Food insecurity and mental health are two important issues affecting college students, and their incidence have increased since the coronavirus disease (COVID-19) pandemic. The objective of this study was to examine the association between food insecurity and the mental health outcomes among college students in the Bronx, NY. Methods: The study utilized a cross-sectional design. Data were collected from 710 undergraduate students, using a self-administered survey with a quick response (QR) code. The survey consisted of sociodemographic questions, the US Household Food Security Survey Module (ten-item questionnaire), and the Depression, Anxiety, and Stress Scale (DASS-21). Data were analyzed using Statistical Package for the Social Sciences (SPSS), Version 29. Results: Results of the study indicated that 53% of the participants were food insecure, 47.4% had high depressive symptoms, 46.2% had high anxiety, and 50.6% had high stress levels. Multiple logistic regression revealed the reciprocal association between food insecurity and mental health. Students who were stressed (p = 0.022) were likely to experience food insecurity, while those who were food insecure were more likely to experience stress (p = 0.007) and depression (p < 0.021). Students who identified as Black (p = 0.021) and had lower income (p = 0.031) were more likely to be food insecure. Conclusions: This research shows that food insecurity worsens mental health, and mental health worsens food insecurity. However, it was not possible for us to establish causality between the two variables. Full article

Objectives: To evaluate the effects of respiratory exercises and stabilization techniques on patients with coronavirus disease 2019 (COVID-19). Methods: This is a quasi-experimental study and a single community-based hospital. Thirty-nine patients with COVID-19 completed the study, of which 20 underwent respiratory exercises and stabilization techniques, while the rest (19 patients) did not. Respiratory exercises and stabilization techniques comprised diaphragmatic breathing, pursed-lip breathing, square box breathing, huff coughing, and progressive muscle relaxation. Outcomes were assessed using the Modified Borg Scale (MBS), the Breathlessness, Cough, and Sputum Scale (BCSS), and the Hospital Anxiety and Depression Scale (HADS) for mental health. Questionnaires were administered at admission, discharge, and 6 months after discharge. Results: Patients who received respiratory exercises and stabilization techniques showed significant improvements in MBS (p = 0.0001) and BCSS scores (p = 0.002) at discharge. However, there were no significant long-term effects on these physical symptoms. Significant interaction in HADS scores were also observed. Conclusions: Although there were no significant long-term effects, respiratory exercises and stabilization techniques resulted in short-term improvements in the physical and mental health of patients with COVID-19. Full article

Cardiovascular diseases (CVDs) are among the most common comorbidities in COVID-19 patients. This multicenter cross-sectional study assessed knowledge, risk perception, precautionary measures, and psychological burden related to COVID-19 among Lebanese individuals with and without CVD during the pandemic’s first wave. A total of 485 CVD patients and 1033 control group (CG) participants completed standardized questionnaires, including the Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder-7 (GAD-7), and Coronavirus Anxiety Scale. Compared to CG, CVD patients demonstrated significantly lower COVID-19-related knowledge (86.4% vs. 90.0%, p < 0.001) and adherence to preventive measures (81.5% vs. 85.7%, p < 0.001). After stratification, limited knowledge was more common among CVD patients (45.7% vs. 31.8%), as was limited precautionary behavior (70.3% vs. 54.2%). Risk perception was suboptimal in both groups, with no significant difference (41.3% vs. 38.6%, p = 0.072). Anxiety (GAD-7 ≥ 10) and depression (PHQ-9 ≥ 10) were more prevalent among CVD patients (13.4% and 11.3%) than CG participants (9.5% and 16.5%). Survey outcomes were influenced by educational, socioeconomic, and psychosocial factors. These findings highlight the need to target CVD patients in public health campaigns to enhance preparedness and mental health support during pandemics. Full article

Background: Women with systemic autoimmune rheumatic disease (SARD) are at higher risk of developing infection-related complications, anxiety, and depression. Using the example of the COVID-19 pandemic, we aimed to explore the impact of this external stressor on symptoms of depression, anxiety, and stress in a sample of women with SARD in a cross-sectional study design. Methods: Females aged 18–50 with SARD were enrolled from 04/2021 to 04/2022 at the Medical University of Vienna or through an online self-help group, while snowball sampling was used to recruit an age-matched healthy control group. Participants completed questionnaires including: (1) demographic information, medical history, and access to healthcare; (2) the Depression, Anxiety, and Stress Scale (DASS-21); and (3) the Coronavirus Anxiety Scale (CAS). Parameters were compared between groups using Chi-squared, Fisher’s exact, and Mann–Whitney U tests. Linear regression analysis was used to investigate which individual factors predicted the DASS-21 in women with SARD. Results: The study sample consisted of 226 women (n = 99 with SARD and n = 127 healthy controls). Women with SARD reported lower DASS-21 stress (p = 0.008) and CAS scores (p = 0.057) than the control group. There were no significant differences in DASS-21 anxiety or depression scores. Among women with SARD, a linear regression model identified the most important predictors of DASS-21 as access to rheumatological care (p = 0.002) and recent disease activity (p = 0.028). Conclusions: Despite the pandemic, women with SARD reported mental health outcomes equal to or better than those of the healthy control group. Continued access to rheumatological care may serve as an important protective factor for their mental health during large-scale crises like pandemics. Full article

Background/Objectives: COVID-19, caused by the SARS-CoV-2 virus, emerged in late 2019 and rapidly became a global pandemic, affecting over 200 countries. The pandemic has had profound impacts on global health, the economy, and mental health, leading to increased anxiety and more cases of posttraumatic stress disorder in the general population. This study aimed to evaluate the factors influencing the long-term psychological effects, both positive and negative, seen in the late stages of the COVID-19 pandemic in Poland (starting in the second half of 2021). It combined specific COVID-19 anxiety factors with a broader general mental health assessment to identify significant associations. Methods: Data were collected from 416 participants through paper-based and online questionnaires, with 235 valid responses gathered in total. This study utilized the Coronavirus Anxiety Scale; General Health Questionnaire (GHQ-28); and, to study Positive Trauma Effects (PTEs) and Negative Trauma Effects (NTEs), the Changes in Outlook Questionnaire. Data analysis was performed using the R language and a Generalized Additive Model analysis was also performed. Results: The study found generally low levels of COVID-19 anxiety and mental distress among participants. Significant predictors of NTEs included COVID-19 anxiety and general mental health status, which explained 47% of the variance. PTEs were significantly associated with gender, with women experiencing higher PTE levels relative to men. Conclusions: The findings indicate that combining specific ailment anxiety measurements with general mental health assessments enhances our ability to predict Negative Trauma Effects. Addressing mental health symptomatology and well-being during mass health crises is crucial to mitigate long-lasting psychological damage. Full article

Coronavirus disease 2019 (COVID-19) presents with various symptoms, and some patients develop post-COVID-19 condition (PCC). Vitamin D has shown therapeutic potential in COVID-19 and may offer benefits for PCC. The aim of this study was to evaluate the differences associated with two supplementation strategies (bolus and daily) on interleukin-6 (IL-6) levels, glutathione peroxidase (GPx) activity, and clinical outcomes in PCC patients, regardless of whether target 25 (OH) D levels reached the ideal range. We conducted a self-controlled study in which 54 participants with PCC were supplemented with vitamin D₃ (n = 28 bolus and n = 26 daily) for 2 months. Blood samples were collected to measure IL-6 levels and GPx activity using spectrophotometric methods. The Hospital Anxiety and Depression Scale (HADS) was used to assess mental function. Both bolus and daily vitamin D supplementation were significantly associated with increased GPx activity and decreased IL-6 levels. Daily supplementation was additionally associated with a significant reduction in anxiety and depression scores. However, neither regimen was associated with improvements in cough, dyspnea, or fatigue. These findings suggest a potential association between vitamin D supplementation and improvements in antioxidant and neuropsychiatric parameters in PCC, possibly mediated by its immunomodulatory and antioxidant properties. Further placebo-controlled trials are warranted to determine whether these observed associations reflect causal relationships. Full article

Background/Objectives: The existing literature has described the common symptoms and long-term effects of coronavirus disease (COVID-19). However, there is a lack of detailed information on how different degrees of disease severity affect survivors differently. This study aims to fill that gap by evaluating the symptoms, physical activity, and functionality of COVID-19 survivors across a spectrum of severity levels, comparing them with those of healthy individuals. Methods: An observational study was carried out following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) criteria and checklist. Participants were divided into 5 groups based on COVID-19 severity according to the World Health Organization classification: healthy (COVID-19-negative), mild (symptomatic without pneumonia or dyspnoea), moderate (pneumonia and dyspnoea without hospitalisation), severe (severe pneumonia requiring hospitalisation), and critical (severe pneumonia with admission to the intensive care unit). Descriptive variables, symptoms (Fatigue Borg Scale, Fatigue Impact Scale, Fatigue Severity Scale, Dyspnoea Borg Scale, Visual Analogue Scale, Hospital Anxiety and Depression Scale, and European Quality of Life-5 Dimensions), physical activity (the International Physical Activity Questionnaire) and functionality (Patient-Specific Functional Scale, Short Physical Performance Battery, Arm Curl test, and 2 min step test) were measured. Results: A total of 304 participants were included: healthy (n = 42), mild (n = 143), moderate (n = 49), severe (n = 52), and critical (n = 18) COVID-19 patients. The impact of COVID-19 on surviving patients varies significantly with the severity of the disease. The results show that the hospitalisation time, age, and comorbidities of the patients are greater in those with a greater severity of the disease. Patients with more severe COVID-19 also experience greater frailty, dysphagia, fatigue, dyspnoea, and pain. Additionally, those with severe cases have poorer overall health, reduced physical activity, and diminished functionality. No evidence of post-COVID-19 anxiety or depression is found in the sample, even considering the timeframe between the negative test and the assessment. Conclusions: Patients with higher COVID-19 severity (severe or critical) experience more symptoms than those with lower COVID-19 severity (mild or moderate). Additionally, those with severe cases have poorer overall health, reduced physical activity and diminished functionality. Register: Clinicaltrials.gov: NCT05731817. Full article

Background/Objectives: The COVID-19 pandemic has profoundly disrupted mental health globally, affecting individuals across all age groups. Understanding its long-term impact is crucial for identifying age-specific vulnerabilities and informing targeted mental health interventions. This longitudinal study aimed to investigate the within-person changes in mental health across different age groups in Greece from the first to the third pandemic wave of coronavirus disease 2019 (COVID-19) (i.e., one year later) during nationwide lockdowns. It further compared the mental health outcomes of three distinct age groups, stratified based on their vulnerability to COVID-19—younger adults (18–29 years), adults (30–59 years), and older adults (60–84 years)—and examined correlates of depression and anxiety during the third pandemic wave. Methods: A total of 720 participants—92 younger adults, 543 adults, and 85 older adults—completed the same set of questionnaires during the first (April–May 2020) and third (March–May 2021) pandemic-related lockdowns. At both time points, participants provided data on the Generalized Anxiety Disorder-2, Patient Health Questionnaire-2, Systemic Clinical Outcome and Routine Evaluation-15, Connor–Davidson Resilience Scale-2, and demographic information. Results: Results indicated a within-individual increase in depression and a decrease in resilience for all participants, irrespective of age. Anxiety increased only among younger adults and adults, whereas family functioning remained stable across all age groups one year post-pandemic onset. Furthermore, younger adults reported higher levels of depression and anxiety, lower resilience, and more impaired family functioning compared to the older age groups in both lockdowns. Among the different age groups, factors independently associated with depression and anxiety were identified through stepwise regression analyses. Conclusions: The present study provides evidence for mental health deterioration during the pandemic across all age groups, with younger adults exhibiting heightened vulnerability. Full article

Background/Objectives: Social isolation and health-related consequences of the COVID-19 pandemic may have significantly impacted quality of life in people with Parkinson’s disease (PwPD). The effect of the COVID-19 pandemic specifically on subjective cognition and social functioning in PwPD is poorly understood. We conducted a longitudinal analysis of changes in subjective cognitive and social functioning in PwPD before (T1, 2017–2019) and during (T2, 2021) the COVID-19 pandemic. Methods: At T1, 347 PwPD completed online surveys. At T2, 123 of them (54 males, 69 females) responded to follow-up questionnaires including Quality of Life in Neurological Disorders (Neuro-QoL) subscales, Beck Depression Inventory-II, Parkinson’s Anxiety Scale, motor and non-motor experiences of daily living from the MDS-Unified Parkinson’s Disease Rating Scale, and the Coronavirus Impact Scale. Results: T1–T2 declines in subjective cognition and social functioning both were correlated with more anxiety, fatigue, and motor symptoms. Additionally, declines in subjective cognition correlated with depression, and with decline in social functioning. Women reported greater COVID-19 impact than men, unrelated to cognition and social functioning; in men, personal experience with COVID-19 was associated with decline in subjective cognition. Conclusions: Our finding that subjective cognition and social functioning are associated with different motor and non-motor symptoms of PD suggests that the impacts of PD on subjective cognition and social functioning are complex, which has important implications for treatment. Full article

Background/Objectives: The mechanisms linking eating attitudes to well-being and physical activity objectives have increasingly attracted the attention of researchers in recent years. This research is particularly significant in the context of the COVID-19 pandemic, which has profoundly disrupted eating habits, exercise routines, and psychosocial well-being across the globe. Additionally, these variables are influenced by cultural dimensions, such as individualism in Poland and collectivism in China. These two countries represent distinct approaches to social health and well-being during the pandemic, offering valuable comparative insights into how cultural contexts shape mental and physical health behaviors; Methods: The study included 644 Polish and 690 Chinese participants. It utilized the Psychological Well-Being Scale (PWBS), the Coronavirus Anxiety Scale (CAS), the Eating Attitudes Test (EAT-26), and the Inventory of Physical Activity Objectives (IPAO); Results: The results indicate that both COVID-19 anxiety and eating attitudes fully mediate the relationship between well-being and physical activity objectives. Full mediation implies that the observed relationship between well-being and physical activity objectives operates entirely through the mediators. Notably, the mediating effect of COVID-19 anxiety was observed only in the Chinese sample, highlighting cultural differences in coping mechanisms and societal responses to anxiety. Cultural differences significantly influenced well-being and physical activity objectives, while eating disorders remained unaffected by cultural and social differences. Additionally, a significant positive correlation was found between COVID-19 anxiety, eating attitudes, and health-related physical activity objectives, underscoring the interplay between mental health and physical activity; Conclusions: These findings underscore the importance of addressing anxiety and eating attitudes to enhance well-being and physical activity behaviors. The study provides a strong theoretical basis for targeted interventions tailored to cultural contexts. Potential limitations include the reliance on self-reported data and differences in demographic characteristics between the Polish and Chinese samples, which may affect generalizability. Full article

Background: In the aftermath of the Coronavirus pandemic and the resulting lockdown and social distancing policies, a new form of work, already existing in the past, has been further enlarged. Teleworking is “full- or part-time electronic work, on-line or off-line, performed at home by self-employed or office workers” and today represents an important lever for companies, including for sustainability, allowing employees to work flexibly, efficiently and remotely. The relationship between telework and sustainability in economic, social, and environmental aspects is also being questioned. The aim of this systematic review is to investigate the effects this has had on workers’ mental health. Methods: PRISMA guidelines were followed. The research was performed on Pubmed and Scopus without restrictions on study type and time limits. The methodological quality of the studies included was assessed using AMSTAR-2, INSA and NOS scales. A meta-analysis of the main adverse effects found in observational studies was also carried out. Results: A total of 38 articles were included in the systematic review. A large proportion of the studies examined showed a correlation between teleworking and worsening mental health. The meta-analysis showed increased levels of mental ill-health (38.8%), stress (28.4%), isolation (6.3%), anxiety (23%), depression (22.6%), work–family conflicts (19.5%), poor sleep quality (56.4%), fatigue (16.1%) and irritability (39.6%). Conclusions: Although most of the works analyzed show a deterioration in the mental health of workers, positive effects were noted in some. There is the need for more studies to optimally investigate the cause–effect relationship between teleworking and mental health deterioration. Full article

Background and Objectives: It is well known that depression, anxiety, and impulsiveness are interrelated; however, studies that have assessed their association with the coronavirus outbreak are scarce. Hence, our study aimed to evaluate the impulsivity incidence and its correlation with anxiety and depression following COVID-19 infection between November 2022 and June 2023. Materials and Methods: The 201 participants completed the Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HAM-A), Sheehan Disability Scale (SDS), and short UPPS-P scales (urgency, premeditation, perseverance, sensation seeking, and positive urgency) to allow us to determine their anxiety and depression symptoms, functional impairment, and impulsivity, respectively. Results: Among our respondents, 22%, and 26.7% had moderate to severe anxiety and depression. The short UPPS-P scale significantly correlated with the HAM-A and HDRS scales. Participants with positive COVID-19 infection showed significantly higher functional impairment scores, especially in the work/study domain (mean (SD): 3.12 (2.2) vs. 2.43 (2.3); p = 0.037). COVID-19-related disruption significantly correlated with negative and positive urgency, HAM-A, HDRS, and the SDS total and subscales. Conclusions: Our findings showed a notable increase in anxiety, depression, and functional impairment among the population following COVID-19 infection. Our research highlights the correlation between impulsivity and the psychological distress experienced following the pandemic. Full article

Background and Objectives: Amidst the COVID-19 pandemic, concerns about the psychological impact of disease-related anxiety on public health have risen. This study aims to compare general and death anxiety levels between acute coronary artery syndrome and COVID-19 pneumonia patients. Materials and Methods: A cross-sectional study of 132 individuals, including acute myocardial infarction (MI), COVID-19 pneumonia patients, and healthy volunteers from Trakya University Hospital (Turkey), was analyzed. Validated scales like the Beck Anxiety Inventory (BAI), Coronavirus Anxiety Scale Short Form, and Thorson–Powell Death Anxiety Scale (TPDAS) were employed. Demographic data such as age, gender, income levels, employment status, presence of a close relative with COVID-19, and whether participants followed COVID-19-related news were collected and compared across groups with significance level of 0.05 set for all analyses. Results: Among 41 COVID-19, 41 MI, and 50 healthy subjects, the pneumonia group showed highest COVID-19 anxiety (p = 0.01) and BAI scores (p = 0.008). Both COVID-19 and MI patients had significantly higher BAI and TPDAS scores compared to healthy controls (p < 0.001). Factors like female gender (p = 0.004), low education (p = 0.003), current employment (p = 0.008), and low income (p = 0.002) correlated with higher BAI scores. Low income (p = 0.001) and COVID-19 news exposure (p = 0.002) correlated with higher TPDAS scores. Males and married patients had lower anxiety scores (p = 0.008). High income, education, and employment reduced anxiety levels (p = 0.008). TPDAS scores decreased with higher income (p = 0.001), but increased in the MI group (p = 0.002) with COVID-19 news exposure. The multivariate linear regression analysis found that MI and COVID-19 pneumonia were associated with TPDAS; female gender, university education, and COVID-19 pneumonia with the Beck scale; and COVID-19 pneumonia with anxiety scores on the COVID-19 Anxiety scale. Conclusions: This research showcases differing anxiety patterns between illnesses such as MI and COVID-19 pneumonia amidst the pandemic, emphasizing the amplifying influence of media coverage on death-related anxieties. It underscores the imperative of targeted interventions and socioeconomic considerations in managing psychological consequences and formulating responsive public health strategies. Full article