631 Results Found

JC-1, a cationic fluorescent dye when added to living cells, is known to be localized exclusively in mitochondria, particularly in good physiological conditions characterized by sufficient mitochondrial membrane potential (ΔΨ). The accumula...

The JC polyoma viral coat protein VP1 was analyzed for amino acid sequences homologies to the IDSP sequence which mediates binding of VLA-4 (integrin alpha 4) to vascular cell adhesion molecule 1. Although the full sequence was not found, a DSP seque...

Plant fatty acyl-acyl carrier protein (ACP) thioesterases terminate the process of de novo fatty acid biosynthesis in plastids by hydrolyzing the acyl-ACP intermediates, and determine the chain length and levels of free fatty acids. They are of inter...

Previous studies have identified numerous transcription factors involved in drought response, each of which play different roles in plants. The objective of the present study was to evaluate the effectiveness of two transcription factors on drought r...

The objective of our study is to generalize the results on product states of the tensor product of two JC-algebras to infinite tensor product JC-algebras. Also, we characterize the tracial product state of the tensor product of two JC-algebras, and t...

Cancer is the second leading cause of mortality worldwide. The study of DNA tumor-inducing viruses and their oncoproteins as a causative agent in cancer initiation and tumor progression has greatly enhanced our understanding of cancer cell biology. T...

A fungal strain (JC-1) of Simplicillium was isolated from a pod of oilseed rape (Brassica napus) infested with the blackleg pathogen Leptosphaeria biglobosa. This study was done to clarify its taxonomic identity using morphological and molecular appr...

Mulberry leaves contain polysaccharides, phenols, alkaloids, and other active ingredients which have medicinal and edible value. In this study, fermented mulberry leaf powder was prepared by solid-state fermentation using Pediococcus pentosaceus JC30...

Since damage evolutions of materials play important roles in simulations, such as ballistic impacts and collisions, a new experimental and numerical method is established to determine the revised Johnson–Cook (JC) failure parameters of a 2618 a...

Polymethyl methacrylate (PMMA) polymer is widely used in various fields today. In order to reveal the structural impact performance of PMMA materials in underwater engineering thoroughly, this paper firstly proposed a simplified plate model for a sph...

In the fifty years since the discovery of JC polyomavirus (JCPyV), the body of research representing our collective knowledge on this virus has grown substantially. As the causative agent of progressive multifocal leukoencephalopathy (PML), an often...

JC polyomavirus (JCPyV) causes a lifelong persistent infection in the kidney in the majority of the population. In severely immunocompromised individuals, JCPyV can become reactivated, spread in the central nervous system, and infect glial cells, ast...

JC polyomavirus (JCPyV) infects the majority of the population and initially establishes a persistent but asymptomatic infection of the kidneys. In healthy individuals, the infection remains controlled by the host immune system, but for individuals e...

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by reactivation of dormant JC polyomavirus (JCPyV). PML was mainly observed in immunocompromised individuals, such as HIV-positive...

The JC polyomavirus virus (JCPyV) affects more than 80% of the human population in their early life stage. It mainly affects immunocompromised individuals where virus replication in oligodendrocytes and astrocytes may lead to fatal progressive multif...

The JC polyomavirus (JCPyV/JCV) is a member of the Polyomaviridae family and is ubiquitious in the general population, infecting 50–80% of individuals globally. A primary infection with JCV usally results in an asymptomatic, persistent infection that...

The organization and dynamics of plasma membrane receptors are a critical link in virus-receptor interactions, which finetune signaling efficiency and determine cellular responses during infection. Characterizing the mechanisms responsible for the ac...

JC virus (JCV), as an archetype, establishes a lifelong latent or persistent infection in many healthy individuals. In immunocompromised patients, prototype JCV with variable mutations in the non-coding control region (NCCR) causes progressive multif...

The polyomaviruses that infect humans, JC virus (JCV) and BK virus (BKV), can establish persistent infections in the cells that make up the renal system, causing nephritis and BKV-associated nephropathy in up to 10% of renal transplant patients, and...

JC virus (JCV) replicates within the nuclei of glial cells in the human brain and causes progressive multifocal leukoencephalopathy. JCV possesses a small, circular, double-stranded DNA genome, divided into early and late protein-coding regions. The...

JC polyomavirus (JCPyV) is the causative agent of the fatal, incurable, neurological disease, progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult population as a persistent, asymptotic infection in the kidneys....

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by the JC polyomavirus (JCPyV). Based on the clinical criteria, PML is diagnosed via polymerase chain reaction (PCR) detection of JCPyV DNA in cerebrospinal fluid (CSF...

BK (BKPyV) and JC (JCPyV) polyomaviruses are widespread in humans. Transmission at an early age and the role of parents in spreading these viruses through the family are incompletely understood. Our aim was to determine the seroprevalence of BKPyV an...

The JC polyomavirus (JCV) has been repeatedly but discordantly detected in healthy colonic mucosa, adenomatous polyps, and colorectal cancer (CRC), and proposed to contribute to oncogenesis. The controversies may derive from differences in JCV target...

For the implementation of simulations for large plastic deformation processes such as cutting and impact, the development of the constitutive models for describing accurately the dynamic plasticity and damage behaviors of materials plays a crucial ro...

JC polyomavirus (JCPyV) establishes a persistent, asymptomatic kidney infection in most of the population. However, JCPyV can reactivate in immunocompromised individuals and cause progressive multifocal leukoencephalopathy (PML), a fatal demyelinatin...

Physic nut (Jatropha curcas L.) has attracted extensive attention because of its fast growth, easy reproduction, tolerance to barren conditions, and high oil content of seeds. SWEET (Sugar Will Eventually be Exported Transporter) family genes contrib...

Joint communication and sensing (JCS) is becoming an important trend in 6G, owing to its efficient utilization of spectrums and hardware resources. Utilizing echoes of the same signal can achieve the object location sensing function, in addition to t...

Mitochondria are the energy factories of a cell, and depending on the metabolic requirements, the mitochondrial morphology, quantity, and membrane potential in a cell change. These changes are frequently assessed using commercially available probes....

Constitutive equations were recognized for AZ31B magnesium alloy at higher temperatures and strain rates from conventional empirical models like the original Johnson–Cook (JC), modified JC, and modified Zerilli–Armstrong (ZA) models for c...

The Johnson-Cook (J-C) constitutive model, including five material constants (A, B, n, C, m), and the Coulomb friction coefficient (μ) are critical preprocessed data in machining simulations. Before they become reliable preprocessed data, investig...

Numerical simulation of impact and shock-wave interactions of deformable solids is an urgent problem. The key to the adequacy and accuracy of simulation is the material model that links the yield strength with accumulated plastic strain, strain rate,...

To accurately assess the effect of different plate thicknesses on the residual stress field of laser shock peened GH3039 superalloy, residual stress measurements were performed on GH3039 alloy plates with thicknesses of 2 mm and 5 mm after laser shoc...

Owing to potential inaccuracies in the current stress–strain curve used for constructing the Johnson–Cook (JC) constitutive model of amorphous alloys, the parameters of the JC constitutive equation were derived using Oxley’s cutting...

The predictions of mechanical responses (stress–strain variations) in the machining of Ti-6Al-4V alloy are important to analyze the deformation conditions of machining to optimize the machining parameters and investigate the generation of a mac...

Titanium alloy is a crucial structural material in the modern aerospace field due to its strong corrosion resistance and strength, low density, and reduced sensitivity to vibration load and impact load, as well as its ability to resist expansion in t...

Bacterial structures formed from the outer membrane and the periplasm components carry biomolecules to expel cellular material and interact with other cells. These outer membrane vesicles (OMVs) can encapsulate bioactive content, which confers OMVs w...

An understanding of the dynamic behavior of materials plays a crucial role in machining improvement. According to the literature on this issue, one of the alloys whose dynamic behavior has been investigated less is AA 5052-H34, despite its numerous i...

AA6082 alloys play a significant role in advancing sustainable development goals (SDGs) by contributing to environmental sustainability, economic growth, and social well-being. These alloys are highly recyclable and align with SDG 12 by promoting res...

This paper, based on the Johnson–Cook damage model, investigates the damage mechanism of high-strength steel tailor welded blanks (TWBs) (Usibor1500P and Ductibor500) during the forming process. Initially, specimens with varying notch sizes were desi...

A comprehensive understanding of the dynamic behavior of materials and structures under impact loads is paramount for the design and maintenance of reliable marine pipelines and associated structures. However, there is a lack of comprehensive researc...

Aluminum alloy laminates have extensive applications in protective armor systems. A simulation-based approach was employed to investigate the anti-penetration performance of aluminum alloy laminates with different configurations. Experiments were car...

The Worldwide harmonized Light duty Test Procedure saw its light first as the United Nations Economic Commission for Europe Global Technical Regulation in 2017. However, it remains unclear how much the deviation is between the actual and test fuel ec...

Diacylglycerol acyltransferase (DGAT) is the only enzyme that catalyzes the acyl-CoA-dependent acylation of sn-1, 2-diacylglycerol (DAG) to form triacylglycerol (TAG). The two main types of DGAT enzymes in the woody perennial biofuel plant Jatropha c...

The John Cunningham virus (JCV) is a polyomavirus that usually infects people at a young age and does not cause any symptoms in immunocompetent individuals. However, in immunocompromised individuals, such as kidney transplant recipients, JCV can caus...

Protein misfolding is a common basis of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Misfolded proteins, such as TDP-43, FUS, Matrin3, and SOD1, mislocalize and form the hallmark cytoplasmic and nuclear inclusions in...

The peak shear strength of a rock joint is an important indicator in rock engineering, such as mining and sloping. Therefore, direct shear tests were conducted using an RDS-200 rock direct shear apparatus, and the related data such as normal stress,...

Background and Objectives: John Cunningham polyomavirus (JCPyV) is a highly prevalent virus in the human population. The prevalence of JCPyV in patients with central nervous system disorders has not been examined extensively. The aim of this study wa...

The increased presence of resistant microorganisms in water promotes the need for supplementary measures to mitigate the water source’s contamination. Traditional treatments are inefficient in wastewater management at removing some emerging con...

In order to investigate the static and dynamic mechanical properties of TC18 titanium alloy, the quasi-static stress–strain curve of TC18 titanium alloy under room temperature was obtained by DNS 100 electronic universal testing machine (Changc...