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294 Results Found

  • Article
  • Open Access
4 Citations
5,982 Views
17 Pages

Energy Efficiency Perspectives of PMR Networks

  • Marco Dolfi,
  • Simone Morosi,
  • Pierpaolo Piunti and
  • Enrico Del Re

23 December 2016

Recently, the concern about energy efficiency in wireless communications has been growing rapidly. Manufacturers and researchers have developed innovative solutions, highlighting the benefits in reducing operational expenditures (OPEX) and carbon foo...

  • Article
  • Open Access
16 Citations
4,592 Views
12 Pages

Photocatalytic Membrane Reactor (PMR) for Virus Removal in Drinking Water: Effect of Humic Acid

  • Rong Cheng,
  • Liangjie Shen,
  • Qi Wang,
  • Shaoyu Xiang,
  • Lei Shi,
  • Xiang Zheng and
  • Wenzhou Lv

16 July 2018

In the actual water environment, the health risk of waterborne viruses is evaluated to be 101–104 times higher at a similar level of exposure compared with bacteria and has aroused strong concern in many countries in the world. Photocatalytic m...

  • Review
  • Open Access
168 Citations
16,413 Views
30 Pages

25 July 2017

The lack of access to clean water remains a severe issue all over the world. Coupling photocatalysis with the membrane separation process, which is known as a photocatalytic membrane reactor (PMR), is promising for water treatment. PMR has developed...

  • Article
  • Open Access
11 Citations
3,288 Views
11 Pages

Acinetobacter baumannii under Acidic Conditions Induces Colistin Resistance through PmrAB Activation and Lipid A Modification

  • Seo-Yeon Ko,
  • Nayeong Kim,
  • Seong-Yong Park,
  • Seong-Yeop Kim,
  • Minsang Shin and
  • Je-Chul Lee

Colistin is a last-resort antimicrobial agent for treating carbapenem-resistant Acinetobacter baumannii infections. The activation of PmrAB by several environmental signals induces colistin resistance in Gram-negative bacteria. This study investigate...

  • Article
  • Open Access
4 Citations
3,699 Views
14 Pages

Possible Role of the Ca2+/Mn2+ P-Type ATPase Pmr1p on Artemisinin Toxicity through an Induction of Intracellular Oxidative Stress

  • Onnicha Pongwattanakewin,
  • The Phyu,
  • Suchanya Suesattayapirom,
  • Laran T. Jensen and
  • Amornrat N. Jensen

29 March 2019

Artemisinins are widely used to treat Plasmodium infections due to their high clinical efficacy; however, the antimalarial mechanism of artemisinin remains unresolved. Mutations in P. falciparum ATPase6 (PfATP6), a sarcoplasmic endoplasmic reticulum...

  • Article
  • Open Access
19 Citations
5,060 Views
17 Pages

CRISPR/Cas9-Based Knock-Out of the PMR4 Gene Reduces Susceptibility to Late Blight in Two Tomato Cultivars

  • Ruiling Li,
  • Alex Maioli,
  • Zhe Yan,
  • Yuling Bai,
  • Danila Valentino,
  • Anna Maria Milani,
  • Valerio Pompili,
  • Cinzia Comino,
  • Sergio Lanteri and
  • Alberto Acquadro
  • + 1 author

22 November 2022

Phytophthora infestans, the causal agent of late blight (LB) in tomato (Solanum lycopersicum L.), is a devastating disease and a serious concern for plant productivity. The presence of susceptibility (S) genes in plants facilitates pathogen prolifera...

  • Review
  • Open Access
12 Citations
5,920 Views
11 Pages

3 November 2020

Background: Polymyalgia Rheumatica (PMR) is one of the most frequent rheumatologic immune-related adverse effects (IRAEs) in cancer patients following therapy with immune checkpoint inhibitors (ICIs). Atypical findings in many patients often lead to...

  • Perspective
  • Open Access
23 Citations
4,926 Views
9 Pages

30 August 2019

Objectives: to evaluate incidence and prevalence rates of polymyalgia rheumatica (PMR) in Italy, depending on the epidemiological methodology used from time to time. Materials and Methods: A comprehensive literature search in MEDLINE and EMBASE was c...

  • Systematic Review
  • Open Access
1,986 Views
13 Pages

Background: Among rheumatologic diseases following therapy with immune checkpoint inhibitors (ICIs), the cases of cancer patients diagnosed as having polymyalgia rheumatica (PMR), particularly with nivolumab and pembrolizumab, has been steadily risin...

  • Article
  • Open Access
20 Citations
5,770 Views
24 Pages

Enhancing Stability and Performance in Mobile Robot Path Planning with PMR-Dueling DQN Algorithm

  • Demelash Abiye Deguale,
  • Lingli Yu,
  • Melikamu Liyih Sinishaw and
  • Keyi Li

27 February 2024

Path planning for mobile robots in complex circumstances is still a challenging issue. This work introduces an improved deep reinforcement learning strategy for robot navigation that combines dueling architecture, Prioritized Experience Replay, and s...

  • Article
  • Open Access
38 Citations
4,547 Views
9 Pages

11 September 2019

Heteroresistance may pose a threat to the prognosis of patients following colistin treatment. We investigated colistin heteroresistance in Klebsiella pneumoniae isolates from South Korea. Among 252 K. pneumoniae blood isolates, 231 were susceptible t...

  • Article
  • Open Access
4 Citations
1,731 Views
17 Pages

15 December 2023

Lake ice phenology (LIP), hiding information about lake energy and material exchange, serves as an important indicator of climate change. Utilizing an efficient technique to swiftly extract lake ice information is crucial in the field of lake ice res...

  • Article
  • Open Access
263 Views
27 Pages

Objectives: This study presents the development of a bilingual, expert-evaluated question–answer (Q&A) dataset, named PMR-Q&A, designed for training large language models (LLMs) in the field of Physical Medicine and Rehabilitation (PMR)...

  • Brief Report
  • Open Access
3 Citations
2,104 Views
6 Pages

30 May 2023

Background: There is little literature on the paraneoplastic value of the absence of long-lasting morning stiffness (MS) at the time of diagnosis of polymyalgia rheumatica (PMR). We investigated whether and to what extent this finding was related to...

  • Perspective
  • Open Access
4 Citations
3,056 Views
8 Pages

22 February 2022

Background: Glucocorticoids (GCs) are the cornerstone of polymyalgia rheumatica (PMR) therapy, but their long-term use (as is usually necessary in PMR patients) can induce many adverse events. Alternatives have long been sought. The primary aim of ou...

  • Article
  • Open Access
1 Citations
3,909 Views
9 Pages

Morphotypological Prevalence of Individuals Assessed by the Method of Global Postural Reeducation by Proprioceptive and Muscular Rebalancing (GPR/PMR)

  • Nélio Silva de Souza,
  • Renan Ramos Barcellos,
  • Ana Carolina G. Martins,
  • Glória M. M. Vianna da Rosa,
  • Marco A. Araújo Leite,
  • Carla P. Ayres da Silva,
  • Silmar Teixeira and
  • Victor Hugo Bastos

Introduction: Postural control integrates information from the visual, vestibular, and proprioceptive systems, controlling the body position in space. Global Posture Reeducation (GPR) is a clinically well-accepted method that mainly addresses the pro...

  • Technical Note
  • Open Access
4 Citations
1,487 Views
17 Pages

21 March 2025

Fengyun-3G (FY-3G), successfully launched on 16 April 2023, is China’s first and the third in the world satellite dedicated to precipitation measurement. In this study, the reflectivity factors of the FY-3G satellite Precipitation Measurement R...

  • Case Report
  • Open Access
7 Citations
6,715 Views
6 Pages

20 September 2018

The possibility that polymyalgia rheumatica (PMR) can be diagnosed when both ESR and CRP are normal at the time of diagnosis and before therapy with glucocorticoids, has been often discussed in the literature. We present a case report of a 100-year-o...

  • Article
  • Open Access
7 Citations
3,164 Views
12 Pages

Whole-Body [18F]FDG PET/CT Can Alter Diagnosis in Patients with Suspected Rheumatic Disease

  • Matthias Fröhlich,
  • Sebastian Serfling,
  • Takahiro Higuchi,
  • Martin G. Pomper,
  • Steven P. Rowe,
  • Marc Schmalzing,
  • Hans-Peter Tony,
  • Michael Gernert,
  • Patrick-Pascal Strunz and
  • Rudolf A. Werner
  • + 7 authors

9 November 2021

The 2-deoxy-d-[18F]fluoro-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) is widely utilized to assess the vascular and articular inflammatory burden of patients with a suspected diagnosis of rheumatic disease. We aimed to e...

  • Article
  • Open Access
7 Citations
2,187 Views
14 Pages

Association of Platelet-Monocyte Ratio with Dyslipidemia in Saudi Arabia: A Large, Population-Based Study

  • Mohammad A. Alfhili,
  • Ghada A. Alotaibi,
  • Mohammed Alfaifi,
  • Yousef Almoghrabi and
  • Jawaher Alsughayyir

4 August 2023

Background: Abnormal lipid metabolism predisposes to cardiovascular disease. However, dyslipidemia is often asymptomatic leading to its underdiagnosis. Therefore, it is of utmost importance to identify biomarkers that reflect an abnormal lipid profil...

  • Article
  • Open Access
2 Citations
3,020 Views
12 Pages

8 August 2023

Background and Objectives: Limited palatal muscle resection (PMR) is a surgical technique employed to alleviate respiratory disturbances in obstructive sleep apnea (OSA) patients with retropalatal narrowing by reducing soft palate volume and tighteni...

  • Article
  • Open Access
1,682 Views
17 Pages

Landscape of Post-Marketing Requirements Under the Pediatric Research Equity Act for Antibiotics from 2009–2024

  • Daniel Selig,
  • Funmi Aminu,
  • Sue Cammarata,
  • Ting Chen,
  • Lauren Dolak,
  • Stephen Duprez,
  • Stephanie Ecker,
  • Lisa Gault,
  • Sandra George and
  • Doug Girgenti
  • + 4 authors

Background/Objectives: We reviewed Post-Marketing Requirements (PMRs) under the Pediatric Research Equity Act (PREA) for antibiotics approved in adults from 2009 to 2024 to better understand factors associated with PMR study completion. Methods: Init...

  • Article
  • Open Access
14 Citations
4,063 Views
9 Pages

The Effect of Transcutaneous Vagus Nerve Stimulation in Patients with Polymyalgia Rheumatica

  • Jacob Venborg,
  • Anne-Marie Wegeberg,
  • Salome Kristensen,
  • Birgitte Brock,
  • Christina Brock and
  • Mogens Pfeiffer-Jensen

16 November 2021

(1) Polymyalgia rheumatica (PMR) is an inflammatory disease characterised by pain, morning stiffness, and reduced quality of life. Recently, vagus nerve stimulation (VNS) was shown to have anti-inflammatory effects. We aimed to examine the effect of...

  • Article
  • Open Access
13 Citations
2,638 Views
12 Pages

31 December 2021

Melanins are the common fungal pigment, which contribute to stress resistance and pathogenesis. However, few studies have explored the regulation mechanism of its synthesis in filamentous fungi. In this study, we identified two transcription factors,...

  • Article
  • Open Access
16 Citations
4,022 Views
21 Pages

17 September 2022

With the development of maritime technology and equipment, most ships are equipped with an automatic identification system (AIS) to store navigation information. Over time, the size of the data increases, rendering its storage and processing difficul...

  • Article
  • Open Access
14 Citations
2,975 Views
20 Pages

Performance of a Solar-Driven Photocatalytic Membrane Reactor for Municipal Wastewater Treatment

  • Mirela Alina Constantin,
  • Lucian Alexandru Constantin,
  • Ioana Alexandra Ionescu,
  • Cristina Mihaela Nicolescu,
  • Marius Bumbac and
  • Olga Tiron

20 March 2024

The increasing demand for efficient wastewater treatment technologies, driven by global population growth and industrialisation, highlights the necessity for advanced, reliable solutions. This study investigated the efficacy of a slurry photocatalyti...

  • Article
  • Open Access
4 Citations
3,500 Views
8 Pages

30 June 2022

Background: Polymyalgia rheumatica (PMR) is the most common systemic inflammatory rheumatic disease affecting the elderly. Giant cell arteritis (GCA) is a granulomatous vasculitis affecting the aorta and its branches associated with PMR in up to 20%...

  • Review
  • Open Access
11 Citations
16,756 Views
86 Pages

The State of the Art in Post-Mortem Redistribution and Stability of New Psychoactive Substances in Fatal Cases: A Review of the Literature

  • Luis Manuel Menéndez-Quintanal,
  • Jose Manuel Matey,
  • Violeta del Fresno González,
  • Begoña Bravo Serrano,
  • Francisco Javier Hernández-Díaz,
  • Félix Zapata,
  • Gemma Montalvo and
  • Carmen García-Ruiz

4 December 2024

In post-mortem (PM) investigations, forensic toxicologists attempt to identify legal or illegal substances present before death and determine how they contributed to the cause of death. A critical challenge is ensuring that PM sample concentrations a...

  • Article
  • Open Access
10 Citations
3,883 Views
13 Pages

Changes in Brain Energy and Membrane Metabolism in Glioblastoma following Chemoradiation

  • Astrid Ellen Grams,
  • Stephanie Mangesius,
  • Ruth Steiger,
  • Ivan Radovic,
  • Andreas Rietzler,
  • Lisa Maria Walchhofer,
  • Malik Galijašević,
  • Julian Mangesius,
  • Martha Nowosielski and
  • Elke Ruth Gizewski
  • + 2 authors

1 December 2021

Brain parenchyma infiltration with glioblastoma (GB) cannot be entirely visualized by conventional magnetic resonance imaging (MRI). The aim of this study was to investigate changes in the energy and membrane metabolism measured with phosphorous MR s...

  • Article
  • Open Access
15 Citations
12,626 Views
22 Pages

How Therapeutic Tapping Can Alter Neural Correlates of Emotional Prosody Processing in Anxiety

  • Nicola König,
  • Sarah Steber,
  • Josef Seebacher,
  • Quinten von Prittwitz,
  • Harald R. Bliem and
  • Sonja Rossi

19 August 2019

Anxiety disorders are the most common psychological disorders worldwide resulting in a great demand of adequate and cost-effective treatment. New short-term interventions can be used as an effective adjunct or alternative to pharmaco- and psychothera...

  • Feature Paper
  • Article
  • Open Access
1,092 Views
20 Pages

Photocatalytic Mineralization of Emerging Organic Contaminants Using Real and Simulated Effluents in Batch and Membrane Photoreactors

  • Cristina Lavorato,
  • Angela Severino,
  • Pietro Argurio,
  • Raffaele Molinari,
  • Beatrice Russo,
  • Alberto Figoli and
  • Teresa Poerio

18 September 2025

Conventional wastewater treatment plants (WWTPs) have limited efficiency in removing emerging pollutants (EPs), meaning these pollutants persist and lead to widespread ecological contamination. In this study, real effluents from a WWTP were character...

  • Article
  • Open Access
2 Citations
3,084 Views
10 Pages

Colistin Resistance Mechanism in Enterobacter hormaechei subsp. steigerwaltii Isolated from Wild Boar (Sus scrofa) in France

  • Younes Laidoudi,
  • Edgarthe Priscilla Ngaiganam,
  • Jean-Lou Marié,
  • Isabelle Pagnier,
  • Jean-Marc Rolain,
  • Seydina Mouhamadou Diene and
  • Bernard Davoust

7 September 2022

Wild animals may act as efficient antimicrobial-resistance reservoirs and epidemiological links between humans, livestock, and natural environments. By using phenotypic and genotypic characterization, the present study highlighted the occurrence of a...

  • Article
  • Open Access
12 Citations
5,847 Views
16 Pages

Perceived Stress, Salivary Cortisol, and Temperament Traits among Students of Dental Medicine: A Prospective and Interventional Study

  • Bruno Špiljak,
  • Luka Šimunović,
  • Maja Vilibić,
  • Milena Hanžek,
  • Danijel Crnković and
  • Liborija Lugović-Mihić

31 March 2024

Academic stress affects students’ psychological and physiological well-being. Dental undergraduate programs are known for their demanding curriculum, leading to significant stress symptoms. The objective was to determine if salivary cortisol le...

  • Article
  • Open Access
1 Citations
1,703 Views
15 Pages

Evaluation of the Method of Periodic Medium Renewal of Bacillus aryabhattai RAF 5 and Analysis of P(3HB) Production

  • Aidana Rysbek,
  • Urszula Jankiewicz,
  • Ewelina Pogorzelska-Nowicka,
  • Jarosław Wyrwisz,
  • Sailau Abeldenov,
  • Aleksandra M. Mirończuk and
  • Agnieszka Richert

2 April 2025

The purpose of this study was to assess the ability of Bacillus aryabhattai RAF 5 to produce P(3HB) under conditions of periodic medium renewal (PMR). The producer was isolated and confirmed using transmission electron microscopy (TEM), which reveale...

  • Systematic Review
  • Open Access
2 Citations
3,331 Views
13 Pages

19 November 2024

Background: This study aimed to determine the molecular epidemiology of colistin-resistant A. baumannii in the last ten years and the frequency of gene regions related to pathogenesis, to compare the methods used to detect genes, and to confirm colis...

  • Article
  • Open Access
26 Citations
4,502 Views
14 Pages

The Pro-Oxidant Activity of Red Wine Polyphenols Induces an Adaptive Antioxidant Response in Human Erythrocytes

  • Idolo Tedesco,
  • Carmela Spagnuolo,
  • Gian Luigi Russo,
  • Maria Russo,
  • Carmen Cervellera and
  • Stefania Moccia

The protective effect of dealcoholized red wine on human health has been partially associated with its polyphenolic components, suggesting that the pool of polyphenols, including flavonoids and anthocyanins, can be responsible for the functional effe...

  • Article
  • Open Access
8 Citations
4,923 Views
17 Pages

The StkSR Two-Component System Influences Colistin Resistance in Acinetobacter baumannii

  • Sarah K. Giles,
  • Uwe H. Stroeher,
  • Bhavya Papudeshi,
  • Robert A. Edwards,
  • Jessica AP. Carlson-Jones,
  • Michael Roach and
  • Melissa H. Brown

Acinetobacter baumannii is an opportunistic human pathogen responsible for numerous severe nosocomial infections. Genome analysis on the A. baumannii clinical isolate 04117201 revealed the presence of 13 two-component signal transduction systems (TCS...

  • Article
  • Open Access
12 Citations
5,069 Views
16 Pages

With the rapid development of the economy and society, fine particulate matter (PM2.5) has not only caused severe environmental problems, but also posed a threat to public health. In order to improve the estimated accuracy of PM2.5, the input data fi...

  • Article
  • Open Access
31 Citations
4,105 Views
13 Pages

Genomic Characteristics of Colistin-Resistant Salmonella enterica subsp. enterica Serovar Infantis from Poultry Farms in the Republic of Serbia

  • Branko Jovčić,
  • Katarina Novović,
  • Brankica Filipić,
  • Maja Velhner,
  • Dalibor Todorović,
  • Kazimir Matović,
  • Zoran Rašić,
  • Sonja Nikolić,
  • Ferenc Kiškarolj and
  • Milan Kojić

10 December 2020

The antimicrobial susceptibility testing was conducted on 174 single isolates from poultry farms in Serbia and it was determined that seven Salmonella spp. were multidrug resistant. Sixteen serotypes were detected, but only serotype Infantis confirme...

  • Article
  • Open Access
2,388 Views
18 Pages

Study on Thermal Oxygen Aging Characteristics and Degradation Kinetics of PMR350 Resin

  • Yadan Wu,
  • Wenchen Zhao,
  • Yang Liu,
  • Haitao Liu,
  • Minglong Yang and
  • Xun Sun

10 September 2024

The thermal stability and aging kinetics of polyimides have garnered significant research attention. As a newly developed class of high thermal stability polyimide, the thermal aging characteristics and degradation kinetics of phenylene-capped polyim...

  • Article
  • Open Access
11 Citations
3,058 Views
12 Pages

Colistin Resistance Mechanisms in Human and Veterinary Klebsiella pneumoniae Isolates

  • Manuela Tietgen,
  • Lisa Sedlaczek,
  • Paul G. Higgins,
  • Heike Kaspar,
  • Christa Ewers and
  • Stephan Göttig

21 November 2022

Colistin (polymyxin E) is increasingly used as a last-resort antibiotic for the treatment of severe infections with multidrug-resistant Gram-negative bacteria. In contrast to human medicine, colistin is also used in veterinary medicine for metaphylax...

  • Article
  • Open Access
647 Views
18 Pages

PmrA Mutations in Drug-Resistant Acinetobacter baumannii Affect Sensor Kinase-Response Regulator Interaction and Phosphotransfer

  • Felicia E. Jaimes,
  • Alexander D. Hondros,
  • Jude Kinkead,
  • Morgan E. Milton,
  • Richele J. Thompson,
  • Aimee M. Figg,
  • Christian Melander and
  • John Cavanagh

Multi-drug resistance in Acinetobacter baumannii poses a significant human health threat. For multidrug-resistant pathogens, ‘last line of defense’ antibiotics like the polymyxins are implemented. Concerningly, polymyxin-resistance is evi...

  • Article
  • Open Access
305 Views
13 Pages

Development and Characterization of Chitosan-TiO2-Based Photocatalytic Membrane for Water Treatment: Applications on Methylene Blue Elimination

  • Hamza En-nasri,
  • Abdellatif Aarfane,
  • Badreddine Hatimi,
  • Najoua Labjar,
  • Meryem Bensemlali,
  • Abdoullatif Baraket,
  • Mina Bakasse,
  • Nadia Zine,
  • Nicole Jaffrezic-Renault and
  • Hamid Nasrellah
  • + 1 author

13 January 2026

Photocatalytic membrane reactors (PMRs) are an innovative technology for water treatment, effectively combining membrane filtration and photocatalysis to enhance contaminant removal while enabling the regeneration of fouled membranes. In this study,...

  • Article
  • Open Access
6 Citations
3,802 Views
16 Pages

Critical Role of 3′-Downstream Region of pmrB in Polymyxin Resistance in Escherichia coli BL21(DE3)

  • Fuzhou Xu,
  • Atsushi Hinenoya,
  • Ximin Zeng,
  • Xing-Ping Li,
  • Ziqiang Guan and
  • Jun Lin

Polymyxins, such as colistin and polymyxin B, are the drugs used as a last resort to treat multidrug-resistant Gram-negative bacterial infections in humans. Increasing colistin resistance has posed a serious threat to human health, warranting in-dept...

  • Review
  • Open Access
107 Citations
14,714 Views
19 Pages

Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the treatment of infections caused by multidrug-resistant A. baumannii....

  • Article
  • Open Access
170 Views
18 Pages

27 January 2026

In permanent magnet synchronous motor (PMSM) drive systems, the nonlinearity of the inverter and non-sinusoidal nature of back EMF generate harmonics in the stator current, resulting in torque ripple and reduced motor efficiency. Although the proport...

  • Review
  • Open Access
60 Citations
6,769 Views
35 Pages

Critical Issues and Guidelines to Improve the Performance of Photocatalytic Polymeric Membranes

  • Marta Romay,
  • Nazely Diban,
  • Maria J. Rivero,
  • Ane Urtiaga and
  • Inmaculada Ortiz

19 May 2020

Photocatalytic membrane reactors (PMR), with immobilized photocatalysts, play an important role in process intensification strategies; this approach offers a simple solution to the typical catalyst recovery problem of photocatalytic processes and, by...

  • Communication
  • Open Access
11 Citations
2,428 Views
10 Pages

24 June 2022

This paper proposes a novel inverse method based on the deep convolutional neural network (ConvNet) to extract snow’s layer thickness and temperature via passive microwave remote sensing (PMRS). The proposed ConvNet is trained using simulated data ob...

  • Article
  • Open Access
5 Citations
2,888 Views
8 Pages

Emergence of Colistin-Resistant Acinetobacter junii in China

  • Zhiren Wang,
  • Xuanyang Fan,
  • Shuyi Wang,
  • Shuguang Li,
  • Yue Gao,
  • Hui Wang and
  • Henan Li

24 November 2022

The increasing number of multidrug-resistant Gram-negative bacteria presents a serious threat to global health. However, colistin-resistant Acinetobacter junii has rarely been reported. We identified a colistin-resistant A. junii clinical isolate, AJ...

  • Article
  • Open Access
17 Citations
4,945 Views
15 Pages

Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants

  • Alejandro Gallardo,
  • María Ugarte-Ruiz,
  • Marta Hernández,
  • Pedro Miguela-Villoldo,
  • David Rodríguez-Lázaro,
  • Lucas Domínguez and
  • Alberto Quesada

Plasmid-mediated colistin resistance (mcr) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 mcr genes described so far, the major determinants mcr-1 and mcr-3 are found closely linked to hpap2 or dgkA...

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