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46 pages, 1449 KB  
Review
MXenes in Solid-State Batteries: Multifunctional Roles from Electrodes to Electrolytes and Interfacial Engineering
by Francisco Márquez
Batteries 2025, 11(10), 364; https://doi.org/10.3390/batteries11100364 - 2 Oct 2025
Abstract
MXenes, a rapidly emerging family of two-dimensional transition metal carbides and nitrides, have attracted considerable attention in recent years for their potential in next-generation energy storage technologies. In solid-state batteries (SSBs), they combine metallic-level conductivity (>103 S cm−1), adjustable surface [...] Read more.
MXenes, a rapidly emerging family of two-dimensional transition metal carbides and nitrides, have attracted considerable attention in recent years for their potential in next-generation energy storage technologies. In solid-state batteries (SSBs), they combine metallic-level conductivity (>103 S cm−1), adjustable surface terminations, and mechanical resilience, which makes them suitable for diverse functions within the cell architecture. Current studies have shown that MXene-based anodes can deliver reversible lithium storage with Coulombic efficiencies approaching ~98% over 500 cycles, while their use as conductive additives in cathodes significantly improves electron transport and rate capability. As interfacial layers or structural scaffolds, MXenes effectively buffer volume fluctuations and suppress lithium dendrite growth, contributing to extended cycle life. In solid polymer and composite electrolytes, MXene fillers have been reported to increase Li+ conductivity to the 10−3–10−2 S cm−1 range and enhance Li+ transference numbers (up to ~0.76), thereby improving both ionic transport and mechanical stability. Beyond established Ti-based systems, double transition metal MXenes (e.g., Mo2TiC2, Mo2Ti2C3) and hybrid heterostructures offer expanded opportunities for tailoring interfacial chemistry and optimizing energy density. Despite these advances, large-scale deployment remains constrained by high synthesis costs (often exceeding USD 200–400 kg−1 for Ti3C2Tx at lab scale), restacking effects, and stability concerns, highlighting the need for greener etching processes, robust quality control, and integration with existing gigafactory production lines. Addressing these challenges will be crucial for enabling MXene-based SSBs to transition from laboratory prototypes to commercially viable, safe, and high-performance energy storage systems. Beyond summarizing performance, this review elucidates the mechanistic roles of MXenes in SSBs—linking lithiophilicity, field homogenization, and interphase formation to dendrite suppression at Li|SSE interfaces, and termination-assisted salt dissociation, segmental-motion facilitation, and MWS polarization to enhanced electrolyte conductivity—thereby providing a clear design rationale for practical implementation. Full article
(This article belongs to the Collection Feature Papers in Batteries)
15 pages, 1213 KB  
Article
Valorization of Mixed Lignocellulosic Biomass for Bioethanol Production Using Thermotolerant Yeast Saccharomyces cerevisiae SC90
by Malaika Amjad, Muhammad Abbas, Abdullah Langou, Imrana Niaz Sultan and Afrasiab Khan Tareen
Fermentation 2025, 11(10), 565; https://doi.org/10.3390/fermentation11100565 - 30 Sep 2025
Abstract
Bioethanol manifests an extraordinary potential to overcome the severe energy crises and reliance on fossil fuels, yet it supports the sustainable and cost-effective production of fuels for automobile engines and contributes to the reduction of greenhouse gas (GHG) emissions and other global climate-related [...] Read more.
Bioethanol manifests an extraordinary potential to overcome the severe energy crises and reliance on fossil fuels, yet it supports the sustainable and cost-effective production of fuels for automobile engines and contributes to the reduction of greenhouse gas (GHG) emissions and other global climate-related challenges. The present study examines the potential of Mixed Lignocellulosic Biomass (MLB) as a sustainable feedstock for the consistent year-round production of bioethanol. The primary MLB sources considered in this research to underscore the significance of this heterogeneous strategy include sweet sorghum bagasse (SSB), sugarcane bagasse (SCB), and date palm trunk (DPT). Each of the three feedstocks, i.e., SSB, SCB, and DPT, were individually subjected to alkaline pretreatment, a step aimed at breaking down structural barriers and facilitating greater release of fermentable sugars during fermentation. Likewise, the alkaline-pretreated biomasses were subjected to simultaneous saccharification and fermentation (SSF) for 96 h, both individually as well as in various combined proportions. Individually, pretreated sweet sorghum bagasse (SSB) fibers produced the highest ethanol concentration, of 30.79 ± 0.44 g/L; an ethanol yield of 0.40 ± 0.62 g/g; an ethanol productivity of 0.42 ± 0.87 g/L/h; and a theoretical ethanol yield of 79.81% at 72 h. In contrast, the combination of MLB (50% of pretreated SSB and 50% of DPT fibers) produced a significantly higher ethanol concentration of 31.47 ± 0.57 g/L and an ethanol productivity of 0.653 ± 0.24 g/L/h in much less time, i.e., 48 h of SSF fermentation. The empirical data confirms that MLB offers a sustainable paradigm for ethanol biosynthesis by curtailing fermentation time and optimizing economic and operational efficacy. Full article
(This article belongs to the Special Issue Lignocellulosic Biomass Valorisation, 2nd Edition)
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23 pages, 671 KB  
Article
The Impact of the Organization on the Autonomy of Agents
by Zouheyr Tamrabet, Djamel Nessah, Toufik Marir, Varun Gupta and Farid Mokhati
Information 2025, 16(10), 838; https://doi.org/10.3390/info16100838 - 27 Sep 2025
Abstract
In multi-agent systems (MAS), autonomy is a fundamental characteristic that enables agents to operate independently and adaptively within complex environments. However, such characteristics may cause the system to fall into undesirable situations. On the one hand, purely autonomous agents are difficult to predict. [...] Read more.
In multi-agent systems (MAS), autonomy is a fundamental characteristic that enables agents to operate independently and adaptively within complex environments. However, such characteristics may cause the system to fall into undesirable situations. On the one hand, purely autonomous agents are difficult to predict. On the other hand, fully controlled agents lose many of their abilities. Therefore, control frameworks have been designed in the form of organizational architectures to help address the need for balance between purely autonomous and fully controlled agents. This paper investigates the impact of organization on the autonomy of the agents. To measure this impact, we propose a set of seven metrics (Behavioral Wealth (BW), Service Wealth (SW), Frequency of Service Searches per Time (FoSST), Frequency of Service Searches per Behavior (FoSSB), Number of Service Searches (NoSS), Number of Service Demands per Behavior (NoSDB), and Number of Provided Services per Demand (NoPSD)) and apply them to a case study implemented in two configurations: with and without organizational aspects. To model organizational aspects, we adopt the Agent–Group–Role (AGR) model, chosen for its structured approach to defining agent responsibilities and interactions. The findings of this study show that the organizational aspects reduce the communication load and enhance the effectiveness of agents. Full article
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20 pages, 627 KB  
Review
Childhood Obesity and Its Physiological Association with Sugar-Sweetened, Free-Sugar Juice, and Artificially Sweetened Beverages
by Meryem El Ouardi, Guillem Garcia-Llorens and Victoria Valls-Belles
Beverages 2025, 11(5), 137; https://doi.org/10.3390/beverages11050137 - 19 Sep 2025
Viewed by 346
Abstract
Childhood obesity represents a growing global public health crisis, strongly driven by the widespread consumption of sugar-sweetened beverages (SSBs) and, increasingly, artificially sweetened beverages (ASBs). SSB intake drives excessive calorie consumption, reduces satiety, and disrupts hormones, leading to metabolic dysfunction such as insulin [...] Read more.
Childhood obesity represents a growing global public health crisis, strongly driven by the widespread consumption of sugar-sweetened beverages (SSBs) and, increasingly, artificially sweetened beverages (ASBs). SSB intake drives excessive calorie consumption, reduces satiety, and disrupts hormones, leading to metabolic dysfunction such as insulin resistance and type 2 diabetes. Despite some regional declines, global consumption of SSBs remains high, with persistent socioeconomic disparities. Concurrently, ASBs, marketed as healthier alternatives, pose emerging metabolic and behavioral risks, such as gut microbiota disruption and altered appetite regulation, raising concerns about their long-term safety. Both beverage types displace nutritionally balanced food options in children’s diets and foster enduring preferences for sweetness, exacerbating poor dietary quality. Public health interventions targeting SSB reduction have demonstrated modest success; however, rising ASB use complicates prevention strategies. Effective mitigation of childhood obesity requires comprehensive approaches that emphasize reducing all sweetened beverage consumption, promoting water and whole-food hydration, and addressing the behavioral and environmental factors underlying unhealthy beverage choices to improve lifelong health outcomes. Full article
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17 pages, 1718 KB  
Article
A Fifth-Generation-Based Synchronized Measurement Method for Urban Distribution Networks
by Jie Zhang, Bo Pang, Linghao Zhang and Sihao Tang
Energies 2025, 18(17), 4767; https://doi.org/10.3390/en18174767 - 8 Sep 2025
Viewed by 503
Abstract
This work proposes a 5G-based synchronized measurement method for urban distribution networks. First, downlink frequency synchronization is achieved by cross-correlating the Primary and Secondary Synchronization Signals (PSSs/SSSs) within gNB-broadcast Synchronization Signal Blocks (SSBs), enabling accurate alignment with the 5G system clock. Then, uplink [...] Read more.
This work proposes a 5G-based synchronized measurement method for urban distribution networks. First, downlink frequency synchronization is achieved by cross-correlating the Primary and Secondary Synchronization Signals (PSSs/SSSs) within gNB-broadcast Synchronization Signal Blocks (SSBs), enabling accurate alignment with the 5G system clock. Then, uplink phase synchronization is refined using Timing Advance (TA) feedback to compensate for propagation delays. Based on the recovered 5G Pulse Per Second (PPS) signal, a dynamic compensation algorithm is applied to discipline the SAR ADC sampling process. This algorithm tracks crystal oscillator drift, accumulates sub-cycle deviations, and corrects integer timer counts only when the error exceeds ±0.5. Simulations under a 228 MHz oscillator and 1200 samples per cycle demonstrate that the accumulated phase error remains below 0.00008°, satisfying IEEE C37.118 precision requirements. Compared with traditional GPS-based synchronization methods, the proposed solution offers greater deployment flexibility and can operate reliably in GPS-denied environments such as indoors and urban canyons. Full article
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17 pages, 472 KB  
Article
Associations of TAS1R2 and TAS2R38 Genetic Variants with Sugar-Sweetened Beverage Intake and Obesity Risk in Kuwaiti Adolescents: A Cross-Sectional Study
by Razan Yousef, Dalal Usamah Zaid Alkazemi, Mohamed Abu-Farha, Jehad Abubaker, Sriraman Devarajan, Abdur Rahman and Fahd Al-Mulla
Children 2025, 12(9), 1192; https://doi.org/10.3390/children12091192 - 8 Sep 2025
Viewed by 611
Abstract
Background/Objectives: Obesity is increasing worldwide, driven by unhealthy dietary habits and sedentary lifestyles. Genetic variations in taste receptor genes, particularly TAS1R2 and TAS2R38, may influence taste preferences, dietary intake, and obesity risk. This study examined associations between TAS1R2 and TAS2R38 polymorphisms, [...] Read more.
Background/Objectives: Obesity is increasing worldwide, driven by unhealthy dietary habits and sedentary lifestyles. Genetic variations in taste receptor genes, particularly TAS1R2 and TAS2R38, may influence taste preferences, dietary intake, and obesity risk. This study examined associations between TAS1R2 and TAS2R38 polymorphisms, sugar-sweetened beverage (SSB) intake, and obesity risk in Kuwaiti adolescents. Methods: A cross-sectional study was conducted among 260 adolescents aged 11–14 years recruited from public schools in Kuwait. Genotyping of five single-nucleotide polymorphisms (SNPs) was performed using TaqMan assays. Associations between SNPs, SSB intake, and obesity parameters were evaluated using multinomial logistic regression and non-parametric tests, adjusted for age, sex, nationality, BMI z-scores, basal metabolic rate, and physical activity. p-values were corrected using the Benjamini–Hochberg method. Results: The rs713598 SNP in TAS2R38 showed a marginal association with BMI percentiles and z-scores. Adolescents carrying the CC genotype of rs10246939 SNP in TAS2R38 had significantly lower odds of high SSB consumption (>3 servings/week) compared with T-allele carriers (p = 0.018, OR= 0.24, 95% CI = 0.08–0.79). No significant associations were detected for TAS1R2 SNPs. Conclusions: Variations in TAS2R38 were linked to obesity measures and beverage intake in Kuwaiti adolescents, supporting a potential genetic contribution to dietary behaviors. These findings highlight the importance of taste receptor genetics in obesity research, though replication in larger and more diverse populations is required. Full article
(This article belongs to the Section Pediatric Gastroenterology and Nutrition)
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22 pages, 2142 KB  
Article
Microplastic Distribution in a Small-Scale Aquatic System with Limited Anthropogenic Influence: A Case Study in Sasebo City, Japan
by Huiho Jeong, Daigo Fukuda, Ahmed Elwaleed, Quynh Thi Nguyen, Pyae Sone Soe, Byeong Kyu Min, Hyeon Seo Cho, Tetsuro Agusa and Yasuhiro Ishibashi
Microplastics 2025, 4(3), 55; https://doi.org/10.3390/microplastics4030055 - 26 Aug 2025
Viewed by 885
Abstract
This study presents the first investigation into the distribution of microplastics (MPs) in Sasebo City, Japan, using principal component analysis (PCA) in conjunction with water flow velocity and salinity variables. The mean MP abundance was 82.4 ± 47.7 items/m3 (SSB1–SSB4), showing no [...] Read more.
This study presents the first investigation into the distribution of microplastics (MPs) in Sasebo City, Japan, using principal component analysis (PCA) in conjunction with water flow velocity and salinity variables. The mean MP abundance was 82.4 ± 47.7 items/m3 (SSB1–SSB4), showing no significant difference among sampling points. The fragment-to-fiber ratio was 76:24, and polypropylene and polyethylene (each 41%) were the main polymers. Fragment abundance increased with decreasing particle size, while fibers were rare below 700 μm. PCA indicated distinct MP polymer and shape distributions corresponding to stagnant water (SSB1), high-flow conditions (SSB2 and SSB3), and seawater (SSB4). Based on the literature, the study area represents a case of a small-scale aquatic system with limited anthropogenic influence due to moderate population, short river length, efficient effluent discharge, minimal industry, good water quality, and the absence of significant spatial variation in MP abundance. The infrequent precipitation during the sampling event supports the findings of the present study as a reliable baseline for objectively assessing MP contamination. Compared to aquatic systems of varying scales and anthropogenic influence, this baseline is applicable to both small-scale and large-scale aquatic systems with significant influences. This will serve as a valuable reference for future MP studies across diverse freshwater environments. Full article
(This article belongs to the Collection Feature Papers in Microplastics)
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21 pages, 3132 KB  
Article
Molecular Characterization and Protective Efficacy of a Novel Protein (EnSSB) Containing a Single-Stranded DNA-Binding Domain from Eimeria necatrix
by Yu Zhu, Dandan Liu, Lele Wang, Qianqian Feng, Nianyu Xue, Zhaofeng Hou, Jinjun Xu and Jianping Tao
Animals 2025, 15(17), 2482; https://doi.org/10.3390/ani15172482 - 23 Aug 2025
Viewed by 412
Abstract
SSB proteins play essential roles in DNA replication, recombination, and repair in bacteria, archaea, and eukarya. This study investigates the transcript levels, identification, expression and purification, subcellular localization, and immune protective potential of the SSB-like proteins of Eimeria necatrix (EnSSB), exploring its role [...] Read more.
SSB proteins play essential roles in DNA replication, recombination, and repair in bacteria, archaea, and eukarya. This study investigates the transcript levels, identification, expression and purification, subcellular localization, and immune protective potential of the SSB-like proteins of Eimeria necatrix (EnSSB), exploring its role in the development of E. necatrix and its potential as a candidate antigen for a subunit vaccine against avian coccidiosis. The level of EnSSB gene transcription was highest in unsporulated oocysts (UO), followed by gametocytes (GAM) (p < 0.05). The gene consisted of an open reading frame of 1488 nucleotides encoding a protein of 495 amino acid residues with a predicted molecular weight of 53.31 kDa. EnSSB contained a SSB domain with a conserved OB (oligonucleotide/oligosaccharide binding) fold. The molecular mass of the native protein, as determined by Western blot analysis, was ~58 kDa in second-generation merozoites (MZ-2) and UO. In addition to the 58 kDa band, four other bands (~98 kDa, ~82 kDa, ~36 kDa and ~28 kDa) were detected in GAM. No bands were detected in MZ-3. Indirect immunofluorescence and immuno-electron microscopy localized EnSSB in the cytoplasm of macrogametocytes but not in wall-forming bodies and oocyst wall. Animal challenge experiments demonstrated that rEnSSB elicited robust IgY responses, increased splenic T lymphocytes and body weight gain, reduced intestinal lesion scores and oocyst shedding, and presented anticoccidial index (ACI) more than 160. These findings not only offer a foundation for understanding the role of EnSSB protein in regulating the development of E. necatrix, but also present a potential protective antigen of E. necatrix for the development of a subunit vaccine against avian coccidiosis. Full article
(This article belongs to the Special Issue Coccidian Parasites: Epidemiology, Control and Prevention Strategies)
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16 pages, 2255 KB  
Article
Consumption of 100% Juice and Diluted 100% Juice Is Associated with Better Compliance with Dietary Guidelines for Americans: Analyses of NHANES 2017–2023
by Rozenn Gazan, Matthieu Maillot and Adam Drewnowski
Nutrients 2025, 17(16), 2715; https://doi.org/10.3390/nu17162715 - 21 Aug 2025
Viewed by 1485
Abstract
Background: The Dietary Guidelines for Americans (DGA) and the American Academy of Pediatrics recommend limiting 100% juice consumption to 0.5–1.25 cups/day and to no more than one half of total fruit intake. Objective: To explore the dietary benefits of consuming 100% [...] Read more.
Background: The Dietary Guidelines for Americans (DGA) and the American Academy of Pediatrics recommend limiting 100% juice consumption to 0.5–1.25 cups/day and to no more than one half of total fruit intake. Objective: To explore the dietary benefits of consuming 100% fruit juice and diluted 100% juice across diverse socio-demographic strata in the US. Methods: Consumption patterns for 100% juice and diluted 100% juice were examined by sex, age group, income-to-poverty ratio (IPR), and race/ethnicity. Dietary intakes came from the National Health and Nutrition Examination Survey (NHANES 2017–2020 and 2021–2023). The Healthy Eating Index 2020 (HEI 2020) and diet-level Nutrient Rich Food (NRF9.3) scores were the two measures of diet quality. The amounts of 100% juice consumed were compared to published DGA recommendations. Results: The consumption of 100% juice was greatly below that of water, milk, and sugar-sweetened beverages (SSBs). The consumption of diluted 100% juice was very low. Consumers of 100% juice had higher HEI 2020 scores (53 vs. 48) and diets with less added sugar and more total fruit, more potassium, calcium, and vitamin C. About 88% of the NHANES sample consumed <4 oz/day (1/2 cup) of 100% juice and most derived at least 50% of fruit from whole fruit, though some variation by income and race/ethnicity was observed. About 93% of the sample consumed <1 cup/day (8 oz) of 100% juice. Lower income groups consumed less whole fruit and more 100% juice. Conclusion: The consumption of 100% fruit juice was a marker of healthier dietary choices. The observed social gradient suggests that 100% fruit juice may provide valuable nutrients to populations who may be unable to afford or access whole fruit. Public health recommendations: The consumption of 100% fruit juice by some population subgroups could be increased. Fruit juice was not displacing whole fruit, and current consumption was well below the current DGA recommended values. Full article
(This article belongs to the Section Nutritional Epidemiology)
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17 pages, 375 KB  
Article
The Moderating Role of SSB Conflicts of Interest and Audit Committee Independence in Good Corporate Governance and Islamic Bank Performance in Indonesia
by Jerry Marmen Simanjuntak, Faizi Faizi and Airlangga Surya Kusuma
J. Risk Financial Manag. 2025, 18(8), 466; https://doi.org/10.3390/jrfm18080466 - 21 Aug 2025
Viewed by 604
Abstract
The Sharia Supervisory Board (SSB) and the Audit Committee (AC) are crucial components of Good Corporate Governance (GCG) in Islamic banks. This study investigates the moderating role of SSB conflicts of interest arising from cross-membership in various Islamic Financial Institutions (IFIs) and AC [...] Read more.
The Sharia Supervisory Board (SSB) and the Audit Committee (AC) are crucial components of Good Corporate Governance (GCG) in Islamic banks. This study investigates the moderating role of SSB conflicts of interest arising from cross-membership in various Islamic Financial Institutions (IFIs) and AC members’ independence in the relationship between GCG and Islamic bank performance in Indonesia. Using a sample of ten full-fledged Islamic banks from 2014 to 2023, a Moderated Regression Analysis (MRA) was employed to test three hypotheses. The key findings indicate a significant positive relationship between GCG and Islamic bank financial performance. However, no significant moderating effects of SSB conflicts of interest on the GCG–performance relationship were found. Conversely, a significant positive moderating effect of AC independence was identified. These results have important implications for practitioners, regulators, and stakeholders of the Islamic banking industry. Islamic banks should prioritize the establishment of independent audit committees to strengthen their governance framework. While SSB cross-membership may not necessarily harm performance, banks should implement appropriate oversight mechanisms to manage potential conflicts of interest. The Indonesian Financial Services Authority (OJK) and similar regulatory bodies should continue to emphasize the importance of audit committee independence in their governance guidelines. Full article
(This article belongs to the Section Banking and Finance)
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17 pages, 716 KB  
Article
Examining the Sustainable Impact of the Relationship Among the Variables Influencing Sugar-Sweetened Beverage Intake on Sugar Tax
by Rawlings Obenembot Enowkenwa, Saratiel Wedzarai Musvoto and Fortune Ganda
Sustainability 2025, 17(16), 7474; https://doi.org/10.3390/su17167474 - 19 Aug 2025
Viewed by 706
Abstract
Sugar-sweetened beverages (SSBs) are among the most traded and a significant component of global food and beverages. The consumption of these beverages is widely believed to be a major contributing factor to overweight, diabetes, tooth decay, and other noncommunicable diseases. To reduce the [...] Read more.
Sugar-sweetened beverages (SSBs) are among the most traded and a significant component of global food and beverages. The consumption of these beverages is widely believed to be a major contributing factor to overweight, diabetes, tooth decay, and other noncommunicable diseases. To reduce the intake of these beverages, the World Health Organisation (WHO) encouraged countries and jurisdictions to introduce a sugar tax policy as an approach to reduce the sales and intake of the beverages. The purpose of this study is to evaluate the sustainability of the relationship that exists among the factors that influence the intake of SSBs in enhancing sugar tax in South Africa. A mixed research methods were used to explore the relationships among the variables. The Exploratory Sequential Design (ESD) was deemed appropriate to deal with the introduction of a sugar tax to reduce the intake of the SSB, most especially in Africa where the tax is a new concept. The Exploratory Sequential Design began with the collection of the structured interview qualitative data and analysis using the thematic analysis procedure, then followed by quantitative data collection and analysis using the confirmatory factor analysis method. This study used mainly primary data collected from the Gauteng Province of South Africa for both the qualitative and quantitative phases of the study. The study found that a sustainable effective sugar tax can be achieved when the public is aware of the existence, purpose, and acceptance of the sugar tax. Furthermore, the tax can become relevant and sustainable when it leads to a significant reduction in intake, contributing to negative consumer behaviour and attitude towards the intake of SSBs in South Africa. A synthesis of the integrated results confirmed that the recognition of the relationship among the factors influencing the intake of SSB and penalising the beverage manufacturers who do not reduce the sugar content in all their beverages as recommended by the WHO are vital in leading to a sustainable enhancement of an effective sugar tax in South Africa. Full article
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16 pages, 651 KB  
Article
Association Between the Consumption of Sugar-Sweetened Beverages and High-Caffeine Drinks and Self-Reported Mental Health Conditions Among Korean Adolescents
by Seung Jae Lee, Yeseul Na and Kyung Won Lee
Nutrients 2025, 17(16), 2652; https://doi.org/10.3390/nu17162652 - 15 Aug 2025
Viewed by 1976
Abstract
Background/Objectives: The rising prevalence of mental health disorders among adolescents underscores the need for early intervention. Of concern is the increasing consumption of sugar-sweetened beverages (SSBs) and high-caffeine drinks, which may adversely affect adolescent mental health. This study examined their association with [...] Read more.
Background/Objectives: The rising prevalence of mental health disorders among adolescents underscores the need for early intervention. Of concern is the increasing consumption of sugar-sweetened beverages (SSBs) and high-caffeine drinks, which may adversely affect adolescent mental health. This study examined their association with stress perception, depressive symptoms, suicidal ideation, and loneliness among Korean adolescents. Methods: Data were derived from the 2022 Korea Youth Risk Behavior Survey, a nationally representative dataset comprising 51,850 Korean adolescents aged 12–18 years. Beverage consumption frequency was categorized into three groups: none, 1–4 times per week, and ≥5–6 times per week. Logistic regression models were employed to estimate adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for mental health conditions, adjusting for potential confounders. Results: Compared with non-consumers, adolescents who consumed SSBs ≥5–6 times per week exhibited significantly higher odds of stress perception (AOR 1.35, 95% CI 1.24–1.46), depressive symptoms (AOR 1.32, 95% CI 1.19–1.46), suicidal ideation (AOR 1.23, 95% CI 1.09–1.39), and loneliness (AOR 1.44, 95% CI 1.28–1.61). Similarly, frequent consumption of high-caffeine drinks (≥5–6 times per week) was associated with increased odds of stress perception (AOR 2.13, 95% CI 1.99–2.29), depressive symptoms (AOR 1.75, 95% CI 1.62–1.88), suicidal ideation (AOR 2.04, 95% CI 1.86–2.24), and loneliness (AOR 1.72, 95% CI 1.59–1.87). Conclusions: Frequent consumption of SSBs and high-caffeine drinks is significantly associated with adverse mental health outcomes among Korean adolescents. Given the increasing intake of these beverages, targeted public health interventions are warranted to mitigate their potential negative impact on adolescent mental well-being. Full article
(This article belongs to the Special Issue The Interdependence of Nutrition and Mental Well-Being)
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14 pages, 1405 KB  
Article
A Single DNA Binding Site of DprA Dimer Is Required to Facilitate RecA Filament Nucleation
by Irina Bakhlanova, Begoña Carrasco, Aleksandr Alekseev, Maria Yakunina, Natalia Morozova, Mikhail Khodorkovskii, Michael Petukhov and Dmitry Baitin
Int. J. Mol. Sci. 2025, 26(16), 7873; https://doi.org/10.3390/ijms26167873 - 15 Aug 2025
Viewed by 515
Abstract
DprA (also known as Smf) is a conserved RecA mediator originally characterized by its role in natural chromosomal transformation, yet its widespread presence across bacteria hints at broader DNA metabolic functions. Here, we demonstrate that Bacillus subtilis DprA enhances the frequency of Escherichia [...] Read more.
DprA (also known as Smf) is a conserved RecA mediator originally characterized by its role in natural chromosomal transformation, yet its widespread presence across bacteria hints at broader DNA metabolic functions. Here, we demonstrate that Bacillus subtilis DprA enhances the frequency of Escherichia coli Hfr conjugation in vivo. In vitro, RecA·ATP binds and cooperatively polymerizes in a 50-nucleotide (nt) polydeoxy T (dT)50 ssDNA to form dynamic filaments that SSB inhibits, an effect fully reversed by Bacillus subtilis DprA. Escherichia coli RecA bound to (dT)21 exhibits minimal dATPase activity, but the addition of B. subtilis DprA significantly stimulates RecA dATP hydrolysis. B. subtilis RecA·dATP readily assembles on (dT)20 complexes, and DprA allosterically activates RecA on even shorter (dT)15 substrates. Combining biochemical assays with a fully atomic model of the RecA–DprA–ssDNA complex, we proposed that only one DNA binding site of the DprA dimer engages the ssDNA during RecA loading, owing to steric constraints. This work refines the mechanism of DprA-mediated RecA nucleation and defines the minimal ssDNA footprint required for mediator activity. Full article
(This article belongs to the Section Molecular Biology)
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16 pages, 1707 KB  
Article
An Overview of Analog and Digital RF Generator Techniques, Suitable for Space-Based AOTF Applications
by Jurgen Vanhamel
Appl. Sci. 2025, 15(15), 8739; https://doi.org/10.3390/app15158739 - 7 Aug 2025
Viewed by 490
Abstract
The use of Acousto-Optical Tunable Filters (AOTFs) is well known in ground- and space-based applications. These devices are used in several optical instruments and payloads for monitoring and other purposes. To make use of the filter capability of the AOTF, a dedicated Radio [...] Read more.
The use of Acousto-Optical Tunable Filters (AOTFs) is well known in ground- and space-based applications. These devices are used in several optical instruments and payloads for monitoring and other purposes. To make use of the filter capability of the AOTF, a dedicated Radio Frequency (RF) chain, consisting of an RF generator and RF amplifier, is needed. An RF generator can be designed in several ways. However, the design of these steering devices for space applications comes with several difficulties and limitations. The mechanical stress due to shock and vibration, the temperature variation, as well as the vacuum environment and radiation levels in which these devices have to perform limits the selection of possible techniques. This paper aims at giving an in-depth overview of space-qualified RF generator techniques using Commercial-Off-The-Shelf available components that usable in the harsh environment of space and applicable in driving AOTFs. Several analog as well as digital generator principles are discussed, substantiated by test results. Full article
(This article belongs to the Special Issue Recent Advances in Space Instruments and Sensing Technology)
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19 pages, 2474 KB  
Article
Unraveling the Role of Aluminum in Boosting Lithium-Ionic Conductivity of LLZO
by Md Mozammal Raju, Yi Ding and Qifeng Zhang
Electrochem 2025, 6(3), 29; https://doi.org/10.3390/electrochem6030029 - 4 Aug 2025
Viewed by 1056
Abstract
The development of high-performance solid electrolytes is critical to advancing solid-state lithium-ion batteries (SSBs), with lithium lanthanum zirconium oxide (LLZO) emerging as a leading candidate due to its chemical stability and wide electrochemical window. In this study, we systematically investigated the effects of [...] Read more.
The development of high-performance solid electrolytes is critical to advancing solid-state lithium-ion batteries (SSBs), with lithium lanthanum zirconium oxide (LLZO) emerging as a leading candidate due to its chemical stability and wide electrochemical window. In this study, we systematically investigated the effects of cation dopants, including aluminum (Al3+), tantalum (Ta5+), gallium (Ga3+), and rubidium (Rb+), on the structural, electronic, and ionic transport properties of LLZO using density functional theory (DFT) and ab initio molecular dynamics (AIMD) simulations. It appeared that, among all simulated results, Al-LLZO exhibits the highest ionic conductivity of 1.439 × 10−2 S/cm with reduced activation energy of 0.138 eV, driven by enhanced lithium vacancy concentrations and preserved cubic-phase stability. Ta-LLZO follows, with a conductivity of 7.12 × 10−3 S/cm, while Ga-LLZO and Rb-LLZO provide moderate conductivity of 3.73 × 10−3 S/cm and 3.32 × 10−3 S/cm, respectively. Charge density analysis reveals that Al and Ta dopants facilitate smoother lithium-ion migration by minimizing electrostatic barriers. Furthermore, Al-LLZO demonstrates low electronic conductivity (1.72 × 10−8 S/cm) and favorable binding energy, mitigating dendrite formation risks. Comparative evaluations of radial distribution functions (RDFs) and XRD patterns confirm the structural integrity of doped systems. Overall, Al emerges as the most effective and economically viable dopant, optimizing LLZO for scalable, durable, and high-conductivity solid-state batteries. Full article
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