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29 pages, 3223 KB  
Article
Optimization of Prefabricated Building Component Distribution Under Dynamic Charging Strategy for Electric Heavy-Duty Trucks
by Xinran Qi, Weichen Zheng, Heping Wang and Fuyu Wang
World Electr. Veh. J. 2025, 16(9), 509; https://doi.org/10.3390/wevj16090509 (registering DOI) - 10 Sep 2025
Abstract
To align with the adoption of electric vehicles in the transportation sector, this paper proposes the use of electric heavy-duty trucks for the logistics and distribution of large prefabricated building components. This approach aims to address the problems of high total costs and [...] Read more.
To align with the adoption of electric vehicles in the transportation sector, this paper proposes the use of electric heavy-duty trucks for the logistics and distribution of large prefabricated building components. This approach aims to address the problems of high total costs and significant energy waste in prefabricated component transportation. Focusing on the multi-to-multi distribution mode, a two-level optimization model is constructed. The upper-level model is responsible for the reasonable allocation of demand points. The lower-level model optimizes the selection of road network nodes and charging stations along the delivery routes. It also dynamically adjusts charging timing and volume according to the real-time power situation. To enhance solution performance, a two-level multi-objective evolutionary algorithm based on Pareto theory is designed. This algorithm simultaneously optimizes distribution costs while coordinating path planning and charging strategies. Comparative experiments across different cases show that, compared with traditional single-level and multi-stage models, the proposed algorithm improves both solution accuracy and quality. Additionally, when compared with the scheduling scheme based on the full-charge capacity strategy, the dynamic charging strategy proposed in this paper reduces the total distribution cost by approximately 15.83%. These findings demonstrate that the constructed model and algorithm can effectively optimize the logistics and distribution of prefabricated components. They also provide a feasible solution for the practical application of electric vehicles in engineering logistics. Full article
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21 pages, 1524 KB  
Article
Further Results on the Mathematical Theory of Motion of Researchers Between Research Organizations
by Pavlina Atanasova, Valentin Georgiev, Magdalena Veselinova and Nikolay Vitanov
Mathematics 2025, 13(18), 2930; https://doi.org/10.3390/math13182930 (registering DOI) - 10 Sep 2025
Abstract
Recently, Vitanov and Dimitrova presented a mathematical theory of motion of researchers between research organizations. They obtained analytical results based on exact solutions for a specific case of a model system of ordinary differential equations for studying a system of research organizations. In [...] Read more.
Recently, Vitanov and Dimitrova presented a mathematical theory of motion of researchers between research organizations. They obtained analytical results based on exact solutions for a specific case of a model system of ordinary differential equations for studying a system of research organizations. In this article, we investigate the system of model equations of Vitanov and Dimitrova analytically and numerically, obtaining several new results. We provide sufficient conditions for the concavity of the solutions of the system and make a comparison with an exact solution. We numerically examine the effect of several parameters on the concavity. We further inspect the influence of the parameters on whether the solution has overall increased or decreased compared with the initial condition. Full article
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14 pages, 7190 KB  
Article
Chaos Prediction and Nonlinear Dynamic Analysis of a Dimple-Equipped Electrostatically Excited Microbeam
by Ayman M. Alneamy
Mathematics 2025, 13(18), 2925; https://doi.org/10.3390/math13182925 - 10 Sep 2025
Abstract
As MEMS design encounters growing challenges, particularly stiction between movable and stationary electrodes, dielectric charging, pull-in instability, and multi-valued response characteristics, the integration of dimple-equipped structures has emerged as a pivotal solution to mitigate these fundamental issues. Consequently, this study investigates the dynamic [...] Read more.
As MEMS design encounters growing challenges, particularly stiction between movable and stationary electrodes, dielectric charging, pull-in instability, and multi-valued response characteristics, the integration of dimple-equipped structures has emerged as a pivotal solution to mitigate these fundamental issues. Consequently, this study investigates the dynamic behavior of an electrostatically actuated double-clamped microbeam incorporating dimples and contact pads. While the dimples enhance the beam’s travel range, they may also induce an impact mode upon contact with the landing pads, leading to complex nonlinear dynamic phenomena. A reduced-order model was developed to numerically solve the governing equation of motion. The microbeam’s response was analyzed both with and without dimples using multiple analytical techniques, including bifurcation diagrams and discrete excitation procedures near the impacting regime. The findings demonstrate that the inclusion of dimples effectively suppresses stiction, pull-in instability, and multi-valued responses. The results indicate that upon contacting the landing pads, the beam exhibits pronounced nonlinear dynamic behaviors, manifesting as higher-period oscillations such as period-3, period-4 and period-5 and then fully developed chaotic attractors. Indeed, this specifically demonstrates the potential of using the dynamic transition from a steady-state to a chaotic response to build novel MEMS sensors. Full article
(This article belongs to the Special Issue Advances in Nonlinear Analysis: Theory, Methods and Applications)
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20 pages, 860 KB  
Article
A Life Cycle Assessment Framework for Evaluating the Climate Impact of Hydrogen-Based Passenger Vehicle Technologies Toward Sustainable Mobility
by Péter Németh, Botond Mecséri and Barna Hanula
Hydrogen 2025, 6(3), 68; https://doi.org/10.3390/hydrogen6030068 - 10 Sep 2025
Abstract
Hydrogen-based mobility solutions could offer viable technology for sustainable transportation. Current research often examines single pathways, leaving broader comparisons unexplored. This comparative life cycle assessment (LCA) evaluates which vehicle type achieves the best environmental performance when using hydrogen from grey, blue, and green [...] Read more.
Hydrogen-based mobility solutions could offer viable technology for sustainable transportation. Current research often examines single pathways, leaving broader comparisons unexplored. This comparative life cycle assessment (LCA) evaluates which vehicle type achieves the best environmental performance when using hydrogen from grey, blue, and green production pathways, the three dominant carbon-intensity variants currently deployed. This study examines seven distinct vehicle configurations that rely on hydrogen-derived energy sources across various propulsion systems: a hydrogen fuel cell electric vehicle (H2FCEV), hydrogen internal combustion engine vehicle (H2ICEV), methanol flexible fuel vehicle (MeOH FFV), ethanol flexible vehicle (EtOH FFV), Fischer-Tropsch (FT) diesel internal combustion vehicle (FTD ICEV) and renewable compressed natural gas vehicle (RNGV). Via both grey and blue hydrogen production, H2 FCEVs are the best options from the viewpoint of GWP, but surprisingly, in the green category, FT-fueled vehicles take over both first and second place, as they produce nearly half the lifetime carbon emissions of purely hydrogen-fueled vehicles. RNGV also emerges as a promising alternative, offering optimal engine properties in a system similar to H2ICEVs, enabling parallel development and technological upgrades. These findings not only highlight viable low-carbon pathways but also provide clear guidance for future targeted, detailed, applied research. Full article
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17 pages, 509 KB  
Review
Decision Support Systems in Integrated Pest and Disease Management: Innovative Elements in Sustainable Agriculture
by Anna Tratwal, Magdalena Jakubowska and Aleksandra Pietrusińska-Radzio
Sustainability 2025, 17(18), 8111; https://doi.org/10.3390/su17188111 - 9 Sep 2025
Abstract
Integrated Pest Management (IPM) is a system that combines ready-made plant protection methods. IPM guidelines apply to all users of plant protection products and require the prioritization of preventative methods. Adherence to IPM principles contributes to the production of healthy and safe food. [...] Read more.
Integrated Pest Management (IPM) is a system that combines ready-made plant protection methods. IPM guidelines apply to all users of plant protection products and require the prioritization of preventative methods. Adherence to IPM principles contributes to the production of healthy and safe food. In Poland, the implementation of IPM into agricultural practice remains a solution to the problem. Furthermore, it is necessary to ensure education and implementation of IPM at the basic or implementation level. The IPM element, particularly emphasized in the 2009/128/EC Directive, is the use of so-called warning systems, tools that address the issue of plant protection application. In this regard, it is necessary to use decision support systems (DSSs). DSSs are digital solutions that integrate meteorological, global, and field data. They include the risk of disease and pest occurrence and the timing of the application. DSSs are not part of the farmer’s experience or presentation but support them in making sound decisions. DSS reduces costs, the side effects of plant protection, and energy consumption. Examples of such solutions in Poland include the eDWIN platform and OPWS, classified, among others, in cereal protection against fungi. The aim of this article is to present the role, capabilities, and limitations of decision support systems in modern agricultural production and their importance in the context of the Green Deal and digital agriculture. Full article
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18 pages, 6073 KB  
Article
Harnessing Polyaminal Porous Networks for Sustainable Environmental Applications Using Ultrafine Silver Nanoparticles
by Bedour Almalki, Maymounah A. Alrayyani, Effat A. Bahaidarah, Maha M. Alotaibi, Shaista Taimur, Dalal Alezi, Fatmah M. Alshareef and Nazeeha S. Alkayal
Polymers 2025, 17(18), 2443; https://doi.org/10.3390/polym17182443 - 9 Sep 2025
Abstract
Environmental contamination is a critical global concern, primarily due to detrimental greenhouse gas (GHG) emissions, especially carbon dioxide (CO2), which significantly contribute to climate change. Moreover, the presence of harmful heavy metals like Ni, Cd, Cu, Hg, and Pb in soil [...] Read more.
Environmental contamination is a critical global concern, primarily due to detrimental greenhouse gas (GHG) emissions, especially carbon dioxide (CO2), which significantly contribute to climate change. Moreover, the presence of harmful heavy metals like Ni, Cd, Cu, Hg, and Pb in soil and water ecosystems has led to poor water quality. Noble metal nanoparticles (MNPs), for instance, Pd, Ag, Pt, and Au, have emerged as promising solutions for addressing environmental pollution. However, the practical utilization of MNPs faces challenges as they tend to aggregate and lose stability. To overcome this issue, the reverse double-solvent method (RDSM) was utilized to synthesis melamine-based porous polyaminals (POPs) as a supportive material for the in situ growing of silver nanoparticles (Ag NPs). The porous structure of melamine-based porous polyaminals, featuring aminal-linked (-HN-C-NH-) and triazine groups, provides excellent binding sites for capturing Ag+ ions, thereby improving the dispersion and stability of the nanoparticles. The resulting material exhibited ultrafine particle sizes for Ag NPs, and the incorporation of Ag NPs within the porous polyaminals demonstrated a high surface area (~279 m2/g) and total pore volume (1.21 cm3/g), encompassing micropores and mesopores. Additionally, the Ag NPs@POPs showcased significant capacity for CO2 capture (2.99 mmol/g at 273 K and 1 bar) and effectively removed Cu (II), with a remarkable removal efficiency of 99.04%. The nitrogen-rich porous polyaminals offer promising prospects for immobilizing and encapsulating Ag nanoparticles, making them outstanding adsorbents for selectively capturing carbon dioxide and removing metal ions. Pursuing this approach holds immense potential for various environmental applications. Full article
(This article belongs to the Collection Progress in Polymer Composites and Nanocomposites)
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23 pages, 430 KB  
Article
Unmanned Agricultural Robotics Techniques for Enhancing Entrepreneurial Competitiveness in Emerging Markets: A Central Romanian Case Study
by Ioana Madalina Petre, Mircea Boșcoianu, Pompilica Iagăru and Romulus Iagăru
Agriculture 2025, 15(18), 1910; https://doi.org/10.3390/agriculture15181910 - 9 Sep 2025
Abstract
Recently, the market for miniaturized Unmanned Agricultural Robots has experienced rapid development worldwide, driven by advances in robotics, artificial intelligence and precision agriculture. These technologies are no longer confined to highly industrialized countries but are increasingly penetrating emerging economies, including Romania, where they [...] Read more.
Recently, the market for miniaturized Unmanned Agricultural Robots has experienced rapid development worldwide, driven by advances in robotics, artificial intelligence and precision agriculture. These technologies are no longer confined to highly industrialized countries but are increasingly penetrating emerging economies, including Romania, where they hold significant potential for transforming farming practices and entrepreneurial competitiveness. The purpose of the present paper is to present strategies for enhancing the competitive advantage of agricultural entrepreneurs in Romania’s Central Region. This is achieved by leveraging competitive advantage through value creation, specifically by deepening strategies for the rapid integration of new miniaturized robotic products. The research employed a mixed-methods approach, combining qualitative and quantitative techniques to investigate the ability of key stakeholders—agricultural entrepreneurs, precision agriculture product/service providers, institutional representatives, and investors—to dynamically adapt to evolving market conditions. The study’s findings reveal a strong interest and readiness among precision agriculture stakeholders to adopt advanced technologies, supported by robust operational knowledge management practices including external knowledge acquisition, strategic partnerships and data protection. Although agricultural entrepreneurs exhibit considerable adaptive and absorptive capacities—evidenced by their openness to innovation and collaboration—persistent barriers such as high equipment costs and limited financing access continue to impede the broad adoption of miniaturized robotic solutions. The study concludes by emphasizing the need for supportive policies and collaborative financing models and it suggests future research on adoption dynamics, cross-country comparisons and the role of education in accelerating agricultural robotics. Full article
(This article belongs to the Section Agricultural Economics, Policies and Rural Management)
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18 pages, 7218 KB  
Article
Energy Storage Systems for Fluctuating Energy Sources and Fluctuating Loads—Analysis of Selected Cases
by Marcin Jarnut, Jacek Kaniewski and Mariusz Buciakowski
Energies 2025, 18(18), 4792; https://doi.org/10.3390/en18184792 - 9 Sep 2025
Abstract
The dynamic development of energy storage technologies makes it possible to solve many problems related to the negative impact of renewable sources and fluctuating loads on the power and voltage quality parameters at their point of connection to the distribution grid. By absorbing [...] Read more.
The dynamic development of energy storage technologies makes it possible to solve many problems related to the negative impact of renewable sources and fluctuating loads on the power and voltage quality parameters at their point of connection to the distribution grid. By absorbing temporary energy surpluses and covering temporary energy deficits, these technologies enable the smoothing of output power profiles of wind turbines, as well as the reduction in peak power values, for example, in traction substations or fast-charging hubs for electric vehicles. This article discusses the specifics of both applications with particular emphasis on methods for sizing energy storage parameters, methods for their control, and the special effects they allow us to achieve. The methods proposed by the authors allow for the more optimal selection of energy storage parameters in existing energy facilities based on their measured power profiles. The proposed control methods, in turn, allow for not only a reduction in relative changes in power and voltage but also enable an increase in the installed power of wind farms without investing in the modernization of the distribution network, as well as reducing the contracted power of traction substations. The analyses presented in this article are based on power profile measurements of real objects, and the proposed solutions are already being implemented in power infrastructure. Full article
(This article belongs to the Special Issue Advanced Energy Storage Technologies)
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31 pages, 2318 KB  
Review
A Review of Biomass Pyrolysis for Production of Fuels: Chemistry, Processing, and Techno-Economic Analysis
by Elahe Parvari, Devinder Mahajan and Elizabeth L. Hewitt
Biomass 2025, 5(3), 54; https://doi.org/10.3390/biomass5030054 - 9 Sep 2025
Abstract
Biomass pyrolysis is a thermochemical process that breaks down organic matter in the absence of oxygen, offering a sustainable route for converting biomass into bio-oil, biochar, and syngas. This review provides a comprehensive overview of pyrolysis, focusing on its fundamental principles, modes, and [...] Read more.
Biomass pyrolysis is a thermochemical process that breaks down organic matter in the absence of oxygen, offering a sustainable route for converting biomass into bio-oil, biochar, and syngas. This review provides a comprehensive overview of pyrolysis, focusing on its fundamental principles, modes, and its applications across different industries. It covers major pyrolysis types and explores the reactors used in these processes and how key parameters, such as temperature, heating rate, and residence time, impact the distribution and quality of pyrolysis products. Special attention is given to bio-oil upgrading methods, including catalytic and non-catalytic processes, and how they affect fuel quality. The study also presents techno-economic assessments of various pathways, identifying cost-effective configurations like pyrolysis combined with hydrotreatment and heat integration. Despite encouraging advancements, scaling up bio-oil technologies continues to face significant challenges, primarily due to cost competitiveness and variability in feedstock supply. This review emphasizes the critical need for continued innovation in reactor design, catalyst efficiency, and integrated process optimization, alongside supportive policy frameworks and strategic investments to accelerate commercial deployment. Finally, this review aims to help researchers, engineers, and policymakers work together to advance pyrolysis technology as a practical solution for producing low-carbon fuels and chemicals. Full article
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23 pages, 4614 KB  
Article
Strength Tests of Selected Ropes Used in Mining Shaft Hoists After Their Replacement in Stochastic Interpretation
by Andrzej Tytko, Grzegorz Olszyna, Tomasz Rokita and Krzysztof Skrzypkowski
Materials 2025, 18(17), 4217; https://doi.org/10.3390/ma18174217 - 8 Sep 2025
Abstract
As the reserves of these raw materials continue to dwindle, their extraction is becoming increasingly difficult, with shaft depth increasing and sometimes exceeding three kilometres. As shaft depths increase, the costs, as well as the risks of mining and other shaft operations, increase [...] Read more.
As the reserves of these raw materials continue to dwindle, their extraction is becoming increasingly difficult, with shaft depth increasing and sometimes exceeding three kilometres. As shaft depths increase, the costs, as well as the risks of mining and other shaft operations, increase non-linearly. There is also a significant increase in the costs associated with condition assessment, which depend on the inspection and testing method used and increase with the lifetime of the facility. New technical and organisational solutions are emerging to meet these requirements. This paper addresses the operation of steel ropes. This article analyses the results of strength tests on two selected modern hoisting rope designs that have recently come into service. These structures are relatively unknown to users in terms of their wear. In their operation, significant problems of condition assessment and safety, as well as disqualification due to the level of wear reached, arise. Strength tests were performed using classic non-destructive methods (tensile test, torsion test, bending test) to assess the technical condition of ropes after their replacement. The tests on two rope structures carried out before and after they were put down by expert decision were analyzed. The results of these tests were statistically processed and presented graphically to determine similarities and differences. Statistical analyses were used to evaluate the results by examining the distribution of variable strength parameters. All results were commented on, and specific and general conclusions were drawn. The article presents the conclusions, the most important of which is that new and complex ropes exhibit varying degrees of wear across the layers. This is due to their compaction process. These should be useful to users of similar rope designs, personnel carrying out the obligatory tests imposed by the legislation, and those making strategic decisions regarding the operation of entire mining plants. The analyses may contribute to the subsequent assessment of the technical condition of new ropes, which in many cases have wear parameters (corrosion, strength loss, etc.) assessed in a subjective, not quantitative, manner. Full article
(This article belongs to the Section Construction and Building Materials)
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59 pages, 2624 KB  
Review
Aerogels Part 1: A Focus on the Most Patented Ultralight, Highly Porous Inorganic Networks and the Plethora of Their Advanced Applications
by Silvana Alfei
Gels 2025, 11(9), 718; https://doi.org/10.3390/gels11090718 - 8 Sep 2025
Abstract
Aerogels (AGs) are highly porous, low-density, disordered, ultralight macroscopic materials with immense surface areas. Traditionally synthesized using aqueous sol–gel chemistry, starting by molecular precursors, the nanoparticles (NPs) dispersions gelation method is nowadays the most used procedure to obtain AGs with improved crystallinity and [...] Read more.
Aerogels (AGs) are highly porous, low-density, disordered, ultralight macroscopic materials with immense surface areas. Traditionally synthesized using aqueous sol–gel chemistry, starting by molecular precursors, the nanoparticles (NPs) dispersions gelation method is nowadays the most used procedure to obtain AGs with improved crystallinity and broader structural, morphological and compositional complexity. The Sol–gel process consists of preparing a solution by hydrolysis of different precursors, followed by gelation, ageing and a drying phase, via supercritical, freeze-drying or ambient evaporation. AGs can be classified based on various factors, such as appearance, synthetic methods, chemical origin, drying methods, microstructure, etc. Due to their nonpareil characteristics, AGs are completely different from common NPs, thus covering different and more extensive applications. AGs can be applied in supercapacitors, acoustic devices, drug delivery, thermal insulation, catalysis, electrocatalysis, gas absorption, gas separation, organic and inorganic xenobiotics removal from water and air and radionucleotides management. This review provides first an analysis on AGs according to data found in CAS Content Collection. Then, an AGs’ classification based on the chemical origin of their precursors, as well as the different methods existing to prepare AGs and the current optimization strategies are discussed. Following, focusing on AGs of inorganic origin, silica and metal oxide-based AGs are reviewed, deeply discussing their properties, specific synthesis and possible uses. These classes were chosen based on the evidence that they are the most experimented, patented and marketed AGs. Several related case studies are reported, some of which have been presented in reader-friendly tables and discussed. Full article
(This article belongs to the Special Issue Recent Advances in Aerogels and Aerogel Composites)
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18 pages, 3547 KB  
Article
The Effect of Inorganic Pigments on the Rheological Properties of the Color Masterbatches from Polylactic Acid
by Marcela Hricova, Maria Petkova, Zita Tomcikova and Anna Ujhelyiova
Fibers 2025, 13(9), 122; https://doi.org/10.3390/fib13090122 - 8 Sep 2025
Abstract
Due to the large amount of plastic waste that is currently produced, the demand for ecological solutions to this situation has been growing. Many research studies in recent years have focused on polylactic acid (PLA) as a biodegradable material made from renewable resources. [...] Read more.
Due to the large amount of plastic waste that is currently produced, the demand for ecological solutions to this situation has been growing. Many research studies in recent years have focused on polylactic acid (PLA) as a biodegradable material made from renewable resources. The individual components of biodegradable materials should comply with the EN 13432 standard, which defines the properties of a “compostable” material. Careful selection of dyes and pigments is therefore important in terms of maintaining the biodegradability of the finished products. In this article, we focus on evaluating the flow properties of color masterbatches modified with inorganic biodegradable pigments. Two types of PLA were used as polymer pigment carriers, and titanium dioxide, carbon black, and two iron oxides were used as inorganic pigments. We monitored the effect of the type and concentration of pigments on the processability and rheological properties of the prepared color PLA masterbatches. The capillary viscometer and rotary rheoviscometer were used to determine rheological properties. The flow properties of color masterbatches containing 1 and 3 wt.% inorganic pigments with two types of pure polymers, PLA6100 and PLA175, were compared. We found that the color PLA masterbatches had good processability and satisfactory rheological properties, and therefore they are usable for further processing. Full article
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16 pages, 703 KB  
Review
Self-Management Behaviours in Type 2 Diabetes Across Gulf Cooperation Council Countries: An Updated Narrative Review to Enhance Patient Care
by Ashokkumar Thirunavukkarasu and Aseel Awad Alsaidan
Healthcare 2025, 13(17), 2247; https://doi.org/10.3390/healthcare13172247 - 8 Sep 2025
Abstract
Background and Objectives: Type 2 diabetes mellitus (T2DM) remains a significant public health problem across Gulf Cooperation Council (GCC) nations because of advancements in urbanization alongside behavioural lifestyle changes and genetic predispositions. Specific self-management methods are fundamental in T2DM management because they [...] Read more.
Background and Objectives: Type 2 diabetes mellitus (T2DM) remains a significant public health problem across Gulf Cooperation Council (GCC) nations because of advancements in urbanization alongside behavioural lifestyle changes and genetic predispositions. Specific self-management methods are fundamental in T2DM management because they provide better glycaemic control and decrease complications. Achieving a synthesis of updated evidence about self-management strategies and patient perception within GCC nations represents the primary objective of this narrative review. Materials and Methods: The studies included in the present review were retrieved from the Web of Science, Scopus, Medline, Saudi Digital Library, and Embase. We included peer-reviewed studies that were published from January 2020 to March 2025. The selected studies measured the self-management practices of adult T2DM patients by examining medication adherence, dietary patterns, blood glucose monitoring, and treatment barriers. Results: Research data indicate that patients demonstrate different levels of self-care management behaviours, where medication compliance is fair, but dietary patterns and physical activities remain areas of concern. High levels of knowledge deficits, cultural elements, and economic background substantially impact patients’ self-management practices. Patients indicate their need for enhanced and personalized care, better connections with healthcare providers, and interventions that consider their cultural backgrounds. Conclusions: Patients throughout the GCC region encounter ongoing difficulties that prevent them from performing their best at self-management, even though advanced healthcare facilities exist in this region. Therefore, it is critical to develop culturally sensitive patient-centered care, individualized educational programs, and adopt supportive digital solutions to enhance diabetes-related self-care management. Full article
(This article belongs to the Section Chronic Care)
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13 pages, 2211 KB  
Article
Optimization of Fermentation Parameters for the Sustainable Production of Effective Carbon Sources from Kitchen Waste to Enhance Nutrient Removal in Sewage
by Xuwei Gui, Ling Wang and Zhenlun Li
Sustainability 2025, 17(17), 8079; https://doi.org/10.3390/su17178079 - 8 Sep 2025
Abstract
In this study, we optimize the kitchen waste fermentation process by adjusting the fermentation time and temperature to prepare high-efficiency carbon sources to enhance nitrogen and phosphorus removal during sewage treatment. Simulated kitchen waste fermentation experiments were performed, and the impact on the [...] Read more.
In this study, we optimize the kitchen waste fermentation process by adjusting the fermentation time and temperature to prepare high-efficiency carbon sources to enhance nitrogen and phosphorus removal during sewage treatment. Simulated kitchen waste fermentation experiments were performed, and the impact on the pollutant removal efficiencies was analyzed using a sequence batch reactor (SBR). The results showed that the volatile fatty acid (VFA) concentration peak occurred on the first day of fermentation, the maximum increment was 543.19 mg/L, and the maximum soluble chemical oxygen demand/total nitrogen (COD/TN) ratio was 40.49. However, the highest total nitrogen (TN) removal efficiency was 70.42% on the second day of fermentation. An increase in temperature promoted organic matter release, with the highest soluble COD concentration of 22.69 g/L observed at 45 °C. Further, the maximum VFAs production (935.08–985.13 mg/L) occurred from 25 to 35 °C. In addition, the fermentation products in this temperature range also showed the optimal removal efficiencies for total phosphorus (TP) and TN at 91.50% and 79.63%, respectively. Although 15 °C and 45 °C were beneficial for COD reduction, they were not conducive to nitrogen and phosphorus removal. The energy consumption and the synergistic pollutant removal showed that the optimal fermentation conditions were 2 days at 35 °C. Under these conditions, the kitchen waste-derived carbon source achieved efficient TN and TP removal, as well as COD reduction. Therefore, these conditions provide a feasible solution for the “reduction and sustainability” of kitchen waste. Full article
(This article belongs to the Topic Advances in Organic Solid Waste and Wastewater Management)
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40 pages, 4081 KB  
Review
Two Sides of the Same Coin for Health: Adaptogenic Botanicals as Nutraceuticals for Nutrition and Pharmaceuticals in Medicine
by Alexander Panossian and Terrence Lemerond
Pharmaceuticals 2025, 18(9), 1346; https://doi.org/10.3390/ph18091346 - 8 Sep 2025
Abstract
Background: Adaptogens, commonly used as traditional herbal medicinal products for the relief of symptoms of stress, such as fatigue and exhaustion, belong to a category of physiologically active compounds related to the physiological process of adaptability to stressors. They are used both as [...] Read more.
Background: Adaptogens, commonly used as traditional herbal medicinal products for the relief of symptoms of stress, such as fatigue and exhaustion, belong to a category of physiologically active compounds related to the physiological process of adaptability to stressors. They are used both as pharmaceuticals in medicine and as dietary supplements or nutraceuticals in nutrition, depending on the doses, indications to treat diseases, or support health functions. However, such a dual-faced nature of adaptogens can lead to inconsistencies and contradictory outcomes from Food and Drug regulatory authorities in various countries. Aims: This narrative literature review aimed to (i) specify five steps of pharmacological testing of adaptogens, (ii) identify the sources of inconsistencies in the assessment of evidence the safety, efficacy, and quality of multitarget adaptogenic botanicals, and (iii) propose potential solutions to address some food and drug regulatory issues, specifically adaptogenic botanicals used for prevention and treatment of complex etiology diseases including stress-induced, and aging-related disorders. Overview: This critically oriented narrative review is focused on (i) five steps of pharmacological testing of adaptogens are required in a sequential order, including appropriate in vivo and in vitro models in animals, in vitro model, and mechanisms of action by a proper biochemical assay and molecular biology technique in combination with network pharmacology analysis, and clinical trials in stress-induced and aging-related disorders; (ii) the differences between the requirements for the quality of pharmaceuticals and dietary supplements of botanical origin; (iii) progress, trends, pitfalls, and challenges in the adaptogens research; (iv) inadequate assignment of some plants to adaptogens, or insufficient scientific data in case of Eurycoma longifolia; (v) inconsistencies in botanical risk assessments in the case of Withania somnifera. Conclusions: This narrative review highlights the importance of harmonized standards, transparent methodologies, and a balanced, evidence-informed approach to ensure consumers receive effective and safe botanicals. Future perspectives and proposed solutions include (i) establish internationally harmonized guidelines for evaluating botanicals based on their intended use (e.g., pharmaceutical vs. dietary supplement), incorporating traditional use data alongside modern scientific methods; (ii) encourage peer review and transparency in national assessments by mandating public disclosure of methodologies, data sources, and expert affiliations; (iii) create a tiered evidence framework that allows differentiated standards of proof for traditional botanical supplements versus pharmaceutical candidates; (iv) promote international scientific dialogs among regulators, researchers, and industry to develop consensus positions and avoid unilateral bans that may lack scientific rigor; (v) formally recognize adaptogens a category of natural products for prevention stress induced brain fatigue, behavioral, and aging related disorders. Full article
(This article belongs to the Special Issue Network Pharmacology of Natural Products, 2nd Edition)
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