Search Results (580)

This study presents a headset-type biofluorometric gas sensor incorporating a CMOS camera for continuous, non-invasive monitoring of transcutaneous ethanol from the ear canal. The sensor employs alcohol dehydrogenase (ADH) to catalyze the NAD⁺-to-NADH conversion during ethanol oxidation, enabling quantitative measurement through NADH fluorescence detection (λ_ex = 340 nm, λ_em = 490 nm). The integrated system comprises a wireless CMOS camera, an ADH-immobilized cotton mesh enzyme membrane, UV-LED excitation source, optical bandpass filters, and a dual convex lens assembly housed in a 3D-printed headset powered by a lithium battery. Key improvements include a 3.5-fold enhancement in fluorescence collection efficiency achieved through optimized dual convex lens configuration. Systematic screening of seven cotton mesh materials identified Iwatsuki cotton mesh as the optimal enzyme immobilization substrate, exhibiting minimal autofluorescence and 14.2-fold higher water retention capacity compared to H-PTFE membranes. The glutaraldehyde-crosslinked ADH-immobilized cotton mesh maintained enzymatic activity for over 45 min with a 10-fold improvement in signal-to-noise ratio. The system demonstrated a dynamic detection range spanning 10 ppb to 10 ppm for gaseous ethanol and exhibited high selectivity against interfering volatile organic compounds in skin gas, including methanol, acetaldehyde, formaldehyde, and acetone. Human experiments validated the system’s practical performance. Following alcohol consumption, subjects wore the device for 50 min while real-time fluorescence monitoring captured dynamic ethanol concentration changes in the ear canal. The dose-dependent fluorescence response—approximately 2-fold higher at 0.4 g/kg versus 0.04 g/kg alcohol intake—correlated well with calibration data. This headset-type biofluorometric sensor enables unrestrained continuous monitoring of ear canal ethanol, providing a novel wearable platform for alcohol metabolism assessment with potential applications in health monitoring and clinical research. Full article

Ultraviolet (UV) radiation is a recognized human carcinogen, and topical sunscreens remain the primary strategy for photoprotection. As community pharmacies represent trusted sources of skincare products, evaluating the composition of sunscreens distributed through this channel is particularly relevant. This cross-sectional market analysis investigated UV filters used in sunscreen products available in Lithuanian community pharmacies in November–December 2025. Products were identified through online pharmacy catalogs and assessed for labeled Sun Protection Factor (SPF), number and type of UV filters, and filter combinations in accordance with Regulation (EC) No 1223/2009. A total of 467 products from 98 brands were included, and 26 distinct UV filters were identified. Triazine derivatives predominated, particularly bis-ethylhexyloxyphenol methoxyphenyl triazine (64.67%) and ethylhexyl triazone (58.03%). Most products (61.67%) were labeled SPF ≥ 50 and contained multiple UV filters (mean 4.29 ± 1.66), with significantly more filters in SPF ≥ 50 formulations (p < 0.001). These results indicate that sunscreen products available in Lithuanian pharmacies are dominated by high-SPF formulations and selective multi-filter systems, providing region-specific insights relevant to regulatory oversight and consumer exposure assessment. Full article

Welders constitute an occupational group that is particularly exposed to high-risk hazards arising from harmful radiation emitted during welding, including ultraviolet (UV) and infrared (IR) radiation, as well as visible (VIS) radiation, whose high intensity causes glare. Effective protection of the eyes and face is provided by welding shields equipped with automatic welding filters (AWFs), which activate automatically upon arc ignition. Their switching time is the most important protective parameter, as it has a direct impact on the user’s visual health. The objective of the work is to present a novel test stand for determining AWFs switching and holding times, which provides advanced possibilities for evaluating all types of AWFs. Until now, performance and safety levels have been determined based on numerical values: switching time and hold time. For the first time, it is possible to analyze the darkening and clearing phenomena over time with an interpretation of graphical results. Importantly, it is possible to analyze the symmetry of filter properties, using two measurement channels, which is crucial for binocular and curved (panoramic) AWFs. The results obtained for two types of AWFs mounted in goggles with a one-piece and a binocular visor differ from each other. Switching time differences between the left and right measurement channels were about 6–7% for the one-piece visor goggles (G1) and about 3–4% for the binocular goggles (G2). The dispersion of results confirmed the importance of the two measurement channels, which was not previously practiced. The test stand, designed in accordance with the requirements of the new European standards (EN ISO 18526-2:2020, EN ISO 16321-2:2021), can be used for prototyping and for AWF certification purposes. Full article

The development of effective water disinfection treatment processes will be crucial to help food producers save water and cope with the inevitable challenges resulting from increases in human population and climate change, while promoting sustainable agriculture. The inactivation efficiency of UV-C light emitting diodes (LEDs) that emit light at 280 nm was tested as a disinfection method. Water samples from a horticulture industry were collected and characterized in terms of total microorganisms, total coliforms, Escherichia coli and enterococci as well as parameters that influence photolysis such as the percent transmittance of the irrigation water (that, due to the nutrients added for plant growth, was extremely low and varied between 40 and 55%). Nevertheless, laboratory scale results showed that three single small UV LEDs that emit light at 280 nm were extremely efficient for the inactivation of microorganisms present at occurrence levels in the irrigation water samples, as well as Phytophthora capsici and Escherichia coli spiked in sterile distilled water and filtered irrigation water samples. Overall, the findings demonstrate that UV-C LEDs operating at 280 nm represent a promising sustainable disinfection strategy for modern food production systems facing tightening environmental and public-health pressures. Full article

The crystal structure regulation of Ti₃O₅ by Al₂O₃ doping and its effect on the optical properties of TiO₂ films prepared by electron beam evaporation were systematically studied. Ti₃O₅ coating materials with different Al₂O₃ doping contents (0–50 at%) were prepared by vacuum melting, and the corresponding TiO₂ films were deposited on K9 glass substrates via electron beam vacuum evaporation. The phase structure, phase transition temperature, chemical composition and optical properties of the materials and films were characterized by XRD, DSC, EDS, XPS, UV-Vis and AFM. Results show that Al₂O₃ doping induces the phase transition of Ti₃O₅ from a room-temperature stable β-phase to a high-temperature stable λ-phase, with complete transition at 5 at% doping. Al³⁺ with a smaller ionic radius causes lattice contraction and local distortion of Ti₃O₅, enabling stabilization at room temperature of the λ-phase. For TiO₂ films, 12.5 at% doping is the optimal state with the stable composition transfer under this condition. With the increase in Al₂O₃ doping content, the refractive index and extinction coefficient of TiO₂ films decrease continuously, while the optical band gap and surface roughness show an increasing trend. The changes in optical properties are mainly ascribed to the low refractive index of Al₂O₃, lattice compressive strain effect and oxygen vacancy passivation induced by Al³⁺. This study clarifies the regulation effect of Al₂O₃ doping on Ti₃O₅ phase transition and TiO₂ film optical properties, and provides theoretical basis and experimental reference for the doping modification of TiO₂ films and their practical applications in consumer electronics and optical filter devices. Full article

A protozoa leads a rapid onset of symptoms, with high mortality rates in the rearing of the planktotrophic larvae of the tropical holothurian Isostichopus fuscus for aquaculture. This study aimed to determine the effect of temperature on the infection parameters and the larvae size with/without parasites in its five development stages: T1–EA (250–300 μm), T2–MA-I (300–600 μm), T3–MA-II (600–900 μm), T4–A (1.1–1.3 mm), and T5–LA (≈500 μm). Eight 500 L conical tanks with filtered and UV-sterilized seawater with 0.2 larvae mL⁻¹ under two temperature treatments (low: 23.0 ± 2.5 °C, high: 27.0 ± 0.5 °C). Thirty larvae per replicate at intervals of 4–5 days were sampled until day 25. A total of 1200 larvae were examined, and a total of 21,715 parasites were counted. A total of 97% of parasites were found under low temperature conditions. The DSI and survival significantly varied in relation to the temperature and time. The highest prevalence and intensity, 62.5 ± 5.7% and 130.5 ± 13.0, respectively, were observed at T4 at low temperature. At 18 d, larvae without parasites were larger (1494.1 ± 52.2 μm) than larvae with parasites (1237.7 ± 24.4 μm, p < 0.05) at 25 d. These findings suggest that elevated temperature functions as a key regulator in mitigating parasitic infections in auricularia larvae of I. fuscus. Full article

Background/Objectives: Gastro-resistant multiparticulate systems are designed to protect drugs in acidic environments and to ensure intestinal release. In practice, the method of administration may need to be modified: pellet-containing capsules opened or tablets halved for patients with swallowing difficulties, yet the type of liquid used for administration is often not specified. This study examined the stability of gastro-resistant coated pellets after exposure to various aqueous media prior to ingestion. Methods: To evaluate administration instructions, 103 Summaries of Product Characteristics of gastro-resistant products were reviewed. Pellets were produced using a bottom-spray fluidized bed process and coated with Eudragit L 30 D-55. Dissolution testing in pH 1.2 medium was performed after pre-soaking the pellets for 5, 15, and 30 min in beverages with various pH and conductivity. Drug release was measured by UV-VIS method, and morphological changes were assessed by image analysis. Marketed gastro-resistant products were also examined visually. Results: SmPC review revealed that the beverage for intake was frequently unspecified. Among the tested beverages differences in pH and conductivity were observed. Alkaline medicinal mineral waters induced increased and time-dependent premature drug release compared to tap and filtered water. Image analysis indicated a reduction in surface area after exposure to alkaline media. Conclusions: Contact with non-specified aqueous media before swallowing may weaken the protective function of gastro-resistant films. More explicit recommendations on suitable administration manipulation and media may improve therapeutic consistency. Full article

Alcoholic fermentation in winemaking is a complex bioprocess governed by physicochemical parameters such as temperature, density, pH, CO₂ and redox potential, which critically affect yeast metabolism and wine quality. This review provides an integrated analysis of fermentative dynamics and emerging sensorization technologies, highlighting how their combined implementation enables real-time monitoring and advanced control in precision enology. Advances in conventional physicochemical sensors, spectroscopic techniques (NIR/MIR/UV-Vis) and non-conventional devices (e-noses, electronic tongues) integrated into IoT platforms enable continuous data acquisition, overcoming traditional manual sampling limitations. Predictive modeling, including kinetic models, machine learning approaches (e.g., Random Forest, XGBoost) and model predictive control (MPC/NMPC), supports anomaly detection, optimization of enological interventions and energy-efficient thermal management, while virtual sensors based on Kalman filters improve the estimation of non-measurable states (e.g., biomass, ethanol kinetics). Despite current challenges in calibration and interoperability, these innovations foster sustainable and reproducible winemaking under climate variability and pave the way for digital twins and semi-autonomous fermentation systems. Full article

Underwater vehicles (UVs) are pivotal for ocean exploration, yet their effectiveness is fundamentally constrained by acoustic performance in noisy and dynamic seas. Self-noise, non-stationary interference, and extreme conditions not only degrade sensing, navigation, and stealth but also cascade into losses in propulsion efficiency, actuation reliability, and control precision. This review provides a system-performance-oriented synthesis of advances across four key areas: bioinspired and intelligent noise reduction materials/structures, active noise control and adaptive signal processing, noise-robust navigation and collaborative localization, and deep learning-enhanced acoustic perception. Key findings indicate that bioinspired surfaces reduce flow noise by ≈5 dB, adaptive filtering improves $\mathrm{SNR}$ by up to 20 dB, and distributed robust filtering ensures multi-AUV consistency under uncertainty. These developments collectively establish acoustic performance not as a parallel metric, but as a fundamental enabler and critical bottleneck for the integrated propulsion-actuation-control stack of next-generation UVs. Consequently, this review outlines viable pathways toward high-performance acoustic–mechanical integration. Full article

Sunscreens are essential for photoprotection, but conventional inorganic UV filters raise concerns regarding marine toxicity. This study investigated hydroxyapatite (HAp) derived from skipjack, tongol, and salmon bone waste as a potential synergistic booster for Tinosorb^® S (TS). HAp powders were prepared via alkaline treatment and calcination at 900 °C. XRD and XRF results confirmed highly crystalline HAp as the dominant phase. While 10% HAp alone provided negligible UV protection, a pronounced synergistic effect was observed in 1:1 hybrid formulations (5% HAp:5% TS), significantly enhancing Sun Protection Factor (SPF) and Ultraviolet A Protection Factor (UVAPF). Notably, particle-size refinement of salmon-derived HAp (SM–HAp) yielded an SPF of approximately 35, comparable to a commercial HAp counterpart. This improvement was suggested to be associated with enhanced dispersion, film uniformity, and particle–matrix interactions, which might contribute to achieving PA++++ protection. All formulations complied with microbiological and heavy metal safety standards. These results indicated that fish bone-derived HAp could potentially serve as a viable and sustainable functional additive derived from marine biowaste for the development of high-performance hybrid sunscreens, promoting biomaterial valorization in the cosmetic industry. Full article

The occurrence and spatial distribution of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), fragrances, UV filters and photoinitiators were investigated in surface sediments of Nerbioi-Ibaizabal estuary between 2005 and 2013, in 2020. Samples were extracted by focused ultrasound solid–liquid extraction technique and analyzed by gas chromatography coupled with mass spectrometry. Total PAHs, PCBs, OCPs, musks, UV filters and photoinitiators concentrations ranged between not detected (n.d.) and 43000 ng g⁻¹, n.d. and 2500 ng g⁻¹, n.d. and 820 ng g⁻¹, n.d. and 880 ng g⁻¹, n.d. and 91 ng g⁻¹ and from nd to 120 ng g⁻¹, respectively. Hexachlorocyclohexanes (HCHs) were ubiquitous in the estuary, suggesting that these compounds, although banned, leach from landfills. The PCB concentrations showed a decreasing trend. Ecological risk assessments based on sediment quality guidelines (SQGs) and risk quotient (RQ) suggested semi-volatile organic compounds could represent a potential ecological risk in the Nerbioi-Ibaizabal estuary. Full article

Compost-derived humic acids (HAs) and fulvic acids (FAs) play an essential role in enhancing soil microbial diversity and activity by facilitating metabolic processes through electron transfer. Herein, the effect of bioleaching dewatered sludge (BDS) in comparison with filter press dewatered sludge (FDS) on the electron transfer capacity (ETC) of humic substances during composting was investigated as a novel attempt. A variety of characterization methods including UV-Vis, FTIR, 3D-EEM, and electrochemical measurements, were used to explore the change in humic substances during composting. The results indicated that bioleaching treatment significantly influenced the organic matter composition and hindered the accumulation of redox-active functional groups during composting. Notably, the ETC of HA increased by 24.07% in the FDS group but declined by 40.62% in the BDS group. This divergence stemmed from the organic matter loss during bioleaching, leading to reduced quinone-like and tryptophan-like substances associated with electron transfer in HA during composting. Furthermore, BDS showed lower pH, water content, and organic matter, but higher concentrations of ammonium nitrogen (${\mathrm{NH}}_4^{+}\text{-}\mathrm{N}$) and ammonia nitrogen ${\mathrm{NH}}_3^{-}\text{-}\mathrm{N}$, all of which potentially influenced humification efficiency. These findings not only clarify the electron-transfer dynamics of humic fractions but also highlight the importance of optimizing sludge pretreatment for improved composting performance and resource recovery. Full article

Background/Objectives: Insect oils have gained attention as sustainable cosmetic ingredients due to their bioactive lipid content. This study aimed to characterize oils from cricket and to evaluate their safety, biological activities, and performance in sunscreen formulations. Methods: Oils were extracted from Gryllus bimaculatus, Teleogryllus mitratus, and Acheta domesticus by cold pressing following hot-air drying. Fatty acid composition was determined using gas chromatography–mass spectrometry. Safety was assessed by cytotoxicity testing in normal human dermal fibroblasts (NHDF) and the hen’s egg chorioallantoic membrane (HET-CAM) assay. Antioxidant and anti-inflammatory activities were evaluated by intracellular reactive oxygen species (ROS) and nitric oxide (NO^•) assays. Based on biological performance, T. mitratus oil (TMO) was incorporated into sunscreen creams containing physical and chemical ultraviolet (UV) filters. Physical stability, viscosity, pH, sun protection factor (SPF), persistent pigment darkening/ultraviolet A protection factor (PPD/UVA-PF), and blue light protection were evaluated. Results: All cricket oils were non-cytotoxic to NHDF cells and were classified as non-irritating in the HET-CAM assay. TMO exhibited the strongest antioxidant activity, reducing intracellular ROS and significantly inhibiting NO^• production in lipopolysaccharide-stimulated cells. Only TMO showed measurable UVA protection (PPD/UVA-PF = 12.1, PA+++). Sunscreen creams formulated with TMO achieved higher photoprotective efficacy than olive oil-based creams, with SPF values up to 40.51 and PPD/UVA-PF up to 39.17. The inclusion of foundation pigments further increased SPF to 43.09 and enhanced blue light protection to 35.1%. Conclusions: TMO is a safe and effective multifunctional ingredient that enhances sunscreen performance and supports sustainable cosmetic formulation. Full article

This study presents a SCAPS-1D-based numerical optimization of an organic ultraviolet (UV) photodetector employing an FTO/PTB7/Spiro-OMeTAD/Au device architecture. The novelty of this work lies in a simulation-guided, UV-specific optimization strategy that combines thickness engineering, controlled doping, and contact work-function tuning to achieve intrinsic spectral selectivity without external optical filters. We systematically optimize material and device parameters, including active layer thicknesses, donor and acceptor densities, and the metal electrode work function, to enhance responsivity, detectivity, and spectral performance. Simulations identify optimal thicknesses of 1200 nm for PTB7 and 1000 nm for Spiro-OMeTAD, with donor concentrations of 1 × 10²⁰ cm⁻³ and 1 × 10¹⁸ cm⁻³, respectively. A comparative contact analysis demonstrates that replacing aluminum with gold (Au) forms a near-ohmic back contact, leading to improved hole extraction and suppressed dark current due to favorable energy-level alignment. The optimized device achieves a peak external quantum efficiency of approximately 80% in the 300–400 nm ultraviolet range, with a responsivity up to 0.4 A/W. The UV selectivity originates from the absorption characteristics of PTB7 combined with suppressed long-wavelength charge collection, resulting in a negligible response in the visible–near-infrared region. These results confirm the device’s strong potential for high-sensitivity, solar-blind UV photodetection. By integrating practical material selection with physically consistent SCAPS-1D optoelectronic modeling, this work provides a robust design framework to guide the development of next-generation organic UV photodetectors for environmental sensing, biomedical diagnostics, and wearable optoelectronics. Full article

Scientific concern regarding the widespread occurrence of micropollutants (MPs) in aquatic environments has been growing. Background/Objectives: Since conventional wastewater and drinking water (DW) treatment plants are generally unable to completely remove MPs, their presence in DW may occur, potentially posing adverse effects on public health. Highly sensitive analytical methods are crucial, as MPs may occur at very low concentrations in DW, usually at ng L⁻¹ levels. Methods: An offline solid-phase extraction ultra-high performance liquid-chromatography coupled to tandem mass-spectrometry (SPE-UHPLC-MS/MS) method was optimized and validated for the determination of 23 MPs in DW, including 12 pharmaceuticals, 9 pesticides, and 2 UV-filters, listed in the 2 most recent European Union (EU) Decisions (2022/1307 and 2025/439) for surface water monitoring, and in the revised EU Urban Wastewater Treatment Directive (2024/3019). The validated method was applied to 50 DW samples collected across Portugal. Results: The optimized SPE-UHPLC-MS/MS method showed high analytical sensitivity, achieving method detection limits below 1.50 ng L⁻¹. Up to 3 MPs were detected per sample, with quantifiable concentrations of each ranging from 0.28 to 98.8 ng L⁻¹. However, benzotriazole and dimoxystrobin exceeded the upper limits of their calibration curves (i.e., concentrations higher than 133 and 117 ng L⁻¹, respectively) in one and 3 of the collected samples, respectively. Considering all analyzed samples, 4 (fluconazole, irbesartan, dimoxystrobin, and benzotriazole) of the 23 target compounds were detected. Hazard quotient values for all detected MPs were well below 0.1. Conclusions: The validated SPE-UHPLC-MS/MS method is suitable for the sensitive determination of MPs in DW. Some MPs were detected, with concentrations indicating no expected human health risks under the conditions evaluated. Further monitoring campaigns should be conducted in the future, with compounds exceeding the limits of the calibration curves requiring special attention. Full article