- Abstract
Modeling of New VHR Inhibitors Based on 4H-1,3,5-Oxadiazine Derivatives
- Elizaveta R. Lominoga,
- Pavlo V. Zadorozhnii,
- Olha O. Hrek,
- Vadym V. Kiselev and
- Aleksandr V. Kharchenko
Vaccinia H1-related phosphatase (VHR) is a dual-specific phosphatase that is a promising potential target for the treatment of many human diseases. In this work, we have proposed a series of 6-(4-chlorophenyl)-N-aryl-4-(trichloromethyl)-4H-1,3,5-oxad...