Search Results (411)

Introduction: Secure infant/child–caregiver attachment is crucial for the development of social and emotional functioning and can affect long-term outcomes, such as adult relationships, but it may also be influenced by prenatal and early childhood risk factors. Children with a history of prenatal alcohol exposure (PAE) have a complex spectrum of strengths and difficulties and often have the additional risk of early life adversity. There is some evidence that children with PAE are at increased risk of insecure attachment, but it is unclear whether this is consistent or why it is the case. No published review has focused on the relationship between PAE and attachment. Methods: A systematic search of seven academic databases using the PRISMA Extension for Scoping Reviews (PRISMA-ScR) guidelines was undertaken by two reviewers to identify primary studies that have focused on the relationship between PAE and attachment. Quality assessments were undertaken using the Quality of Observational Cohort and Cross-Sectional Studies tool, and the report was written following the PRISMA-ScR checklist. Results: A total of 4199 records were returned from the database searches. A total of 11 studies (eight peer-reviewed papers and three dissertations), published between 1987 and 2021, met the criteria. Five studies showed that PAE was related to insecure or disorganised attachment, two of which showed that infant irritability and caregiver–infant interaction mediated this relationship. The other six studies found no significant relationship between PAE and attachment. Conclusions: This scoping review demonstrates that there is a dearth of published research on this topic, and none that takes advantage of more recent understanding of the relationship between adverse childhood experiences and neurodevelopmental disorders. There is some evidence that PAE may impact the attachment relationship via caregiver–infant interaction and infant irritability, but further studies, including those that assess the additional impact of early life adversity, are needed. Full article

(1) Background: the influence of adverse childhood experiences (ACEs) on depression is well-documented. Identifying protective factors to counteract ACEs’ detrimental effects is vital for public mental health. The efficacy of the “shift-and-persist” strategy as a mitigating factor against ACEs’ impact remains to be clarified. This study aimed to elucidate the relationship between ACEs and depression by testing a mediated moderation model, focusing on the moderating role of the “shift-and-persist” strategy and the mediating role of perceived everyday discrimination. (2) Methods: the research involved 1263 university students from Henan Province, China. A cross-sectional design was employed to test our theoretical model. Participants completed an online survey with assistance from trained research assistants. (3) Results: the study found that ACEs are a significant predictor of depressive symptoms in Chinese college students. The “shift-and-persist” strategy serves as a protective factor; high levels of this strategy weaken the predictive effect of ACEs on depression. Additionally, this strategy reduces the incidence of perceived everyday discrimination (PED) among those with ACEs, thereby alleviating depressive symptoms. (4) Conclusions: the “shift-and-persist” strategy effectively reduces PED and, consequently, depressive symptoms in individuals with ACEs, highlighting its potential as a protective factor in mental health interventions. Full article

Borderline Personality Disorder (BPD) is marked by emotional dysregulation, instability in self-image and relationships, and high impulsivity. While functional magnetic resonance imaging (fMRI) studies have provided valuable insights into the disorder’s neural correlates, electroencephalography (EEG) may capture real-time brain activity changes relevant to BPD’s rapid emotional shifts. This review summarizes findings from studies investigating resting state and task-based EEG in individuals with BPD, highlighting common neurophysiological markers and their clinical implications. A targeted literature search (1980–2025) was conducted across databases, including PubMed, Google Scholar, and Cochrane. The search terms combined “EEG” or “electroencephalography” with “borderline personality disorder” or “BPD”. Clinical trials and case reports published in English were included if they recorded and analyzed EEG activity in BPD. A total of 24 studies met the inclusion criteria. Findings indicate that individuals with BPD often show patterns consistent with chronic hyperarousal (e.g., reduced alpha power and increased slow-wave activity) and difficulties shifting between vigilance states. Studies examining frontal EEG asymmetry reported varying results—some linked left-frontal activity to heightened hostility, while others found correlations between right-frontal shifts and dissociation. Childhood trauma, mentalization deficits, and dissociative symptoms were frequently predicted or correlated with EEG anomalies, underscoring the impact of adverse experiences on neural regulation—however, substantial heterogeneity in methods, small sample sizes, and comorbid conditions limited study comparability. Overall, EEG research supports the notion of altered arousal and emotion regulation circuits in BPD. While no single EEG marker uniformly defines the disorder, patterns such as reduced alpha power, increased theta/delta activity, and shifting frontal asymmetries converge with core BPD features of emotional lability and interpersonal hypersensitivity. More extensive, standardized, and multimodal investigations are needed to establish more reliable EEG biomarkers and elucidate how early trauma and dissociation shape BPD’s neurophysiological profile. Full article

Background/Objectives: Borderline Personality Disorder (BPD) frequently overlaps with trauma-related conditions, particularly PTSD and Complex PTSD (cPTSD). Adverse Childhood Experiences (ACEs)—especially emotional and sexual abuse—are considered key factors in the development of emotion dysregulation and dissociation. This study investigates the impact of different ACE dimensions on borderline symptomatology, emotion dysregulation, and dissociative symptoms. Methods: Eighty-three BPD patients were assessed using standardized self-report questionnaires: CTQ-SF (ACEs), DERS (emotion dysregulation), DES (dissociation), BSL-23 (borderline symptoms), and PDS-3 (post-traumatic symptoms). Analyses included bivariate correlations, Structural Equation Modeling (SEM), and Exploratory Graph Analysis (EGA). Results: Emotional abuse significantly predicted borderline symptoms, while sexual abuse predicted dissociation. Emotion dysregulation was strongly associated with both borderline and dissociative symptoms, emerging as a central node in the symptom network. EGA confirmed the clustering of dissociative symptoms with sexual abuse and the centrality of emotion dysregulation across domains. Conclusions: Findings support the role of specific ACEs in shaping the clinical expression of BPD. Emotion dysregulation acts as a key transdiagnostic factor linking trauma history to borderline and dissociative features. These results underscore the importance of trauma-informed assessments and interventions, such as DBT and DBT-PTSD, tailored to individual ACE profiles. Full article

Childhood trauma has been associated with criminal behaviour and a variety of psychopathologies. Furthermore, it is known that emotional dysregulation (ED) predicts anxiety and depression and can be a product of traumatic experiences. In order to develop effective interventions for offenders’ rehabilitation and prevent recidivism, it is essential to fully understand their mental health and its relation with previous child trauma experiences and ED. This study involved a sample of 100 male inmates incarcerated in seven different prisons in the northern region of Portugal. The following measures were used: the Childhood Trauma Questionnaire-Short Form (CTQ-SF), the International Trauma Questionnaire (ITQ), the Generalized Anxiety Disorder-7 (GAD-7), the Patient Health Questionnaire (PHQ-9), and the Difficulties in Emotional Regulation Scale (DERS). Our findings suggest that individuals who experienced physical and sexual abuse are more likely to perpetrate violent crimes and that ED increases anxiety and depressive symptoms in individuals with traumatic symptoms. In conclusion, it is imperative to provide psychological support to this population, and interventions need to be adapted according to trauma exposure. Full article

Backgrounds: Adverse Childhood Experiences (ACEs) are linked to early and long-lasting mental health issues and somatic multimorbidity. Emerging evidence suggests ACEs may also accelerate physical frailty in old age. This study examines the association between ACEs and sarcopenia, an ageing-related disease and core component of frailty. Methods: Baseline data from the Canadian Longitudinal Study on Aging (CLSA), including 25,327 participants aged 45–85 years (50.3% female sex) were analyzed. Sarcopenia was defined using the revised European Working Group of Sarcopenia in Older People (EWGSOP2) guidelines. ACE were assessed via the Childhood Experiences of Violence Questionnaire and the National Longitudinal Study of Adolescent to Adult Health Wave III questionnaire, covering eight ACE categories. Multiple logistic regression models examined the association between the number of ACE count and sarcopenia, which were adjusted for age, sex, education, income, and ethnicity. Results: Given a significant interaction between age and ACE (p < 0.01), analyses were stratified into four age groups (45–54, 55–64, 65–74, and 75–85 years). A significant association only emerged in the oldest group (75–85 years; OR = 0.93 [95% CI: 0.86–1.00], p = 0.043), but this result was in the opposite direction we hypothesized. Sensitivity analyses confirmed findings across different operationalisations of ACE and sarcopenia. Conclusions: Higher ACE exposure was not associated with sarcopenia in middle aged and older adults. The unexpected protective association in the oldest-old subgroup may reflect survival bias. Age-stratified longitudinal studies are needed to clarify this relationship. Full article

Relevant biopsychosocial factors, including testosterone (T) and cortisol (C) levels, adverse childhood experiences (ACEs), and difficulties in emotion regulation, have been implicated in IPV perpetration. However, further research is needed to clarify how biomarkers and psychosocial variables interact. The authors herein predicted that emotion regulation difficulties would moderate the association between ACES and IPV perpetration. The sample consisted of 30 IPV perpetrators aged 18 to 51 (M = 30.80, SD = 8.43) and 30 control non-perpetrator participants aged 18–35 (M = 24.13; SD = 4.28). All participants provided saliva samples to assess T and C levels and completed a sociodemographic questionnaire that included questions related to ACEs, and the Difficulties in Emotion Regulation Scale (DERS). Higher levels of T and T/C, greater difficulties in emotion regulation, and higher prevalence of ACEs were found to significantly differentiate the IPV perpetrators from the non-IPV perpetrators. However, difficulties in emotional regulation did not emerge as a significant moderator between these variables, and only one of four subscales of the DERS, emotional awareness, was significantly associated with both testosterone and IPV. These results are in accord with meta-analytic results which found that DERS scores are higher in IPV perpetrators than non-perpetrators but that there was a very small association between emotional dysregulation and IPV (0.14), and emotional awareness was not associated with IPV. Similarly, effect sizes for ER variables are strong as differentiators of perpetrators and non-perpetrators.. Given the relative strength of psychological variables as moderators of childhood trauma and IPV, anger would appear to be a much stronger moderator as it is a much stronger predictor of IPV than emotional dysregulation. Full article

Background and Objectives: Emerging evidence indicates that individuals exposed to adverse childhood experiences (ACEs) face elevated risks for various chronic illnesses. However, the association between ACEs and osteoporosis risk remains underexplored, particularly regarding potential modifications by genetic susceptibility. This prospective cohort study aims to examine the relationship of ACEs with incident osteoporosis and investigate interactions with polygenic risk score (PRS). Materials and Methods: This study analyzed 124,789 UK Biobank participants initially free of osteoporosis. Cumulative ACE burden (emotional neglect, emotional abuse, physical neglect, physical abuse, sexual abuse) was ascertained through validated questionnaires. Multivariable-adjusted Cox proportional hazards models assessed osteoporosis risk during a median follow-up of 12.8 years. Moderation analysis examined genetic susceptibility interactions using a standardized PRS incorporating osteoporosis-related SNPs. Results: Among 2474 incident osteoporosis cases, cumulative ACEs showed dose–response associations with osteoporosis risk (adjusted hazard ratio [HR]_{per one-unit increase} = 1.07, 95% confidence interval [CI] 1.04–1.11; high ACEs [≥3 types] vs. none: HR = 1.26, 1.10–1.43). Specifically, emotional neglect (HR = 1.14, 1.04–1.25), emotional abuse (HR = 1.14, 1.03–1.27), physical abuse (HR = 1.17, 1.05–1.30), and sexual abuse (HR = 1.15, 1.01–1.31) demonstrated comparable effect sizes. Sex-stratified analysis revealed stronger associations in women. Joint exposure to high ACEs/high PRS tripled osteoporosis risk (HR = 3.04, 2.46–3.76 vs. low ACEs/low PRS) although G × E interaction was nonsignificant (P-interaction = 0.10). Conclusions: These results suggest that ACEs conferred incremental osteoporosis risk independent of genetic predisposition. These findings support the inclusion of ACE screening in osteoporosis prevention strategies and highlight the need for targeted bone health interventions for youth exposed to ACEs. Full article

Background: Youth with chronic rheumatologic diseases undergo medical experiences that can lead to post-traumatic stress disorder (PTSD). Understudied in pediatric rheumatology, medical PTSD can be significantly distressing and impairing. Objective: This study explored the prevalence of medical PTSD symptoms in youth with chronic inflammatory arthritis and associated factors, including pain, disease activity, mental health history, and anxiety sensitivity. Methods: A cross-sectional study of 50 youth (ages 8–18) with juvenile idiopathic arthritis (JIA) and childhood-onset systemic lupus erythematous (cSLE) was conducted at a pediatric rheumatology clinic. Participants completed self-report measures assessing post-traumatic stress symptoms (CPSS-V), pain, anxiety sensitivity (CASI), pain-related self-efficacy (CSES), adverse childhood experiences (ACEs), and fibromyalgia symptoms (PSAT). Clinical data included diagnoses, disease activity, treatment history, and demographics. Results: Forty percent had trauma symptoms in the moderate or more severe range. The 14% likely meeting criteria for probable medical PTSD were older (median 17 vs. 15 years, p = 0.005), had higher pain scores (median 4 vs. 3, p = 0.008), more ACEs (median 3 vs. 1, p = 0.005), higher anxiety sensitivity scores (median 39 vs. 29, p = 0.008), and higher JIA disease activity scores (median cJADAS-10 11.5 vs. 7.5, p = 0.032). They were also more likely to report a history of depression (71 vs. 23%, p = 0.020). No associations were found with hospitalization or injected/IV medication use. Conclusions: Medical trauma symptoms are prevalent in youth with chronic inflammatory arthritis. Probable PTSD was associated with pain and psychological distress. These findings support the need for trauma-informed care in pediatric rheumatology. Full article

Adverse childhood experiences (ACEs) in early childhood may increase the risk of emotional behavioral problems (EBPs); however, few studies have explored the longitudinal effect of ACEs in early childhood on later EBPs and their underlying mechanisms. This study examined the serial mediating role of psychological resilience (PR) and problematic media use (PMU) in the relationship between ACEs in early childhood and EBPs. Participants included 534 three-year-old children (mean age of 33.29 years, SD = 3.97) and their parents from Wuhu, China. The parents completed online questionnaires measuring children’s ACEs, PR, and demographic information in September 2022 (Time 1), children’s PMU in September 2023 (Time 2), and EBPs in September 2024 (Time 3). Macro Process 6 was used to test the serial mediating effects of PR and PMU. A total of 5000 bootstrap samples were used to estimate the 95% confidence intervals. The results revealed that ACEs in early childhood did not directly predict EPBs. PR (b = 0.132 (95% CI [0.051, 0.221])) mediated the relationship between ACEs and children’s EBPs. PR and PMU also played a serial mediating role in the association of ACEs and children’s EBPs (b = 0.026, 95% CI [0.008, 0.054]). Our findings highlight the importance of improving PR and addressing PMU when designing interventions targeting Chinese preschoolers exposed to ACEs. Full article

The COVID-19 pandemic is considered a potentially traumatic event, as it introduced new challenges and threats to people around the world, disrupting daily life due to the restrictions imposed. The psychological defenses of individuals mobilized to deal with stress reactions are influenced by a set of factors, including previous traumatic experiences, which can amplify the current trauma. Recognizing that people exposed to adverse childhood experiences (ACEs) have increased risks of an array of adverse mental and physical health outcomes throughout life, the present study aimed to investigate the relationship between ACEs—more specifically, child abuse and child neglect—and PTSD symptoms in a sample of European adults during the pandemic. A sample of 8459 participants (67.1% female and 32.9% male, with a mean of 43.95 years old) was evaluated. The survey questionnaire included questions on sociodemographic and clinical characteristics, the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5), and the Adverse Childhood Experiences (ACEs) questionnaire. According to our findings, younger women who have suffered from child abuse or child neglect are more likely to develop PTSD symptoms. The most significant factor influencing the PTSD risk was child neglect, contrary to many studies that indicate that child abuse is the most impactful adverse childhood experience. Full article

Dissociative symptoms may result from both neurobiological conditions, such as Attention-Deficit/Hyperactivity Disorder (ADHD), and traumatic events/exposure, such as Post-Traumatic Stress Disorder (PTSD) and Adverse Childhood Experiences (ACEs). However, identifying whether dissociative manifestations are associated with ADHD symptoms or trauma-related manifestations may drive clinicians to select the most effective intervention. Four hundred participants from the general population completed an online survey and were classified based on the presence of PTSD, ACEs, or ADHD symptoms. We compared the severity of dissociation and its dimensions across groups using the Dissociative Experiences Scale-II (DES-II) and explored its association with ADHD symptoms, PTSD manifestations, and ACEs. Dissociative symptoms were more pronounced in individuals with combined ADHD and PTSD or ACEs, but a hierarchical pattern of dissociation severity was also observed in isolated symptoms: ADHD > PTSD > ACEs. More specifically, participants who reported ADHD symptoms obtained higher scores on the Amnesia dimension of the DES-II than PTSD and more severe Absorption subscores than individuals reporting ACEs. Correlational analyses confirmed that DES-II scores were mostly associated with the scale evaluating the severity of ADHD symptoms rather than those evaluating trauma-related manifestations. These findings suggest that neurodevelopmental vulnerabilities, such as ADHD, may play a more significant role in dissociative symptomatology than trauma-related disorders. Full article

Although common, natural disasters (NDs) remain little studied, and their aggregate psychological impact is unknown. No aggregate measure of ND exposure could be located. This study reports the development and preliminary validation of the Natural Disaster Scale (NDS). In a sample of 131 US adults, disaster exposure was measured for NDs, for childhood and adult human disasters, for psychological flexibility, and for social support. Criteria included general distress, simple and complex PTSD, and life satisfaction. The NDS showed good internal consistency. Eleven of thirteen items loaded on a single factor. After controlling demographic factors, social support, and psychological flexibility, the NDS predicted general distress, simple PTSD, and satisfaction with life. In comparison, adult human adversity/disaster predicted general distress and simple PTSD, while childhood human adversity/disaster predicted complex PTSD and satisfaction with life. Similarly sized effects were found for human and natural disasters, except that only childhood adversity predicted complex PTSD. Demographic factors were insignificant except that age predicted life satisfaction. Because NDs may lead to distress, simple PTSD, and diminished life satisfaction, appraising lifelong exposure to NDs may be important for treatment. Those exposed to NDs may benefit from trauma-informed care. Fostering psychological flexibility, as proposed in the ACT therapy, is suggested as an important treatment focus for addressing the effects of human and natural disasters. Full article

Over the last two and a half decades, there has been a surge of research into adverse childhood experiences (ACEs). ACEs have been found to be a significant predictor of mental health outcomes in adulthood, and researchers have begun to explore the relationship between ACEs and mental health outcomes in athletes. However, to the best of the authors’ knowledge, no study has directly compared the mental health of student-athletes to non-student-athletes in the context of exposure to ACEs. In the present study, we compared psychological outcomes observed in college students (123 student-athletes and 149 non-student-athletes) on two mental health variables—depressive symptoms and difficulties in emotion regulation—at one university in the U.S. Results indicated that exposure to ACEs had a significant effect on both depressive symptoms and difficulties in emotion regulation, while student-athlete status only had a significant effect on depressive symptoms. There was no significant interaction effect between exposure to ACEs and student-athlete status. This pattern of main effects and an absence of an interaction effect remained even when the psychological trait of hardiness was controlled for. The implications and limitations of these results will be discussed. Full article

Previous research has found the link between adverse childhood experiences (ACEs) and externalizing behaviors later in adolescence and adulthood. However, limited studies have explored longitudinal trajectories of aggressive behaviors affected by ACEs. This study aimed to investigate how aggressive behaviors change over time and compare the trajectories of aggressive behaviors between children with three or fewer (low-risk ACEs) and those with four or more ACEs (high-risk ACEs) with the role of school connectedness on the trajectories of aggressive behaviors over time. The study sample consisted of 4231 children collected by the Future of Families and Child Wellbeing Study, a longitudinal birth cohort study focusing on children in high-risk families across 20 U.S. cities. The mean age of the sample was 15.59 years, with 81.9% of the participants being minorities and 51.9% being boys. The results indicated that children with high-risk ACEs showed twice as high levels of aggressive behaviors as those with low-risk ACEs. School connectedness decreased the starting level and change rate of aggressive behavior for children with high-risk ACEs, while it decreased the starting level of aggressive behavior for those with low-risk ACEs. These findings underscore the protective role of school connectedness on aggressive behavior. Practitioners and policymakers need to make an effort to build safe and supportive social environments for all children, especially for children with high-risk ACEs. Full article