Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (450)

Search Parameters:
Keywords = bluetooth low energy

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
20 pages, 2177 KB  
Article
Real-Time Safety Alerting System for Dynamic, Safety-Critical Environments
by Nima Abdollahpour, Mehrdad Moallem and Mohammad Narimani
Automation 2025, 6(3), 43; https://doi.org/10.3390/automation6030043 - 8 Sep 2025
Abstract
This paper presents a proof-of-concept real-time safety alerting system for safety-critical environments such as construction sites. Key components of the system include Bluetooth Low Energy (BLE) devices for indoor localization, integrated with a customized Android application using the Framework for Internal Navigation and [...] Read more.
This paper presents a proof-of-concept real-time safety alerting system for safety-critical environments such as construction sites. Key components of the system include Bluetooth Low Energy (BLE) devices for indoor localization, integrated with a customized Android application using the Framework for Internal Navigation and Discovery (FIND). Administrative control and data management are handled by a server-side component, supported by an interactive website for real-time safety monitoring. The architecture supports safety zoning and employs machine learning algorithms, including k-NN, Random Forest, and SVM, for analyzing localization data. Experimental validation in a laboratory setup demonstrates a localization accuracy of 97%, a response time of 1.2 s, and a maximum spatial error of 1.2 m. These results highlight the system’s reliability and potential for enhancing safety compliance in real-world deployment scenarios. Full article
(This article belongs to the Section Intelligent Control and Machine Learning)
Show Figures

Figure 1

23 pages, 16144 KB  
Article
Smart Bluetooth Stakes: Deployment of Soil Moisture Sensors with Rotating High-Gain Antenna Receiver on Center Pivot Irrigation Boom in a Commercial Wheat Field
by Samuel Craven, Austin Bee, Blake Sanders, Eliza Hammari, Cooper Bond, Ruth Kerry, Neil Hansen and Brian A. Mazzeo
Sensors 2025, 25(17), 5537; https://doi.org/10.3390/s25175537 - 5 Sep 2025
Viewed by 324
Abstract
Realization of the goals of precision agriculture is dependent on prescribing irrigation strategies matched to spatiotemporal variations in soil moisture on commercial farms. However, the scale at which these variations occur is not well understood. A high-spatial-density network of sensors with the ability [...] Read more.
Realization of the goals of precision agriculture is dependent on prescribing irrigation strategies matched to spatiotemporal variations in soil moisture on commercial farms. However, the scale at which these variations occur is not well understood. A high-spatial-density network of sensors with the ability to measure and report data over the course of a growing season is needed. In this work, design of the low-profile Smart Bluetooth Stake spatiotemporal soil moisture mapping system is presented. Smart stakes use Bluetooth Low Energy to communicate 64 MHz soil moisture impedance measurements from ground level to a receiver mounted on the center-pivot irrigation boom and equipped with a rotating high-gain parabolic antenna. Smart stakes can remain in the ground throughout the entire growing season without disrupting farm operations. A system of 86 sensors was deployed on a 50-hectare commercial field near Elberta, Utah, during the final growth stage of a crop of winter wheat. Different receiver antenna configurations were tested over the course of several weeks which included two full irrigation cycles. In the high-gain antenna configuration, data was successfully collected from 75 sensors, with successful packet transmission at ranges of approximately 600 m. Enough data was collected to construct a spatiotemporal moisture map of the field over the course of an irrigation cycle. Smart Bluetooth Stakes constitute an important advance in the spatial density achievable with direct sensors for precision agriculture. Full article
(This article belongs to the Special Issue Feature Papers in Smart Agriculture 2025)
Show Figures

Figure 1

20 pages, 3380 KB  
Article
The Real-Time Estimation of Respiratory Flow and Mask Leakage in a PAPR Using a Single Differential-Pressure Sensor and Microcontroller-Based Smartphone Interface in the Development of a Public-Oriented Powered Air-Purifying Respirator as an Alternative to Lockdown Measures
by Yusaku Fujii
Sensors 2025, 25(17), 5340; https://doi.org/10.3390/s25175340 - 28 Aug 2025
Viewed by 494
Abstract
In this study, a prototype system was developed as a potential alternative to lockdown measures against the spread of airborne infectious diseases such as COVID-19. The system integrates real-time estimation functions for respiratory flow and mask leakage into a low-cost powered air-purifying respirator [...] Read more.
In this study, a prototype system was developed as a potential alternative to lockdown measures against the spread of airborne infectious diseases such as COVID-19. The system integrates real-time estimation functions for respiratory flow and mask leakage into a low-cost powered air-purifying respirator (PAPR) designed for the general public. Using only a single differential-pressure sensor (SDP810) and a controller (Arduino UNO R4 WiFi), the respiratory flow (Q3e) is estimated from the differential pressure (ΔP) and battery voltage (Vb), and both the wearing status and leak status are transmitted to and displayed on a smartphone application. For evaluation, a testbench called the Respiratory Airflow Testbench was constructed by connecting a cylinder–piston drive to a mannequin head to simulate realistic wearing conditions. The estimated respiratory flow Q3e, calculated solely from ΔP and Vb, showed high agreement with the measured flow Q3m obtained from a reference flow sensor, confirming the effectiveness of the estimation algorithm. Furthermore, an automatic leak detection method based on the time-integrated value of Q3e was implemented, enabling the detection of improper wearing. This system thus achieves respiratory flow estimation and leakage detection based only on ΔP and Vb. In the future, it is expected to be extended to applications such as pressure control synchronized with breathing activity and health monitoring based on respiratory and coughing analysis. This platform also has the potential to serve as the foundation of a PAPR Wearing Status Network Management System, which will contribute to societal-level infection control through the networked sharing of wearing status information. Full article
Show Figures

Figure 1

27 pages, 7467 KB  
Article
Bluetooth Protocol for Opportunistic Sensor Data Collection on IoT Telemetry Applications
by Pablo García-Rivada, Ángel Niebla-Montero, Paula Fraga-Lamas and Tiago M. Fernández-Caramés
Electronics 2025, 14(16), 3281; https://doi.org/10.3390/electronics14163281 - 18 Aug 2025
Viewed by 352
Abstract
With the exponential growth of Internet of Things (IoT) and wearable devices for home automation and industrial applications, vast volumes of data are continuously generated, requiring efficient data collection methods. IoT devices, being resource-constrained and typically battery-dependent, require lightweight protocols that optimize resource [...] Read more.
With the exponential growth of Internet of Things (IoT) and wearable devices for home automation and industrial applications, vast volumes of data are continuously generated, requiring efficient data collection methods. IoT devices, being resource-constrained and typically battery-dependent, require lightweight protocols that optimize resource usage and energy consumption. Among such IoT devices, this article focuses on Bluetooth-based beacons due to their low latency and the advantage of not requiring pairing for communications. Specifically, to tackle the limitations of beacons in terms of bandwidth and transmission frequency, this article proposes a protocol that modifies beacon frames to include up to three parameters per frame and that allows for making use of configurable beaconing intervals based on the specific requirements of the communications scenario. Moreover, the use of the proposed protocol leads to increased data rates for beaconing transmissions, providing a low latency and a flexible configuration that permits adjusting different parameters. The proposed solution enables end-to-end interoperability in Opportunistic Edge Computing (OEC) networks by integrating a lightweight bridge module to transparently manage BLE advertisement segments. To demonstrate the performance of the devised opportunistic protocol, it is evaluated across multiple scenarios (i.e., in a short-distance reference scenario, inside a home with diverse obstacles, inside a building, outdoors and in an industrial scenario), showing its flexibility and ability to collect substantial data volumes from heterogeneous IoT devices. Full article
(This article belongs to the Special Issue Applications of Sensor Networks and Wireless Communications)
Show Figures

Figure 1

20 pages, 9514 KB  
Article
The Behavior of an IoT Sensor Monitoring System Using a 5G Network and Its Challenges in 6G Networking
by Georgios Gkagkas, Vasiliki Karamerou, Angelos Michalas, Michael Dossis and Dimitrios J. Vergados
Electronics 2025, 14(16), 3167; https://doi.org/10.3390/electronics14163167 - 8 Aug 2025
Viewed by 524
Abstract
The recent advances in 5G and beyond wireless networking have enabled the possibility of using the cellular network as the infrastructure for wireless sensor networks, due to the high bandwidth availability and the reduced cost per data unit. In this paper, we perform [...] Read more.
The recent advances in 5G and beyond wireless networking have enabled the possibility of using the cellular network as the infrastructure for wireless sensor networks, due to the high bandwidth availability and the reduced cost per data unit. In this paper, we perform an evaluation of the 5G infrastructure for sensor networks in order to quantify the performance in terms of energy efficiency and bandwidth within a testing environment. We used an ESP32 sensor with BLE-connected sensing devices for environmental conditions, and a Raspberry Pi with the Waveshare SIM8200EA-M2 5G module for cellular connectivity. We measured the power usage of each component of the system, in real conditions, as well as the power consumption for different bandwidth usage scenarios, and the end-to-end delay of the system. The results showed that the system is capable of achieving the required delay and bandwidth; however, the energy efficiency of the specific setup leaves room for improvement. Full article
(This article belongs to the Special Issue Wireless Sensor Network: Latest Advances and Prospects)
Show Figures

Figure 1

22 pages, 728 KB  
Article
Multi-Layered Security Assessment in mHealth Environments: Case Study on Server, Mobile and Wearable Components in the PHGL-COVID Platform
by Edi Marian Timofte, Mihai Dimian, Serghei Mangul, Alin Dan Potorac, Ovidiu Gherman, Doru Balan and Marcel Pușcașu
Appl. Sci. 2025, 15(15), 8721; https://doi.org/10.3390/app15158721 - 7 Aug 2025
Viewed by 490
Abstract
The growing use of mobile health (mHealth) technologies adds complexity and risk to the healthcare environment. This paper presents a multi-layered cybersecurity assessment of an in-house mHealth platform (PHGL-COVID), comprising a Docker-based server infrastructure, a Samsung Galaxy A55 smartphone, and a Galaxy Watch [...] Read more.
The growing use of mobile health (mHealth) technologies adds complexity and risk to the healthcare environment. This paper presents a multi-layered cybersecurity assessment of an in-house mHealth platform (PHGL-COVID), comprising a Docker-based server infrastructure, a Samsung Galaxy A55 smartphone, and a Galaxy Watch 7 wearable. The objective was to identify vulnerabilities across the server, mobile, and wearable components by emulating real-world attacks and conducting systematic penetration tests on each layer. Tools and methods specifically tailored to each technology were applied, revealing exploitable configurations, insecure Bluetooth Low Energy (BLE) communications, and exposure of Personal Health Records (PHRs). Key findings included incomplete container isolation, BLE metadata leakage, and persistent abuse of Android privacy permissions. This work delivers both a set of actionable recommendations for developers and system architects to strengthen the security of mHealth platforms, and a reproducible audit methodology that has been validated in a real-world deployment, effectively bridging the gap between theoretical threat models and practical cybersecurity practices in healthcare systems. Full article
(This article belongs to the Special Issue Advances in Cyber Security)
Show Figures

Figure 1

25 pages, 3258 KB  
Article
MTRSRP: Joint Design of Multi-Triangular Ring and Self-Routing Protocol for BLE Networks
by Tzuen-Wuu Hsieh, Jian-Ping Lin, Chih-Min Yu, Meng-Lin Ku and Li-Chun Wang
Sensors 2025, 25(15), 4773; https://doi.org/10.3390/s25154773 - 3 Aug 2025
Viewed by 343
Abstract
This paper presents the multi-triangular ring and self-routing protocol (MTRSRP), which is a new decentralized strategy designed to boost throughput and network efficiency in multiring scatternets. MTRSRP comprises two primary phases: leader election and scatternet formation, which collaborate to establish an effective multi-triangular [...] Read more.
This paper presents the multi-triangular ring and self-routing protocol (MTRSRP), which is a new decentralized strategy designed to boost throughput and network efficiency in multiring scatternets. MTRSRP comprises two primary phases: leader election and scatternet formation, which collaborate to establish an effective multi-triangular ring topology. In the leader election phase, nodes exchange broadcast messages to gather neighbor information and elect coordinators through a competitive process. The scatternet formation phase determines the optimal number of rings based on the coordinator’s collected node information and predefined rules. The master nodes then send unicast connection requests to establish piconets within the scatternet, following a predefined role table. Intra- and inter-bridge nodes were activated to interconnect the piconets, creating a cohesive multi-triangular ring scatternet. Additionally, MTRSRP incorporates a self-routing addressing scheme within the triangular ring architecture, optimizing packet transmission paths and reducing overhead by utilizing master/slave relationships established during scatternet formation. Simulation results indicate that MTRSRP with dual-bridge connectivity outperforms the cluster-based on-demand routing protocol and Bluetooth low-energy mesh schemes in key network transmission performance metrics such as the transmission rate, packet delay, and delivery ratio. In summary, MTRSRP significantly enhances throughput, optimizes routing paths, and improves network efficiency in multi-ring scatternets through its multi-triangular ring topology and self-routing capabilities. Full article
(This article belongs to the Special Issue Advances in Wireless Sensor and Mobile Networks)
Show Figures

Figure 1

18 pages, 3440 KB  
Article
Ambient Electromagnetic Wave Energy Harvesting Using Human Body Antenna for Wearable Sensors
by Dairoku Muramatsu and Kazuki Amano
Sensors 2025, 25(15), 4689; https://doi.org/10.3390/s25154689 - 29 Jul 2025
Viewed by 856
Abstract
Wearable sensors are central to health-monitoring systems, but the limited capacity of compact batteries poses a challenge for long-term and maintenance-free operation. In this study, we investigated ambient electromagnetic wave (AEMW) energy harvesting using a human body antenna (HBA) as a means to [...] Read more.
Wearable sensors are central to health-monitoring systems, but the limited capacity of compact batteries poses a challenge for long-term and maintenance-free operation. In this study, we investigated ambient electromagnetic wave (AEMW) energy harvesting using a human body antenna (HBA) as a means to supply power to wearable sensors. The power density and frequency distribution of AEMWs were measured in diverse indoor, outdoor, and basement environments. We designed and fabricated a flexible HBA–circuit interface electrode, optimized for broadband impedance matching when worn on the body. Experimental comparisons using a simulated AEMW source demonstrated that the HBA outperformed a conventional small whip antenna, particularly at frequencies below 300 MHz. Furthermore, the outdoor measurements indicated that the power harvested by the HBA was estimated to be −31.9 dBm (0.64 μW), which is sufficient for the intermittent operation of low-power wearable sensors and Bluetooth Low Energy modules. The electromagnetic safety was also evaluated through numerical analysis, and the specific absorption rate was confirmed to be well below the international safety limits. These findings indicate that HBA-based AEMW energy harvesting provides a practical and promising approach to achieving battery-maintenance-free wearable devices. Full article
(This article belongs to the Special Issue Energy Harvesting Technologies for Wireless Sensors)
Show Figures

Figure 1

31 pages, 4668 KB  
Article
BLE Signal Processing and Machine Learning for Indoor Behavior Classification
by Yi-Shiun Lee, Yong-Yi Fanjiang, Chi-Huang Hung and Yung-Shiang Huang
Sensors 2025, 25(14), 4496; https://doi.org/10.3390/s25144496 - 19 Jul 2025
Viewed by 613
Abstract
Smart home technology enhances the quality of life, particularly with respect to in-home care and health monitoring. While video-based methods provide accurate behavior analysis, privacy concerns drive interest in non-visual alternatives. This study proposes a Bluetooth Low Energy (BLE)-enabled indoor positioning and behavior [...] Read more.
Smart home technology enhances the quality of life, particularly with respect to in-home care and health monitoring. While video-based methods provide accurate behavior analysis, privacy concerns drive interest in non-visual alternatives. This study proposes a Bluetooth Low Energy (BLE)-enabled indoor positioning and behavior recognition system, integrating machine learning techniques to support sustainable and privacy-preserving health monitoring. Key optimizations include: (1) a vertically mounted Data Collection Unit (DCU) for improved height positioning, (2) synchronized data collection to reduce discrepancies, (3) Kalman filtering to smooth RSSI signals, and (4) AI-based RSSI analysis for enhanced behavior recognition. Experiments in a real home environment used a smart wristband to assess BLE signal variations across different activities (standing, sitting, lying down). The results show that the proposed system reliably tracks user locations and identifies behavior patterns. This research supports elderly care, remote health monitoring, and non-invasive behavior analysis, providing a privacy-preserving solution for smart healthcare applications. Full article
Show Figures

Figure 1

29 pages, 8416 KB  
Article
WSN-Based Multi-Sensor System for Structural Health Monitoring
by Fatih Dagsever, Zahra Sharif Khodaei and M. H. Ferri Aliabadi
Sensors 2025, 25(14), 4407; https://doi.org/10.3390/s25144407 - 15 Jul 2025
Viewed by 3127
Abstract
Structural Health Monitoring (SHM) is an essential technique for continuously assessing structural conditions using integrated sensor systems during operation. SHM technologies have evolved to address the increasing demand for efficient maintenance strategies in advanced engineering fields, such as civil infrastructure, aerospace, and transportation. [...] Read more.
Structural Health Monitoring (SHM) is an essential technique for continuously assessing structural conditions using integrated sensor systems during operation. SHM technologies have evolved to address the increasing demand for efficient maintenance strategies in advanced engineering fields, such as civil infrastructure, aerospace, and transportation. However, developing a miniaturized, cost-effective, and multi-sensor solution based on Wireless Sensor Networks (WSNs) remains a significant challenge, particularly for SHM applications in weight-sensitive aerospace structures. To address this, the present study introduces a novel WSN-based Multi-Sensor System (MSS) that integrates multiple sensing capabilities onto a 3 × 3 cm flexible Printed Circuit Board (PCB). The proposed system combines a Piezoelectric Transducer (PZT) for impact detection; a strain gauge for mechanical deformation monitoring; an accelerometer for capturing dynamic responses; and an environmental sensor measuring temperature, pressure, and humidity. This high level of functional integration, combined with real-time Data Acquisition (DAQ) and precise time synchronization via Bluetooth Low Energy (LE), distinguishes the proposed MSS from conventional SHM systems, which are typically constrained by bulky hardware, single sensing modalities, or dependence on wired communication. Experimental evaluations on composite panels and aluminum specimens demonstrate reliable high-fidelity recording of PZT signals, strain variations, and acceleration responses, matching the performance of commercial instruments. The proposed system offers a low-power, lightweight, and scalable platform, demonstrating strong potential for on-board SHM in aircraft applications. Full article
Show Figures

Figure 1

17 pages, 5876 KB  
Article
Optimization of Knitted Strain Sensor Structures for a Real-Time Korean Sign Language Translation Glove System
by Youn-Hee Kim and You-Kyung Oh
Sensors 2025, 25(14), 4270; https://doi.org/10.3390/s25144270 - 9 Jul 2025
Viewed by 434
Abstract
Herein, an integrated system is developed based on knitted strain sensors for real-time translation of sign language into text and audio voices. To investigate how the structural characteristics of the knit affect the electrical performance, the position of the conductive yarn and the [...] Read more.
Herein, an integrated system is developed based on knitted strain sensors for real-time translation of sign language into text and audio voices. To investigate how the structural characteristics of the knit affect the electrical performance, the position of the conductive yarn and the presence or absence of elastic yarn are set as experimental variables, and five distinct sensors are manufactured. A comprehensive analysis of the electrical and mechanical performance, including sensitivity, responsiveness, reliability, and repeatability, reveals that the sensor with a plain-plated-knit structure, no elastic yarn included, and the conductive yarn positioned uniformly on the back exhibits the best performance, with a gauge factor (GF) of 88. The sensor exhibited a response time of less than 0.1 s at 50 cycles per minute (cpm), demonstrating that it detects and responds promptly to finger joint bending movements. Moreover, it exhibits stable repeatability and reliability across various angles and speeds, confirming its optimization for sign language recognition applications. Based on this design, an integrated textile-based system is developed by incorporating the sensor, interconnections, snap connectors, and a microcontroller unit (MCU) with built-in Bluetooth Low Energy (BLE) technology into the knitted glove. The complete system successfully recognized 12 Korean Sign Language (KSL) gestures in real time and output them as both text and audio through a dedicated application, achieving a high recognition accuracy of 98.67%. Thus, the present study quantitatively elucidates the structure–performance relationship of a knitted sensor and proposes a wearable system that accounts for real-world usage environments, thereby demonstrating the commercialization potential of the technology. Full article
(This article belongs to the Section Wearables)
Show Figures

Figure 1

23 pages, 678 KB  
Article
Unified Probabilistic and Similarity-Based Position Estimation from Radio Observations
by Max Werner, Markus Bullmann, Toni Fetzer and Frank Deinzer
Sensors 2025, 25(13), 4092; https://doi.org/10.3390/s25134092 - 30 Jun 2025
Viewed by 340
Abstract
We propose a modeling approach for position estimation based on the observed radio propagation in an environment. The approach is purely similarity-based and therefore free of explicit physical assumptions. What distinguishes it from classical related methods are probabilistic position estimates. Instead of just [...] Read more.
We propose a modeling approach for position estimation based on the observed radio propagation in an environment. The approach is purely similarity-based and therefore free of explicit physical assumptions. What distinguishes it from classical related methods are probabilistic position estimates. Instead of just providing a point estimate for a given signal sequence, our model returns the distribution of possible positions as continuous probability density function, which allows for appropriate integration into recursive state estimation systems. The estimation procedure starts by using a kernel to compare incoming data with reference recordings from known positions. Based on the obtained similarities, weights are assigned to the reference positions. An arbitrarily chosen density estimation method is then applied given this assignment. Thus, a continuous representation of the distribution of possible positions in the environment is provided. We apply the solution in a Particle Filter (PF) system for smartphone-based indoor localization. The approach is tested both with radio signal strength (RSS) measurements (Wi-Fi and Bluetooth Low Energy RSSI) and round-trip time (RTT) measurements, given by Wi-Fi Fine Timing Measurement. Compared to distance-based models, which are dedicated to the specific physical properties of each measurement type, our similarity-based model achieved overall higher accuracy at tracking pedestrians under realistic conditions. Since it does not explicitly consider the physics of radio propagation, the proposed model has also been shown to work flexibly with either RSS or RTT observations. Full article
Show Figures

Figure 1

19 pages, 4492 KB  
Article
Ergonomic Innovation: A Modular Smart Chair for Enhanced Workplace Health and Wellness
by Zilvinas Rakauskas, Vytautas Macaitis, Aleksandr Vasjanov and Vaidotas Barzdenas
Sensors 2025, 25(13), 4024; https://doi.org/10.3390/s25134024 - 27 Jun 2025
Viewed by 972
Abstract
The increasing prevalence of sedentary lifestyles poses significant global health challenges, including obesity, diabetes, musculoskeletal disorders, and cardiovascular issues. This paper presents the design and development of a universal smart chair system aimed at mitigating the adverse effects of prolonged sitting. The proposed [...] Read more.
The increasing prevalence of sedentary lifestyles poses significant global health challenges, including obesity, diabetes, musculoskeletal disorders, and cardiovascular issues. This paper presents the design and development of a universal smart chair system aimed at mitigating the adverse effects of prolonged sitting. The proposed solution integrates a pressure sensor, vibration motors, an LED strip, and Bluetooth Low-Energy (BLE) communication into a modular and adaptable design. Powered by an STM32WB55CGU6 microcontroller and a rechargeable lithium-ion battery system, the smart chair monitors sitting duration and the user’s posture, and provides alerts through tactile, visual, and auditory notifications. A complementary mobile application allows users to customize sitting time thresholds, monitor activity, and assess battery status. Designed for universal compatibility, the system can be adapted to various chair types. Technical and functional testing demonstrated reliable performance, with the chair operating for over eight workdays on a single charge. The smart chair offers an innovative, cost-effective approach to improving workplace ergonomics and health outcomes, with potential for further enhancements such as posture monitoring. A pilot study with 83 students at VILNIUS TECH showed that the smart chair detected correct posture with 94.78% accuracy, and 97.59% of users responded to alerts by adjusting their posture within an average of 3.27 s. Full article
(This article belongs to the Collection Sensors for Globalized Healthy Living and Wellbeing)
Show Figures

Figure 1

19 pages, 6328 KB  
Article
Seamless Indoor–Outdoor Localization Through Transition Detection
by Jaehyun Yoo
Electronics 2025, 14(13), 2598; https://doi.org/10.3390/electronics14132598 - 27 Jun 2025
Viewed by 399
Abstract
Indoor localization techniques operate independently of Global Navigation Satellite Systems (GNSSs), which are primarily designed for outdoor environments. However, integrating indoor and outdoor positioning often leads to inconsistent and delayed location estimates, especially at transition zones such as building entrances. This paper develops [...] Read more.
Indoor localization techniques operate independently of Global Navigation Satellite Systems (GNSSs), which are primarily designed for outdoor environments. However, integrating indoor and outdoor positioning often leads to inconsistent and delayed location estimates, especially at transition zones such as building entrances. This paper develops a probabilistic transition detection algorithm to identify indoor, outdoor, and transition zones, aiming to enhance the continuity and accuracy of positioning. The algorithm leverages multi-source sensor data, including WiFi Received Signal Strength Indicator (RSSI), Bluetooth Low-Energy (BLE) RSSI, and GNSS metrics such as carrier-to-noise ratio. During transitions, the system incorporates Inertial Measurement Unit (IMU)-based tracking to ensure smooth switching between positioning engines. The outdoor engine utilizes a Kalman Filter (KF) to fuse IMU and GNSS data, while the indoor engine employs fingerprinting techniques using WiFi and BLE. This paper presents experimental results using three distinct devices across three separate buildings, demonstrating superior performance compared to both Google’s Fused Location Provider (FLP) algorithm and a GPS. Full article
(This article belongs to the Special Issue Wireless Sensor Network: Latest Advances and Prospects)
Show Figures

Figure 1

13 pages, 1792 KB  
Article
A High-Sensitivity, Bluetooth-Enabled PCB Biosensor for HER2 and CA15-3 Protein Detection in Saliva: A Rapid, Non-Invasive Approach to Breast Cancer Screening
by Hsiao-Hsuan Wan, Chao-Ching Chiang, Fan Ren, Cheng-Tse Tsai, Yu-Siang Chou, Chun-Wei Chiu, Yu-Te Liao, Dan Neal, Coy D. Heldermon, Mateus G. Rocha and Josephine F. Esquivel-Upshaw
Biosensors 2025, 15(6), 386; https://doi.org/10.3390/bios15060386 - 15 Jun 2025
Viewed by 1617
Abstract
Breast cancer is a leading cause of cancer-related mortality worldwide, requiring efficient diagnostic tools for early detection and monitoring. Human epidermal growth factor receptor 2 (HER2) is a key biomarker for breast cancer classification, typically assessed using immunohistochemistry (IHC). However, IHC requires invasive [...] Read more.
Breast cancer is a leading cause of cancer-related mortality worldwide, requiring efficient diagnostic tools for early detection and monitoring. Human epidermal growth factor receptor 2 (HER2) is a key biomarker for breast cancer classification, typically assessed using immunohistochemistry (IHC). However, IHC requires invasive biopsies and time-intensive laboratory procedures. In this study, we present a biosensor integrated with a reusable printed circuit board (PCB) and functionalized glucose test strips designed for rapid and non-invasive HER2 detection in saliva. The biosensor achieved a limit of detection of 10−15 g/mL, 4 to 5 orders of magnitude more sensitive than the enzyme-linked immunosorbent assay (ELISA), with a sensitivity of 95/dec and a response time of 1 s. In addition to HER2, the biosensor also detects cancer antigen 15-3 (CA15-3), another clinically relevant breast cancer biomarker. The CA15-3 test demonstrated an equally low limit of detection, 10−15 g/mL, and a higher sensitivity, 190/dec, further validated using human saliva samples. Clinical validation using 29 saliva samples confirmed our biosensor’s ability to distinguish between healthy, in situ breast cancer, and invasive breast cancer patients. The system, which integrates a Bluetooth Low-Energy (BLE) module, enables remote monitoring, reduces hospital visits, and enhances accessibility for point-of-care and mobile screening applications. This ultra-sensitive, rapid, and portable biosensor can serve as a promising alternative for breast cancer detection and monitoring, particularly in rural and underserved communities. Full article
(This article belongs to the Special Issue Aptamer-Based Biosensors for Point-of-Care Diagnostics)
Show Figures

Figure 1

Back to TopTop