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Keywords = breast melanosis

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9 pages, 16077 KB  
Case Report
Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature
by Angela Santoro, Giuseppe Angelico, Vincenzo Fiorentino, Qianqian Zhang, Saveria Spadola, Angela Carlino, Alejandro Martin Sanchez, Gianluca Franceschini, Gian Franco Zannoni and Antonino Mulè
Diagnostics 2021, 11(4), 709; https://doi.org/10.3390/diagnostics11040709 - 15 Apr 2021
Cited by 4 | Viewed by 3987
Abstract
Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis [...] Read more.
Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential. Full article
(This article belongs to the Special Issue Challenging Topics in Breast Cancer Diagnosis and Treatment)
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