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25 pages, 5650 KB  
Article
Do Ecological Patterns Persist in Highly Impacted Urban Wetlands? A Spatiotemporal Analysis of Aquatic Macrophytes and Limnological Variability in a Peruvian Coastal Wetland
by Flavia Valeria Rivera-Cáceda, José Antonio Arenas-Ibarra and Sofía Isabel Urrutia-Ramírez
Diversity 2026, 18(4), 214; https://doi.org/10.3390/d18040214 - 7 Apr 2026
Abstract
Urban coastal wetlands along the Peruvian Pacific coast are increasingly affected by urban expansion, pollution, and hydrological alterations, compromising their ecological integrity. In this context, the spatiotemporal variation of the aquatic macrophyte community and its relationship with limnological conditions and drivers of change [...] Read more.
Urban coastal wetlands along the Peruvian Pacific coast are increasingly affected by urban expansion, pollution, and hydrological alterations, compromising their ecological integrity. In this context, the spatiotemporal variation of the aquatic macrophyte community and its relationship with limnological conditions and drivers of change were evaluated in the Santa Rosa wetland (Chancay, Lima). The objective is to evaluate the spatiotemporal variation of the aquatic macrophyte community in the Santa Rosa wetland and analyze its relationship with physicochemical limnological variables and drivers of change. Sampling was conducted during two contrasting hydrological seasons in 2022: T1 (low-water season) and T2 (high-water season), at six sampling points (P1–P6). Physicochemical variables (water depth, temperature, pH, conductivity, total dissolved solids—TDS, total suspended solids—TSS, dissolved oxygen—DO, turbidity, nitrate—NO3, ammonium—NH4+, phosphate—PO43−, and dissolved organic matter—DOM) were measured, and the relative abundance of aquatic macrophytes was evaluated. Drivers of change were identified through direct observation and a structured matrix, with phosphate a PCoA performed to summarize spatiotemporal trends. Data were analyzed using Principal Component Analysis (PCA), Co-inertia analysis, and Multi-Response Permutation Procedures (MRPP). Significant spatiotemporal variation was observed in physicochemical parameters (p < 0.05), with moderate covariation between the two matrices (RV = 0.47). A total of ten aquatic macrophyte species were recorded, with higher abundance of Pontederia crassipes and Pistia stratiotes in T1, and Hydrocotyle ranunculoides and Bacopa monnieri in T2. The most relevant drivers of change were solid waste, livestock grazing, organic contamination, and urban expansion. Spatial heterogeneity was observed in the drivers of change affecting the Santa Rosa wetland, forming a mosaic of areas with different impact profiles. Despite multiple anthropogenic pressures, the Santa Rosa wetland maintains a limnological structure and a functionally coupled macrophyte community, suggesting that essential ecological processes are maintained within the temporal scope of this study. The observed covariation between physicochemical conditions and vegetation confirms the persistence of essential ecological processes, even within an altered urban context. This study demonstrates that integrating biotic components, limnological variables, and drivers of change is fundamental to understanding and monitoring the ecological dynamics of urban wetlands along the Peruvian coast. Full article
(This article belongs to the Special Issue Wetland Biodiversity and Ecosystem Conservation)
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19 pages, 1106 KB  
Article
Clinical Prediction of Functional Decline in Multiple Sclerosis Using Volumetry-Based Synthetic Brain Networks
by Alin Ciubotaru, Alexandra Maștaleru, Thomas Gabriel Schreiner, Cristiana Filip, Roxana Covali, Laura Riscanu, Robert-Valentin Bilcu, Laura-Elena Cucu, Sofia Alexandra Socolov-Mihaita, Diana Lăcătușu, Florina Crivoi, Albert Vamanu, Ioana Martu, Lucia Corina Dima-Cozma, Romica Sebastian Cozma and Oana-Roxana Bitere-Popa
Life 2026, 16(3), 459; https://doi.org/10.3390/life16030459 - 11 Mar 2026
Viewed by 400
Abstract
Background: Disability progression in multiple sclerosis (MS) is increasingly recognized as a consequence of large-scale brain network disruption rather than isolated regional damage. Although diffusion tensor imaging (DTI) is the reference method for assessing structural connectivity, its limited availability restricts widespread clinical application. [...] Read more.
Background: Disability progression in multiple sclerosis (MS) is increasingly recognized as a consequence of large-scale brain network disruption rather than isolated regional damage. Although diffusion tensor imaging (DTI) is the reference method for assessing structural connectivity, its limited availability restricts widespread clinical application. There is therefore a critical need for alternative approaches capable of capturing network-level alterations using routinely acquired MRI data. Objective: This study aimed to determine whether synthetic structural connectivity matrices derived from standard regional volumetric MRI can capture clinically meaningful network alterations in MS and predict subsequent functional progression, particularly upper limb decline. Methods: Regional brain volumetry was obtained from routine T1-weighted MRI using an automated, clinically approved volumetric pipeline. Synthetic structural connectivity matrices were generated by integrating principles of structural covariance, distance-dependent connectivity, and disease-specific vulnerability patterns. Graph-theoretical network metrics were extracted to characterize global and regional topology. Machine learning models including logistic regression, support vector machines, random forests, and gradient boosting were trained to predict clinical progression defined by worsening on the 9-Hole Peg Test. Dimensionality reduction was performed using principal component analysis, and model performance was evaluated using balanced accuracy, AUC-ROC, and resampling-based validation. Feature importance analyses were conducted to identify network vulnerability patterns. Results: Synthetic connectivity networks exhibited biologically plausible properties, including preserved but attenuated small-world organization. Global efficiency showed a strong inverse correlation with disability severity (EDSS). Patients with clinical progression demonstrated marked reductions in network integration and segregation, alongside increased characteristic path length. Machine learning models achieved robust prediction of upper limb functional decline, with ensemble-based methods performing best (balanced accuracy > 80%, AUC-ROC up to 0.85). A limited subset of connections accounted for a disproportionate share of predictive power, predominantly involving frontoparietal associative networks, thalamocortical pathways, and inter-hemispheric connections. In a longitudinal subset, network-level alterations preceded measurable clinical deterioration by several months. Conclusions: Synthetic structural connectivity derived from routine volumetric MRI captures clinically relevant network-level disruption in multiple sclerosis and enables accurate prediction of functional progression. By bridging network neuroscience with widely accessible imaging data, this framework provides a pragmatic alternative for connectomic analysis when diffusion imaging is unavailable and supports a network-based understanding of disease evolution in MS. Full article
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17 pages, 3186 KB  
Article
Decoding the Liver–Blood Partitioning of Neonicotinoid Insecticides: Evidence from Paired Human Liver and Blood Biomonitoring
by Jiaqi Shao, Tingna Chen, Yihan Li, Wenfei Yu, Hangbiao Jin, Qinghua Zhou and Yuanchen Chen
Toxics 2026, 14(3), 237; https://doi.org/10.3390/toxics14030237 - 10 Mar 2026
Viewed by 571
Abstract
Neonicotinoids (NEOs) are among the most widely used insecticides worldwide, and their increasing detection in environmental and human matrices has raised concerns about chronic exposure and potential health risks. However, human data on target-organ burdens and liver–blood partitioning of NEOs remain unclear. Here, [...] Read more.
Neonicotinoids (NEOs) are among the most widely used insecticides worldwide, and their increasing detection in environmental and human matrices has raised concerns about chronic exposure and potential health risks. However, human data on target-organ burdens and liver–blood partitioning of NEOs remain unclear. Here, we quantified nine NEOs in paired liver tissue and whole-blood samples from 234 individuals to characterize internal distribution patterns and liver–blood partitioning of NEOs in humans. Samples included both liver cancer patients and non-liver cancer individuals, enabling exploratory evaluation of disease-related differences. At least one NEO was detected in 84.6% of blood samples and 87.2% of liver samples, with median concentrations ranging from 0.15–3.52 ng/mL in blood and 0.39–10.99 ng/g in liver, respectively. Dinotefuran was the most abundant compound in both matrices, accounting for 43.9% of total NEOs in blood and 25.8% in liver, indicating substantial matrix-specific compositional differences. Blood-to-liver partition ratios (R_B/L) varied substantially among compounds and showed a significant inverse association with logKow (p = 0.026), suggesting physicochemical property-dependent partitioning. R_B/L values were generally lower in liver cancer patients, indicating a relative shift toward hepatic accumulation. In exploratory logistic regression analyses, hepatic concentrations of acetamiprid, dinotefuran, imidaclothiz, and thiamethoxam remained statistically associated with liver cancer status after adjustment for covariates. Overall, these findings highlight the importance of tissue-specific biomonitoring and internal partitioning for interpreting human exposure to NEOs and for reducing exposure misclassification when evaluating liver-related health outcomes. Full article
(This article belongs to the Special Issue Identification of Emerging Pollutants and Human Exposure)
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23 pages, 2843 KB  
Article
Robust Multiblock STATICO for Modeling Environmental Indicator Structures: A Methodological Framework for Sustainability Monitoring in Complex Systems
by Harry Vite-Cevallos, Omar Ruiz-Barzola and Purificación Galindo-Villardón
Sustainability 2026, 18(5), 2607; https://doi.org/10.3390/su18052607 - 6 Mar 2026
Viewed by 335
Abstract
Sustainability monitoring relies on environmental indicator systems that integrate heterogeneous multivariate measurements across space and time; however, collinearity, non-Gaussian variability, and influential observations frequently destabilize classical multiblock methods and may bias indicator-based assessment and decision support. This study proposes a robust extension of [...] Read more.
Sustainability monitoring relies on environmental indicator systems that integrate heterogeneous multivariate measurements across space and time; however, collinearity, non-Gaussian variability, and influential observations frequently destabilize classical multiblock methods and may bias indicator-based assessment and decision support. This study proposes a robust extension of the STATICO (STATIS–CO-inertia) framework to model common structures among paired environmental indicator blocks under realistic data contamination. The approach preserves the original triadic algebraic formulation while incorporating robust covariance estimation and adaptive weighting to reduce the influence of outliers and structurally unstable blocks. Robustification is implemented at the interstructure stage through a reformulated Escoufier’s RV coefficient and in the construction of the compromise space via robust distances. The RV coefficient, a multivariate generalization of the squared Pearson correlation computed between cross-product matrices, is used to quantify structural similarity between paired data blocks and to evaluate the stability of the compromise structure. Performance is evaluated using simulated datasets calibrated to represent Ecuadorian coastal monitoring conditions. The results show that Robust STATICO increases compromise dominance and stability, redistributes inter-block similarities more coherently, and improves discriminative representation in the factorial space, yielding more interpretable and environmentally plausible structures. Overall, the proposed method provides a reliable analytical tool for sustainability-oriented environmental monitoring by supporting stable identification of persistent multivariate patterns and robust comparison of indicator structures in complex systems. Full article
(This article belongs to the Section Environmental Sustainability and Applications)
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27 pages, 6376 KB  
Article
A GAN-CNN Fusion Framework for Deep Learning-Based DOA Estimation in Low-SNR Environments
by Zhenshan Zhang, Wenjie Xu, Haitao Zou and Shichao Yi
Sensors 2026, 26(5), 1676; https://doi.org/10.3390/s26051676 - 6 Mar 2026
Viewed by 346
Abstract
Direction of Arrival (DOA) estimation faces significant performance degradation under low Signal-to-Noise Ratio (SNR) conditions, where traditional algorithms and deep learning models struggle due to corrupted spatial information and limited training data. To address these challenges, this paper introduces a novel two-stage framework [...] Read more.
Direction of Arrival (DOA) estimation faces significant performance degradation under low Signal-to-Noise Ratio (SNR) conditions, where traditional algorithms and deep learning models struggle due to corrupted spatial information and limited training data. To address these challenges, this paper introduces a novel two-stage framework that integrates a Generative Adversarial Network (GAN) for signal enhancement with a complex-valued Convolutional Neural Network (CNN) for DOA estimation. The proposed GAN incorporates an attention mechanism and a dedicated phase-consistent loss function to suppress noise while preserving spatial phase information critical for accurate direction finding. Enhanced signals are transformed into covariance matrices and processed by a complex-valued CNN designed to extract robust spatial features. Extensive experiments demonstrate that the proposed method achieves a DOA accuracy of 72.2% and a Root Mean Square Error (RMSE) of 3.9° at —10 dB SNR with 500 snapshots, substantially outperforming conventional and deep learning baselines. The framework also shows strong robustness to limited data, maintaining 93.8% accuracy with only 50 snapshots. The framework offers a practical solution for reliable DOA estimation in low-SNR and data-scarce environments. Full article
(This article belongs to the Section Remote Sensors)
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16 pages, 474 KB  
Article
Structural Equation Modeling of Genetic and Residual Covariance Matrices for Multiple-Trait Evaluation in Beef Cattle
by Marcos Jun-Iti Yokoo, Gustavo de los Campos, Vinícius Silva Junqueira, Fernando Flores Cardoso, Guilherme Jordão Magalhães Rosa and Lucia Galvão Albuquerque
Animals 2026, 16(5), 817; https://doi.org/10.3390/ani16050817 - 5 Mar 2026
Viewed by 310
Abstract
The continuous growth in both the number of phenotypic records and the range of traits included in beef cattle genetic evaluations poses substantial statistical and computational challenges for the estimation of genetic and residual (co)variance matrices required for breeding value estimation. Structural equation [...] Read more.
The continuous growth in both the number of phenotypic records and the range of traits included in beef cattle genetic evaluations poses substantial statistical and computational challenges for the estimation of genetic and residual (co)variance matrices required for breeding value estimation. Structural equation models (SEM), implemented using either factor analysis (FA) or recursive model (REC) structures, provide a flexible framework to model genetic and residual (co)variance matrices while yielding more parsimonious and computationally efficient parameterizations. Here, SEM was applied to estimate parameters for growth and ultrasound-measured carcass traits in beef cattle. The dataset comprised 2942 animals, and six traits were evaluated using standard multiple-trait mixed models (SMTM) and SEM. We considered FA and REC models implemented with six alternative parameterizations, in which random effects were represented as linear combinations of fewer unobservable random variables. Relative to the SMTM, both the model with two factors in the genetic covariance matrix (FA2G) and the model in which six recursive effects were constrained to zero in the residual covariance matrix (REC1) demonstrated a strong ability to capture genetic variability, as reflected by comparable heritability estimates. Correlations between estimated breeding values (EBV) for the same traits across models were consistently high, ranging from 0.94 to 1.00, indicating strong agreement among model estimates. The FA2G model was the most parsimonious in terms of the effective number of parameters (pD), with 431.2 pD, corresponding to a reduction of 25.3 parameters relative to the SMTM. The REC1 model also emerged as a competitive alternative for this dataset, exhibiting a lower pD (443.6) than the SMTM (456.5) and the most favorable deviance information criterion among all models evaluated (e.g., 37,868.6 for REC1 versus 37,874.7 for SMTM). Overall, these results demonstrate that mixed-effects multi-trait models for beef cattle genetic evaluation can be effectively implemented using FA or REC structures, which provide parsimonious representations of the underlying covariance patterns while maintaining high agreement in EBV. Full article
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22 pages, 1359 KB  
Article
Kernel VICReg for Self-Supervised Learning in Reproducing Kernel Hilbert Space
by M. Hadi Sepanj, Benyamin Ghojogh, Saed Moradi and Paul Fieguth
Big Data Cogn. Comput. 2026, 10(3), 78; https://doi.org/10.3390/bdcc10030078 - 5 Mar 2026
Viewed by 381
Abstract
Self-supervised learning (SSL) has emerged as a powerful paradigm for representation learning by optimizing geometric objectives, such as invariance to augmentations, variance preservation, and feature decorrelation, without requiring labels. However, most existing methods operate in Euclidean space, limiting their ability to capture nonlinear [...] Read more.
Self-supervised learning (SSL) has emerged as a powerful paradigm for representation learning by optimizing geometric objectives, such as invariance to augmentations, variance preservation, and feature decorrelation, without requiring labels. However, most existing methods operate in Euclidean space, limiting their ability to capture nonlinear dependencies and geometric structures. In this work, we propose Kernel VICReg, a novel self-supervised learning framework that pulls the VICReg objective into a Reproducing Kernel Hilbert Space (RKHS). By kernelizing each term of the loss, variance, invariance, and covariance, we obtain a general formulation that operates on double-centered kernel matrices and Hilbert–Schmidt norms, enabling nonlinear feature learning without explicit mappings. We demonstrate that Kernel VICReg mitigates the risk of representational collapse under challenging conditions and improves performance on datasets exhibiting nonlinear structure or limited sample regimes. Empirical evaluations across MNIST, CIFAR-10, STL-10, TinyImageNet, and ImageNet100 show consistent gains over Euclidean VICReg, with particularly strong improvements on datasets where nonlinear structures are prominent. UMAP visualizations are provided only as a qualitative illustration of embedding geometry and are not used as a calibration or statistical validation. Our results suggest that kernelizing SSL objectives is a promising direction for bridging classical kernel methods with modern representation learning. Full article
(This article belongs to the Section Artificial Intelligence and Multi-Agent Systems)
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26 pages, 12290 KB  
Article
State of Charge Estimation Method for Lithium-Ion Batteries Based on Online Parameter Identification and QPSO-AUKF
by Hai Guo, Zhaohui Li, Haoze Xue and Jing Luo
Batteries 2026, 12(3), 84; https://doi.org/10.3390/batteries12030084 - 1 Mar 2026
Viewed by 461
Abstract
Accurate estimation of the state of charge (SOC) is essential for the safe and efficient operation of lithium-ion batteries. Conventional Adaptive Unscented Kalman Filter (AUKF) methods often exhibit limited accuracy, primarily due to the empirical selection of process and measurement noise covariance matrices. [...] Read more.
Accurate estimation of the state of charge (SOC) is essential for the safe and efficient operation of lithium-ion batteries. Conventional Adaptive Unscented Kalman Filter (AUKF) methods often exhibit limited accuracy, primarily due to the empirical selection of process and measurement noise covariance matrices. To overcome this limitation, this study proposes a QPSO-AUKF algorithm based on a second-order RC equivalent circuit model, which integrates Quantum-behaved Particle Swarm Optimization (QPSO) with online parameter identification. In this approach, the QPSO algorithm optimizes the noise covariance matrices, which are subsequently used within the AUKF framework for SOC estimation. MATLAB R2020a simulations conducted on the Maryland and Wisconsin datasets demonstrate that the QPSO-AUKF reduces the root mean square error (RMSE) by more than 60% compared with the conventional AUKF, indicating a significant improvement in SOC estimation accuracy. Full article
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13 pages, 2529 KB  
Article
Insight into Genome-Wide Associations of Growth Trajectories Using a Hierarchical Non-Linear Mixed Model
by Ying Zhang, Li’ang Yang, Weiguo Cui and Runqing Yang
Biology 2026, 15(4), 361; https://doi.org/10.3390/biology15040361 - 20 Feb 2026
Viewed by 394
Abstract
In applying a hierarchical mixed model to genome-wide association analysis (GWAS) of longitudinal data, dimensionality reduction through modeling repeated measurements improves both computational efficiency and statistical power. Legendre polynomials can flexibly fit population growth trajectories, but higher orders substantially increase computational complexity. Instead [...] Read more.
In applying a hierarchical mixed model to genome-wide association analysis (GWAS) of longitudinal data, dimensionality reduction through modeling repeated measurements improves both computational efficiency and statistical power. Legendre polynomials can flexibly fit population growth trajectories, but higher orders substantially increase computational complexity. Instead of using Legendre polynomials, we first estimated fewer individual-specific parameters using biologically meaningful non-linear models and then associated these phenotypic regressions with genetic markers using a multivariate linear mixed model (mvLMM). After performing a canonical transformation of the regressions based on the pre-estimated covariance matrices under the null genomic mvLMM, we decomposed the mvLMM into mutually independent univariate models and incorporated EMMAX to enable rapid genome-wide mixed-model associations for each transformed phenotype. Simulations for longitudinal association analysis in maize and GWAS for the growth trajectories of body weights in mice demonstrated the advantages of hierarchical non-linear mixed models in computing efficiency and statistical power for detecting quantitative trait loci (QTL), compared with mvLMM for multiple growth points and the hierarchical random regression model using Legendre polynomials as sub-models. Full article
(This article belongs to the Section Bioinformatics)
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24 pages, 3411 KB  
Article
Radar Target Detection Within Nonhomogeneous Sea Clutter via MSP-MIG Detectors
by Jiayi Chen, Xiaoqiang Hua, Yongqiang Cheng, Hao Wu, Zheng Yang and Hongqiang Wang
Remote Sens. 2026, 18(4), 583; https://doi.org/10.3390/rs18040583 - 13 Feb 2026
Viewed by 387
Abstract
Subspace decomposition is a widely adopted approach for mitigating clutter interference in complex sea clutter scenarios. Based on the subspace decomposition principle, this paper expands the method to manifold space and presents a set of matrix information geometry (MIG) detectors with manifold subspace [...] Read more.
Subspace decomposition is a widely adopted approach for mitigating clutter interference in complex sea clutter scenarios. Based on the subspace decomposition principle, this paper expands the method to manifold space and presents a set of matrix information geometry (MIG) detectors with manifold subspace projection (MSP) for handling the target detection problem in nonhomogeneous sea clutter. According to the general method, the sample data are modeled as Hermitian positive-definite (HPD) matrices, and the clutter covariance matrix is estimated as the geometric mean of secondary HPD matrices. Through subspace projection, we map the HPD matrices onto a submanifold to enhance target–clutter separability. Three MSP-MIG detectors are put forward in line with different geometric measures. The experimental results show that our MSP-MIG detectors perform better than both traditional detectors and their non-MSP counterparts in nonhomogeneous sea clutter environment. Full article
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27 pages, 4240 KB  
Article
Robust State Estimation of Power System Based on Unscented Kalman Filter with Fractional-Order Adaptive Generalized Cross Correlation Entropy
by Yan Huang, Shangyong Wen, Hongyan Xin and Chaohui Xin
Mathematics 2026, 14(4), 642; https://doi.org/10.3390/math14040642 - 12 Feb 2026
Viewed by 324
Abstract
With the high penetration of power electronic devices, modern power systems exhibit complex fractional-order dynamic characteristics. Addressing this, along with the prevalent issues of multi-modal non-Gaussian noise, outliers, and sudden load changes, a fractional-order adaptive generalized cross correlation entropy unscented Kalman filter (FO-AGCCE-UKF) [...] Read more.
With the high penetration of power electronic devices, modern power systems exhibit complex fractional-order dynamic characteristics. Addressing this, along with the prevalent issues of multi-modal non-Gaussian noise, outliers, and sudden load changes, a fractional-order adaptive generalized cross correlation entropy unscented Kalman filter (FO-AGCCE-UKF) method is proposed in this paper. First, acknowledging that traditional integer-order models overlook the cumulative effects of historical states, a fractional-order (FO) discrete-time state-space model is constructed based on the Grünwald–Letnikov definition. This model accurately characterizes the long-memory and non-locality properties of power systems, thereby improving modeling accuracy during transient processes. Second, to mitigate the impact of non-Gaussian noise and outliers, the generalized cross correlation entropy (GCCE) criterion is adopted to replace the traditional mean square error (MSE) criterion. Combined with statistical linearization techniques, a novel recursive filtering framework is derived to enhance robustness against heavy-tailed noise. Furthermore, to address the time-varying and unknown statistical properties of process and measurement noise, an adaptive update mechanism for noise covariance matrices is introduced, which corrects noise parameters online based on innovation sequences. Simulation experiments and comparative analysis on multiple power systems of different scales demonstrate that the proposed method not only exhibits superior anti-interference capability in mixed-Gaussian noise environments but also achieves a faster convergence speed and higher tracking accuracy during dynamic events such as sudden load changes. Full article
(This article belongs to the Special Issue Fractional Order Systems and Its Applications)
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26 pages, 5240 KB  
Article
Enhanced Assumption-Aware Linear Discriminant Analysis for the Wisconsin Breast Cancer Dataset: A Guide to Dimensionality Reduction and Prediction with Performance Comparable to Machine Learning Methods
by Vasiliki Pantoula, Vasileios Mandikas and Tryfon Daras
AppliedMath 2026, 6(2), 20; https://doi.org/10.3390/appliedmath6020020 - 3 Feb 2026
Viewed by 438
Abstract
The analysis of multivariate data is a central issue in biomedical research, where the accurate classification of patients and the extraction of reliable conclusions are of critical importance. Linear Discriminant Analysis (LDA) remains one of the most established methods for both dimensionality reduction [...] Read more.
The analysis of multivariate data is a central issue in biomedical research, where the accurate classification of patients and the extraction of reliable conclusions are of critical importance. Linear Discriminant Analysis (LDA) remains one of the most established methods for both dimensionality reduction and classification of data. In this paper, we examine in detail the theoretical foundations, assumptions, and statistical properties of LDA, and apply the method step by step to real data from the Breast Cancer Wisconsin (Diagnostic) database, which includes cellular features from breast biopsy samples with the aim of distinguishing benign from malignant tumors. Emphasis is placed on the importance of the method’s assumptions, such as multivariate normality, equality of covariance matrices, and absence of multicollinearity, demonstrating that their fulfillment leads to significant improvements in model performance. Specifically, careful preprocessing and strict adherence to these assumptions increase classification accuracy from 95.6% (94.7% cross-validated) to 97.8% (97.4% cross-validated). To our knowledge, this study is the first to demonstrate the dual use of LDA as both a dimensionality-reduction tool and a predictive classification model for this medical database within the same biomedical analysis framework. Moreover, we provide, for the first time, a systematic comparison between our assumption-aware LDA model and related studies employing the most accurate machine-learning classifiers reported in the literature for this dataset, showing that classical LDA achieves accuracy comparable to these more complex methods. The resulting discriminant model, which uses 13 variables out of the original 30, can be applied easily by clinical researchers to classify new cases as benign or malignant, while simultaneously providing interpretable coefficients that reveal the underlying relationships among variables. The implementation is carried out in the SPSS environment, following the theoretical steps described in the paper, thus offering a user-friendly and reproducible framework for reliable application. In addition, the study establishes a structured and transparent workflow for the proper application of LDA in biomedical research by explicitly linking assumption verification, preprocessing, dimensionality reduction, and classification. Full article
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16 pages, 2156 KB  
Article
An Adaptive Extended Kalman Filter with Passive Control for DC-DC Converter Supplying Constant Power and Constant Voltage Loads
by Peng Wang, Zhenlong Ma, Junfeng Tian, Zhe Li, Yani Li, Panbao Wang and Yang Zhou
Energies 2026, 19(3), 682; https://doi.org/10.3390/en19030682 - 28 Jan 2026
Viewed by 268
Abstract
This article introduces an integrated control scheme combining an Adaptive Extended Kalman Filter (AEKF) with a Passivity-Based Control (PBC) approach to stabilize a DC-DC boost converter feeding both constant voltage and constant power loads (CPLs) in DC microgrids. Unlike conventional observers, the AEKF [...] Read more.
This article introduces an integrated control scheme combining an Adaptive Extended Kalman Filter (AEKF) with a Passivity-Based Control (PBC) approach to stabilize a DC-DC boost converter feeding both constant voltage and constant power loads (CPLs) in DC microgrids. Unlike conventional observers, the AEKF adapts its covariance matrices in real time to accurately estimate both system states and the unknown load dynamics introduced by CPLs, thereby eliminating the need for additional sensors and enhancing estimation convergence. Coupled with the PBC, the estimated disturbances are compensated via a feedforward path, significantly improving the system’s resilience to input voltage fluctuations and load variations. Through a Lyapunov-based stability analysis, the combined strategy is proven to ensure large-signal stability while maintaining a rapid transient recovery profile, even under significant parametric uncertainties. The simulation of this algorithm was implemented using PLECS, thoroughly validating the effectiveness and robustness of the proposed method. Full article
(This article belongs to the Special Issue Control and Optimization of Power Converters)
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25 pages, 1524 KB  
Article
VQF-Based Decoupled Navigation Architecture for High-Curvature Maneuvering of Underwater Vehicles
by Bowei Cui, Yu Lu, Lei Zhang, Fengluo Chen, Bingchen Liang, Peng Yao, Xiaokai Mu and Shimin Yu
Sensors 2026, 26(3), 814; https://doi.org/10.3390/s26030814 - 26 Jan 2026
Viewed by 422
Abstract
To mitigate the position divergence resulting from attitude error amplification in conventional fully coupled architectures, this study proposes a decoupled navigation architecture based on the Versatile Quaternion-based Filter (VQF). This architecture removes attitude estimation from the state vector, forming a two-layer structure comprising [...] Read more.
To mitigate the position divergence resulting from attitude error amplification in conventional fully coupled architectures, this study proposes a decoupled navigation architecture based on the Versatile Quaternion-based Filter (VQF). This architecture removes attitude estimation from the state vector, forming a two-layer structure comprising an independent attitude module and a navigation filter. The VQF is integrated as a standalone attitude module via a standardized interface. An uncertainty quantification model is developed by extracting the VQF’s internal correction states, which maps deviations among intermediate quaternion values to a measurable uncertainty metric. To compensate for the loss of cross-covariance induced by decoupling, a dual-layer compensation mechanism is introduced: a base layer adjusts the overall uncertainty using innovation statistics, while a compensation layer explicitly propagates attitude uncertainty through parameterized noise matrices. Experimental results demonstrate that the proposed method achieves notable improvements in positioning accuracy and significantly suppresses extreme errors in high-curvature scenarios. The approach is particularly effective for high-curvature, high-dynamic applications where process noise modeling is inherently difficult. Compared to traditional fully coupled architectures, the decoupled architecture offers enhanced robustness. The complementary characteristics identified between the two architectures provide valuable insights for expanding the operational envelope of underwater navigation systems. Full article
(This article belongs to the Section Navigation and Positioning)
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16 pages, 758 KB  
Article
Optimization of Working Capital for Financial Sustainability in Manufacturing Companies: A Statistical Model
by Karla Estefanía Morales, Edison Roberto Valencia-Nuñez, Josselyn Paredes-León and Freddy Armijos-Arcos
J. Risk Financial Manag. 2026, 19(1), 85; https://doi.org/10.3390/jrfm19010085 - 21 Jan 2026
Viewed by 698
Abstract
Background: Working capital management plays a critical role in ensuring business liquidity and financial sustainability. However, few studies in developing economies have employed multivariate statistical techniques to optimize working capital decisions. This study addresses this gap by applying discriminant analysis to classify Ecuadorian [...] Read more.
Background: Working capital management plays a critical role in ensuring business liquidity and financial sustainability. However, few studies in developing economies have employed multivariate statistical techniques to optimize working capital decisions. This study addresses this gap by applying discriminant analysis to classify Ecuadorian manufacturing firms according to their financial sustainability and business continuity. Methods: A quantitative approach was applied to a sample of 112 manufacturing companies located in Zone 3 of Ecuador, covering the 2017–2020 period. The model incorporated working capital indicators and the Z-Score index as independent variables, while company size served as the categorical dependent variable. Results: The discriminant function retained two significant predictors—Working Capital (2019) and Z-Score (2017)—with an eigenvalue of 0.191, a canonical correlation of 0.400, and an overall classification accuracy of 71.4%. Box’s M test (p = 0.000) indicated unequal covariance matrices, suggesting cautious interpretation but acceptable robustness of the model. Conclusions: This study concludes that working capital and Z-Score are effective indicators for assessing financial sustainability and predicting firm continuity. The findings provide practical insights for managers and policymakers to enhance financial efficiency and resource allocation. The originality of this work lies in the application of discriminant analysis to model financial sustainability in Ecuador’s manufacturing sector, offering a statistical foundation for future optimization models. Full article
(This article belongs to the Section Sustainability and Finance)
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