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13 pages, 1940 KB  
Perspective
Contemporary and Future Perspectives on Thoracic Trauma Care: Surgical Stabilization, Multidisciplinary Approaches, and the Role of Artificial Intelligence
by Chiara Angeletti, Gino Zaccagna, Maurizio Vaccarili, Giulia Salve, Andrea De Vico, Alessandra Ciccozzi and Duilio Divisi
J. Clin. Med. 2025, 14(22), 8041; https://doi.org/10.3390/jcm14228041 - 13 Nov 2025
Viewed by 211
Abstract
Background/Objectives: Thoracic trauma remains a leading cause of trauma-related illness and death. Despite advances in imaging, ventilation strategies, and surgical fixation, its management remains a topic of debate, with varying practices across hospitals. Current Gaps: Although surgical stabilization of rib fractures (SSRF) has [...] Read more.
Background/Objectives: Thoracic trauma remains a leading cause of trauma-related illness and death. Despite advances in imaging, ventilation strategies, and surgical fixation, its management remains a topic of debate, with varying practices across hospitals. Current Gaps: Although surgical stabilization of rib fractures (SSRF) has shown a mortality benefit in cases of flail chest and in elderly patients, its indications for non-flail cases remain uncertain. Analgesia strategies are evolving, and epidural remains the gold standard; however, it is limited by contraindications. In contrast, regional blocks, such as the erector spinae plane block (ESPB) and serratus anterior plane block (SAPB), are emerging as safer alternatives to opioid and thoracic epidural analgesia (TEA). Artificial intelligence (AI) is transforming imaging interpretation and risk stratification; however, its integration into daily trauma care is still in its early stages of development. Perspective: This article examines the integration of surgical innovation, regional anesthesia, and AI-powered diagnostics as integral components of future thoracic trauma care. We emphasize the importance of standardized surgical criteria, multimodal pain management approaches, and AI-assisted decision-making tools. Conclusions: Thoracic trauma care is shifting toward a personalized, multidisciplinary, and technology-enhanced approach. Incorporating evidence-based SSRF, advanced pain management techniques, and AI-supported imaging can help reduce mortality, enhance recovery, and optimize resource utilization. Full article
(This article belongs to the Special Issue Clinical Update on Thoracic Trauma)
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14 pages, 734 KB  
Article
Skeletal Muscle Quality Evaluation for Prognostic Stratification in the Emergency Department of Patients ≥65 Years with Major Trauma
by Marcello Covino, Luigi Carbone, Martina Petrucci, Gabriele Pulcini, Marco Cintoni, Luigi Larosa, Andrea Piccioni, Gianluca Tullo, Davide Antonio Della Polla, Benedetta Simeoni, Mariano Alberto Pennisi, Antonio Gasbarrini, Maria Cristina Mele and Francesco Franceschi
J. Clin. Med. 2025, 14(21), 7504; https://doi.org/10.3390/jcm14217504 - 23 Oct 2025
Viewed by 237
Abstract
Background: In patients aged 65 years and older who experience severe trauma, their underlying health status significantly influences overall mortality. This study aimed to determine whether computed tomography (CT) evaluation of skeletal muscle quality could serve as an effective risk stratification tool in [...] Read more.
Background: In patients aged 65 years and older who experience severe trauma, their underlying health status significantly influences overall mortality. This study aimed to determine whether computed tomography (CT) evaluation of skeletal muscle quality could serve as an effective risk stratification tool in the emergency department (ED) for this population. Methods: Retrospective observational study conducted between January 2018 and September 2021, including consecutive patients ≥65 years admitted to the ED for a major trauma (defined as having an Injury Severity Score > 15). Muscle quality analysis was made by specific software (Slice-O-Matic v5.0, Tomovision®, Montreal, QC, Canada) on a CT-scan slice at the level of the third lumbar vertebra (L3). Results: A total of 263 patients were included (72.2% males, median age 76 (71–82)), of whom 88 (33.5%) died during hospitalization. The deceased patients had a significantly lower skeletal muscle area density (SMAd) compared with survivors. The multivariate Cox regression analysis confirmed that SMAd <38 at the ED admission was an independent risk for death (adjusted HR 1.68 [1.1–2.7]). The analysis also revealed that, among the survivors after the first week of hospitalization, the patients with low SMAd had an increased risk of death (adjusted HR 3.12 [1.2–7.9]). Conclusions: Skeletal muscle density assessed by a CT scan at ED admission may represent a valuable prognostic marker for risk stratification patients ≥65 years with major trauma. In patients with SMAd <38 HU the in-hospital mortality risk could be particularly increased after the first week of hospitalization. Full article
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24 pages, 1316 KB  
Article
When Pedestrian Crossings Become Danger Zones: Trauma and Mortality Risks in Elderly Pedestrians
by Peter Pavol, Vasileios Topalis, Sofia-Chrysovalantou Zagalioti, Olha Kuzyo, Martin Müller, Aristomenis K. Exadaktylos, Mairi Ziaka and Jolanta Klukowska-Rötzler
Int. J. Environ. Res. Public Health 2025, 22(10), 1556; https://doi.org/10.3390/ijerph22101556 - 13 Oct 2025
Viewed by 545
Abstract
Aim: Older adult pedestrians are at greater risk of severe injuries than younger pedestrians due to gradual physical changes and coexisting medical conditions. This leads to longer hospital stays, increased mortality risk, and higher inpatient costs. Focusing on the aging population, this study [...] Read more.
Aim: Older adult pedestrians are at greater risk of severe injuries than younger pedestrians due to gradual physical changes and coexisting medical conditions. This leads to longer hospital stays, increased mortality risk, and higher inpatient costs. Focusing on the aging population, this study explores the characteristics and injury profiles of pedestrian crossing accidents in the capital city of Bern, Switzerland. Methods: Our retrospective cohort study comprised adult patients admitted to our ED between 1 January 2013 and 31 December 2023, as crossing (or zebra crossing)-related pedestrian victims. Two cohorts were formed on the basis of age < 65 and ≥65 years and compared according to the setting of the accident, type, pattern of the injury, and clinical outcomes (short-term mortality, ICU/hospital length of stay). Results: Of a total of 124 patients, 31.5% (n = 39) of patients were elderly (65+ group). In contrast to the younger patients, the aging population was predominantly admitted as inpatients (64.1% vs. 35.3%, p = 0.001) and was hospitalised in the intensive care unit (20.5% vs. 6%, p = 0.020). Older patients were more likely to be polytraumatised (41% vs. 11.8%, p = 0.001) and to have been tossed or hurled than patients under 65 years (75% vs. 47.3%, p = 0.016). Fractures of the upper extremities (17.9% vs. 4.7%, p = 0.016), pelvis (30.8% vs. 9.4%, p = 0.003), and thoracic spine (12.8% vs. 2.4%, p = 0.019) were significantly more common in the elderly population. Intracranial haemorrhage (35.9% vs. 17.6%, p = 0.026), abdominal trauma (17.9% vs. 5.9%, p = 0.035), and relevant vessel damage (30.8% vs. 3.5%, p < 0.001) were also significantly higher in geriatric patients. Trauma indices were slightly more increased in the older population than in the younger group (ISS; p = 0.004 and AIS > 2 of chest and thoracic spine; abdomen, pelvic contents, and lumbar spine; extremities & bony pelvis p < 0.05). The 65+ group had a longer length of hospital stay (p = 0.001) and ICU stay (p = 0.002). A hospital stay longer than 7 days was also significantly more common in elderly individuals (p = 0.007). In-hospital (15.4% vs. 1.2%, p = 0.001) and 30-day mortality (17.9% vs. 1.2%, p < 0.001) were significantly higher in patients over 65 years of age. Conclusion: In our study, the impact of pedestrian crossing accidents was more severe in the elderly, as indicated by the severity of injuries, hospitalisation rate, longer length of hospital and ICU stays, and higher mortality rates. These findings underline the importance of developing tailored strategies to reduce crosswalk accidents and to optimise management approaches for these vulnerable patients. Full article
(This article belongs to the Special Issue Road Traffic Risk Assessment: Control and Prevention of Collisions)
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14 pages, 730 KB  
Article
Surgical Outcomes of Craniocervical Junction Fractures in Elderly Patients: A Retrospective Single-Center Series
by Nicola Montemurro, Stefano Carnesecchi, Riccardo Morganti, Antonella De Carlo and Ardico Cocciaro
J. Pers. Med. 2025, 15(10), 485; https://doi.org/10.3390/jpm15100485 - 10 Oct 2025
Viewed by 536
Abstract
Background: Fractures of the first and second cervical vertebrae are common in both young and elderly patients. Surgical management of C1–C2 fractures in elderly patients is controversial. The aim of this study is to report the rate of fusion in elderly patients who [...] Read more.
Background: Fractures of the first and second cervical vertebrae are common in both young and elderly patients. Surgical management of C1–C2 fractures in elderly patients is controversial. The aim of this study is to report the rate of fusion in elderly patients who underwent surgery for C1 or C2 fractures. Methods: A retrospective review of all patients over the age of 65 years old who underwent surgical treatment for C1 or C2 fracture was reported. Visual analog scale (VAS) and neck disability index (NDI) were used to assess patients’ clinical outcome at 1 year follow-up. Cervical spine computer tomography (CT) scans were performed in all cases before surgery and at 1 year follow-up to evaluate the long-term postoperative rate of fusion, according to Lenke fusion grade. Results: From 2019 to 2023, 105 patients with cervical craniocervical junction (CCJ) fracture underwent surgical treatment in our Pisana University Hospital. Among all these, 74 patients (70.5%) were over 65 years old. The mean age of the study population was 76.9 years old (12.2% aged 65–70, 51.4% aged 70–79, and 36.5% over 80). According to the AO Spine Upper Cervical Injury Classification System, 6 (8.1%) patients presented a type II fracture and 68 (91.9%) patients presented a type III fracture. At admission, neurological examination resulted in American Spinal Injury Association (ASIA) E in 97.3% of cases. Over 60% of all patients underwent C1–C2 posterior fixation. Postoperative complications occurred in 12.25% of patients. According to the criteria described by Lenke, a good rate of fusion (A-B grade) was obtained in 71.6% of patients. Conclusions: In elderly patients with CCJ fractures, precision medicine can help identify those at higher risk for complications and guide personalized treatment strategies. Surgical treatment of CCJ fractures in elderly patients, although not always associated with bone fusion, can be performed with an acceptable incidence of mortality and morbidity, allowing rapid mobilization and return to pre-trauma levels of independence. Full article
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12 pages, 2387 KB  
Article
Impact of CT-Defined Sarcopenia on Clinical Outcomes in Elderly Trauma Patients: A Retrospective Korean Cohort Study
by Juhong Park, Yesung Oh, Songhee Kwon, Jihyun Lee, Mihyang Kim, Donghwan Choi and Junsik Kwon
Healthcare 2025, 13(18), 2321; https://doi.org/10.3390/healthcare13182321 - 16 Sep 2025
Viewed by 483
Abstract
Background/Objectives: Sarcopenia, the age-related decline in skeletal muscle mass and function, is increasingly recognized as an important prognostic factor among elderly patients. This study aimed to evaluate whether computed tomography (CT)-defined sarcopenia independently predicts short-term mortality in elderly Korean trauma patients. Methods: We [...] Read more.
Background/Objectives: Sarcopenia, the age-related decline in skeletal muscle mass and function, is increasingly recognized as an important prognostic factor among elderly patients. This study aimed to evaluate whether computed tomography (CT)-defined sarcopenia independently predicts short-term mortality in elderly Korean trauma patients. Methods: We retrospectively analyzed 722 patients aged ≥65 years admitted to a Korean Level I trauma center between January 2020 and December 2021. Sarcopenia was defined as the lowest sex-specific quartile of skeletal muscle index (SMI) measured at the third lumbar vertebra (L3) within 7 days of admission. Demographics, injury severity, and outcome variables were compared between groups. Kaplan–Meier survival analysis with a 24 h landmark and multivariable Cox regression were applied to identify independent predictors of 30-day mortality. Results: Among 722 patients, 181 (25.1%) were sarcopenic. They were older and had lower body mass index and serum albumin yet showed lower Injury Severity Score (ISS) at presentation. Despite this, in-hospital mortality was higher in sarcopenic patients (15.5% vs. 9.8%, p = 0.036), while 24 h mortality did not differ (4.4% vs. 3.7%, p = 0.663). Landmark analysis starting at 24 h demonstrated significantly worse 30-day survival in the sarcopenia group (log-rank p = 0.028). Multivariable Cox regression confirmed sarcopenia as an independent predictor of 30-day mortality (HR, 2.36; 95% CI, 1.07–5.23; p = 0.034), along with higher ISS and lower Glasgow Coma Scale (GCS) scores. Conclusions: CT-defined sarcopenia at the L3 level independently predicts 30-day mortality in elderly trauma patients and may support early risk stratification. Full article
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8 pages, 757 KB  
Case Report
Hyponatremia Due to VZV-Induced SIADH in an Older Patient: Case Report and Literature Review
by Zuzanna Żak-Skryśkiewicz, Patrycja Krupińska, Carlo Bieńkowski and Przemysław Witek
Infect. Dis. Rep. 2025, 17(5), 106; https://doi.org/10.3390/idr17050106 - 30 Aug 2025
Viewed by 894
Abstract
Introduction: Hyponatremia is a common finding in hospitalized patients, especially the elderly. Symptoms of hyponatremia can vary depending on the concentration of sodium in serum as well as the dynamics of its escalation. Hyponatremia can have many etiologies, including medication, vomiting, or diarrhea, [...] Read more.
Introduction: Hyponatremia is a common finding in hospitalized patients, especially the elderly. Symptoms of hyponatremia can vary depending on the concentration of sodium in serum as well as the dynamics of its escalation. Hyponatremia can have many etiologies, including medication, vomiting, or diarrhea, and central nervous system disorders, including tumors, trauma, and infections. Case report: In this case, we present a 74-year-old patient who was admitted to the Department of Internal Medicine with symptomatic, acute, and severe hyponatremia in the course of the syndrome of inappropriate antidiuretic hormone secretion due to varicella zoster virus meningoencephalitis. Clinical improvement and normalization of natremia occurred after the initiation of causal treatment. Conclusion: Given the complexity of the potential causes of hyponatremia and the variety of treatments available, it is essential to thoroughly consider the possible reasons for electrolyte abnormalities, including uncommon ones such as central nervous system infections. Full article
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10 pages, 1321 KB  
Article
Investigation of the Medium- and Long-Term Results of a Pioneering Method in the Treatment of Geriatric Intertrochanteric Femur Fractures: Osteosynthesis Using the WALANT Technique
by Yusuf Murat Altun, Mete Gedikbaş and Murat Aşçı
J. Clin. Med. 2025, 14(17), 6078; https://doi.org/10.3390/jcm14176078 - 28 Aug 2025
Viewed by 650
Abstract
Background/Objectives: Femoral neck and proximal femur fractures in the elderly can result from low-energy trauma due to osteoporotic changes and contribute significantly to increased morbidity and mortality. Despite various treatment options, closed reduction and internal fixation (CRIF) with intramedullary nails has become [...] Read more.
Background/Objectives: Femoral neck and proximal femur fractures in the elderly can result from low-energy trauma due to osteoporotic changes and contribute significantly to increased morbidity and mortality. Despite various treatment options, closed reduction and internal fixation (CRIF) with intramedullary nails has become the predominant approach. While a minimally invasive approach reduces complications and speeds recovery, this outcome is not always feasible in practice. The primary surgical goal remains achieving a stable and precise fracture reduction, favoring CRIF when possible. Our study aims to evaluate the clinical, radiological, and functional outcomes of patients operated on using the Wide-Awake Local Anesthesia No Tourniquet (WALANT) technique. Methods: Patients who underwent surgery for intertrochanteric femur fractures between June 2019 and June 2021 were analyzed. Patients who were between 75 and 90 years old and had undergone surgery with a proximal femoral nail (PFN) were included in the study. Patients were excluded if they required general anesthesia, if an acceptable reduction could not be achieved with the PFN, if they did not attend the last follow-up examination, or if the follow-up period was <4 years. Patients were functionally assessed using the Harris hip score at the 6th month and at the last follow-up and using the visual analog scale at the surgery, at the 4th hour after surgery, and at the time of discharge. For radiological assessment, the classification of reduction quality and the measurement of the tip–apex distance were used. Results: Forty patients (22F/18M) were included in the study. Their mean age was 83.0 ± 2.9 years. The mean time from trauma to surgery was 6.8 ± 2.3 h. Patients were mobilized on average 1.53 ± 0.8 h after surgery, and the mean hospitalization time was 27.4 ± 8.1 h. No statistically significant decrease in hemoglobin value was observed before or after surgery (p = 0.476). The Harris hip score was 73.3 ± 3.2 at the 6th month postoperatively and 74.9 ± 2.5 at the last follow-up (p = 0.296). The reduction quality was found to be poor in only two patients. Conclusions: The WALANT technique’s promising results in terms of pain management, blood loss control, and early mobilization show that it is a viable alternative to conventional anesthesia methods in geriatric hip fractures. Full article
(This article belongs to the Section Orthopedics)
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8 pages, 1201 KB  
Article
Collaboration and Innovation: A Bibliometric Study of the Rise in MMA Embolization in Neurosurgery
by Jagoš Golubović, Igor Horvat, Djula Djilvesi, Bojan Jelača and Petar Vuleković
Clin. Transl. Neurosci. 2025, 9(3), 38; https://doi.org/10.3390/ctn9030038 - 25 Aug 2025
Viewed by 681
Abstract
Chronic subdural hematoma (cSDH) is a common neurosurgical condition in the elderly, often resulting from minor head trauma. Traditional surgical treatments such as burr-hole drainage carry recurrence rates of 10–20% and significant risks in older patients, especially those on anticoagulation therapy. Middle meningeal [...] Read more.
Chronic subdural hematoma (cSDH) is a common neurosurgical condition in the elderly, often resulting from minor head trauma. Traditional surgical treatments such as burr-hole drainage carry recurrence rates of 10–20% and significant risks in older patients, especially those on anticoagulation therapy. Middle meningeal artery (MMA) embolization has emerged as a minimally invasive alternative, aiming to reduce blood flow to the dura and thereby promote hematoma resolution and lower recurrence. We conducted a bibliometric analysis of publications on MMA embolization for cSDH up to December 2023. The analysis shows a sharp increase in research activity over the past decade. North America, Japan, and Europe are leading contributors, with collaborative networks forming among major institutions. Key journals in neurosurgery and neurointervention have published much of this research, and author collaborations are extensive. Frequently used keywords such as “recurrence” and “treatment outcome” reflect an emphasis on reducing rebleeding and improving patient outcomes. In conclusion, MMA embolization is rapidly gaining attention as a promising treatment for cSDH. While early results are favorable and multi-center efforts are expanding the evidence base, further research is needed to establish long-term efficacy, optimize patient selection, and standardize techniques. Full article
(This article belongs to the Section Endovascular Neurointervention)
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15 pages, 2582 KB  
Review
Use of Integra® Dermal Regeneration Template Bilayer in Burn Reconstruction: Narrative Review, Expert Opinion, Tips and Tricks
by Clemens Maria Schiestl, Naiem Moiemen, Patrick Duhamel, Isabel Jones, Marcello Zamparelli, Juan Carlos López-Gutiérrez and Simon Kuepper
Eur. Burn J. 2025, 6(3), 45; https://doi.org/10.3390/ebj6030045 - 18 Aug 2025
Viewed by 1725
Abstract
Burn injuries remain a complex clinical challenge, particularly in reconstructive settings where donor sites are limited. Integra® Dermal Regeneration Template (IDRT), a bilayer dermal substitute, facilitates neodermis formation and supports functional and aesthetic recovery following burn trauma. This narrative review and expert [...] Read more.
Burn injuries remain a complex clinical challenge, particularly in reconstructive settings where donor sites are limited. Integra® Dermal Regeneration Template (IDRT), a bilayer dermal substitute, facilitates neodermis formation and supports functional and aesthetic recovery following burn trauma. This narrative review and expert opinion synthesizes current literature and clinical experience on the application of IDRT in post-burn reconstruction. It discusses the biological mechanism of dermal regeneration, surgical protocols including wound bed preparation and grafting, and considerations for anatomical regions such as the face, torso, and limbs. The review emphasizes key factors influencing successful outcomes, including patient selection, timing, and multidisciplinary coordination. Potential complications, such as infection, hematoma, and poor graft adherence, are addressed along with prevention and management strategies. Special considerations for pediatric and elderly populations are also highlighted. Through evidence-based insights and illustrative case examples, this review aims to inform surgical decision-making and promote best practices in reconstructive burn care using IDRT. Full article
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11 pages, 222 KB  
Perspective
Odontophobia Across the Lifespan: Clinical Perspectives, Vulnerable Populations, and Inclusive Strategies for Dental Anxiety Management
by Antonio Fallea, Simona L’Episcopo, Aurora Palmigiano, Giuseppe Lanza and Raffaele Ferri
J. Clin. Med. 2025, 14(16), 5766; https://doi.org/10.3390/jcm14165766 - 14 Aug 2025
Cited by 1 | Viewed by 868
Abstract
Odontophobia, defined as the intense and persistent fear of dentists or dental care, is a widely underestimated, yet clinically significant, barrier to oral health. It affects individuals across all age groups, from children to the elderly, and is particularly prevalent among those with [...] Read more.
Odontophobia, defined as the intense and persistent fear of dentists or dental care, is a widely underestimated, yet clinically significant, barrier to oral health. It affects individuals across all age groups, from children to the elderly, and is particularly prevalent among those with intellectual or developmental disabilities. Odontophobia is a multifactorial condition influenced by psychological, sensory, cognitive, and sociocultural factors. Left unaddressed, it contributes to poor oral health outcomes, avoidant behavior, and broader health disparities. This perspective paper explores the clinical manifestations and principles of management of odontophobia across populations and different age groups, highlighting the limitations of pharmacological sedation, especially when used in isolation. Instead, evidence supports the use of cognitive behavioral strategies, desensitization protocols, sensory-adaptive environments, and communication-based approaches, such as the “tell-show-do” method. Innovative technologies, including virtual reality, offer additional promise. This paper also addresses critical gaps in the research, the paucity of tailored interventions for vulnerable groups, and both ethical and legal complexities surrounding consent, autonomy, and equitable access. Ultimately, managing odontophobia requires a shift toward “person-centered” and “trauma-informed” dental care, supported by interdisciplinary collaboration, inclusive infrastructure, and policy-level commitment to reduce fear-based disparities in oral health. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
13 pages, 229 KB  
Review
Rib Fractures and Surgical Stabilization: A Narrative Review of Contemporary Management and Outcomes
by Juan F. Figueroa and Susana Fortich
Trauma Care 2025, 5(3), 19; https://doi.org/10.3390/traumacare5030019 - 12 Aug 2025
Viewed by 4038
Abstract
Background: Rib fractures are among the most common thoracic injuries following blunt trauma and are associated with significant morbidity, particularly in elderly and polytrauma populations. Historically managed non-operatively, recent advances have redefined the role of surgical stabilization of rib fractures (SSRF) in improving [...] Read more.
Background: Rib fractures are among the most common thoracic injuries following blunt trauma and are associated with significant morbidity, particularly in elderly and polytrauma populations. Historically managed non-operatively, recent advances have redefined the role of surgical stabilization of rib fractures (SSRF) in improving patient outcomes. The objective of this narrative review is to evaluate current evidence surrounding the management of rib fractures, with a focus on indications for SSRF, surgical techniques, special populations, and future directions in care. Methods: A narrative review of the literature was conducted, incorporating relevant randomized controlled trials, cohort studies, clinical guidelines, and expert consensus statements. Emphasis was placed on patient selection criteria, surgical strategies, multimodal analgesia, and emerging technologies. Results: SSRF has demonstrated benefits in short- and long-term outcomes, including improved pain control, reduced ventilator dependence, shorter ICU and hospital stays, and better functional recovery. These outcomes are most evident in patients with flail chest, severe displacement, or failure of conservative therapy. Minimally invasive techniques and 3D-printed implants represent promising innovations. Despite growing evidence, SSRF remains underutilized due to variability in institutional protocols and access to trained personnel. Conclusions: The management of rib fractures continues to evolve with increasing support for surgical intervention in select patients. Wider implementation of SSRF, guided by standardized protocols and advanced technologies, may improve outcomes and reduce complications in this high-risk trauma population. Full article
11 pages, 1585 KB  
Article
Age-Related Patterns of Midfacial Fractures in a Hungarian Population: A Single-Center Retrospective Study
by Enikő Orsi, Lilla Makszin, Zoltán Nyárády, Lajos Olasz and József Szalma
J. Clin. Med. 2025, 14(15), 5396; https://doi.org/10.3390/jcm14155396 - 31 Jul 2025
Viewed by 487
Abstract
Background: Midfacial fractures are common outcomes of facial trauma. While younger individuals typically sustain these injuries through high-energy events like assaults and traffic or sports accidents, elderly patients increasingly present with fractures from low-energy mechanisms, primarily falls. Purpose: The aim of this study [...] Read more.
Background: Midfacial fractures are common outcomes of facial trauma. While younger individuals typically sustain these injuries through high-energy events like assaults and traffic or sports accidents, elderly patients increasingly present with fractures from low-energy mechanisms, primarily falls. Purpose: The aim of this study was to analyze age- and gender-specific patterns in midfacial fractures over a 10-year period, with emphasis on elderly individuals and low-energy trauma. Methods: A retrospective review was performed of proven midfacial fractures between 2013 and 2022 at the Department of Oral and Maxillofacial Surgery (University of Pécs, Hungary). The patients were stratified by age (<65 vs. ≥65 years) and gender. The variables included the injury mechanism, fracture localization, the dental status, hospitalization, and the presence of associated injuries. Bivariate analyses were performed, and the significance level was set to p < 0.05. Results: A total of 957 radiologically confirmed midfacial fracture cases were evaluated, of whom 344 (35.9%) were ≥65 years old. In the elderly group, females had a 19-fold higher risk for midfacial trauma than younger females (OR: 19.1, 95%CI: 9.30–39.21). In the older group, a fall was significantly the most frequent injury mechanism (OR: 14.5; 95%CI: 9.9–21.3), responsible for 89.5% of the cases, while hospitalization (OR: 0.36; 95%CI: 0.23–0.56) was less characteristic. Most of the fractures occurred in the zygomatic bone, in the zygomaticomaxillary complex, or in the anterior wall of the maxilla. Associated injuries in the elderly group included mostly lower limb injuries—particularly pertrochanteric femoral fractures in females—and upper limb injuries, with a slight male dominance. Conclusions: Low-energy falls are the primary cause of midfacial fractures in elderly patients, particularly in women. Tailored prevention and management strategies are essential for improving the outcomes in this growing demographic group. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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11 pages, 261 KB  
Review
Minimally Invasive Surgical Strategies for the Treatment of Atrial Fibrillation: An Evolving Role in Contemporary Cardiac Surgery
by Luciana Benvegnù, Giorgia Cibin, Fabiola Perrone, Vincenzo Tarzia, Augusto D’Onofrio, Giovanni Battista Luciani, Gino Gerosa and Francesco Onorati
J. Cardiovasc. Dev. Dis. 2025, 12(8), 289; https://doi.org/10.3390/jcdd12080289 - 29 Jul 2025
Viewed by 964
Abstract
Atrial fibrillation remains the most frequent sustained arrhythmia, particularly in the elderly population, and is associated with increased risks of stroke, heart failure, and reduced quality of life. While catheter ablation is widely used for rhythm control, its efficacy is limited in persistent [...] Read more.
Atrial fibrillation remains the most frequent sustained arrhythmia, particularly in the elderly population, and is associated with increased risks of stroke, heart failure, and reduced quality of life. While catheter ablation is widely used for rhythm control, its efficacy is limited in persistent and long-standing atrial fibrillation. Over the past two decades, minimally invasive surgical strategies have emerged as effective alternatives, aiming to replicate the success of the Cox-Maze procedure while reducing surgical trauma. This overview critically summarizes the current minimally invasive techniques available for atrial fibrillation treatment, including mini-thoracotomy ablation, thoracoscopic ablation, and hybrid procedures such as the convergent approach. These methods offer the potential for durable sinus rhythm restoration by enabling direct visualization, transmural lesion creation, and left atrial appendage exclusion, with lower perioperative morbidity compared to traditional open surgery. The choice of energy source plays a key role in lesion efficacy and safety. Particular attention is given to the technical steps of each procedure, patient selection criteria, and the role of left atrial appendage closure in stroke prevention. Hybrid strategies, which combine epicardial surgical ablation with endocardial catheter-based procedures, have shown encouraging outcomes in patients with refractory or long-standing atrial fibrillation. Despite the steep learning curve, minimally invasive techniques provide significant benefits in terms of recovery time, reduced hospital stay, and fewer complications. As evidence continues to evolve, these approaches represent a key advancement in the surgical management of atrial fibrillation, deserving integration into contemporary treatment algorithms and multidisciplinary heart team planning. Full article
(This article belongs to the Special Issue Hybrid Ablation of the Atrial Fibrillation)
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23 pages, 4725 KB  
Tutorial
Fragility Fractures of the Pelvis—Current Understanding and Open Questions
by Amber Gordon, Michela Saracco, Peter V. Giannoudis and Nikolaos K. Kanakaris
J. Clin. Med. 2025, 14(14), 5122; https://doi.org/10.3390/jcm14145122 - 18 Jul 2025
Viewed by 3379
Abstract
Fragility fractures of the pelvis (FFPs) are common in elderly patients, particularly those with osteoporosis. FFPs can be associated with high mortality, morbidity, and functional decline. Known risk factors include being over 80 years old and delays in surgical intervention when this is [...] Read more.
Fragility fractures of the pelvis (FFPs) are common in elderly patients, particularly those with osteoporosis. FFPs can be associated with high mortality, morbidity, and functional decline. Known risk factors include being over 80 years old and delays in surgical intervention when this is required. While the role of surgery in FFPs remains less defined than in proximal femoral fractures in the elderly, studies indicate that surgical fixation offers improved survival and functional outcomes. Similarly, the choice of fixation method, whether posterior or anterior, and their combinations, vary between clinicians. It depends on the fracture type and patient-specific factors, such as bone quality and comorbidities, as well as the surgeon’s experience and the availability of resources. Additionally, orthobiologic adjuncts such as cement augmentation and sacroplasty can enhance the stability of an osteoporotic fracture during surgical intervention. Furthermore, medical treatments for osteoporosis, especially the use of teriparatide, have demonstrated beneficial effects in reducing fractures and promoting healing of the FFPs. Return to pre-injury activities is often limited, with independence rates remaining low at mid-term follow-up. Factors that influence clinical outcomes include fracture type, with Type III and IV fractures generally leading to poorer outcomes, and patient age, functional reserve, and comorbidities. The present tutorial aims to summarise the relevant evidence on all aspects of FFPs, inform an updated management strategy, and provide a template of the reconstruction ladder referring to the most available surgical techniques and treatment methods. Further research, based on large-scale studies, is needed to address the open questions described in this manuscript and refine surgical techniques, as well as determine optimal treatment pathways for this vulnerable patient population. Full article
(This article belongs to the Special Issue The “Orthogeriatric Fracture Syndrome”—Issues and Perspectives)
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12 pages, 486 KB  
Article
Five-Year Retrospective Analysis of Traumatic and Non-Traumatic Pneumothorax in 2797 Patients
by Ayhan Tabur and Alper Tabur
Healthcare 2025, 13(14), 1660; https://doi.org/10.3390/healthcare13141660 - 10 Jul 2025
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Abstract
Objectives: Pneumothorax is a critical condition frequently encountered in emergency departments (EDs), with spontaneous pneumothorax (SP) and traumatic pneumothorax (TP) presenting distinct clinical challenges. This study aimed to evaluate the epidemiological characteristics, clinical outcomes, and treatment strategies for SP and TP across different [...] Read more.
Objectives: Pneumothorax is a critical condition frequently encountered in emergency departments (EDs), with spontaneous pneumothorax (SP) and traumatic pneumothorax (TP) presenting distinct clinical challenges. This study aimed to evaluate the epidemiological characteristics, clinical outcomes, and treatment strategies for SP and TP across different age groups and provide insights for optimizing emergency management protocols. Methods: This retrospective cohort study analyzed 2797 cases of pneumothorax over five years (2018–2023) at a tertiary care center. Patients were stratified by age (18–39, 40–64, and >65 years) and pneumothorax type (SP vs. TP). Data on demographics, clinical presentation, treatment, hospital stay, recurrence, and complications were extracted from medical records. Comparative statistical analyses were also conducted. Results: The mean age of patients with SP was 32.5 ± 14.7 years, whereas patients with TP were older (37.8 ± 16.2 years, p < 0.001). Male predominance was observed in both groups: 2085 (87.0%) in the SP group and 368 (92.0%) in the TP group (p = 0.01). The right lung was more frequently affected in the SP (64.2%) and TP (56.0%) groups (p < 0.001). Age-related differences were evident in both groups of patients. In the SP group, younger patients (18–39 years) represented the majority of cases, whereas older patients (≥65 years) were more likely to present with SSP and required more invasive management (p < 0.01). In the TP group, younger patients often had pneumothorax due to high-energy trauma, whereas older individuals developed pneumothorax due to falls or iatrogenic causes (p < 0.01). SP predominantly affected younger patients, with a history of smoking and male predominance associated with younger age (p < 0.01). TP is more frequent in older patients, often because of falls or iatrogenic injuries. Management strategies varied by age group; younger patients were often managed conservatively, whereas older patients underwent more invasive procedures (p < 0.01). Surgical intervention was more common in younger patients in the TP group, whereas conservative management was more frequent in elderly patients (p < 0.01). The clinical outcomes differed significantly, with older patients having longer hospital stays and higher rates of persistent air leaks (p < 0.01). Recurrence was more common in younger patients with SP, whereas TP recurrence rates were lower across all age groups (p < 0.01). No significant differences were observed in re-expansion pulmonary edema, empyema, or mortality rates between the age groups, suggesting that age alone was not an independent predictor of these complications when adjusted for pneumothorax severity and management strategy (p = 0.22). Conclusions: Age, pneumothorax subtype, and underlying pulmonary comorbidities were identified as key predictors of clinical outcomes. Advanced age, secondary spontaneous pneumothorax, and COPD were independently associated with recurrence, prolonged hospitalization, and in-hospital mortality, respectively. These findings highlight the need for risk-adapted management strategies to improve triaging and treatment decisions for spontaneous and traumatic pneumothorax. Full article
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