Search Results (4,510)

Visible Light Positioning (VLP) has emerged as a pivotal technology for industrial Internet of Things (IoT) and smart logistics, offering high accuracy, immunity to electromagnetic interference, and cost-effectiveness. However, fluctuations in signal gain caused by target motion significantly degrade the positioning accuracy of current VLP systems. Conventional approaches face intrinsic limitations: propagation-model-based techniques rely on static assumptions, fingerprint-based approaches are highly sensitive to dynamic parameter variations, and although CNN/LSTM-based models achieve high accuracy under static conditions, their inability to capture long-term temporal dependencies leads to unstable performance in dynamic scenarios. To overcome these challenges, we propose a novel dynamic VLP algorithm that incorporates a Spatio-Temporal Feature Information Network (STFI-Net) for joint localization and orientation estimation of moving targets. The proposed method integrates a two-layer convolutional block for spatial feature extraction and employs modern Temporal Convolutional Networks (TCNs) with dilated convolutions to capture multi-scale temporal dependencies in dynamic environments. Experimental results demonstrate that the STFI-Net-based system enhances positioning accuracy by over 26% compared to state-of-the-art methods while maintaining robustness in the face of complex motion patterns and environmental variations. This work introduces a novel framework for deep learning-enabled dynamic VLP systems, providing more efficient, accurate, and scalable solutions for indoor positioning. Full article

:With the proliferation of image-capturing and display-enabled IoT devices, ensuring the authenticity and integrity of visual data has become increasingly critical, especially in light of emerging cybersecurity threats and powerful generative AI tools. One of the major challenges in such sensor-based systems is the ability to protect privacy while maintaining data usability. Reversible data hiding has attracted growing attention due to its reversibility and ease of implementation, making it a viable solution for secure image communication in IoT environments. In this paper, we propose reversible data hiding techniques tailored to the content characteristics of images. Our approach leverages subsampling and quadtree partitioning, combined with multi-stage prediction schemes, to generate a predicted image aligned with the original. Secret information is embedded by analyzing the difference histogram between the original and predicted images, and enhanced through multi-round rotation techniques and a multi-level embedding strategy to boost capacity. By employing both subsampling and quadtree decomposition, the embedding strategy dynamically adapts to the inherent characteristics of the input image. Furthermore, we investigate the trade-off between embedding capacity and marked image quality. Experimental results demonstrate improved embedding performance, high visual fidelity, and low implementation complexity, highlighting the method’s suitability for resource-constrained IoT applications. Full article

Cognition is often modeled in terms of abstract reasoning and neural computation, yet a growing body of theoretical and experimental work suggests that the roots of cognition lie in fundamental embodied regulatory processes. This article presents a theory of cognition grounded in sensing, feeling, and affect—capacities that precede neural systems and are observable in even the simplest living organisms. Based on the info-computational framework, this entry outlines how cognition and proto-subjectivity co-emerge in biological systems. Embodied appraisal—the system’s ability to evaluate internal and external conditions in terms of valence (positive/negative; good/bad)—and the capacity to regulate accordingly are described as mutually constitutive processes observable at the cellular level. This concept reframes cognition not as abstract symbolic reasoning but as value-sensitive, embodied information dynamics resulting from self-regulating engagement with the environment that spans scales from unicellular organisms to complex animals. In this context, information is physically instantiated, and computation is the dynamic, self-modifying process by which organisms regulate and organize themselves. Cognition thus emerges from the dynamic coupling of sensing, internal evaluation, and adaptive morphological (material shape-based) activity. Grounded in findings from developmental biology, bioelectric signaling, morphological computation, and basal cognition, this account situates intelligence as an affect-driven regulatory capacity intrinsic to biological life. While focused on biological systems, this framework also offers conceptual insights for developing more adaptive and embodied forms of artificial intelligence. Future experiments with minimal living systems or synthetic agents may help operationalize and test the proposed mechanisms of proto-subjectivity and affect regulation. Full article

Background: Interoperability is fundamental for advancing digital health and digital therapeutics, particularly with the integration of technologies such as artificial intelligence (AI), blockchain, and federated learning. Low- and middle-income countries (LMICs), where digital infrastructure remains fragmented, face specific challenges in implementing standardized and scalable systems. Methods: This scoping review was conducted using the Arksey and O’Malley framework, refined by Levac et al., and the Joanna Briggs Institute guidelines. Five databases (PubMed, Scopus, IEEE Xplore, ACM Digital Library, and Google Scholar) were searched for peer-reviewed English language studies published between 2015 and 2025. We identified 255 potentially eligible articles and selected a 10% random sample (n = 26) using Stata 18 by StataCorp LLC, College Station, TX, USA, for in-depth data charting and thematic synthesis. Results: The selected studies spanned over 15 countries and addressed priority technologies, including mobile health (mHealth), the use of Health Level Seven (HL7)’s Fast Healthcare Interoperability Resources (FHIR) for data exchange, and blockchain. Interoperability enablers include standards (e.g., HL7 FHIR), data governance frameworks, and policy interventions. Low- and Middle-Income Countries (LMICs) face common issues related to digital capacity shortages, legacy systems, and governance fragmentation. Five thematic areas were identified: (1) policy and governance; (2) standards-based integration; (3) infrastructure and platforms; (4) emerging technologies; and (5) LMIC implementation issues. Conclusions: Emerging digital health technologies increasingly rely on interoperability standards to scale their operation. Although global standards such as FHIR and the Trusted Exchange Framework and Common Agreement (TEFCA) are gaining momentum, LMICs require dedicated governance, infrastructure, and capacity investments to make equitable use feasible. Future initiatives can benefit from using science- and equity-informed frameworks. Full article

Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain, fatigue, non-restorative sleep, and cognitive impairment. Its pathogenesis reflects a complex interplay between central and peripheral mechanisms, including altered pain modulation, neuroinflammation, mitochondrial dysfunction, autonomic imbalance, and genetic and epigenetic factors. Evidence from neuroimaging, omics studies, and neurophysiology supports this multifactorial model. Epidemiological updates confirm a global prevalence of 2–8%, with a strong female predominance and a significant impact on quality of life and healthcare costs. Diagnostic criteria have evolved from the 1990 American College of Rheumatology tender points to the 2010/2011 revisions and the 2016 update, improving case ascertainment but still lacking objective biomarkers. Recent omics and systems biology approaches have revealed transcriptional, proteomic, and metabolic signatures that may enable molecularly informed stratification. Therapeutic management remains multidisciplinary, combining pharmacological interventions (e.g., duloxetine, pregabalin, milnacipran) with non-pharmacological strategies such as graded aerobic exercise and cognitive behavioral therapy. Emerging approaches include drug repurposing to target neuroinflammation, mitochondrial dysfunction, and nociceptive pathways. Despite promising advances, progress is limited by small sample sizes, heterogeneous cohorts, and lack of standardization across studies. Future priorities include large-scale validation of biomarkers, integration of multi-omics with clinical phenotyping, and the design of precision-guided trials. By synthesizing mechanistic insights with clinical evidence, this review provides an updated framework for the diagnosis and management of fibromyalgia, highlighting pathways toward biomarker-guided, personalized medicine. Full article

Non-perturbative approaches to linear and nonlinear responses (NLR) of atoms, molecules, and molecular aggregates are reviewed in relation to low and high harmonic generations (HG) by laser fields. These response properties are effective for the generation of entangled light pairs for quantum information processing by spontaneous parametric downconversion (SPDC) and stimulated four-wave mixing (SFWM). Quasi-energy derivative (QED) methods, such as QED Møller–Plesset (MP) perturbation, are reviewed as time-dependent variational methods (TDVP), providing analytical expressions of time-dependent linear and nonlinear responses of open-shell atoms, molecules, and molecular aggregates. Numerical Liouville methods for the low HG (LHG) and high HG (HHG) regimes are reviewed to elucidate the NLR of molecules in both LHG and HHG regimes. Three-step models for the generation of HHG in the latter regime are reviewed in relation to developments of attosecond science and spectroscopy. Orbital tomography is also reviewed in relation to the theoretical and experimental studies of the amplitudes and phases of wave functions of open-shell atoms and molecules, such as molecular oxygen, providing the Dyson orbital explanation. Interactions between quantum lights and molecules are theoretically examined in relation to derivations of several distribution functions for quantum information processing, quantum dynamics of molecular aggregates, and future developments of quantum molecular devices such as measurement-based quantum computation (MBQP). Quantum dynamics for energy transfer in dendrimer and related light-harvesting antenna systems are reviewed to examine the classical and quantum dynamics behaviors of photosynthesis. It is shown that quantum coherence plays an important role in the well-organized arrays of chromophores. Finally, applications of quantum optics to molecular quantum information and quantum biology are examined in relation to emerging interdisciplinary frontiers. Full article

The evolution of decentralized clinical trials, driven by advanced digital technologies, is transforming traditional clinical research. It introduces innovative methods for informed consent, remote patient monitoring, and data analysis, enhancing study efficiency, validity, and participation while reducing patient burden. Some clinical procedures can be conducted remotely, increasing trial accessibility and reducing population selection biases, particularly for cardiovascular patients. However, this also presents complex regulatory and ethical challenges. The article explores how digital platforms and emerging technologies like block chain, AI, and advanced cryptography can promote traceability, security, and transparency throughout the trial process, ensuring participant identification and documentation of each procedural step. Clear, legally compliant informed consent, often managed through electronic systems, both for research participation and data management in line with GDPR, is essential. Ethical considerations include ensuring participants understand trial information, with adaptations such as simplified language, visual aids, and multilingual support. The transnational nature of decentralized trials highlights the need for coordinated regulatory standards to overcome jurisdictional barriers and reinforce accountability. This framework promotes trust, shared responsibility, and the protection of participants rights while upholding high ethical standards in scientific research. Full article

Background: Immunisation remains one of the most effective and cost-efficient public health interventions for preventing infectious diseases in children. Despite global progress, Sub-Saharan Africa (SSA) continues to face challenges in achieving equitable immunisation coverage. Gender-related disparities, rooted in sociocultural and structural inequalities, significantly influence the prevalence of zero-dose and under-immunised children in the region. This review critically examines the gender-associated barriers to routine childhood immunisation in SSA to inform more inclusive and equitable health interventions. Methods: A critical literature review was conducted generally following some steps of the PRISMA-P and CRD guidelines. Using the Population–Concept–Context (PCC) framework, studies were selected that examined gender-related barriers to routine immunisation for children under five in Sub-Saharan Africa. Comprehensive searches were performed across PubMed, Google Scholar, and relevant organisational websites, targeting articles published between 2015 and 2025. A total of 3683 articles were retrieved, with 24 studies ultimately meeting the inclusion criteria. Thematic analysis was used to synthesise the findings. Results: Four major themes emerged: (1) women’s empowerment and autonomy, including limited decision-making power, financial control, and the impact of gender-based violence; (2) male involvement and prevailing gender norms, where patriarchal structures and low male engagement negatively influenced vaccine uptake; (3) socioeconomic and structural barriers, such as poverty, geographic inaccessibility, maternal workload, and service availability; and (4) education, awareness, and health system responsiveness. Conclusions: Gender dynamics have a significant impact on childhood immunisation outcomes in Sub-Saharan Africa. Future policies must integrate these insights to improve immunisation equity and reduce preventable child morbidity and mortality across the region. Full article

Integrated sensing and communication (ISAC) has emerged as a transformative technology for intelligent transportation systems. Index modulation (IM), recognized for its high robustness and energy efficiency (EE), has been successfully incorporated into ISAC systems. However, most existing IM-based ISAC schemes overlook the spatial multiplexing potential of millimeter-wave channels and remain confined to single-hop vehicle-to-vehicle (V2V) setups, failing to address the challenges of energy consumption and noise accumulation in real-world multi-hop V2V networks with complex road topologies. To bridge this gap, we propose a spatial scattering modulation-based ISAC (ISAC-SSM) scheme and introduce it to multi-hop V2V networks. The proposed scheme leverages the sensed positioning information to select maximum signal-to-noise ratio relay vehicles and employs a detect-amplify-and-forward (DAF) protocol to mitigate noise propagation, while utilizing sensed angle data for Doppler compensation to enhance communication reliability. At each hop, the transmitter modulates index bits on the angular-domain spatial directions of scattering clusters, achieving higher EE. We initially derive a closed-form bit error rate expression and Chernoff upper bound for the proposed DAF ISAC-SSM under multi-hop V2V networks. Both theoretical analyses and Monte Carlo simulations have been made and demonstrate the superiority of DAF ISAC-SSM over existing alternatives in terms of EE and error performance. Specifically, in a two-hop network with 12 scattering clusters, compared with DAF ISAC-conventional spatial multiplexing, DAF ISAC-maximum beamforming, and DAF ISAC-random beamforming, the proposed DAF ISAC-SSM scheme can achieve a coding gain of 1.5 dB, 2 dB, and 4 dB, respectively. Moreover, it shows robust performance with less than a 1.5 dB error degradation under 0.018 Doppler shifts, thereby verifying its superiority in practical vehicular environments. Full article

Objective: This study investigates how artificial intelligence (AI) research relates to firm value, focusing on dominant thematic trends, theoretical foundations, and global collaboration patterns. Methods: A PRISMA-guided systematic review was conducted on 219 peer-reviewed articles published between 2013 and May 2025 in the Web of Science Social Sciences Citation Index. Bibliometric techniques, including co-word, co-citation, and collaboration network analyses, were performed using the bibliometrix (version 4.2.3) in R (version 4.4.2) package to map key concepts, intellectual structures, and international research partnerships. Results: The literature is primarily grounded in strategic management theories such as the resource-based view (RBV) and dynamic capabilities. Emerging research streams emphasize digital transformation, big data analytics, and decision support systems. Frequently co-occurring terms include “firm performance,” “artificial intelligence,” “dynamic capabilities,” “information technology,” and “decision-making.” Collaboration mapping highlights the United States, United Kingdom, and China as leading hubs, with increasing contributions from emerging economies such as India, Malaysia, and Saudi Arabia. The alignment between co-word and co-citation structures reflects a shift from foundational theory to applied AI capabilities in firm-value creation. Implications: By integrating a systematic review with advanced bibliometric and science-mapping methods, this work establishes a structured foundation for theory development, empirical testing, and policy formulation in AI-driven business landscapes. Full article

Fractional-order chaotic systems have emerged as powerful tools in secure communications and multimedia protection owing to their memory-dependent dynamics, large key spaces, and high sensitivity to initial conditions. However, most existing fractional-order image encryption schemes rely on fixed-order chaos and conventional solvers, which limit their complexity and reduce unpredictability, while also neglecting the potential of variable fractional-order (VFO) dynamics. Although similar phenomena have been reported in some fractional-order systems, the coexistence of hidden attractors and stable equilibria has not been extensively investigated within VFO frameworks. To address these gaps, this paper introduces a novel discrete variable fractional-order dark matter–dark energy (VFODM-DE) chaotic system. The system is discretized using the piecewise constant argument discretization (PWCAD) method, enabling chaos to emerge at significantly lower fractional orders than previously reported. A comprehensive dynamic analysis is performed, revealing rich behaviors such as multistability, symmetry properties, and hidden attractors coexisting with stable equilibria. Leveraging these enhanced chaotic features, a pseudorandom number generator (PRNG) is constructed from the VFODM-DE system and applied to grayscale image encryption through permutation–diffusion operations. Security evaluations demonstrate that the proposed scheme offers a substantially large key space (approximately $2^{249}$) and exceptional key sensitivity. The scheme generates ciphertexts with nearly uniform histograms, extremely low pixel correlation coefficients (less than 0.04), and high information entropy values (close to 8 bits). Moreover, it demonstrates strong resilience against differential attacks, achieving average NPCR and UACI values of about 99.6% and 33.46%, respectively, while maintaining robustness under data loss conditions. In addition, the proposed framework achieves a high encryption throughput, reaching an average speed of 647.56 Mbps. These results confirm that combining VFO dynamics with PWCAD enriches the chaotic complexity and provides a powerful framework for developing efficient and robust chaos-based image encryption algorithms. Full article

The actomyosin complex—nature’s dynamic engine composed of actin filaments and myosin motors—is emerging as a versatile tool for bio-integrated nanotechnology. This review explores the growing potential of actomyosin-powered systems in biosensing and actuation applications, highlighting their compatibility with physiological conditions, responsiveness to biochemical and physical cues and modular adaptability. We begin with a comparative overview of natural and synthetic nanomachines, positioning actomyosin as a uniquely scalable and biocompatible platform. We then discuss experimental advances in controlling actomyosin activity through ATP, calcium, heat, light and electric fields, as well as their integration into in vitro motility assays, soft robotics and neural interface systems. Emphasis is placed on longstanding efforts to harness actomyosin as a biosensing element—capable of converting chemical or environmental signals into measurable mechanical or electrical outputs that can be used to provide valuable clinical and basic science information such as functional consequences of disease-associated genetic variants in cardiovascular genes. We also highlight engineering challenges such as stability, spatial control and upscaling, and examine speculative future directions, including emotion-responsive nanodevices. By bridging cell biology and bioengineering, actomyosin-based systems offer promising avenues for real-time sensing, diagnostics and therapeutic feedback in next-generation biosensors. Full article

In the face of ever-evolving cyber threats, modern intrusion detection systems (IDS) must achieve long-term adaptability without sacrificing performance on previously encountered attacks. Traditional IDS approaches often rely on static training assumptions, making them prone to forgetting old patterns, underperforming in label-scarce conditions, and struggling with imbalanced class distributions as new attacks emerge. To overcome these limitations, we present a continual learning framework tailored for adaptive intrusion detection. Unlike prior methods, our approach is designed to operate under real-world network conditions characterized by high-dimensional, sparse traffic data and task-agnostic learning sequences. The framework combines three core components: a clustering-based memory strategy that selectively retains informative historical samples using DP-Means; multi-level knowledge distillation that aligns current and previous model states at output and intermediate feature levels; and a meta-learning-driven class reweighting mechanism that dynamically adjusts to shifting attack distributions. Empirical evaluations on benchmark intrusion detection datasets demonstrate the framework’s ability to maintain high detection accuracy while effectively mitigating forgetting. Notably, it delivers reliable performance in continually changing environments where the availability of labeled data is limited, making it well-suited for real-world cybersecurity systems. Full article

Automatic speech recognition (ASR) has advanced rapidly, evolving from early template-matching systems to modern deep learning frameworks. This review systematically traces ASR’s technological evolution across four phases: the template-based era, statistical modeling approaches, the deep learning revolution, and the emergence of large-scale models under diverse learning paradigms. We analyze core technologies such as hidden Markov models (HMMs), Gaussian mixture models (GMMs), recurrent neural networks (RNNs), and recent architectures including Transformer-based models and Wav2Vec 2.0. Beyond algorithmic development, we examine how ASR integrates into intelligent information systems, analyzing real-world applications in healthcare, education, smart homes, enterprise systems, and automotive domains with attention to deployment considerations and system design. We also address persistent challenges—noise robustness, low-resource adaptation, and deployment efficiency—while exploring emerging solutions such as multimodal fusion, privacy-preserving modeling, and lightweight architectures. Finally, we outline future research directions to guide the development of robust, scalable, and intelligent ASR systems for complex, evolving environments. Full article

Emergency medical services confront significant challenges in delivering timely patient assessments within geographically isolated or disaster-impacted regions. While drones (unmanned aircraft systems, UAS) show transformative potential in healthcare, standardized protocols for drone-assisted patient evaluations remain underdeveloped. This study introduces the ABCD-IN-BARS protocol, a 9-step telemedicine checklist integrating patient-assisted maneuvers and drone technology to systematize remote emergency assessments. A wait-list randomized controlled trial with 68 first-aid-trained volunteers evaluated the protocol’s feasibility. Participants underwent web-based modules and in-person simulations and were randomized into immediate training or waitlist control groups. The ABCD-IN-BARS protocol was developed via a content validity approach, incorporating expert-rated items from the telemedicine literature. Outcomes included time-to-assessment, provider confidence (Modified Cooper–Harper Scale), measured at baseline, post-training, and 3-month follow-up. Ethical approval and informed consent were obtained. Most of the participants can complete the assessment with a cue card within 4 min. A mixed-design repeated measures ANOVA assessed the effects of Time (baseline, post-test, 3-month follow-up within subject) on assessment durations. Assessment times improved significantly over three time points (p = 0.008), improving with standardized protocols, while patterns were similar across groups (p = 0.101), reflecting skill retention at 3 months and not affected by injury or not. Protocol adherence in simulated injury identification increased from 63.3% pre-training to 100% post-training. Provider confidence remained high (MCH scores: 2.4–2.7/10), and Technology Acceptance Model (TAM) ratings emphasized strong Perceived Usefulness (PU2: M = 4.48) despite moderate ease-of-use challenges (EU2: M = 4.03). Qualitative feedback highlighted workflow benefits but noted challenges in drone maneuvering. The ABCD-IN-BARS protocol effectively standardizes drone-assisted emergency assessments, demonstrating retained proficiency and high usability. While sensory limitations persist, its modular design and alignment with ABCDE principles offer a scalable solution for prehospital care in underserved regions. Further multicenter validation is needed to generalize findings. Full article