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29 pages, 5291 KB  
Article
Optimal Sliding Mode Fault-Tolerant Control for Multiple Robotic Manipulators via Critic-Only Dynamic Programming
by Xiaoguang Zhang, Zhou Yang, Haitao Liu and Xin Huang
Sensors 2025, 25(17), 5410; https://doi.org/10.3390/s25175410 (registering DOI) - 2 Sep 2025
Abstract
This paper proposes optimal sliding mode fault-tolerant control for multiple robotic manipulators in the presence of external disturbances and actuator faults. First, a quantitative prescribed performance control (QPPC) strategy is constructed, which relaxes the constraints on initial conditions while strictly restricting the trajectory [...] Read more.
This paper proposes optimal sliding mode fault-tolerant control for multiple robotic manipulators in the presence of external disturbances and actuator faults. First, a quantitative prescribed performance control (QPPC) strategy is constructed, which relaxes the constraints on initial conditions while strictly restricting the trajectory within a preset range. Second, based on QPPC, adaptive gain integral terminal sliding mode control (AGITSMC) is designed to enhance the anti-interference capability of robotic manipulators in complex environments. Third, a critic-only neural network optimal dynamic programming (CNNODP) strategy is proposed to learn the optimal value function and control policy. This strategy fits nonlinearities solely through critic networks and uses residuals and historical samples from reinforcement learning to drive neural network updates, achieving optimal control with lower computational costs. Finally, the boundedness and stability of the system are proven via the Lyapunov stability theorem. Compared with existing sliding mode control methods, the proposed method reduces the maximum position error by up to 25% and the peak control torque by up to 16.5%, effectively improving the dynamic response accuracy and energy efficiency of the system. Full article
(This article belongs to the Section Sensors and Robotics)
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39 pages, 3473 KB  
Article
Mathematical Modeling and Design of a Cooling Crystallizer Incorporating Experimental Data for Crystallization Kinetics
by Panagiotis A. Michailidis and Argyris Panagopoulos
ChemEngineering 2025, 9(5), 97; https://doi.org/10.3390/chemengineering9050097 (registering DOI) - 2 Sep 2025
Abstract
Crystallization is one of the approximately twenty unit operations and is considered to be among the most important due to the large number of chemical compounds it produces, as well as due to the enormous quantities of these substances being manufactured around the [...] Read more.
Crystallization is one of the approximately twenty unit operations and is considered to be among the most important due to the large number of chemical compounds it produces, as well as due to the enormous quantities of these substances being manufactured around the world. This article aims to present a mathematical model for the shortcut design of a cooling crystallization unit consisting of the crystallizer and auxiliary equipment, such as an evaporator with its preheater and condenser, a heat pump that acts as the cooling system of the crystallizer, and a crystallizer pressure regulator modeled as an expansion valve. The model estimates an extensive series of variables, including mass and volume flow rates of the streams, heat duties of each piece of equipment, sizing variables such as heat transfer areas of heat exchangers and volumes of the vessels, and product flow rates for each specific feed. It embraces equations for the calculation of a series of stream properties, such as density, specific heat capacity, and latent heat of vaporization. For the sizing of the crystallizer, which is the main equipment of the unit, both flow rates and crystallization kinetics are taken into account. The latter is estimated by experimental data taken in a laboratory crystallizer and includes the crystal’s growth rate as a function of residence time. Full article
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26 pages, 7753 KB  
Article
Reducing Carbon Footprint in Petrochemical Plants by Analysis of Entropy Generation for Flow in Sudden Pipe Contraction
by Rached Ben-Mansour
Eng 2025, 6(9), 216; https://doi.org/10.3390/eng6090216 (registering DOI) - 2 Sep 2025
Abstract
A very important method of reducing carbon emissions is to make sure industrial plants are operated at optimal energy efficiency. The oil and petrochemical industries spend large amounts of energy in the transportation of petroleum and its various products that have high viscosities. [...] Read more.
A very important method of reducing carbon emissions is to make sure industrial plants are operated at optimal energy efficiency. The oil and petrochemical industries spend large amounts of energy in the transportation of petroleum and its various products that have high viscosities. A critical component in these plants is abrupt pipe contraction. Large amounts of energy are lost in pipe contractions. In this paper we investigate the energy losses in pipe contraction using the local entropy generation method after solving the detailed flow field around an abrupt pipe contraction. We have applied the method at various Reynolds numbers covering laminar and turbulent flow regimes. Furthermore, we have used an integral entropy analysis and found excellent agreement between the differential and integral entropy methods when the computational grid is well refined. The differential analysis was able to predict the local entropy generation and find where the large losses are located and therefore be able to minimize these losses effectively. Based on the detailed entropy generation field, it is recommended to use rounded contraction in order to reduce the losses. By introducing rounded contractions in laminar flow, the losses have been reduced by 22%. In the case of the turbulent flow regime, the losses were reduced by 96% by introducing a rounding radius to diameter ratio r/D2 of 10%. The turbulent flow results for the case of pipe entrance, which is a special case of abrupt contraction (D2/D1 goes to zero) agree very well with the present results. This work addresses a large range of D2/D1 for laminar and turbulent flows. It is recommended that companies involved in designing petrochemical plants and installations take these findings into consideration to reduce carbon emissions. These recommendations also extend to the design of equipment and piping systems for the food industry and micro-device flows. Full article
(This article belongs to the Special Issue Advances in Decarbonisation Technologies for Industrial Processes)
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21 pages, 2924 KB  
Article
Feasibility Study on Using Calcium Lignosulfonate-Modified Loess for Landfill Leachate Filtration and Seepage Control
by Jinjun Guo, Wenle Hu and Shixu Zhang
ChemEngineering 2025, 9(5), 96; https://doi.org/10.3390/chemengineering9050096 (registering DOI) - 2 Sep 2025
Abstract
Prolonged exposure to landfill leachate can weaken the impermeability of liner systems, leading to leachate leakage and the contamination of surrounding soil and water. To improve loess impermeability to enable its use as a liner material, this study uses synthetic landfill leachate to [...] Read more.
Prolonged exposure to landfill leachate can weaken the impermeability of liner systems, leading to leachate leakage and the contamination of surrounding soil and water. To improve loess impermeability to enable its use as a liner material, this study uses synthetic landfill leachate to investigate its effects on loess permeability via a series of laboratory tests. This study focused on the influence of varying dosages of calcium lignosulfonate (CLS) on loess permeability, along with its capacity to adsorb and immobilize heavy metal ions. Microscale characterization techniques, including Zeta potential analysis, X-ray fluorescence spectroscopy (XRF), and scanning electron microscopy (SEM), were employed to investigate the impermeability mechanisms of CLS-modified loess and its adsorption behavior toward heavy metals. The results indicate that the permeability coefficient of loess decreases significantly with increasing compaction, while higher leachate concentrations lead to a notable increase in permeability. At a compaction degree of 0.90, the permeability coefficient was reduced to 8 × 10−8 cm/s. In contrast, under conditions of maximum leachate concentration, the permeability coefficient rose markedly to 1.5 × 10−4 cm/s. Additionally, increasing the dosage of the compacted loess stabilizer (CLS) effectively reduced the permeability coefficient of the modified loess to 7.1 × 10−5 cm/s, indicating improved impermeability and enhanced resistance to contaminant migration. With the prolonged infiltration time of landfill leachate, the removal efficiency of Pb2+ gradually decreases and stabilizes, while the Pb2+ removal efficiency of the modified loess increased by approximately 40%. CLS-modified loess, through multiple mechanisms, reduces the fluid flow pathways and enhances its adsorption capacity for Pb2+, thereby improving the soil’s protection against heavy metal contamination. While these results demonstrate the potential of CLS-modified loess as a sustainable landfill liner material, the findings are based on controlled laboratory conditions with Pb2+ as the sole target contaminant. Future work should evaluate long-term performance under field conditions, including seasonal wetting–drying and freeze–thaw cycles, and investigate multi-metal systems to validate the broader applicability of this modification technique. Full article
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31 pages, 1511 KB  
Article
Economic Evaluation During Physicochemical Characterization Process: A Cost–Benefit Analysis
by Despina A. Gkika, Nick Vordos, Athanasios C. Mitropoulos and George Z. Kyzas
ChemEngineering 2025, 9(5), 95; https://doi.org/10.3390/chemengineering9050095 (registering DOI) - 2 Sep 2025
Abstract
As academic institutions expand, the proliferation of laboratories dealing with hazardous chemicals has risen. While the physicochemical characterization equipment employed in these academic chemical laboratories is widely recognized, its usage presents a notable risk to researchers at various levels. This paper presents a [...] Read more.
As academic institutions expand, the proliferation of laboratories dealing with hazardous chemicals has risen. While the physicochemical characterization equipment employed in these academic chemical laboratories is widely recognized, its usage presents a notable risk to researchers at various levels. This paper presents a simplified approach for evaluating the effects of the implementation of prevention investments in regard to working with nanomaterials on a lab scale. The evaluation is based on modeling the benefits (avoided accident costs) and costs (safety training), as opposed to an alternative (not investing in safety training). Each scenario analyzed in the economic evaluation reflects a different level of risk. The novelty of this study lies in its objective to provide an economic assessment of the benefits and returns from safety investments—specifically training—in a chemical laboratory, using a framework that integrates qualitative insights to explore and define the context alongside quantitative data derived from a cost–benefit analysis. The Net Present Value (NPV) was evaluated. The results of the cost–benefit analysis demonstrated that the benefits exceed the cost of the investment. The findings from the sensitivity analysis highlight the significant influence of insurance benefits on safety investments in the specific case study. In this case study, the deterministic analysis yielded a Net Present Value (NPV) of €280,414.67, which aligns closely with the probabilistic results. The probabilistic NPV indicates 90% confidence that the investment will yield a positive NPV ranging from €283,053 to €337,356. The cost–benefit analysis results demonstrate that the benefits outweigh the costs, showing that with an 87% training success rate, this investment would generate benefits of approximately €6328 by preventing accidents in this study. To the best of the researchers’ knowledge, this is the first study to evaluate the influence of safety investment through an economic evaluation of laboratory accidents with small-angle X-ray scattering during the physicochemical characterization process of engineered nanomaterials. The proposed approach and framework are relevant not only to academic settings but also to industry. Full article
(This article belongs to the Special Issue New Advances in Chemical Engineering)
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23 pages, 2718 KB  
Article
Deep Learning Image-Based Classification for Post-Earthquake Damage Level Prediction Using UAVs
by Norah Alsaaran and Adel Soudani
Sensors 2025, 25(17), 5406; https://doi.org/10.3390/s25175406 (registering DOI) - 2 Sep 2025
Abstract
Unmanned Aerial Vehicles (UAVs) integrated with lightweight deep learning models represent an effective solution for image-based rapid post-earthquake damage assessment. UAVs, equipped with cameras, capture high-resolution aerial imagery of disaster-stricken areas, providing essential data for evaluating structural damage. When paired with light eight [...] Read more.
Unmanned Aerial Vehicles (UAVs) integrated with lightweight deep learning models represent an effective solution for image-based rapid post-earthquake damage assessment. UAVs, equipped with cameras, capture high-resolution aerial imagery of disaster-stricken areas, providing essential data for evaluating structural damage. When paired with light eight Convolutional Neural Network (CNN) models, these UAVs can process the captured images onboard, enabling real-time, accurate damage level predictions that might with potential interest to orient efficiently the efforts of the Search and Rescue (SAR) teams. This study investigates the use of the MobileNetV3-Small lightweight CNN model for real-time post-earthquake damage level prediction using UAV-captured imagery. The model is trained to classify three levels of post-earthquake damage, ranging from no damage to severe damage. Experimental results show that the adapted MobileNetV3-Small model achieves the lowest FLOPs, with a significant reduction of 58.8% compared to the ShuffleNetv2 model. Fine-tuning the last five layers resulted in a slight increase of approximately 0.2% in FLOPs, but significantly improved accuracy and robustness, yielding a 4.5% performance boost over the baseline. The model achieved a weighted average F-score of 0.93 on a merged dataset composed of three post-earthquake damage level datasets. It was successfully deployed and tested on a Raspberry Pi 5, demonstrating its feasibility for edge-device applications. This deployment highlighted the model’s efficiency and real-time performance in resource-constrained environments. Full article
(This article belongs to the Section Vehicular Sensing)
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16 pages, 4614 KB  
Article
Influence of Plasma Assistance on EB-PVD TBC Coating Thickness Distribution and Morphology
by Grzegorz Maciaszek, Krzysztof Cioch, Andrzej Nowotnik and Damian Nabel
Materials 2025, 18(17), 4109; https://doi.org/10.3390/ma18174109 (registering DOI) - 1 Sep 2025
Abstract
In this study, the effects of plasma assistance on the electron beam physical vapour deposition (EB-PVD) process were investigated using an industrial coater (Smart Coater ALD Vacuum Technologies GmbH) equipped with a dual hollow cathode system. This configuration enabled the generation of a [...] Read more.
In this study, the effects of plasma assistance on the electron beam physical vapour deposition (EB-PVD) process were investigated using an industrial coater (Smart Coater ALD Vacuum Technologies GmbH) equipped with a dual hollow cathode system. This configuration enabled the generation of a plasma environment during the deposition of the ceramic top coat onto a metallic substrate. The objective was to assess how plasma assistance influences the microstructure and thickness distribution of 7% wt. yttria-stabilised zirconia (YSZ) thermal barrier coatings (TBCs). Coatings were deposited with and without plasma assistance to enable a direct comparison. The thickness uniformity and columnar morphology of the 7YSZ top coats were evaluated by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The mechanical properties of the deposited coatings were verified by the scratch test method. The results demonstrate that, in the presence of plasma, columnar grains become more uniformly spaced and exhibit sharper, well-defined boundaries even at reduced substrate temperatures. XRD analysis confirmed that plasma-assisted EB-PVD processes allow for maintaining the desired tetragonal phase of YSZ without inducing secondary phases or unwanted texture changes. These findings indicate that plasma-assisted EB-PVD can achieve desirable coating characteristics (uniform thickness and optimised columnar structure) more efficiently, offering potential advantages for high-temperature applications in aerospace and power-generation industries. Continued development of the EB-PVD process with the assistance of plasma generation could further improve deposition rates and TBC performance, underscoring the promising future of HC-assisted EB-PVD technology. Full article
(This article belongs to the Special Issue Advancements in Thin Film Deposition Technologies)
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23 pages, 2012 KB  
Article
Preliminary Design Guidelines for Evaluating Immersive Industrial Safety Training
by André Cordeiro, Regina Leite, Lucas Almeida, Cintia Neves, Tiago Silva, Alexandre Siqueira, Marcio Catapan and Ingrid Winkler
Informatics 2025, 12(3), 88; https://doi.org/10.3390/informatics12030088 (registering DOI) - 1 Sep 2025
Abstract
This study presents preliminary design guidelines to support the evaluation of industrial safety training using immersive technologies, with a focus on high-risk work environments such as working at height. Although virtual reality has been widely adopted for training, few studies have explored its [...] Read more.
This study presents preliminary design guidelines to support the evaluation of industrial safety training using immersive technologies, with a focus on high-risk work environments such as working at height. Although virtual reality has been widely adopted for training, few studies have explored its use for behavior-level evaluation, corresponding to Level 3 of the Kirkpatrick Model. Addressing this gap, the study adopts the Design Science Research methodology, combining a systematic literature review with expert focus group analysis to develop a conceptual framework for training evaluation. The results identify key elements necessary for immersive training evaluations, including scenario configuration, ethical procedures, recruitment, equipment selection, experimental design, and implementation strategies. The resulting guidelines are organized into six categories: scenario configuration, ethical procedures, recruitment, equipment selection, experimental design, and implementation strategies. These guidelines represent a DSR-based conceptual artifact to inform future empirical studies and support the structured assessment of immersive safety training interventions. The study also highlights the potential of integrating behavioral and physiological indicators to support immersive evaluations of behavioral change, offering an expert-informed and structured foundation for future empirical studies in high-risk industrial contexts. Full article
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40 pages, 14416 KB  
Review
Development Status of Production Purification and Casting and Rolling Technology of Electrical Aluminum Rod
by Xiaoyu Liu, Huixin Jin and Jiajun Jiang
Metals 2025, 15(9), 981; https://doi.org/10.3390/met15090981 (registering DOI) - 1 Sep 2025
Abstract
As the demand for lightweight and high-performance conductive materials grows in power transmission systems, aluminum alloy rods have emerged as a cost-effective and scalable alternative to copper conductors. This review systematically examines the development status and technological progress in the purification and casting–rolling [...] Read more.
As the demand for lightweight and high-performance conductive materials grows in power transmission systems, aluminum alloy rods have emerged as a cost-effective and scalable alternative to copper conductors. This review systematically examines the development status and technological progress in the purification and casting–rolling processes used in the production of Electrical Round Aluminum Rods (ERARs). It explores current challenges in improving electrical conductivity and mechanical strength while addressing issues such as hydrogen and oxide inclusion removal, grain refinement, and impurity segregation. Key purification techniques—including flux refining, gas treatment, filtration, and rotary injection—are compared in terms of performance, cost, and environmental impact. The paper also analyzes different casting–rolling methods, including continuous casting and rolling, twin-roll casting, and extrusion processes, with attention to process optimization and equipment design. Furthermore, emerging applications of artificial intelligence (AI) in predictive modeling, defect detection, and process parameter optimization are highlighted, offering a novel perspective on intelligent and sustainable ERAR production. This paper aims to provide insights for facilitating the industrial-scale production and performance enhancement of ERAR materials. Full article
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29 pages, 5378 KB  
Article
Methods for Rescuing People Using Climbing Equipment in Abandoned Mines to Be Carried Out by Rescue Units of the Integrated Rescue System
by Marek Szücs, Miroslav Betuš, Martin Konček, Marian Šofranko and Andrea Šofranková
Safety 2025, 11(3), 83; https://doi.org/10.3390/safety11030083 (registering DOI) - 1 Sep 2025
Abstract
This article discusses the possibilities and methods for rescuing people from abandoned mine workings and the cooperation of the components of the Integrated Rescue System of the Slovak Republic when carrying out rescue work in underground spaces, specifically the Bankov mine. Additionally, the [...] Read more.
This article discusses the possibilities and methods for rescuing people from abandoned mine workings and the cooperation of the components of the Integrated Rescue System of the Slovak Republic when carrying out rescue work in underground spaces, specifically the Bankov mine. Additionally, the basic legislative restrictions on the level of rescue work that can be performed in underground spaces in Slovakia and abroad are characterized. In the study itself, exercises in a mining environment were designed and tested by rescuers from the fire and rescue corps of the Slovak Republic, while several methods for rescuing people from underground spaces using climbing equipment were tested. Since the research setting was an abandoned mine, the rescue methods were carried out with regard to the maximum achievable safety of the firefighters. With the demise of the Mine Rescue Service in the Slovak Republic in 2025, rescue activities passed into the hands of the fire and rescue corps, and it is therefore necessary to determine the best method for rescue from mining spaces that can be performed by firefighters when the priority is the rescue time: the most important factor for saving human life. Using the analysis of the data obtained in this study, the most effective method specifically for rescuing people from underground spaces was determined. Based on the information obtained, proposals and measures were established to make rescue work in underground spaces more efficient. The research met all standards set for firefighters, and all rescuers agreed to publish this research. Full article
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33 pages, 66783 KB  
Article
Ship Rolling Bearing Fault Identification Under Complex Operating Conditions: Multi-Domain Feature Extraction-Based LCM-HO Enhanced LSSVM Approach
by Qiang Yuan, Jinzhi Peng, Xiaofei Wen, Zhihong Liu, Ruiping Zhou and Jun Ye
Sensors 2025, 25(17), 5400; https://doi.org/10.3390/s25175400 (registering DOI) - 1 Sep 2025
Abstract
With the continuous advancement of intelligent, integrated, and sophisticated modern marine equipment, bearing fault diagnosis faces increasingly severe technical challenges. Compared with traditional industrial environments, marine propulsion systems are characterized by multi-bearing coupled vibrations and complex operating conditions. To address these characteristics, this [...] Read more.
With the continuous advancement of intelligent, integrated, and sophisticated modern marine equipment, bearing fault diagnosis faces increasingly severe technical challenges. Compared with traditional industrial environments, marine propulsion systems are characterized by multi-bearing coupled vibrations and complex operating conditions. To address these characteristics, this paper proposes a fault diagnosis method that combines a least squares support vector machine (LSSVM) with multi-domain feature extraction based on an improved hippopotamus optimization algorithm (LCM-HO). This method directly extracts time, spectral, and time-frequency domain features from the raw signal, effectively avoiding complex preprocessing and enhancing its potential for field engineering applications. Experimental verification using the Paderborn bearing dataset and a self-built marine bearing test bench demonstrates that the LCM-HO-LSSVM method achieves diagnostic accuracy rates of 99.11% and 98.00%, respectively, demonstrating significant performance improvements. This research provides a reliable, efficient, and robust technical solution for bearing fault diagnosis in complex marine environments. Full article
(This article belongs to the Section Fault Diagnosis & Sensors)
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32 pages, 2359 KB  
Article
Exploring the Use and Misuse of Large Language Models
by Hezekiah Paul D. Valdez, Faranak Abri, Jade Webb and Thomas H. Austin
Information 2025, 16(9), 758; https://doi.org/10.3390/info16090758 (registering DOI) - 1 Sep 2025
Abstract
Language modeling has evolved from simple rule-based systems into complex assistants capable of tackling a multitude of tasks. State-of-the-art large language models (LLMs) are capable of scoring highly on proficiency benchmarks, and as a result have been deployed across industries to increase productivity [...] Read more.
Language modeling has evolved from simple rule-based systems into complex assistants capable of tackling a multitude of tasks. State-of-the-art large language models (LLMs) are capable of scoring highly on proficiency benchmarks, and as a result have been deployed across industries to increase productivity and convenience. However, the prolific nature of such tools has provided threat actors with the ability to leverage them for attack development. Our paper describes the current state of LLMs, their availability, and their role in benevolent and malicious applications. In addition, we propose how an LLM can be combined with text-to-speech (TTS) voice cloning to create a framework capable of carrying out social engineering attacks. Our case study analyzes the realism of two different open-source TTS models, Tortoise TTS and Coqui XTTS-v2, by calculating similarity scores between generated and real audio samples from four participants. Our results demonstrate that Tortoise is able to generate realistic voice clone audios for native English speaking males, which indicates that easily accessible resources can be leveraged to create deceptive social engineering attacks. As such tools become more advanced, defenses such as awareness, detection, and red teaming may not be able to keep up with dangerously equipped adversaries. Full article
15 pages, 2676 KB  
Article
Hyper-Localized Pollution Mapping Using Low-Cost Wearable Monitors and Citizen Science in Hong Kong
by Xiujie Li, Cheuk Ming Mak, Yuwei Dai, Kuen Wai Ma and Hai Ming Wong
Buildings 2025, 15(17), 3131; https://doi.org/10.3390/buildings15173131 (registering DOI) - 1 Sep 2025
Abstract
Low-cost sensors have demonstrated their advances in acquiring hyper-localized data compared to traditional, high-maintenance air quality monitoring stations. The study aims to leverage the mobility of participants equipped with low-cost wearable monitors (LWMs) by comparing their exposure to particulate matter (PM) across indoor-home, [...] Read more.
Low-cost sensors have demonstrated their advances in acquiring hyper-localized data compared to traditional, high-maintenance air quality monitoring stations. The study aims to leverage the mobility of participants equipped with low-cost wearable monitors (LWMs) by comparing their exposure to particulate matter (PM) across indoor-home, outdoor-walking, and hybrid-commuting micro-environments. The LWMs would be calibrated first through field co-location and the multiple linear regression models. The coefficient of determination (R2) of PM1.0 and PM2.5 increased to over 0.85 after calibration, along with the reduced root mean square error of 2.25 and 3.46 μg/m3, respectively. The 26-day PM data collection with geographic locations could identify individual exposure patterns, local source contributions, and hotspot maps. Commuting constituted a small fraction of daily time (4–8%) but contributed a disproportionate impact, accounting for 11% of individual PM exposure. Indoor-home PM2.5 exposure varied significantly among the urban districts. Based on the PM2.5 hotspot map, the elevated concentration was mainly concentrated in dense residential areas and historical industrial areas, as well as interchanges of major roads and the highway system. LWMs acting as non-regulatory instruments can complement monitoring stations to provide missing short-term and hyper-localized air pollution data. Future studies should integrate long-term monitoring and citizen science across seasons and geographical regions to address pollutant spatiotemporal variability for building and city sustainability. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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12 pages, 871 KB  
Article
Reverse Transcription Recombinase-Aided Amplification Assay for Newcastle Disease Virus in Poultry
by Nahed Yehia, Ahmed Abd El Wahed, Ahmed Abd Elhalem Mohamed, Abdelsattar Arafa, Dalia Said, Mohamed A. Shalaby, Arianna Ceruti, Uwe Truyen and Rea Maja Kobialka
Pathogens 2025, 14(9), 867; https://doi.org/10.3390/pathogens14090867 (registering DOI) - 1 Sep 2025
Abstract
Newcastle disease (ND) is a highly contagious and economically significant viral infection that affects poultry globally, with recurrent outbreaks occurring even among vaccinated flocks in Egypt. Caused by the Newcastle disease virus (NDV), the disease results in substantial losses due to high mortality [...] Read more.
Newcastle disease (ND) is a highly contagious and economically significant viral infection that affects poultry globally, with recurrent outbreaks occurring even among vaccinated flocks in Egypt. Caused by the Newcastle disease virus (NDV), the disease results in substantial losses due to high mortality rates, decreased productivity, and the imposition of trade restrictions. This study aimed to develop a rapid, sensitive, and field-deployable diagnostic assay based on real-time reverse transcription recombinase-aided amplification (RT-RAA) for the detection of all NDV genotypes in clinical avian specimens. Primers and an exo-probe were designed based on the most conserved region of the NDV matrix gene. After testing ten primer combinations, the pair NDV RAA-F1 and RAA-R5 demonstrated the highest sensitivity, detecting as low as 6.89 EID50/mL (95% CI). The RT-RAA assay showed excellent clinical sensitivity and specificity, with no cross-reactivity to other common respiratory pathogens such as avian influenza virus, infectious bronchitis virus, Mycoplasma gallisepticum or infectious laryngotracheitis virus. All 25 field samples that were tested positive by real-time RT-PCR, including those with high CT values (~35), were detected by RT-RAA in 2–11 min, indicating superior sensitivity and speed. The assay requires only basic equipment and can be performed under isothermal conditions, making it highly suitable for on-site detection in resource-limited or rural settings. The successful implementation of RT-RAA can improve NDV outbreak response, support timely vaccination strategies, and enhance disease control efforts. Overall, the assay presents a promising alternative to conventional diagnostic methods, contributing to the sustainability and productivity of the poultry sector in endemic regions. Full article
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17 pages, 2227 KB  
Article
Remaining Useful Life Prediction of Turbine Engines Using Multimodal Transfer Learning
by Jiaze Li and Zeliang Yang
Machines 2025, 13(9), 789; https://doi.org/10.3390/machines13090789 (registering DOI) - 1 Sep 2025
Abstract
Remaining useful life (RUL) prediction is a core technology in prognostics and health management (PHM), crucial for ensuring the safe and efficient operation of modern industrial systems. Although deep learning methods have shown potential in RUL prediction, they often face two major challenges: [...] Read more.
Remaining useful life (RUL) prediction is a core technology in prognostics and health management (PHM), crucial for ensuring the safe and efficient operation of modern industrial systems. Although deep learning methods have shown potential in RUL prediction, they often face two major challenges: an insufficient generalization ability when distribution gaps exist between training data and real-world application scenarios, and the difficulty of comprehensively capturing complex equipment degradation processes with single-modal data. A key challenge in current research is how to effectively fuse multimodal data and leverage transfer learning to address RUL prediction in small-sample and cross-condition scenarios. This paper proposes an innovative deep multimodal fine-tuning regression (DMFR) framework to address these issues. First, the DMFR framework utilizes a Convolutional Neural Network (CNN) and a Transformer Network to extract distinct modal features, thereby achieving a more comprehensive understanding of data degradation patterns. Second, a fusion layer is employed to seamlessly integrate these multimodal features, extracting fused information to identify latent features, which are subsequently utilized in the predictor. Third, a two-stage training algorithm combining supervised pre-training and fine-tuning is proposed to accomplish transfer alignment from the source domain to the target domain. This paper utilized the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) turbine engine dataset publicly released by NASA to conduct comparative transfer experiments on various RUL prediction methods. The experimental results demonstrate significant performance improvements across all tasks. Full article
(This article belongs to the Section Machines Testing and Maintenance)
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