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Keywords = federated cluster validation metric

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16 pages, 1066 KB  
Review
A Decade of Artificial Intelligence in Stroke Care (2015–2025): Trends, Clinical Translation, and the Precision Medicine Frontier—A Narrative Review
by Mian Urfy and Mariam Tariq Mir
J. Pers. Med. 2026, 16(4), 218; https://doi.org/10.3390/jpm16040218 - 16 Apr 2026
Viewed by 458
Abstract
Background/Objectives: Stroke generates 157 million disability-adjusted life-years (DALYs) annually, making it the leading neurological cause of global disease burden. Artificial intelligence (AI) and machine learning (ML) have emerged as transformative technologies across the stroke care continuum. This narrative review maps the trajectory of [...] Read more.
Background/Objectives: Stroke generates 157 million disability-adjusted life-years (DALYs) annually, making it the leading neurological cause of global disease burden. Artificial intelligence (AI) and machine learning (ML) have emerged as transformative technologies across the stroke care continuum. This narrative review maps the trajectory of AI in stroke medicine over the decade from 2015 to 2025. Methods: We conducted a narrative review with a structured, pre-specified search strategy across eight pre-specified thematic clusters using PubMed/MEDLINE (January 2015–December 2025), identifying 8549 records and including 1335 studies after screening. Inclusion criteria encompassed primary research articles, systematic reviews, meta-analyses, and RCTs reporting quantitative performance metrics or clinical outcome data for AI/ML in stroke. Results: Stroke imaging AI is the most commercially mature domain, with over 30 FDA-cleared tools. Automated ASPECTS scoring reduced radiologist reading time by 74.8% (AUC 84.97%; 95% CI: 83.1–86.8%). The only triage AI RCT demonstrated an 11.2 min reduction in door-to-groin time without significant improvement in 90-day functional independence (OR 1.3, 95% CI 0.42–4.0). Brain–computer interface rehabilitation showed significant upper limb recovery in a 17-center RCT (FMA-UE mean difference +3.35 points, 95% CI 1.05–5.65; p = 0.0045). AF detection AI is FDA-cleared and RCT-validated. LLMs and federated learning are pre-regulatory but growing exponentially. Conclusions: AI in stroke has achieved diagnostic maturity but therapeutic immaturity. Bridging algorithmic performance to patient outcomes, addressing equity gaps, and building the economic evidence base for scalable deployment are the defining challenges of the next decade. Full article
(This article belongs to the Special Issue Advances in Ischemic Stroke Management: Toward Precision Medicine)
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22 pages, 1664 KB  
Article
A Blockchain-Enabled Decentralized Zero-Trust Architecture for Anomaly Detection in Satellite Networks via Post-Quantum Cryptography and Federated Learning
by Sridhar Varadala and Hao Xu
Future Internet 2025, 17(11), 516; https://doi.org/10.3390/fi17110516 - 12 Nov 2025
Viewed by 1181
Abstract
The rapid expansion of satellite networks for advanced communication and space exploration has ensured that robust cybersecurity for inter-satellite links has become a critical challenge. Traditional security models rely on centralized trust authorities, and node-specific protections are no longer sufficient, particularly when system [...] Read more.
The rapid expansion of satellite networks for advanced communication and space exploration has ensured that robust cybersecurity for inter-satellite links has become a critical challenge. Traditional security models rely on centralized trust authorities, and node-specific protections are no longer sufficient, particularly when system failures or attacks affect groups of satellites or agent clusters. To address this problem, we propose a blockchain-enabled decentralized zero-trust model based on post-quantum cryptography (BEDZTM-PQC) to improve the security of satellite communications via continuous authentication and anomaly detection. This model introduces a group-based security framework, where satellite teams operate under a zero-trust architecture (ZTA) enforced by blockchain smart contracts and threshold cryptographic mechanisms. Each group shares the responsibility for local anomaly detection and policy enforcement while maintaining decentralized coordination through hierarchical federated learning, allowing for collaborative model training without centralizing sensitive telemetry data. A post-quantum cryptography (PQC) algorithm is employed for future-proof communication and authentication protocols against quantum computing threats. Furthermore, the system enhances network reliability by incorporating redundant communication channels, consensus-based anomaly validation, and group trust scoring, thus eliminating single points of failure at both the node and team levels. The proposed BEDZTM-PQC is implemented in MATLAB, and its performance is evaluated using key metrics, including accuracy, latency, security robustness, trust management, anomaly detection accuracy, performance scalability, and security rate with respect to different numbers of input satellite users. Full article
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18 pages, 2689 KB  
Article
Blockchain-Enabled, Nature-Inspired Federated Learning for Cattle Health Monitoring
by Lakshmi Prabha Ganesan and Saravanan Krishnan
Informatics 2025, 12(3), 57; https://doi.org/10.3390/informatics12030057 - 20 Jun 2025
Cited by 1 | Viewed by 1824
Abstract
Traditional cattle health monitoring systems rely on centralized data collection, posing significant challenges related to data privacy, network connectivity, model reliability, and trust. This study introduces a novel, nature-inspired federated learning (FL) framework for cattle health monitoring, integrating blockchain to ensure model validation, [...] Read more.
Traditional cattle health monitoring systems rely on centralized data collection, posing significant challenges related to data privacy, network connectivity, model reliability, and trust. This study introduces a novel, nature-inspired federated learning (FL) framework for cattle health monitoring, integrating blockchain to ensure model validation, system resilience, and reputation management. Inspired by the fission–fusion dynamics of elephant herds, the framework adaptively forms and merges subgroups of edge nodes based on six key parameters: health metrics, activity levels, geographical proximity, resource availability, temporal activity, and network connectivity. Graph attention networks (GATs) enable dynamic fission, while Density-Based Spatial Clustering of Applications with Noise (DBSCAN) supports subgroup fusion based on model similarity. Blockchain smart contracts validate model contributions and ensure that only high-performing models participate in global aggregation. A reputation-driven mechanism promotes reliable nodes and discourages unstable participants. Experimental results show the proposed framework achieves 94.3% model accuracy, faster convergence, and improved resource efficiency. This adaptive and privacy-preserving approach transforms cattle health monitoring into a more trustworthy, efficient, and resilient process. Full article
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14 pages, 1333 KB  
Article
Elastic Balancing of Communication Efficiency and Performance in Federated Learning with Staged Clustering
by Ying Zhou, Fang Cui, Junlin Che, Mao Ni, Zhiyuan Zhang and Jundi Li
Electronics 2025, 14(4), 745; https://doi.org/10.3390/electronics14040745 - 14 Feb 2025
Cited by 2 | Viewed by 1348
Abstract
Clustered federated learning has garnered significant attention as an effective strategy for enhancing model performance in non-independent and identically distributed (non-IID) data scenarios. This approach improves model performance in such environments by calculating the similarity between users and clustering them into multiple groups. [...] Read more.
Clustered federated learning has garnered significant attention as an effective strategy for enhancing model performance in non-independent and identically distributed (non-IID) data scenarios. This approach improves model performance in such environments by calculating the similarity between users and clustering them into multiple groups. However, several challenges arise when implementing this method, particularly in balancing flexibility, communication costs, and model performance. To address these issues, this paper proposes a novel hierarchical federated learning framework that balances both network and model performance. The framework performs principal component analysis (PCA) on device-side image datasets to assess the similarity of private data across devices and, in conjunction with network performance measurements, dynamically adjusts communication strategies to minimize latency while ensuring stable model performance. By weighting similarity and communication metrics, the framework optimizes communication efficiency without significantly compromising model performance. To validate the proposed method’s effectiveness, we employed three publicly available datasets and compared it against four baseline methods. The experimental results demonstrate that SC-Fed (segmented clustering-federated learning) achieves a maximum accuracy improvement of 7.56% over baseline methods, while also reducing the average waiting time by 54.6%. These results indicate that the proposed algorithm significantly enhances the applicability and efficiency of clustered federated learning in practical training scenarios. Full article
(This article belongs to the Special Issue Network Security Management in Heterogeneous Networks)
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21 pages, 683 KB  
Article
On a Framework for Federated Cluster Analysis
by Morris Stallmann and Anna Wilbik
Appl. Sci. 2022, 12(20), 10455; https://doi.org/10.3390/app122010455 - 17 Oct 2022
Cited by 15 | Viewed by 3668
Abstract
Federated learning is becoming increasingly popular to enable automated learning in distributed networks of autonomous partners without sharing raw data. Many works focus on supervised learning, while the area of federated unsupervised learning, similar to federated clustering, is still less explored. In this [...] Read more.
Federated learning is becoming increasingly popular to enable automated learning in distributed networks of autonomous partners without sharing raw data. Many works focus on supervised learning, while the area of federated unsupervised learning, similar to federated clustering, is still less explored. In this paper, we introduce a federated clustering framework that solves three challenges: determine the number of global clusters in a federated dataset, obtain a partition of the data via a federated fuzzy c-means algorithm, and validate the clustering through a federated fuzzy Davies–Bouldin index. The complete framework is evaluated through numerical experiments on artificial and real-world datasets. The observed results are promising, as in most cases the federated clustering framework’s results are consistent with its nonfederated equivalent. Moreover, we embed an alternative federated fuzzy c-means formulation into our framework and observe that our formulation is more reliable in case the data are noni.i.d., while the performance is on par in the i.i.d. case. Full article
(This article belongs to the Special Issue Federated and Transfer Learning Applications)
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