Search Results (160)

Ro-Ro (Roll-on/Roll-off) vessels require adaptable deck systems to efficiently accommodate vehicles of varying sizes. Conventional fixed or hydraulically lifted car decks often face challenges related to structural efficiency, maintainability, and limited flexibility. To address these issues, this study proposes a novel hoistable car deck system that incorporates a hinge-based folding mechanism and modular connections. The design enhances maintainability, allows independent adjustment of deck panels without external lifting equipment, and improves adaptability to diverse ship layouts. In addition, the proposed concept was systematically evaluated to verify its structural integrity and serviceability under representative loading conditions, highlighting its compliance with classification society requirements. These results suggest that the hinge-based modular deck provides a promising solution for next-generation Ro-Ro vessels, offering both operational flexibility and improved efficiency while paving the way for practical applications in shipbuilding and retrofitting projects. Full article

The operational performance of Flexible Hinge Piezoelectric Stages (FHPSs), essential components in precision engineering, is fundamentally constrained by the inherent hysteresis of the piezoelectric actuator (PEA). A significant deficiency in prevailing characterization methods is their failure to consider the dynamic nature of the mechanical preload exerted by the flexible hinge. This position-dependent preload induces substantial deviations in the PEA’s response characteristics, thereby compromising the predictive accuracy of conventional design frameworks. To address this limitation, this paper proposes a Force-Dependent Prandtl–Ishlinskii (FPI) model that explicitly formulates the PEA’s hysteretic behavior as a function of variable preload conditions. The FPI model is subsequently integrated into a comprehensive FPI-FFEM characterization framework. Within this framework, a Force-analyzed Finite Element Method (FFEM) is utilized to compute the dynamic preload throughout the actuator’s operational stroke. This information, notably neglected in conventional FEM analysis, is essential to the fidelity of the proposed FPI model. Experimental validation demonstrates the superior fidelity of the FPI model in comparison to the traditional PI model for tracking preload-induced nonlinearities. Furthermore, the complete FPI-FFEM framework exhibits substantially enhanced prediction accuracy relative to both conventional PI-FEM and advanced LDPI-FEM methodologies, as demonstrated by a significant reduction in the Mean Absolute Error (MAE). Full article

Steel structures with base-hinged columns are one of the typical forms adopted for rural housing in villages and towns due to their superior seismic resistance, energy efficiency, and environmental benefits. The lateral bracing system plays a crucial role in the ability of steel frames with base-hinged columns to resist horizontal forces. This study investigates the impact of rigid and flexible bracing on the seismic performance of such structures, emphasizing that enhanced ductility—particularly in flexibly braced frames—is essential for seismic resilience in earthquake-prone areas. Two full-scale steel frame models, one with rigid bracing and the other with flexible bracing, were fabricated based on typical rural housing designs and subjected to low-cycle reversed loading tests. The results indicate that the rigidly braced frame undergoes brittle failure, characterized by fractures and buckling at bracing intersections. In contrast, the flexibly braced frame exhibits ductile failure, identified by the bending deformation of tension rods. Despite the flexibly braced frame reaching a peak-load bearing capacity that is only 69.1% (positive direction) and 76.0% (negative direction) of the rigidly braced frame, it achieves ultimate displacements 2.7 times (positive direction) and 2.5 times (negative direction) greater. Additionally, the flexibly braced frame exhibits a stable energy dissipation capacity, with cumulative energy dissipation 1.49 times that of the rigidly braced frame. Numerical simulations were conducted to develop finite element models for both rigidly and flexibly braced frames. The resulting failure characteristics and bearing capacities of the frames were obtained, providing further validation of the experimental results. These findings provide data-supported evidence for promoting steel structures with base-hinged columns in rural housing applications. Full article

The HIV-1 aspartic protease is an effective target for the treatment of HIV/AIDS. Current therapy utilizes a selection of nine protease inhibitors (PIs) in combination with other classes of antiretroviral drugs. Although PIs were originally developed based on the knowledge of the HIV-1 subtype B protease, the existence of other HIV-1 subtypes and the effects of drug resistance on currently available PIs have become a major challenge in the treatment of HIV/AIDS. Specifically, the HIV-1 subtype C accounts for more than half of the global HIV infections. Considering the importance and relevance of the subtype C virus, in this timely review we discuss the effect of polymorphisms in the HIV-1 subtype C protease on drug resistance, flap flexibility, and hinge region dynamics. We discuss novel paradigms of protease inhibition that attempt to overcome the limitations of currently available inhibitors which fall short considering genetic diversity and resistance mutations. Full article

With the acceleration of industrialization, deformable mechanisms that can adapt to complex environments have gained widespread applications. Joints serve as carriers for transmitting forces and motions between components, and their stiffness significantly influences the static and dynamic characteristics of deformable mechanisms. A variable stiffness joint is crucial for ensuring the safety and reliability of the system, as well as for enhancing environmental adaptability. However, existing variable stiffness joints fail to meet the requirements for miniaturization, lightweight construction, and fast response. This paper proposes a piezoelectric-actuated variable stiffness miniature rotary joint featuring a compact structure, monitorable loading state, and rapid response. Given that the piezoelectric stack expands and contracts when energized, this paper proposes a transmission principle for stiffness adjustment by varying the pressure and friction between active and passive components. This joint utilizes a flexible hinge mechanism for displacement amplification and incorporates a torque sensor based on strain monitoring. A static model is developed based on piezoelectric equations and displacement amplification characteristics, and simulations confirm the feasibility of the stiffness adjustment scheme. The mechanical characteristics of various flexible hinge structures are analyzed, and the effects of piezoelectric actuation capability and external load on stiffness adjustment are examined. The experimental results demonstrate that the joint can adjust stiffness, and the sensor is calibrated using the least squares algorithm to monitor the stress state of the joint in real time. Full article

This study introduces a rigid–flexible coupled constant force actuator integrated with Active Disturbance Rejection Control (ADRC) to tackle the rigidity–compliance trade-off in precision force-sensitive applications. The actuator utilizes compliant hinges to decrease contact stiffness by three orders of magnitude (${10}^6\to {10}^3 \mathrm{N}/\mathrm{m}$), facilitating effective force management through millimeter-scale placement (0.1∼1 mm) and inherently mitigating high-frequency disturbances. The ADRC framework, augmented by an Extended State Observer (ESO), dynamically assesses and compensates for internal nonlinearities (such as friction hysteresis) and external disturbances without necessitating accurate system models. Experimental results indicate enhanced performance compared to PID control: under dynamic disturbances, force deviations are limited to $\pm 0.2 \mathrm{N}$ with a 98.5% reduction in mean absolute error, a 96.3% increase in settling speed, and 99% suppression of oscillations. The co-design of mechanical compliance with model-free control addresses the constraints of traditional high-stiffness systems, providing a scalable solution for industrial robots, compliant material processing, and medical device operations. Validation of the prototype under sinusoidal perturbations demonstrates reliable force regulation (settling time $<0.56 \mathrm{s}$, errors $<0.5 \mathrm{N}$), underscoring its relevance in dynamic situations. This study integrates theoretical innovation with experimental precision, enhancing intelligent manufacturing systems via adaptive control and structural synergy. Full article

This paper addresses inherent limitations in unmanned aerial vehicle (UAV) undercarriages hindering vertical takeoff and landing (VTOL) capabilities on uneven slopes and obstacles. Robotic landing gear (RLG) designs have been proposed to address these limitations; however, existing designs are typically limited to ground slopes of 6–15°, beyond which rollover would happen. Moreover, articulated RLG concepts come with added complexity and weight penalties due to multiple drivetrain components. Previous research has highlighted that even a minor 3-degree slope change can increase the dynamic rollover risks by 40%. Therefore, the design optimization of robotic landing gear for enhanced VTOL capabilities requires a multidisciplinary framework that integrates static analysis, dynamic simulation, and control strategies for operations on complex terrain. This paper presents a novel, hybrid, compliant, belt-driven, three-legged RLG system, supported by a multidisciplinary design optimization (MDO) methodology, aimed at achieving enhanced VTOL capabilities on uneven surfaces and moving platforms like ship decks. The proposed system design utilizes compliant mechanisms featuring a series of three-flexure hinges (3SFH), to reduce the number of articulated drivetrain components and actuators. This results in a lower system weight, improved energy efficiency, and enhanced durability, compared to earlier fully actuated, articulated, four-legged, two-jointed designs. Additionally, the compliant belt-driven actuation mitigates issues such as backlash, wear, and high maintenance, while enabling smoother torque transfer and improved vibration damping relative to earlier three-legged cable-driven four-bar link RLG systems. The use of lightweight yet strong materials—aluminum and titanium—enables the legs to bend 19 and 26.57°, respectively, without failure. An animated simulation of full-contact landing tests, performed using a proportional-derivative (PD) controller and ship deck motion input, validate the performance of the design. Simulations are performed for a VTOL UAV, with two flexible legs made of aluminum, incorporating circular flexure hinges, and a passive third one positioned at the tail. The simulation results confirm stable landings with a 2 s settling time and only 2.29° of overshoot, well within the FAA-recommended maximum roll angle of 2.9°. Compared to the single-revolute (1R) model, the implementation of the optimal 3R Pseudo-Rigid-Body Model (PRBM) further improves accuracy by achieving a maximum tip deflection error of only 1.2%. It is anticipated that the proposed hybrid design would also offer improved durability and ease of maintenance, thereby enhancing functionality and safety in comparison with existing robotic landing gear systems. Full article

Solving the common paradoxical problem between sub-micro-arc level resolution and a wide range of rotation angles in rotary actuators, this paper designs a single-drive compliant rotary mechanism (CRM) and develops a cross-scale compliant rotary actuator (CCRA). Specially, the proposed CRM employs a single-input–four-output divergent parallel configuration to transform a unidirectional input force into a rotational moment around the rotational center, effectively avoiding asynchronous motion and rotational center shift caused by the multiple actuation. Moreover, the CCRA is developed based on the CRM and a direct-drive rotary (DDR) motor, and adaptive switching between the macro- and micro-combination can simultaneously achieve large rotary range and sub-µrad resolution. After a series of modeling, mechanism optimization, and simulation, a prototype experimental system was built to further test the performance of proposed CCRA. The open-loop and closed-loop characterization experiments showed that the CRM can achieve a rotational resolution of 0.05 $\mathsf{\mu }$rad and a driving force of 0.78 N·m. In addition, the cross-scale switching experimental results show that the CCRA is able to achieve a static positioning accuracy of 3.5 $\mathsf{\mu }$rad within a $\pm 5^{\circ }$ rotational range. Full article

The Dynamic Stiffness Matrix (DSM) of a structure is a frequency-dependent stiffness matrix relating the actions (forces and moments) and displacements (translations and rotations) when the structure vibrates at a given frequency. The DSM may be used to find the natural frequencies, modes, and structural response. For many structures, including skeletal frames of prismatic members, exact transcendental expressions for the DSM are readily available. This paper presents a mathematical proof of a linear determinantal relationship between the DSM of a skeletal frame when it is undamaged, cracked, and hinged at the crack location. The rotational stiffness or flexibility of the crack also appears as a linear term. This relationship gives, for the first time, an explicit equation to directly calculate the stiffness of the rotational spring representing a crack from measured natural frequencies for any potential crack location. Numerical examples demonstrate that computing the DSM of the intact and hinged structures gives an efficient solution method for the inverse problem of identifying crack location and severity. This paper also shows that an approximate DSM based on a finite element model can be used in the same way, making this procedure more versatile. Furthermore, new approximate expressions for the natural frequencies of structures with very small or very severe cracks are derived. An interesting relationship between the square of the bending moment in an undamaged beam and the determinant of the DSM of a hinged beam is also derived. This relationship, which can also be inferred from previous work, leads to a better understanding of the effect of crack location in specific vibration modes. Full article

Traditional reversible data hiding (RDH) methods prioritize the exact recovery of the original cover image; however, this rigidity often hinders both capacity and design flexibility. This study introduces a partial reversible data hiding (PRDH) framework that departs from conventional standards by allowing reversibility relative to a generated cover image rather than the original. The proposed system leverages a dual-image structure and an enhanced HC(7,4) Hamming code to synthesize virtual pixels, enabling efficient and low-distortion syndrome-based encoding. Notably, it achieves embedding rates up to 1.5 bpp with PSNR values exceeding 48 dB. While the proposed method avoids auxiliary data, its reliability hinges on paired image availability, which is a consideration for real-world deployment. Demonstrated resilience to RS-based steganalysis suggests viability in sensitive domains such as embedding structured metadata in diagnostic medical imagery. Nonetheless, further evaluation across more diverse image types and attack scenarios is necessary in order to confirm its generalizability. Full article

Insect flight mechanisms are highly efficient and involve complex hinge structures that facilitate amplified wing movement through thoracic deformation. However, in the field of flapping-wing robots, the replication of thoracic skeletal structures has received little attention. In this study, we propose and compare two different hinge models inspired by insect flight: an elastic hinge model (EHM) and an axle hinge model (AHM). Both models were fabricated using 3D printing technology using PLA material. The EHM incorporates flexible structures in both the hinge and lateral scutum regions, allowing for deformation-driven wing motion. In contrast, the AHM employs metal pins in the hinge region to reproduce joint-like articulation, while still permitting elastic deformation in the lateral scutum. To evaluate their performance, we employed an SMA actuator to generate flapping motion, and measured the wing displacement, flapping frequency, and exoskeletal deformation. The experimental results demonstrate that the EHM achieves wing flapping through overall structural flexibility, whereas the AHM provides more defined hinge motion while maintaining exoskeletal elasticity. These findings contribute to our understanding of the role of hinge mechanics in bioinspired flapping-wing robots. Future research will focus on optimizing these mechanisms for higher frequency operation, weight reduction, and better energy efficiency. Full article

Molecular imaging probes play a pivotal role in assaying molecular events in various physiological systems. In this study, we demonstrate a new genre of bioluminescent probes for imaging protein–protein interactions (PPIs) in mammalian cells, named the molecular association assay (MAA) probe. The MAA probe is designed to be as simple as a full-length marine luciferase fused to a protein of interest with a flexible linker. This simple fusion protein alone surprisingly works by recognizing a specific ligand, interacting with a counterpart protein of the PPI, and developing bioluminescence (BL) in mammalian cells. We made use of an artificial intelligence (AI) tool to simulate the binding modes and working mechanisms. Our AlphaFold-based analysis on the binding mode suggests that the hinge region of the MAA probe is flexible before ligand binding but becomes stiff after ligand binding and protein association. The sensorial properties of representative MAA probes, FRB-ALuc23 and FRB-R86SG, are characterized with respect to the quantitative feature, BL spectrum, and in vivo tumor imaging using xenografted mice. Our AI-based simulation of the working mechanisms reveals that the association of MAA probes with the other proteins works in a way to facilitate the substrate’s access to the active sites of the luciferase (ALuc23 or R86SG). We prove that the concept of MAA is generally applicable to other examples, such as the ALuc16- or R86SG-fused estrogen receptor ligand-binding domain (ER LBD). Considering the versatility of this conceptionally unique and distinctive molecular imaging probe compared to conventional ones, we are expecting the widespread application of these probes as a new imaging repertoire to determine PPIs in living organisms. Full article

The workspace of the compliant parallel mechanism (CPM) is generally limited due to the small deformation range of flexible hinges, which are usually at the micro/nano scale. This paper takes the 2-DOFs n-4R compliant parallel pointing mechanism (n-4R CPPM) as the object and optimizes the workspace performance of the mechanism through redundant actuation, aiming to maximize the workspace. First, the kinetostatic model and the flexible hinge displacement model of the redundant actuated n-4R CPPM are established, successively. The former model reveals the relationships between the output displacements and the input forces/displacements, while the latter relates the flexible hinge deformation and the input forces/displacements. Second, a space pointing trajectory is chosen to validate the accuracy of the kinetostatic model of the redundant actuated 3-4R CPPM through finite element (FE) simulation. The results show that the relative error between the analytical and the FE results does not exceed 2.1%, and the high consistency indicates the accuracy of the kinetostatic model. Finally, the workspace performance of the 3-4R and 4-4R CPPMs is successively optimized through redundant actuation. The results indicate that, compared with the non-redundant actuation case, the workspace can be effectively enlarged and become more symmetric by means of the redundant actuation. The maximum achievable pitch angle ψ_a and the y-direction motion range of the mobile platform both increase by 100%. Moreover, it is shown that the workspace in the non-redundant actuated case is a subset of the workspace in the redundant actuated case, and the position-workspace shape changes from planar to 3-D. Full article

Micro Light Emitting Diode (Micro-LED) technology, characterized by exceptional brightness, low power consumption, fast response, and long lifespan, holds significant potential for next-generation displays, yet its commercialization hinges on resolving challenges in high-density interconnect fabrication, particularly micrometer-scale bump formation. Traditional fabrication approaches such as evaporation enable precise bump control but face scalability and cost limitations, while electroplating offers lower costs and higher throughput but suffers from substrate conductivity requirements and uneven current density distributions that compromise bump-height uniformity. Emerging alternatives include electroless plating, which achieves uniform metal deposition on non-conductive substrates through autocatalytic reactions albeit with slower deposition rates; ball mounting and dip soldering, which streamline processes via automated solder jetting or alloy immersion but struggle with bump miniaturization and low yield; and photosensitive conductive polymers that simplify fabrication via photolithography-patterned composites but lack validated long-term stability. Persistent challenges in achieving micrometer-scale uniformity, thermomechanical stability, and environmental compatibility underscore the need for integrated hybrid processes, eco-friendly manufacturing protocols, and novel material innovations to enable ultra-high-resolution and flexible Micro-LED implementations. This review systematically compares conventional and emerging methodologies, identifies critical technological bottlenecks, and proposes strategic guidelines for industrial-scale production of high-density Micro-LED displays. Full article

Leaf spring-type flexible hinges serve as critical transmission components in kilogram quantization energy balance systems. Investigating their bending behavior is crucial for enhancing measurement accuracy and ensuring structural reliability. This work employs molecular dynamics simulations to analyze the mechanical properties and deformation characteristics of such hinges under varying bending rates. The findings reveal a significant correlation between the bending rate and the hinges’ plastic deformation and microstructural evolution, indicating the presence of a critical bending rate. When the bending rate is below the critical threshold, the hinges exhibit excellent structural stability, characterized by low dislocation density, reduced von Mises stress, and limited temperature rise, making them suitable for long-term use. Conversely, when the bending rate exceeds the critical threshold, the hinges undergo significant plastic deformation, including notable increases in stress and temperature concentration, as well as microstructural alterations. Specifically, the initially stable crystal structure is disrupted, leading to the formation of numerous defect structures. These changes result in localized instability and elevate the risk of fatigue damage. This work comprehensively elucidates the mechanical responses and failure mechanisms of flexible hinges, providing valuable data and guidance for their optimized design and application. Full article