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  • Article
  • Open Access
7 Citations
4,063 Views
14 Pages

Do Maternal Factors and Milk Expression Patterns Affect the Composition of Donor Human Milk?

  • Agnieszka Bzikowska-Jura,
  • Natalia Machaj,
  • Piotr Sobieraj,
  • Olga Barbarska,
  • Gabriela Olędzka and
  • Aleksandra Wesolowska

15 July 2021

A primary role of Human Milk Banks (HMBs) is to provide human milk (HM) for preterm infants and to support the mothers of these infants as they establish their own milk supply. A better understanding of the variation in the energy and macronutrients...

  • Feature Paper
  • Article
  • Open Access
144 Citations
23,185 Views
15 Pages

Maternal Nutrition and Body Composition During Breastfeeding: Association with Human Milk Composition

  • Agnieszka Bzikowska-Jura,
  • Aneta Czerwonogrodzka-Senczyna,
  • Gabriela Olędzka,
  • Dorota Szostak-Węgierek,
  • Halina Weker and
  • Aleksandra Wesołowska

27 September 2018

The composition of human milk is dynamic and can vary according to many maternal factors, such as diet and nutritional status. This study investigated the association of maternal nutrition and body composition with human milk composition. All measure...

  • Article
  • Open Access
50 Citations
6,645 Views
28 Pages

Human Milk Oligosaccharides and Bacterial Profile Modulate Infant Body Composition during Exclusive Breastfeeding

  • Ali S. Cheema,
  • Zoya Gridneva,
  • Annalee J. Furst,
  • Ana S. Roman,
  • Michelle L. Trevenen,
  • Berwin A. Turlach,
  • Ching T. Lai,
  • Lisa F. Stinson,
  • Lars Bode and
  • Donna T. Geddes
  • + 1 author

Human milk is a complex and variable ecosystem fundamental to the development of newborns. This study aimed to investigate relationships between human milk oligosaccharides (HMO) and human milk bacterial profiles and infant body composition. Human mi...

  • Article
  • Open Access
24 Citations
4,624 Views
16 Pages

27 March 2020

Commercial formula milk (FM) constitutes the best alternative to fulfill the nutritional requirements of infants when breastfeeding is precluded. Here, we present the comparative study of polar metabolite composition of human breast milk (HBM) and se...

  • Article
  • Open Access
4 Citations
3,416 Views
16 Pages

Human Milk Oligosaccharides, Growth, and Body Composition in Very Preterm Infants

  • Margaret L. Ong,
  • Sara Cherkerzian,
  • Katherine A. Bell,
  • Paige K. Berger,
  • Annalee Furst,
  • Kristija Sejane,
  • Lars Bode and
  • Mandy B. Belfort

18 April 2024

Human milk oligosaccharides (HMOs) are bioactive factors that benefit neonatal health, but little is known about effects on growth in very preterm infants (<32 weeks’ gestation). We aimed to quantify HMO concentrations in human milk fed to v...

  • Article
  • Open Access
15 Citations
4,184 Views
16 Pages

Total Fatty Acid and Polar Lipid Species Composition of Human Milk

  • Talat Bashir Ahmed,
  • Merete Eggesbø,
  • Rachel Criswell,
  • Olaf Uhl,
  • Hans Demmelmair and
  • Berthold Koletzko

29 December 2021

Human milk lipids are essential for infant health. However, little is known about the relationship between total milk fatty acid (FA) composition and polar lipid species composition. Therefore, we aimed to characterize the relationship between the FA...

  • Article
  • Open Access
8 Citations
3,431 Views
10 Pages

What Are the Maternal Factors that Potentially Intervenes in the Nutritional Composition of Human Milk?

  • Yasmin Amaral,
  • Leila Silva,
  • Fernanda Soares,
  • Daniele Marano,
  • Sylvia Nehab,
  • Andrea Abranches,
  • Ana Carolina Costa and
  • Maria Elisabeth Moreira

10 May 2021

Background: To evaluate the potential factors associated with the nutritional composition of human milk of puerperal women. Methods: cross-sectional study, conducted between March 2016 and August 2017, with 107 women, selected in a Tertiary Health Ca...

  • Protocol
  • Open Access
15 Citations
8,107 Views
10 Pages

Maternal Health and Nutrition Status, Human Milk Composition, and Growth and Development of Infants and Children: A Prospective Japanese Human Milk Study Protocol

  • Keisuke Nojiri,
  • Shunjiro Kobayashi,
  • Satoshi Higurashi,
  • Tomoki Takahashi,
  • Yuta Tsujimori,
  • Hiroshi M. Ueno,
  • Shiomi Watanabe-Matsuhashi,
  • Yasuhiro Toba,
  • Junichi Yamamura and
  • Toshiya Kobayashi
  • + 2 authors

It is unknown whether maternal health and nutrition are related to human milk composition or growth and development of infants and children. Here, we describe a protocol for a prospective five-year cohort study to clarify (i) how maternal health and...

  • Review
  • Open Access
18 Citations
6,947 Views
50 Pages

Relationships between the Intakes of Human Milk Components and Body Composition of Breastfed Infants: A Systematic Review

  • Isabella Norrish,
  • Azhar Sindi,
  • Vanessa S. Sakalidis,
  • Ching Tat Lai,
  • Jacki L. McEachran,
  • Mya Thway Tint,
  • Sharon L. Perrella,
  • Mark P. Nicol,
  • Zoya Gridneva and
  • Donna T. Geddes

18 May 2023

Human milk provides all of the elements necessary for infant growth and development. Previous studies have reported associations between breastfeeding and a reduced risk of developing obesity and late-onset metabolic disorders; however, the underlyin...

  • Article
  • Open Access
50 Citations
6,973 Views
14 Pages

Impact of Infant and Maternal Factors on Energy and Macronutrient Composition of Human Milk

  • Agnieszka Bzikowska-Jura,
  • Piotr Sobieraj,
  • Dorota Szostak-Węgierek and
  • Aleksandra Wesołowska

26 August 2020

The present study investigates the influence of selected infant and maternal factors on the energy and macronutrient composition of mature human milk (HM). The study enrolled 77 mothers at 4–8 weeks postpartum. Each mother provided 1 sample of...

  • Review
  • Open Access
85 Citations
11,701 Views
12 Pages

Human Milk Feeding and Preterm Infants’ Growth and Body Composition: A Literature Review

  • Jacopo Cerasani,
  • Federica Ceroni,
  • Valentina De Cosmi,
  • Alessandra Mazzocchi,
  • Daniela Morniroli,
  • Paola Roggero,
  • Fabio Mosca,
  • Carlo Agostoni and
  • Maria Lorella Giannì

21 April 2020

Preterm infants may show a higher risk of adverse health outcomes, such as the development of metabolic syndrome and cognitive impairment. The most recent evidence highlights that nutrition, body composition development, and early postnatal growth ma...

  • Article
  • Open Access
12 Citations
4,099 Views
12 Pages

Gestational Hypertension and Human Breast Milk Composition in Correlation with the Assessment of Fetal Growth—A Pilot Study

  • Ewa Magdalena Sokołowska,
  • Joanna Maria Jassem-Bobowicz,
  • Izabela Drążkowska,
  • Zuzanna Świąder and
  • Iwona Domżalska-Popadiuk

21 May 2023

Background and aims: 1 in 10 pregnant women is diagnosed with gestational hypertension. Increasing evidence suggests that preeclampsia, gestational diabetes and gestational hypertension may affect human breast milk’s lactogenesis and percentage...

  • Article
  • Open Access
2 Citations
3,242 Views
10 Pages

The Impacts of Single Preterm Human Donor Milk Compared to Mother’s Own Milk on Growth and Body Composition

  • Alexandra Thajer,
  • Esther Teunissen,
  • Theresa Kainz,
  • Elisabeth Calek,
  • Karin Harreiter,
  • Angelika Berger and
  • Christoph Binder

24 March 2023

(1) If mother´s own milk (MOM) is not available, pooled term human donor milk (HDM) is commonly used. Compared to MOM, term HDM contains less protein and fat and is associated with impaired growth. HDM from mothers of preterm infants is an alte...

  • Article
  • Open Access
27 Citations
6,475 Views
10 Pages

Does Human Milk Modulate Body Composition in Late Preterm Infants at Term-Corrected Age?

  • Maria Lorella Giannì,
  • Dario Consonni,
  • Nadia Liotto,
  • Paola Roggero,
  • Laura Morlacchi,
  • Pasqua Piemontese,
  • Camilla Menis and
  • Fabio Mosca

23 October 2016

(1) Background: Late preterm infants account for the majority of preterm births and are at risk of altered body composition. Because body composition modulates later health outcomes and human milk is recommended as the normal method for infant feedin...

  • Article
  • Open Access
1 Citations
2,216 Views
12 Pages

17 April 2025

Background/Objectives: Very preterm body composition at term shows potential as a biomarker of later health outcomes, but effects from in-hospital formula versus human milk (HM) (maternal milk (MM) and/or pasteurised human donor milk (DM) supplement)...

  • Article
  • Open Access
21 Citations
6,758 Views
13 Pages

Changes in Human Milk Fatty Acid Composition during Lactation: The Ulm SPATZ Health Study

  • Linda P. Siziba,
  • Leonie Lorenz,
  • Bernd Stahl,
  • Marko Mank,
  • Tamas Marosvölgyi,
  • Tamas Decsi,
  • Dietrich Rothenbacher and
  • Jon Genuneit

20 November 2019

The lipid fraction of human milk provides the infant with the fatty acids that are necessary for optimal growth and development. The aim of this study was to investigate the fatty acid composition of human milk at three time points during lactation a...

  • Abstract
  • Open Access
1,427 Views
2 Pages

Effect of Human Milk Components on Infant Growth and Body Composition

  • Zoya Gridneva,
  • Isabella Norrish,
  • Azhar Sindi,
  • Vanessa S. Sakalidis,
  • Mya Thway Tint,
  • Sharon L. Perrella,
  • Mark P. Nicol and
  • Donna T. Geddes

Human milk (HM) is an important source of nutrition for infants that provides all elements necessary for their growth and development. Previous studies have reported associations between breastfeeding and a reduced risk of developing obesity and late...

  • Study Protocol
  • Open Access
7 Citations
4,436 Views
10 Pages

Adequate nutrition of very preterm infants comprises fortification of human milk (HM), which helps to improve their nutrition and health. Standard HM fortification involves a fixed dose of a multi-nutrient HM fortifier, regardless of the composition...

  • Article
  • Open Access
36 Citations
6,660 Views
19 Pages

Human Milk Lactose, Insulin, and Glucose Relative to Infant Body Composition during Exclusive Breastfeeding

  • Ali S. Cheema,
  • Lisa F. Stinson,
  • Alethea Rea,
  • Ching Tat Lai,
  • Matthew S. Payne,
  • Kevin Murray,
  • Donna T. Geddes and
  • Zoya Gridneva

22 October 2021

Human milk (HM) components may influence infant growth and development. This study aimed to investigate relationships between infant body composition (BC) and HM lactose, insulin, and glucose (concentrations and calculated daily intakes (CDI)) as wel...

  • Article
  • Open Access
53 Citations
10,215 Views
24 Pages

Human Milk Adiponectin and Leptin and Infant Body Composition over the First 12 Months of Lactation

  • Zoya Gridneva,
  • Sambavi Kugananthan,
  • Alethea Rea,
  • Ching Tat Lai,
  • Leigh C. Ward,
  • Kevin Murray,
  • Peter E. Hartmann and
  • Donna T. Geddes

20 August 2018

Human milk (HM) adipokines may influence infant feeding patterns, appetite regulation, and body composition (BC). The associations between concentrations/calculated daily intakes (CDI) of HM adipokines in the first 12 months postpartum and maternal/t...

  • Article
  • Open Access
62 Citations
9,909 Views
24 Pages

Carbohydrates in Human Milk and Body Composition of Term Infants during the First 12 Months of Lactation

  • Zoya Gridneva,
  • Alethea Rea,
  • Wan Jun Tie,
  • Ching Tat Lai,
  • Sambavi Kugananthan,
  • Leigh C. Ward,
  • Kevin Murray,
  • Peter E. Hartmann and
  • Donna T. Geddes

28 June 2019

Human milk (HM) carbohydrates may affect infant appetite regulation, breastfeeding patterns, and body composition (BC). We investigated relationships between concentrations/calculated daily intakes (CDI) of HM carbohydrates in first year postpartum a...

  • Article
  • Open Access
5 Citations
5,675 Views
15 Pages

Statistical Approaches in the Studies Assessing Associations between Human Milk Immune Composition and Allergic Diseases: A Scoping Review

  • Oleg Blyuss,
  • Ka Yan Cheung,
  • Jessica Chen,
  • Callum Parr,
  • Loukia Petrou,
  • Alina Komarova,
  • Maria Kokina,
  • Polina Luzan,
  • Egor Pasko and
  • Daniel Munblit
  • + 11 authors

10 October 2019

A growing number of studies are focusing on the associations between human milk (HM) immunological composition and allergic diseases. This scoping review aims to identify statistical methods applied in the field and highlight pitfalls and unmet needs...

  • Article
  • Open Access
83 Citations
13,326 Views
16 Pages

Human Milk Composition and Dietary Intakes of Breastfeeding Women of Different Ethnicity from the Manawatu-Wanganui Region of New Zealand

  • Christine A. Butts,
  • Duncan I. Hedderley,
  • Thanuja D. Herath,
  • Gunaranjan Paturi,
  • Sarah Glyn-Jones,
  • Frank Wiens,
  • Bernd Stahl and
  • Pramod Gopal

4 September 2018

Human milk is nutrient rich, complex in its composition, and is key to a baby’s health through its role in nutrition, gastrointestinal tract and immune development. Seventy-eight mothers (19–42 years of age) of Asian, Māori, Pacific Islan...

  • Article
  • Open Access
20 Citations
4,232 Views
15 Pages

24 July 2020

Human milk oligosaccharides (HMOs) are bioactive molecules in human milk that play a critical role in infant health. Obesity and associated metabolic aberrations can negatively impact lactation and alter milk composition. Here, the relationship betwe...

  • Article
  • Open Access
6 Citations
2,984 Views
23 Pages

Investigation of Relationships between Intakes of Human Milk Total Lipids and Metabolic Hormones and Infant Sex and Body Composition

  • Majed A. Suwaydi,
  • Ching Tat Lai,
  • Ashleigh H. Warden,
  • Sharon L. Perrella,
  • Jacki L. McEachran,
  • Mary E. Wlodek,
  • Donna T. Geddes and
  • Zoya Gridneva

16 August 2024

Human milk (HM) composition, including metabolic hormones and lipids, is influenced by various factors, including lactation stage and, potentially, infant sex, which may affect infant body composition (BC) development. We aimed to: (a) characterize t...

  • Article
  • Open Access
40 Citations
18,808 Views
25 Pages

Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation

  • Zoya Gridneva,
  • Wan J. Tie,
  • Alethea Rea,
  • Ching Tat Lai,
  • Leigh C. Ward,
  • Kevin Murray,
  • Peter E. Hartmann and
  • Donna T. Geddes

19 September 2018

Human milk (HM) influences infant feeding patterns and body composition (BC). This small proof-of concept longitudinal study investigated relationships between infant/maternal BC and HM casein, whey and total protein during the first 12 months of lac...

  • Review
  • Open Access
83 Citations
8,788 Views
21 Pages

The Impact of Maternal Obesity on Human Milk Macronutrient Composition: A Systematic Review and Meta-Analysis

  • Gabriela E. Leghi,
  • Merryn J. Netting,
  • Philippa F. Middleton,
  • Mary E. Wlodek,
  • Donna T. Geddes and
  • Beverly S. Muhlhausler

27 March 2020

Maternal obesity has been associated with changes in the macronutrient concentration of human milk (HM), which have the potential to promote weight gain and increase the long-term risk of obesity in the infant. This article aimed to provide a synthes...

  • Article
  • Open Access
11 Citations
3,310 Views
19 Pages

Individualized Fortification Based on Measured Macronutrient Content of Human Milk Improves Growth and Body Composition in Infants Born Less than 33 Weeks: A Mixed-Cohort Study

  • Manuela Cardoso,
  • Daniel Virella,
  • Ana Luísa Papoila,
  • Marta Alves,
  • Israel Macedo,
  • Diana e Silva and
  • Luís Pereira-da-Silva

22 March 2023

The optimal method for human milk (HM) fortification has not yet been determined. This study assessed whether fortification relying on measured HM macronutrient content (Miris AB analyzer, Upsala, Sweden) composition is superior to fortification base...

  • Article
  • Open Access
86 Citations
8,735 Views
18 Pages

Associations between Maternal Body Composition and Appetite Hormones and Macronutrients in Human Milk

  • Sambavi Kugananthan,
  • Zoya Gridneva,
  • Ching T. Lai,
  • Anna R. Hepworth,
  • Peter J. Mark,
  • Foteini Kakulas and
  • Donna T. Geddes

9 March 2017

Human milk (HM) appetite hormones and macronutrients may mediate satiety in breastfed infants. This study investigated associations between maternal adiposity and concentrations of HM leptin, adiponectin, protein and lactose, and whether these concen...

  • Review
  • Open Access
4 Citations
6,700 Views
21 Pages

From Mind to Milk: The Influence of Psychological Factors on the Composition of Human Breast Milk

  • Krystian Skowron,
  • Igor Lichocki,
  • Filip Godziszewski and
  • Magdalena Orczyk-Pawiłowicz

20 March 2025

Background/Objectives: Breast milk is a complex fluid crucial for infant development, nutrition, and immunological and neurodevelopmental support. Recent findings suggest that factors regarding mental health, such as stress, anxiety, and postpartum d...

  • Article
  • Open Access
16 Citations
4,757 Views
21 Pages

Comparison of the Lipid Composition of Milk Fat Globules in Goat (Capra hircus) Milk during Different Lactations and Human Milk

  • Guangqin Liao,
  • Tiancai Wang,
  • Xiabing Li,
  • Jingyi Gu,
  • Qi Jia,
  • Zishuang Wang,
  • Houru Li,
  • Yongzhong Qian and
  • Jing Qiu

23 May 2024

Goat milk is considered the optimal substitute for human milk and is characterized by variations in the lipid composition of its fat globules across lactation phases. Therefore, the objective of this study was to thoroughly analyze the differences be...

  • Article
  • Open Access
22 Citations
8,720 Views
42 Pages

Human Milk Composition and Nutritional Status of Omnivore Human Milk Donors Compared with Vegetarian/Vegan Lactating Mothers

  • Noelia Ureta-Velasco,
  • Kristin Keller,
  • Diana Escuder-Vieco,
  • Javier Fontecha,
  • María V. Calvo,
  • Javier Megino-Tello,
  • José C. E. Serrano,
  • Carmen Romero Ferreiro,
  • Nadia Raquel García-Lara and
  • Carmen R. Pallás-Alonso

12 April 2023

Women of childbearing age in Western societies are increasingly adopting vegetarian diets. These women are sometimes rejected as milk donors, but little about the composition of their milk is known. The present study aimed to compare the intake, nutr...

  • Communication
  • Open Access
58 Citations
7,935 Views
15 Pages

Influence of Diabetes during Pregnancy on Human Milk Composition

  • Chiara Peila,
  • Diego Gazzolo,
  • Enrico Bertino,
  • Francesco Cresi and
  • Alessandra Coscia

9 January 2020

Human milk (HM) is a unique nourishment believed to contain biological factors contributing to both short and long-term benefits. Considering that a mother’s own milk is often considered the first choice for nutrition of neonates, an aspect of...

  • Article
  • Open Access
47 Citations
6,991 Views
17 Pages

Variation in Human Milk Composition Is Related to Differences in Milk and Infant Fecal Microbial Communities

  • Ryan M. Pace,
  • Janet E. Williams,
  • Bianca Robertson,
  • Kimberly A. Lackey,
  • Courtney L. Meehan,
  • William J. Price,
  • James A. Foster,
  • Daniel W. Sellen,
  • Elizabeth W. Kamau-Mbuthia and
  • Michelle K. McGuire
  • + 12 authors

Previously published data from our group and others demonstrate that human milk oligosaccharide (HMOs), as well as milk and infant fecal microbial profiles, vary by geography. However, little is known about the geographical variation of other milk-bo...

  • Article
  • Open Access
1 Citations
3,320 Views
20 Pages

Composition and Antioxidant Status of Human Milk of Women Living in Bydgoszcz (Poland)

  • Agnieszka Dombrowska-Pali,
  • Agnieszka Chrustek,
  • Dorota Olszewska-Słonina and
  • Maciej W. Socha

6 October 2024

Objectives: The aim of this study was to compare cortisol concentrations, nutritional composition, and the antioxidant status of human milk of women living in Bydgoszcz (Poland), taking into account maternal factors (fertility, area of residence, eco...

  • Review
  • Open Access
137 Citations
18,239 Views
16 Pages

Circadian Variation in Human Milk Composition, a Systematic Review

  • Merel F. Italianer,
  • Eva F. G. Naninck,
  • Jorine A. Roelants,
  • Gijsbertus T. J. van der Horst,
  • Irwin K. M. Reiss,
  • Johannes B. van Goudoever,
  • Koen F. M. Joosten,
  • Inês Chaves and
  • Marijn J. Vermeulen

4 August 2020

Background: Breastfeeding is considered the most optimal mode of feeding for neonates and mothers. Human milk changes over the course of lactation in order to perfectly suit the infant’s nutritional and immunological needs. Its composition also...

  • Article
  • Open Access
63 Citations
6,250 Views
12 Pages

Impact of Maternal Diet on Human Milk Composition Among Lactating Women in Latvia

  • Līva Aumeistere,
  • Inga Ciproviča,
  • Dace Zavadska,
  • Juris Andersons,
  • Viktors Volkovs and
  • Kristīne Ceļmalniece

Background and objectives: Many studies indicate that the maternal diet is an important factor affecting human milk composition. Human milk composition among lactating women in Latvia, as well as the maternal diet during lactation, has not been suffi...

  • Article
  • Open Access
33 Citations
10,987 Views
10 Pages

Variation in the Protein Composition of Human Milk during Extended Lactation: A Narrative Review

  • Sergio Verd,
  • Gemma Ginovart,
  • Javier Calvo,
  • Jaume Ponce-Taylor and
  • Antoni Gaya

20 August 2018

The aim of this review is to evaluate changes in protein parameters in the second year postpartum. There is considerable agreement among authors about the declining trend of human milk protein concentrations, but most research on protein content in b...

  • Article
  • Open Access
23 Citations
7,819 Views
12 Pages

4 December 2019

There is growing evidence that omega-3 (n-3) polyunsaturated fatty-acids (PUFAs) are important for the brain development in childhood and are necessary for an optimal health in adults. However, there have been no studies examining how the n-3 PUFA co...

  • Review
  • Open Access
9 Citations
3,203 Views
16 Pages

Modifiable and Non-Modifiable Factors That Affect Human Milk Oligosaccharides Composition

  • Małgorzata Konieczna,
  • Anna Koryszewska-Bagińska,
  • Agnieszka Bzikowska-Jura,
  • Magdalena Chmielewska-Jeznach,
  • Sylwia Jarzynka and
  • Gabriela Olędzka

28 August 2024

Human milk, the gold standard in infant nutrition, is a unique fluid that provides essential nutrients such as lactose, lipids, proteins, and free oligosaccharides. While its primary role is nutritional, it also protects against pathogens. This prote...

  • Article
  • Open Access
56 Citations
7,546 Views
14 Pages

Quantification of Human Milk Phospholipids: the Effect of Gestational and Lactational Age on Phospholipid Composition

  • Ida Emilie Ingvordsen Lindahl,
  • Virginia M. Artegoitia,
  • Eimear Downey,
  • James A. O’Mahony,
  • Carol-Anne O’Shea,
  • C. Anthony Ryan,
  • Alan L. Kelly,
  • Hanne C. Bertram and
  • Ulrik K. Sundekilde

22 January 2019

Human milk (HM) provides infants with macro- and micronutrients needed for growth and development. Milk phospholipids are important sources of bioactive components, such as long-chain polyunsaturated fatty acids (LC-PUFA) and choline, crucial for neu...

  • Review
  • Open Access
3 Citations
4,241 Views
29 Pages

27 February 2025

Milk is the principal nutrient of newborn humans and a diagnostic feature of the order Mammalia. Its release is elicited as a reflex by infant sucking under the control of the hormone oxytocin. While it is recognized that breast milk optimally promot...

  • Communication
  • Open Access
3 Citations
3,222 Views
7 Pages

Human Milk Fatty Acid Composition of Allergic and Non-Allergic Mothers: The Ulm SPATZ Health Study

  • Linda P. Siziba,
  • Leonie Lorenz,
  • Bernd Stahl,
  • Marko Mank,
  • Tamas Marosvölgyi,
  • Tamas Decsi,
  • Dietrich Rothenbacher and
  • Jon Genuneit

10 June 2020

The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data....

  • Review
  • Open Access
102 Citations
76,630 Views
11 Pages

Sex-Specific Human Milk Composition: The Role of Infant Sex in Determining Early Life Nutrition

  • Laura Galante,
  • Amber M. Milan,
  • Clare M. Reynolds,
  • David Cameron-Smith,
  • Mark H. Vickers and
  • Shikha Pundir

1 September 2018

Male and female infants respond differentially to environmental stimuli, with different growth and neurodevelopmental trajectories. Male infants are more likely to be disadvantaged when subjected to adversity and show a higher risk of perinatal compl...

  • Article
  • Open Access
11 Citations
3,993 Views
12 Pages

This study investigated the influence of selected maternal factors on the macronutrient composition and energy of human milk (HM). The study enrolled 159 breastfeeding mothers from five postpartum care centers in Seoul, Korea. Their gestational weeks...

  • Article
  • Open Access
11 Citations
3,147 Views
10 Pages

Human Milk Fatty Acid Composition and Its Effect on Preterm Infants’ Growth Velocity

  • Batool Ahmed,
  • Afnan Freije,
  • Amina Omran,
  • Mariangela Rondanelli,
  • Mirko Marino and
  • Simone Perna

This study aimed to analyze the fatty acid content in human milk and to find its relationship with the growth velocity of preterm infants. Mature milk samples from 15 mothers of preterm infants were collected from three different hospitals, followed...

  • Article
  • Open Access
48 Citations
8,707 Views
13 Pages

Dietary Patterns of Breastfeeding Mothers and Human Milk Composition: Data from the Italian MEDIDIET Study

  • Francesca Bravi,
  • Matteo Di Maso,
  • Simone R. B. M. Eussen,
  • Carlo Agostoni,
  • Guglielmo Salvatori,
  • Claudio Profeti,
  • Paola Tonetto,
  • Pasqua Anna Quitadamo,
  • Iwona Kazmierska and
  • on behalf of the MEDIDIET Working Group
  • + 6 authors

19 May 2021

(1) Background: Several studies have reported associations between maternal diet in terms of single foods or nutrients and human milk compounds, while the overall role of maternal diet and related dietary patterns has rarely been investigated. (2) Me...

  • Article
  • Open Access
14 Citations
4,610 Views
15 Pages

Variations in the Composition of Human Milk Oligosaccharides Correlates with Effects on Both the Intestinal Epithelial Barrier and Host Inflammation: A Pilot Study

  • Richard Y. Wu,
  • Steven R. Botts,
  • Kathene C. Johnson-Henry,
  • Eva Landberg,
  • Thomas R. Abrahamsson and
  • Philip M. Sherman

28 February 2022

Background: Human milk oligosaccharides are complex, non-digestible carbohydrates that directly interact with intestinal epithelial cells to alter barrier function and host inflammation. Oligosaccharide composition varies widely between individual mo...

  • Article
  • Open Access
62 Citations
7,056 Views
12 Pages

Longitudinal Analysis of Macronutrient Composition in Preterm and Term Human Milk: A Prospective Cohort Study

  • Céline J. Fischer Fumeaux,
  • Clara L. Garcia-Rodenas,
  • Carlos A. De Castro,
  • Marie-Claude Courtet-Compondu,
  • Sagar K. Thakkar,
  • Lydie Beauport,
  • Jean-François Tolsa and
  • Michael Affolter

4 July 2019

Background: Mother’s own milk is the optimal source of nutrients and provides numerous health advantages for mothers and infants. As they have supplementary nutritional needs, very preterm infants may require fortification of human milk (HM). A...

  • Article
  • Open Access
23 Citations
4,701 Views
19 Pages

Milk oligosaccharides (OS) shape microbiome structure and function, but their relative abundances differ between species. Herein, the impact of the human milk oligosaccharides (HMO) (2′-fucosyllactose [2′FL] and lacto-N-neotetraose [LNnT]) and OS iso...

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