Search Results (13,121)

Objectives: Concentrated pills, as a modernization and upgrade of traditional pills, have achieved significant advancements in dosage form. However, their extended disintegration and dispersion times have become a major limitation to their therapeutic efficacy. Therefore, an in-depth study and explanation of the dissolution mechanism of concentrated pills, along with the development of processing technology to control dissolution time, has emerged as a critical bottleneck in improving the quality of concentrated pills. Methods: In this study, the Liuwei Dihuang (LWDH) concentrated pill, derived from the classical Liuwei Dihuang pill, was selected as a representative model. Two drying methods—hot-air drying and hot air–microwave combined drying—were comparatively investigated to evaluate their effects on dissolution time. The dissolution behavior was elucidated by analyzing water migration during the dissolution process, as well as the textural properties and internal structural characteristics of the pills using Low-Field Nuclear Magnetic Resonance (LF-NMR), Micro-Computed Tomography (Micro-CT), texture analysis, and other modern techniques. Results: The results indicated that: (i) The rate of water absorption during the dissolution process of the LWDH pill was influenced by the number and size of the internal pores. (ii) Hot air–microwave combined drying results in more pores and faster dissolution. (iii) High-Performance Liquid Chromatography (HPLC) fingerprints showed no significant differences in the active ingredients between the samples. Conclusions: The drying method significantly affected the internal structure of the pills, suggesting that controlling the drying process could address the prolonged dissolution time of concentrated pills. Full article

This study investigates the enhancement of hydrogen production efficiency in water electrolysis through the application of external magnetic fields. A series of controlled experiments were conducted using four distinct electrode materials—stainless steel (SS), low-carbon steel (LCS), titanium (Ti), and platinum-plated titanium (Ti/Pt)—to identify the optimal configuration for maximizing gas output. The research evaluated the influence of electrolyte concentration (KOH), current density, and magnetic field intensity ranging from 0 to 1800 G. Our findings indicate that the application of a 200 G magnetic field leads to a notable 6% increase in the rate of gas production compared to non-magnetized conditions. Specifically, a magnetic field oriented parallel to the electrode plates outperformed a perpendicular orientation by approximately 5%, a phenomenon attributed to the Lorentz force facilitating ionic mass transfer and gas bubble detachment. Furthermore, the integration of ion-exchange and proton-exchange membranes (MC-3470 and N-117) effectively isolated the anodic and cathodic products, elevating hydrogen purity from 67.4% to approaching 100% without compromising electrolysis efficiency. These results demonstrate that the strategic coupling of moderate magnetic fields with optimized electrode configurations provides a promising pathway for improving the efficiency and cleanliness of hydrogen production, which is essential for its role as a sustainable energy carrier. Full article

Background and aims. Liver mechanical properties’ (stiffness/viscoelasticity) evaluation is relevant for diagnosing/monitoring liver fibrosis. Due to limitations of the commonly used elastography, we propose the use of rheology and Low Field-Nuclear Magnetic Resonance (LF-NMR). Methods. In 30 liver samples from patients undergoing bariatric surgery and 18 control samples, we evaluated the shear modulus G/critical stress τc (elastic properties) and mean complex modulus $G_{\mathrm{a}}^{*}$ (elastic/viscous properties) by rheology. LF-NMR was used to measure the spin–spin relaxation time (T_2m), reflecting iron content. The expression of iron-related proteins and of pro-fibrotic proteins were evaluated by qRT-PCR. Tissue histology was also determined. Results. $G_{\mathrm{a}}^{*}$/G/τ_c were higher in pathological samples, which also showed increased expression of pro-fibrotic proteins. Fibrosis determination displayed a correspondence of 4/30 samples for elastography/histology and 17/30 for rheology/histology. T_2m was significantly lower in pathological livers, indicating iron accumulation as confirmed by increased expression of iron-related proteins. T_2m was more effective than histology in detecting iron. An inverse correlation was observed between T_2m and $G_{\mathrm{a}}^{*}$/G showing that iron accumulation is associated with increased liver elasticity/viscoelasticity, i.e., fibrosis. Additionally, an inverse correlation of $G_{\mathrm{a}}^{*}$/G with transferrin, was observed. Conclusion. As our patients mostly have mild liver fibrosis, the combined use of rheology/LF-NMR can effectively detect early changes in liver mechanical properties, aiding in staging and diagnosis of fibrosis. Full article

The purpose of this research is to determine which factors contribute to extending the read range of transponders equipped with different coupling-circuit topologies operating within selected RFID frequency bands. The analysis covered transponders that varied in both the configuration of their coupling circuits and their geometric dimensions. To accomplish this, transponder models were created using the EMCoS Studio electromagnetic simulation environment. Each model was subjected to simulations that yielded the mutual inductance and the voltage induced at the chip terminals. This study examines how the impedance of the embroidered antenna, the impedance of the chip’s coupling circuit, and the magnetic flux density affect the resulting chip voltage. In several of the investigated configurations, the peak chip voltage appeared outside the frequency range normally associated with RFID systems. The frequency at which this maximum occurred was dependent on the mutual inductance value. Understanding how individual parameters influence mutual inductance makes it possible to shift the voltage peak into a target operating band. Numerical simulation results, combined with the transponder’s mathematical model, enabled the calculation of the mutual inductance and the terminal voltage—quantities that directly determine the achievable read range. This study focuses on factors such as the resonant frequencies of the antenna and coupling circuit, their impedances, and the characteristics of the magnetic field. The findings show that tuning these parameters can affect not only the location of the voltage maximum, but also its amplitude. This effect introduces additional complexity in designing and selecting suitable transponder configurations. Full article

Strong magnetic fields and anisotropic stresses can substantially modify the structure and observable properties of compact stars. In this review, we present a unified treatment of magnetically induced anisotropy across neutron stars, hybrid stars, and white dwarfs, connecting the microphysical equation of state effects to macroscopic structure and multimessenger observables. We demonstrate that magnetic-field geometry plays a decisive role: toroidally oriented (transverse) fields enhance the maximum mass by providing additional perpendicular pressure support, whereas radially oriented fields primarily increase central compression with comparatively small mass gain. In neutron stars, anisotropy and magnetic stresses can shift phase-transition thresholds in hybrid models and enable configurations in the lower mass gap with significantly smaller magnetic energy compared to the gravitational binding energy. We further show that continuous gravitational wave emission from magnetically deformed neutron stars provides a complementary probe of internal field geometry through ellipticity-driven strain evolution. In magnetized white dwarfs, super-Chandrasekhar masses arise from the spatial redistribution of magnetic stresses rather than from globally strong magnetic energy. Taken together, these results highlight that magnetic-field geometry and matter anisotropy are as important as field strength in determining mass–radius relations, tidal deformability, gravitational wave detectability, and the emergence of extreme compact-star configurations. Full article

Anti-collision detection technologies primarily rely on optical, radar, or laser sensors; however, their performance often deteriorates severely under adverse weather conditions (e.g., rain, snow, fog) or in scenarios involving visual occlusion. By contrast, magnetic anomaly detection leverages perturbations in the geomagnetic field induced by target objects (e.g., vehicles, metallic obstacles), exhibiting intrinsic all-weather operability and strong anti-interference capability. Nevertheless, conventional magnetic anomaly detection methods suffer from the limited applicability of the magnetic dipole model, which only affords coarse positioning accuracy and is predominantly suited for long-range targets. To address this limitation, this paper proposes an Extended N-th-Pole Magnetic Dipole (E-NMD) model that improves accuracy by analyzing the Lagrangian cosine term and rigorously constraining truncation errors under specific operational conditions. Experimental results demonstrate that, for steel with a relative permeability of 200, the model achieves a fitting variance of 99.87%. Furthermore, to overcome the inversion difficulties arising when the strength of short-range magnetic anomalies is comparable to sensor noise, an Adaptive Iterative Extended Kalman Filter (AI-EKF) is developed to enable robust noise suppression and precise distance estimation. Results indicate that E-NMD outperforms the traditional N-th-Pole Magnetic Dipole (NMD) model in proximal state estimation, achieving a 39.62% reduction in Root Mean Square Error (RMSE). Finally, in light of parameter uncertainty in magnetic anomaly targets under real-world conditions, a Dual-Mode Pairwise Iterative Extended Kalman Filter (DI-EKF) is introduced to jointly estimate parameters and system states, yielding an 89% reduction in RMSE compared to AI-EKF. Full article

To address the issue of insufficient output voltage of the self-powered unit of intelligent bearings under low-amplitude working conditions, a piezoelectric–friction composite energy harvester driven by rotating magnetic force is proposed based on the multi-physical field coupling and synergy of magnetoelectric, piezoelectric and triboelectric effects, which effectively enhances the voltage output in low-amplitude vibration environments. The intelligent bearing adopts an extended structure, consisting of an outer ring sleeve, an inner ring extension ring, magnetic poles and a composite energy harvester. The outer ring sleeve is nested on the outer ring of the bearing and fixes the composite energy harvester, while the inner ring extension ring is fixed on the inner ring of the bearing and installs the magnetic poles. The composite energy harvester adopts a magnetic double-mass block single-crystal piezoelectric simply supported beam structure and integrates a contact-separation type triboelectric nanogenerator in the vibration direction, achieving the collaborative power supply of the piezoelectric and triboelectric units. A mechanical-electrical coupling dynamic model of the composite energy harvester is developed. Using COMSOL software, the effects of various structural dimensions and magnetic pole configurations on the output voltage are analyzed. Experimental validation confirms the model’s effectiveness. The results demonstrate that the energy harvester operates effectively under varying bearing rotational speeds. The rotational speed of the magnetic poles has little influence on the output voltage amplitude but primarily affects its frequency. Under the condition that the rotational speed is within 600 r/min, the piezoelectric module stably outputs a peak voltage of approximately 16.6 V, and the triboelectric unit stably outputs a peak voltage of approximately 4.4 V, which can effectively meet the self-driving requirements of intelligent bearings. Full article

Transmission electron microscopy (TEM) is an essential technique for characterizing nanomaterials. However, specimen preparation, which is a critical factor affecting image quality, remains a practical challenge. Focusing on nanopowders used in materials and chemical science, this article employs case studies to analyze the key steps in TEM specimen preparation. Carbon support films (CSFs) are essential tools for specimen preparation, and this study introduces several commonly used, cost-effective options, including conventional CSFs, conventional holey CSFs, ultrathin holey CSFs, and double-grid support films. We characterize their structural and morphological characteristics and evaluate their suitability for different types of samples. Several representative case studies of nanopowders, spanning from zero-dimensional (0D) to one-dimensional (1D) and two-dimensional (2D) materials, are used to illustrate tailored specimen preparation approaches, which serve as practical references for researchers conducting TEM characterization. These findings facilitate higher image reliability and experimental efficiency, thereby providing critical support for advancing fundamental exploration and frontier innovation in nanomaterial science. Full article

This study investigates the effect of complex nanomodification combined with the simultaneous application of magnetic fields and mechanical vibration on the structure formation and performance properties of medium-alloy steel 40CrNi3MoV. Improving the structural homogeneity and operational characteristics of such steels remains an important task due to their widespread use in components operating under severe loading and wear conditions. The introduction of the nanostructured modifier InSteel-7 at a concentration of 0.03%, together with simultaneous magnetic and vibrational treatment of the melt, resulted in pronounced structural homogenization and grain refinement. Quantitative metallographic analysis using Thixomet Pro image analyzer revealed a significant refinement of the dendritic structure, with the secondary dendrite arm spacing decreasing from 73.9 μm to 27.9 μm. X-ray phase analysis confirmed the preservation of phase composition while indicating increased structural uniformity of the BCC matrix. Energy-dispersive spectroscopy and elemental micro-mapping demonstrated high chemical purity of the alloy and a uniform distribution of the modifier components. The combined treatment significantly improved the mechanical and tribological characteristics of the material. The average hardness increased from 390 HV to 510 HV, while tribological tests showed a reduction in wear track depth from 5.16 μm to 0.87 μm and a decrease in surface roughness from Ra 2.13 μm to 0.20 μm, indicating enhanced wear resistance. Full article

We suggest Josephson interferometry as a quantitative probe of spin–orbit-driven phenomena in superconducting heterostructures. Two distinct mechanisms are analyzed: (i) intrinsic helical superconductivity, producing asymmetric Fraunhofer patterns with lobe deformations and field-reversal asymmetry, and (ii) emergent interfacial magnetism in ferromagnet–superconductor hybrids, where Rashba spin–orbit coupling generates spontaneous fields that rigidly shift the interference fringes. The predicted signatures—flux-shifted interference minima, anisotropic critical current suppression, and angle-dependent pattern distortions—provide direct experimental access to finite-momentum pairing and interface-localized fields via standard Josephson current measurements. Full article

This paper presents the results of numerical calculation of steady-state magnetorheological fluid flow in the gap of an eccentric seal subjected to an external radial magnetic field. A coupled problem combining magnetic field analysis and laminar viscoplastic flow with Bingham rheology is solved to obtain pressure and velocity distributions within the seal gap, from which the hydrodynamic reaction forces of the fluid film and the rotor friction torque are determined. A parametric study was conducted in the ranges of rotor angular velocity ω = 100–400 rad/s, relative eccentricity ε = 0–0.9, and magnetic flux density B₀ = 0–0.5 T at the pressure differential Δp = 2 atm. Analysis of the results shows that increasing the magnetic flux density from 0 to 0.5 T leads to an increase in the seal reaction force from 12 N to 642 N and the friction torque from 0.35 N·m to 11.23 N·m. The most intensive growth of both characteristics is observed in the range B₀ = 0–0.3 T, beyond which saturation occurs as the MRF yield stress reaches its plateau value. An optimal control range of B₀ = 0.1–0.2 T was determined, ensuring maximum seal energetic efficiency as quantified by the load capacity-to-friction torque ratio, which is maximized at 70 N/(N·m). Based on the obtained results, the consequences of using magnetorheological seals on the performance of the rotor system are discussed, including the analysis of the sealing effect on rotor-dynamic stability. Within the proposed optimal range, it is shown that an increase in magnetic flux density leads to a sign reversal of the horizontal reaction F₂, while the monotonic growth of the ratio |F₂|/F₁ indicates an intensification of cross-coupling and a corresponding reduction in the rotordynamic stability margin at higher values of B₀. Full article

Superhydrophobic fiber films, as a typical superhydrophobic material, have advantages such as self-cleaning, non-wettability, and pollution resistance. They can be widely used in oil-water separation, antibacterial, anti-pollution, anti-icing, and self-cleaning fields. Traditional electrospun superhydrophobic fiber films face difficulties in fabricating fibers with large contact angles due to the non-Newtonian fluid flow and Taylor cone jet trajectory limitations. To address this challenge, this study develops a novel ultrasonic-magnetic field coupling electrospinning strategy for fabricating poly(methyl methacrylate)-polystyrene (PMMA-PS) fibrous films with enhanced superhydrophobicity. Physical, chemical, and contact angle measurements were used to analyze the morphology, composition, and hydrophobic properties of the fabricated films. The results showed that by controlling the blend ratio of PMMA and PS and optimizing the electrospinning process with ultrasonic vibration and magnetic field coupling, PMMA-PS fibers with better fiber refinement, closer spindle-shaped arrangements, and significantly increased roughness were successfully fabricated. When using 15% PMMA and 15% PS solutions, the static contact angle of the resulting fiber films reached 173.1°, demonstrating the best superhydrophobicity. The study suggests that optimizing the surface morphology of the nanofibers is an effective method to improve hydrophobicity and provides a new approach for fabricating superhydrophobic fiber films. Full article

Background/Objectives: Most brain magnetic resonance imaging (MRI) is performed in supine position, although posture may influence cerebrovascular signal characteristics through gravity-related physiological changes. However, posture-dependent vascular signal alterations on low-field MRI have not been sufficiently quantified. This study aimed to quantify posture-related internal carotid artery (ICA) signal alterations using low-field MRI by comparing seated and supine images with intensity-, noise-, and texture-based metrics. Methods: Nine healthy adults (20–69 years old; one female) underwent 0.25 T tilting MRI in supine and seated postures. 3D gradient echo T1-weighted images were obtained. The bilateral ICA regions of interest (ROI) and adjacent reference ROI were manually delineated. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), signal intensity ratio (SIR), gray-level co-occurrence matrix (GLCM) texture features (contrast, correlation, energy, and homogeneity) were extracted and compared between postures using Wilcoxon signed-rank tests. Results: Seated posture produced significantly higher ICA signal intensity metrics than the supine posture, with increased SNR (median 17.11 vs. 13.48), CNR (median 21.94 vs. 18.36), and SIR (median 10.84 vs. 9.54) (p = 0.004). GLCM texture analysis demonstrated a significant decrease in contrast in the seated position (median 62.01 vs. 145.92; p = 0.004), whereas correlation, energy, and homogeneity showed no significant between-posture differences. Conclusions: Low-field MRI was sensitive to posture-dependent ICA signal alterations. ICA-based metrics may provide quantitative markers of gravity-related cerebrovascular adaptation. Full article

Objective: To report on a series of three cases in which problems with rotating magnets (blocked rotation, demagnetization) occurred in cochlear implants and to resolve these problems without surgical intervention. Methods: Of the 3635 devices with rotating magnets implanted at this tertiary referral hospital, 2 exhibited rotation blockage (associated with misalignment of the coil or audio processor), and 1 was partially demagnetized in a 1.5 T MRI scanner. Results: One blockage resolved spontaneously without intervention. The second blockage was resolved in the static field of a 3T MRI scanner, where the demagnetized magnet was also re-magnetized to its original strength. Surgical intervention or re-implantation was not necessary in either case. Conclusions: Surgical intervention or re-implantation is not primarily required in the event of problems with the rotating implant magnet. Prior to surgery, technical analysis can lead to a conservative solution. Full article

Magnetoplasmadynamic thrusters represent a promising Electric Propulsion technology for future space missions; however, their optimization is hampered by the lack of accurate performance models in the emerging regime of low power (<12 kW) and high magnetic fields (>0.1 T), where traditional formulations prove inadequate. In this work, a new semi-empirical model for predicting the thrust and discharge voltage of argon-fed MPD thrusters was developed and validated. Starting from state-of-the-art physical models, multi-factorial correction factors were introduced to account for the coupled effects of discharge current (8–180 A), mass flow rate (3–21 mg/s), and applied magnetic field (up to 0.6 T). The model was calibrated and validated using a comprehensive and homogeneous collection of experimental data from the literature. A comparative analysis demonstrates that the corrected model significantly reduces prediction errors (0–9%) compared to reference models available in the literature (8–50%). In particular, the model exhibits remarkably superior accuracy in both the Self-Field and Applied-Field regimes, overcoming the main limitations of previous formulations and providing more robust estimates across a wide operational envelope. The developed model constitutes a reliable and physically consistent tool for the analysis and preliminary design of low-power, argon-fed magnetoplasmadynamic thrusters, enabling more effective optimization for this class of propulsion systems. Full article