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Keywords = metallocatalysis

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13 pages, 1874 KB  
Article
Possible Role of Vesicles on Metallocatalytic Reduction Reaction of 5-Hydroxymethylfurfural to 2,5-Dimethylfuran
by Toshinori Shimanouchi, Yuki Takahashi, Keita Hayashi, Kazuma Yasuhara and Yukitaka Kimura
Compounds 2022, 2(4), 321-333; https://doi.org/10.3390/compounds2040027 - 3 Nov 2022
Cited by 4 | Viewed by 2196
Abstract
A reduction reaction of 5-hydroxymethylfurfural to 2,5-dimethylfuran (2,5-DMF) has been previously performed in an organic solvent under high-temperature conditions. For the relaxation of such reaction conditions, conventional palladium on carbon (Pd/C) was combined with vesicles composed of phospholipids or surfactants. Pd/C combined with [...] Read more.
A reduction reaction of 5-hydroxymethylfurfural to 2,5-dimethylfuran (2,5-DMF) has been previously performed in an organic solvent under high-temperature conditions. For the relaxation of such reaction conditions, conventional palladium on carbon (Pd/C) was combined with vesicles composed of phospholipids or surfactants. Pd/C combined with 1,2-dioleoyl-sn-glycero-3-phosphocholine indicated a yield (25%) at 60 °C compared with Pd/C (17%). Vesicles at the liquid crystalline phase were advantageous for the reduction reaction of HMF. The yield of 2,5-DMF catalyzed by Pd/C combined with the vesicles depended on the lipid composition of the vesicles. It was clarified that the yield of 2,5-DMF could be controlled by the hydration property of the vesicles. Compared with conventional 2,5-DMF synthesis in an organic solvent, the use of vesicles made it possible to reduce the burden of using organic solvents in high-temperature conditions, although limitedly. Full article
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35 pages, 9699 KB  
Review
Organocatalysis and Beyond: Activating Reactions with Two Catalytic Species
by Arianna Sinibaldi, Valeria Nori, Andrea Baschieri, Francesco Fini, Antonio Arcadi and Armando Carlone
Catalysts 2019, 9(11), 928; https://doi.org/10.3390/catal9110928 - 6 Nov 2019
Cited by 37 | Viewed by 9781
Abstract
Since the beginning of the millennium, organocatalysis has been gaining a predominant role in asymmetric synthesis and it is, nowadays, a foundation of catalysis. Synergistic catalysis, combining two or more different catalytic cycles acting in concert, exploits the vast knowledge acquired in organocatalysis [...] Read more.
Since the beginning of the millennium, organocatalysis has been gaining a predominant role in asymmetric synthesis and it is, nowadays, a foundation of catalysis. Synergistic catalysis, combining two or more different catalytic cycles acting in concert, exploits the vast knowledge acquired in organocatalysis and other fields to perform reactions that would be otherwise impossible. Merging organocatalysis with photo-, metallo- and organocatalysis itself, researchers have ingeniously devised a range of activations. This feature review, focusing on selected synergistic catalytic approaches, aims to provide a flavor of the creativity and innovation in the area, showing ground-breaking examples of organocatalysts, such as proline derivatives, hydrogen bond-mediated, Cinchona alkaloids or phosphoric acids catalysts, which work cooperatively with different catalytic partners. Full article
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17 pages, 4022 KB  
Article
Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
by Mohamed Zaki, Mohamed Akssira and Sabine Berteina-Raboin
Molecules 2017, 22(4), 652; https://doi.org/10.3390/molecules22040652 - 20 Apr 2017
Cited by 1 | Viewed by 5635
Abstract
The Mizoroki-Heck reaction was applied to substrates derived from isocostic and ilicic acids, important sesquiterpene components of Dittrichia viscosa L. Greuter that were extracted directly from plant material collected in Morocco. After optimization of the metallo-catalysis conditions, various aryl-groups were successfully introduced on [...] Read more.
The Mizoroki-Heck reaction was applied to substrates derived from isocostic and ilicic acids, important sesquiterpene components of Dittrichia viscosa L. Greuter that were extracted directly from plant material collected in Morocco. After optimization of the metallo-catalysis conditions, various aryl-groups were successfully introduced on the exocyclic double bond with an exclusive E-configuration and without racemization. Full article
(This article belongs to the Collection Bioactive Compounds)
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