Search Results (1,117)

Demand for camel milk products is growing in Morocco and worldwide, creating opportunities to strengthen the livelihoods of populations living in arid regions through the development of camel-based dairy value chains. In addition to their economic potential, such value chains may contribute to sustainability by supporting food systems adapted to arid environments, promoting the use of locally resilient livestock species, and enhancing the socio-economic viability of vulnerable rural communities. This exploratory qualitative study investigates urban consumer behavior related to dairy consumption with a specific focus on the potential integration of camel milk products into local dietary habits. To capture nuanced consumer perspectives, gender-segregated focus-group discussions were conducted in three Moroccan cities using a semi-structured questionnaire on dairy consumption habits. Key factors examined included milk types, product preferences, purchasing locations, consumption frequency and willingness to include camel products in the household diet. The results indicate that camel milk is rarely consumed outside areas where camels are raised. Nevertheless, participants expressed interest in several camel milk-based products, particularly fermented milk and spreadable cheeses. This interest was primarily driven by perceptions of camel milk as a healthy product and by its association with traditional food practices. These findings suggest that expanding camel milk consumption in urban markets could support more sustainable and territorially rooted dairy systems by linking consumer demand with production models suited to dryland conditions. This study indicates promising market opportunities for the development of camel milk products in urban areas, particularly if challenges related to pricing strategies, distribution network, and region-specific supply chains are strategically managed. Full article

Short food supply chains (SFSCs) for artisan dairy products promote rural development, cultural preservation, and consumer trust but face challenges not found in mainstream chains. This study focuses on queso Tenate, a traditional cow-milk cheese from central Mexico, and examines how its SFSC organisational structure influences its capacity to ensure food safety, quality consistency, market delivery, and viability. Using a single-case exploratory design, the study applies the Viable System Model (VSM) as a diagnostic framework to map systemic functions within an artisan dairy enterprise. Data were collected through VSM-informed interviews and observations of production and retail practices. The findings show that food safety, quality performance, and market delivery reliability are structurally mediated by systemic coherence, not product characteristics alone. While strong relational coordination and shared identity sustain viability, several functions—particularly coordination, audit, and intelligence—remain person-dependent. This study identifies structural implications for strengthening regulatory coordination and monitoring practices without undermining relational management or artisan identity. The primary contributions are as follows: (i) extending SFSC research through a systemic diagnosis of an artisan dairy chain in an emerging economy; (ii) linking VSM-based organisational study to food safety, quality consistency, and market performance; and (iii) positioning VSM as a conversational tool for SFSC viability. Limitations include the single-case design, reliance on qualitative data, and absence of longitudinal measurements. Future research should compare VSM applications across multiple SFSCs, integrate quantitative analyses, and explore its use as a management tool. The study highlights the role of systemic coherence in ensuring SFSC sustainability and cultural embeddedness. Full article

This study investigates the genetic diversity, population structure, and adaptive differentiation of Yunnan native cattle (YNC) using whole-genome SNP data from 457 individuals, representing eight cattle populations and two closely related bovine species (Zhongdian yak and Dulong gayal). Genetic diversity analyses revealed a distinct latitudinal gradient from north to south, with the highest diversity observed in the northern Diqing (DQC) and Zhaotong (ZTC) populations. The observed population structure was largely consistent with geographic distribution, identifying distinct ancestral components and complex admixture patterns. Genome-wide selective sweep scans revealed several key candidate genes underlying local adaptation. Notably, GRIA4 and DUOXA2 were associated with cold tolerance in northern populations, and ST3GAL3 and MST1 were implicated in heat stress adaptation in southern populations. Genome-wide balancing selection analyses further detected significant loci, such as MGST1 and SLC36A1, where divergent haplotype frequencies reflected differential selective pressures on milk-related traits between northern and southern populations. Additionally, we detected signals of historical introgression from Zhongdian yak into DQC cattle, highlighting the introgressed gene SLIT3 as a potential candidate associated with high-altitude thermogenesis. Collectively, these results provide a comprehensive genomic framework for the management and conservation of indigenous bovine genetic resources in Southwest China. Full article

Background/Objectives: Sustainable food habits are essential for reducing the environmental impacts of a food system. We investigated food sustainability knowledge, attitudes, and food waste-related behaviours among Saudi adults and assessed their associations with socio-demographic characteristics and dietary choices, which are subjects that remain under-researched. Methods: A cross-sectional study was conducted among 855 Saudi adults (≥18 years) using convenience sampling. Data were collected using a validated online questionnaire assessing sustainability knowledge, attitudes, food waste behaviours, dietary choices, and socio-demographic characteristics. Descriptive statistics, chi-square tests, and linear regression analyses were performed using SPSS version 29. Results: Overall, 32% of the study population demonstrated adequate sustainability knowledge, 61% expressed positive attitudes towards food sustainability, and 45% demonstrated favourable food waste management. Women were more knowledgeable than men. Participants who possessed a better understanding of food sustainability consumed more vegetables, fruits, and bread and less processed meat. Those with a positive attitude towards food sustainability exhibited higher consumption of red meat, white meat, eggs, milk, yogurt, cheese, vegetables, fruits, bread, and sweet or savoury snacks. Meanwhile, individuals with better food waste behaviours demonstrated significantly lower consumption of legumes, fish, pasta, red meat, white meat, processed meat, eggs, milk, yogurt, cheese, fruits, bread, and sweet or savoury snacks. Conclusions: Saudi adults possess limited knowledge of sustainability and suboptimal food waste behaviours despite having relatively positive attitudes. These findings highlight opportunities for intervention. Public education, targeted campaigns, and media communication could enhance sustainability awareness and promote healthier, environmentally sustainable dietary patterns. Full article

Background/Objectives: Dietary treatment may play a complimentary part alongside established medical treatment pathways for children with Crohn’s disease. The aim of this review was to explore the impact of a range of dietary treatments, including the capability of preserving the mucosal barrier, during the maintenance phase of Crohn’s disease. Methods: Randomised controlled trials and cohort studies were retrieved from five databases (Cochrane library, MEDLINE, EMBASE, ScienceDirect, and Web of Science) and through hand searching (last search: June 2025). In the inclusion criteria, this review only included studies that directly assessed children with Crohn’s disease who achieved clinical remission after the induced phase but simultaneously appeared to have signs of inflammation. Results: Six studies were identified, three of which reported outcomes directly associated with the mucosal barrier, while the other studies reported intestinal inflammation and nutritional status. A range of dietary approaches were investigated, with mixed outcomes. A carbohydrate-based diet had a mixed-effect influence on the mucosal barrier, whereas an exclusion diet significantly reduced intestinal inflammation (p = 0.01). One study reported that bovine colostrum (BC) milk (a novel approach) demonstrated mucosal integrity improvement, while the timing of partial enteral nutrition (PEN) also improved nutritional status. Importantly, compliance with all these strict regimes is complex and difficult to implement, even with the support of a dietitian. Conclusions: Consideration of the most appropriate dietary approach within CD management including remission has reported mixed effects to date. Further research is needed, especially to establish the benefits and any negative consequences of dietary intervention more clearly, and especially regarding mucosal integrity. Full article

In the North China Plain (NCP), wind and rain during the grain-filling period of winter wheat can cause lodging. The second basal internode (I2), a key load-bearing structure, plays a central role in yield stability. This study, under a constant nitrogen (N) application rate of 270 kg ha⁻¹, aimed to clarify how nitrogen basal-to-topdressing ratios regulate I2 characteristics to balance lodging resistance and yield increase. Field experiments were conducted across two seasons with three cultivars and three nitrogen split ratios (5:5, CK; 3:7, N1; and 7:3, N2). Dynamic measurements of I2 mechanical properties, morphology, anatomy, and composition were taken, and structural equation modeling (SEM) was used for analysis. Results showed that the culm lodging resistance index (CLRI) decreased by 41.8% from flowering to milk stage under all treatments, with CLRI at the milk stage of lodging treatments between 0.11 and 0.15. SEM supported a composition–structure–lodging resistance–yield chain, with CLRI as the key mediator. The N1 treatment significantly improved CLRI at all stages and increased yield by 12.2% compared to CK, making it a recommended nitrogen strategy for improving both yield and lodging resistance. These findings provide agronomically applicable nitrogen management guidelines for high-yield winter wheat systems. Full article

Cold thermal energy storage (CTES) has emerged as a critical clean-energy technology for enhancing postharvest management in rural agricultural supply chains, where losses often exceed 20–40% due to inadequate cooling infrastructure and unreliable electricity. This review synthesizes the recent literature on CTES systems, including ice-, chilled-water-, and phase-change material (PCM)-based storage, with a focus on smart-farm integration, IoT-based monitoring, predictive control, and solar photovoltaic (PV) energy coupling. Trends in village-level cold rooms, micro-dairy milk cooling, and fruit–vegetable storage are critically examined, highlighting efficiency, resilience, and scalability relative to battery-dominant and conventional refrigeration systems. Current research gaps are identified in multi-scale modeling, PCM stability, state-of-charge estimation, techno-economic optimization, and AI-based operational strategies. Addressing these gaps is essential to realizing sustainable, low-carbon, and energy-efficient rural cold chains. Full article

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with a five-year survival rate of only 26%, primarily due to late-stage diagnosis and limited treatment options. Exosomes, nanosized extracellular vesicles released by nearly all cell types, have emerged as promising tools in both diagnostics and therapeutics. Their unique composition containing proteins, lipids, and nucleic acids reflects the molecular profile of their cell of origin, making them excellent candidates for non-invasive early detection biomarkers. For therapeutic applications, exosomes offer biocompatible, low-immunogenicity platforms capable of delivering diverse therapeutic agents, including small molecules, siRNAs, and antimetabolites, directly to tumor cells while minimizing systemic toxicity. Functionalization strategies, such as folic acid tagging, have further enhanced tumor specificity, especially in cancers with high folate receptors. However, clinical translation is hindered by challenges including lack of standardized isolation and characterization methods, high production costs, and regulatory uncertainties. Despite these limitations, ongoing research continues to optimize exosome production, targeting, and integration with conventional therapies. Milk- and colostrum-derived exosomes have shown promising potential due to their abundance, scalability, oral bioavailability, and safety. Collectively, exosomes represent a transformative approach in lung cancer management, with the potential to improve early diagnosis, enhance therapeutic efficacy, and reduce adverse effects, thereby offering a path toward more personalized and effective cancer care. Full article

A cross-sectional study was carried out on small-scale dairy farms in Paraíba State, Brazil, to evaluate the prevalence and anatomical distribution of integument injuries in grazing dairy cows. Twelve herds (n = 12) were assessed, recording herd size, milk yield, and daily hours of pasture access. The integument of five body regions (back/shoulder/neck, carpus, flank/side/udder, tarsus, and hindquarters) was scored for hairless spots, lesions, and swellings (0 = absent; 1 = present). Among 335 cows observed, 267 (81.5%) presented at least one injury. The most frequent conditions were hairless patches on the hock (65.4 ± 5.03%), lesions on the flank/side/udder (34.5 ± 1.46%), and swelling in the back/shoulder/neck region (52.9 ± 5.86%). Cluster analysis revealed distinct patterns of integument injuries among cows. The high prevalence of integument injuries indicates that even in grazing systems, welfare concerns persist. Neck swelling and hairless spots on the hock were the most common problems, emphasizing the need for improved management and environmental practices to enhance welfare outcomes. These findings have practical implications for welfare assessment and management strategies in tropical grazing dairy systems. Full article

Background: Ankyloglossia is a congenital anomaly characterized by restricted tongue mobility due to a short, thick, or tight lingual frenulum. Methods: This narrative review synthesizes current concepts on etiology, clinical presentation, diagnostic approaches, functional implications, and management for ankyloglossia in newborns. Results: Ankyloglossia can compromise breastfeeding dynamics, manifesting as suboptimal latch, maternal nipple pain, and inefficient milk transfer, and may influence orofacial function if unrecognized. Because anatomical appearance alone does not reliably predict function, evaluation should prioritize structured functional assessments over purely morphological descriptors. Management should be individualized and stepwise, beginning with lactation support and positioning strategies, and progressing to frenotomy when clear functional limitation persists. In appropriately selected cases, timely intervention can improve feeding efficiency and caregiver comfort while minimizing disruptions to early bonding and nutrition. Post-procedure follow-up is important to confirm functional gains and address residual feeding mechanics. Conclusions: A coordinated, multidisciplinary approach aligns diagnosis and treatment with the infant’s functional needs and family goals, promoting safe, effective, and patient-centered care. Full article

Background/Objectives: Antimicrobial agents have revolutionized disease management in humans and animals; however, their misuse and overuse have accelerated the emergence and spread of antimicrobial resistance (AMR) and antimicrobial resistance genes (ARGs). Dairy farms are recognized as potential hotspots for ARG dissemination, particularly through Escherichia coli, which acts as a reservoir and vector of ARGs, enabling their horizontal transfer via plasmids and other mobile genetic elements. This study aimed to characterize the genomic diversity, ARG profiles, plasmid content, and phylogenetic relationships of E. coli isolated from dairy farm environments and milk using whole-genome sequencing. Methods: A total of 31 E. coli isolates recovered from soil, effluent, cow dung, and milk samples underwent deoxyribonucleic acid extraction, library preparation, and sequencing on the Illumina MiSeq platform, followed by comprehensive bioinformatic analysis. Results: The E. coli isolates exhibited 20 distinct sequence types, including one novel sequence type. Plasmids were detected in 71% of the isolates, with the IncF plasmid family being the most predominant. Furthermore, 12 ARG groups were identified, with β-lactam resistance genes detected in 67.7% of isolates. Notably, blaCTX-M genes were identified in all phenotypically confirmed extended-spectrum β-lactamase-producing isolates. Additional ARGs, including those conferring resistance to tetracyclines (tet(A), tetX4), quinolones (qnrS1), aminoglycosides (aph, aad, ant), and folate pathway inhibitors (dfr and sul), were widely distributed throughout the samples. Phylogenetic analysis revealed clustering of isolates from different sample types, particularly among ST58 isolates, suggesting cross-environmental transmission. Conclusions: This study demonstrates that E. coli from dairy farm environments harbor diverse ARGs and plasmids, confirming their role as reservoirs of AMR. These findings underscore the importance of prudent antimicrobial use, routine genomic surveillance, and enhanced biosecurity measures to limit cross-environmental transmission. Full article

The effects of reproductive technologies, namely, artificial insemination (AI) and multiple ovulation embryo transfer (MOET), on the production, health, and longevity of Holstein–Friesian cows were evaluated. Data were obtained from the time period between 2017 and 2024 on a Hungarian dairy farm and consisted of 1783 cows (1544 AI and 239 MOET). Deep-frozen semen from identical bulls was used for both the AI and MOET groups. Disease incidence, productive life, and early-lactation milk production phenotypes were collected in these cows. MOET cows demonstrated significantly higher milk yield during the first 100 days of lactation but had a 43.9% greater risk of culling compared with AI cows (p < 0.05). Metabolic and reproductive disorders were the most common reasons for culling cows, with increased frequency of health issues correlating with higher culling risk ratios (p < 0.05). While MOET cows showed lower incidences of metabolic disorders, reproductive problems, and mastitis, their shorter productive lifespan likely limited overall disease exposure. Nevertheless, when MOET cows experienced illness, the impact was more severe, particularly in relation to metabolic issues (p < 0.05). These findings highlight trade-offs between improved genetic potential and health resilience in MOET-derived cows. Despite their higher productivity, their management may require greater health vigilance. This study offers practical insights for dairy producers in selecting reproductive strategies to balance genetic gain, herd health, and longevity under intensive production systems. Full article

The bovine milk microbiome is a complex and dynamic microbial ecosystem, comprising both commensal and pathogenic bacteria. Its composition is shaped by endogenous factors, including udder physiology, lactation stage, and health status, particularly mastitis, as well as by exogenous factors, such as housing conditions, farm infrastructure, milking practices, and post-milking processing. Mastitis not only alters milk quality but also induces persistent dysbiosis that may persist even after clinical recovery, highlighting the need for continuous microbiome monitoring to ensure milk safety. Advances in molecular and metagenomic techniques have enabled the detection of microbial taxa that are difficult to identify using traditional culture-based methods. However, challenges remain due to low microbial biomass, reagent contamination, and the inability to distinguish live from dead bacteria, all of which complicate accurate characterization. Environmental contamination from skin, air, and equipment, along with microbial shifts during transport, storage, pasteurization, and product separation, further modulate microbial communities. While mastitis-related changes in milk microbiota have been extensively studied, the effects of other bovine diseases and systemic health conditions remain largely unexplored, constituting a critical knowledge gap. Understanding the factors that shape milk microbial communities is essential for ensuring dairy product safety, optimizing herd management, and developing microbiome-based innovations in milk production. Full article

Heat stress is a significant problem in dairy production that has detrimental effects on milk production, animal well-being and reproductive function. These effects are predicted to worsen due to climate change. With a focus on South African production systems, this review assesses the potential of combining precision livestock farming (PLF) and genomic selection (GS) technology to identify, measure and reduce heat stress in dairy cattle. In addition to PLF tools like wearable sensors, rumen boluses, infrared thermography, GPS- and weather-based decision-support systems, pertinent literature was reviewed to evaluate genomic approaches such as heritability estimates and genome-wide association studies identifying selection signatures for thermotolerance. While advances in genomic techniques have improved the identification of thermotolerance markers and the accuracy of breeding values for heat tolerance, evidence from recent studies shows that PLF technologies can accurately detect early physiological and behavioural indicators of heat stress in real time. The ability to select climate-resilient animals under realistic farm conditions is improved by combining high-resolution phenotypic data from PLF systems with genetic data. Overall, the review concludes that combining PLF and GS provides a useful and complementary approach to enhance the detection of heat stress, facilitate well-informed management choices and hasten the development of thermotolerant dairy cattle, all of which contribute to more sustainable dairy production under rising temperatures. Full article

The sale of raw milk via vending machines represents a well-established distribution model in many European countries, including Switzerland. As part of this study, data on the microbiological quality of raw milk sold via vending machines in Switzerland were collected. A total of 124 raw milk samples from 124 raw milk vending machines across Switzerland were analysed. In addition to standard hygiene parameters (TVC and E. coli), the scope of the investigation particularly included foodborne pathogens as well as methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase (ESBL)-producing Enterobacterales. Isolates were further characterised by whole-genome sequencing. Shiga toxin-producing Escherichia coli (STEC) were detected in 3.2%, Staphylococcus aureus was detected in 12.1%, Listeria monocytogenes was detected in 2.4%, Campylobacter spp. were detected in 1.6%, Yersinia enterocolitica was detected in 29.8%, and Salmonella spp. were detected in 0% of the samples. MRSA and ESBL-producing Enterobacterales were each detected in 0.8% of samples. The results highlight the potential risk of foodborne infections associated with the consumption of untreated raw milk, as well as hygiene deficiencies linked to several raw milk vending machines. Based on the generated data, the importance of the requested heat treatment of raw milk in Switzerland is clearly underscored. Furthermore, more precise and binding guidelines for self-monitoring and the management of raw milk vending machines appear necessary. Full article