Search Results (861)

In fresh produce cold chain last-mile delivery, the highly dispersed customer base leads to exorbitant delivery costs, posing the greatest challenge for cold chain enterprises. Achieving a symmetrical balance between cost-efficiency, environmental sustainability, and service quality is a fundamental pursuit in logistics system optimization. This paper proposes integrating the crowd-shipping logistics model—characterized by internet platform sharing and flexibility—into the delivery service. It incorporates and extends features such as cold chain delivery, mixed fleets using gasoline and diesel vehicles (GDVs), electric vehicles (EVs), partial charging strategies for EVs, and time-of-use electricity pricing into the crowd-shipping model. A joint delivery mode combining traditional professional delivery (using GDVs and EVs) with crowd-shipping is proposed, creating a symmetrical collaboration between centralized fleet management and distributed social resources. The challenges associated with utilizing occasional drivers (ODs) are analyzed, along with the corresponding compensation decisions and allocation-related constraints. A route optimization model is constructed with the objective of minimizing total cost. To solve this model, an Improved Whale Optimization Algorithm (IWOA) is proposed. To further enhance the algorithm’s performance, an adaptive variable neighborhood search is embedded within the proposed algorithm, and four local search operators are applied. Using a case study of 100 customer nodes, the joint delivery mode with OD participation reduces total delivery costs by an average of 24.94% compared to the traditional professional vehicle delivery mode, demonstrating a more symmetrical allocation of logistical resources. The experiments fully demonstrate the effectiveness of the joint delivery model and the proposed algorithm. Full article

Background: The Hajj pilgrimage, a significant religious event, presents unique health challenges due to the large number of participants and the physical demands of the pilgrimage. Despite efforts by Saudi health authorities to provide comprehensive health services, the effectiveness of these interventions relies heavily on pilgrims’ knowledge of available services and emergency measures. Objectives: The aim of this study is to assess the level of knowledge of health services among Hajj pilgrims in Saudi Arabia during the 1445 H (2024 G) season and its associated demographic and health-related factors. Methods and Materials: This cross-sectional study was conducted during the 1445 H (2024 G) Hajj season with 1215 pilgrims, 51.7% male. Participants were randomly selected from selected pilgrimage accommodations or passing through the airport in Jeddah. Data were collected through face-to-face interviews using a structured questionnaire covering demographics, health characteristics, and knowledge of health services. Results: The study found that 62.1% of participants correctly believed that health services during Hajj were free of charge. Furthermore, 44.4% were aware of the emergency health number, with 31.5% exhibiting good knowledge. Bivariate analysis showed that younger participants had better knowledge (p < 0.001), and males were more likely than females to demonstrate partial or good knowledge (p = 0.011). Participants with university education were significantly more likely to have good knowledge, with 29.6% demonstrating good knowledge compared to 7.4% of illiterate participants (p < 0.001). Geographic region was also a factor, with 48.9% of Middle Eastern participants exhibiting good knowledge, compared to 27.1% of African and 23.6% of Asian participants (p < 0.001). However, multivariable logistic regression, revealed that only younger age (OR = 0.98, p = 0.005), university education (OR = 1.96, p = 0.024), and being from the Middle East (OR = 1.61, p = 0.009) were significant predictors of good knowledge of health services. Conclusions: The study identified significant gaps in pilgrims’ knowledge of health services during Hajj, with younger age, higher education, and Middle Eastern geographic region identified as independent predictors of better knowledge. These findings suggest the need for targeted health education initiatives, particularly for older pilgrims, those with lower educational attainment, and individuals from regions with lower awareness levels, to improve knowledge and potentially enhance health outcomes during Hajj. Full article

This study investigates consumer behavior in electric vehicle (EV) adoption, focusing on how factors like convenience, accessibility, technological perception, and cost influence the travel patterns and usage behavior of EV drivers in Thailand. This study aims to address the research gap in the comparative behavior between electric vehicles and public transport in a developing country. Using a quantitative approach, the study collected data via surveys distributed online and face-to-face interviews with a stratified sample of 398 respondents. The survey assessed the relationships between convenience and accessibility, technology perception, cost of ownership, and travel patterns using structural equation modeling (SEM). The findings reveal that convenience and accessibility significantly affect consumer perceptions of technology and the cost of ownership, which, in turn, influences travel patterns. Technology perception and performance serve as partial mediators, suggesting that improving the infrastructure enhances EV adoption. Additionally, the cost of ownership, including long-term savings, positively impacts usage behavior. This study provides key insights for policymakers and urban planners aiming to promote the adoption of EVs. Enhancing charging infrastructure, offering government incentives, and improving public awareness of long-term cost benefits are recommended strategies. These findings are particularly relevant in urban environments and offer guidance for developing infrastructure policies that align with consumer preferences. Full article

Centrifugal filtration devices are increasingly being used to separate (bio)molecules thanks to their molar masses. This is partly due to their ease of use, with sample preparation requiring no complicated protocol and often being able to be run as is. Nevertheless, several limitations have been highlighted in the literature, such as proteins’ selectivity according to their molar masses, clogging problems and some post-separation quantification issues. We wanted to test the real potential of the centrifugal filtration devices as a characterization tool, by verifying their specificity using a library of peptides and proteins. The impact of the peptide charge on separation performance as well as the impact of biological material concentration and centrifugation rate were evaluated using three membranes with different cut-offs. A good specificity was confirmed: biological materials that have molar masses which are below the membrane cut-off can pass almost completely through the membrane, while those with molar masses above the membrane cut-off are almost fully retained. The findings proved more problematic when protein mixtures were analyzed: despite still having good specificity, biological materials with molar masses below the membrane cut-off only partially crossed the membranes, due to clogging effects, making quantification of the initial mixture incorrect. It is therefore essential to be very careful when working with centrifugal filtration devices, as their use requires precise and relevant controls, without necessarily being able to optimize the separation of mixtures. Thus, this remains far from an easy and ready-to-use system. Full article

To study the adsorption of lanthanide (Ln) atoms on graphene containing a Stone–Wales defect, we used a cluster model (SWG) and performed calculations at the PBE-D2/DNP level of the density functional theory. Our previous study, where the above combination was complemented with the ECP pseudopotentials, was only partially successful due to the impossibility of calculating terbium-containing systems and a serious error found for the SWG complex with dysprosium. In the present study we employed the DSPP pseudopotentials and completely eliminated the latter two failures. We analyzed the optimized geometries of the full series of fifteen SWG + Ln complexes, along with their formation energies and electronic parameters, such as frontier orbital energies, atomic charges, and spins. In many regards, the two series of calculations show qualitatively similar features, such as roughly M-shaped curves of the adsorption energies and trends in the changes in charge and spin of the adsorbed Ln atoms, as well as the spin density plots. However, the quantitative results can differ significantly. For most characteristics we found no evident correlation with the lanthanide contraction. The only dataset where this phenomenon apparently manifests itself (albeit to a limited and irregular degree) is the changes in the closest Ln^…C approaches. Full article

Accurate state-of-health (SOH) estimation of lithium iron phosphate (LiFePO₄) batteries is critical for ensuring the safety and performance of electric vehicles, particularly under extreme operating conditions. This study presents a data-driven SOH prediction framework based on high-frequency electrochemical impedance spectroscopy (EIS) measurements conducted at −5 °C across various states of charge (SOCs). Feature parameters were extracted from the impedance spectra using equivalent circuit modeling. These features were optimized through Bayesian weighting and subsequently fed into three machine learning models: Random Forest (RF), Gradient Boosting (GB), and Extreme Gradient Boosting (XGB). To mitigate SOC-dependent variations, the models were trained, validated, and tested using features from different SOC levels for each aging cycle. This work provides a practical and interpretable approach for battery health monitoring using high-frequency EIS data, even under sub-zero temperature and partial-SOC conditions. The findings offer valuable insights for developing SOC-agnostic SOH estimation models, advancing the reliability of battery management systems in real-world applications. Full article

This study employs molecular orbital (MO) analysis, density of states (DOS) analysis, and advanced techniques such as charge density difference (CDD), transition density matrix (TDM), transition electric dipole moment density (TEDM), and transition magnetic dipole moment density (TMDM) to systematically investigate the electronic structure characteristics of Fc-[8]CPP and Fc-[11]CPP. Using density functional theory (DFT) and time-dependent DFT (TD-DFT), the π-electron delocalization properties and optical behaviors of these molecules were analyzed. Furthermore, their responses to external electromagnetic fields were explored through electronic circular dichroism (ECD) and Raman spectroscopy, comparing chiral optical responses and electron–vibration coupling effects to elucidate their photophysical properties. The results reveal that the HOMO-LUMO energy gaps of Fc-[8]CPP and Fc-[11]CPP are 5.81 eV and 5.95 eV, respectively, with a slight increase as ring size grows; Fc-[8]CPP exhibits a stronger chiral response, while Fc-[11]CPP shows reduced chirality due to enhanced symmetry. Finally, TD-DFT calculations demonstrate that their optical absorption is dominated by localized excitations with partial charge transfer contributions. These findings provide a theoretical foundation for designing conjugated macrocyclic materials with superior optoelectronic performance. Full article

This work presents new results and conclusions on nanomembrane filtration and reverse osmosis of Mavrud red wine, produced in Bulgaria. The experiments were focused on lowering the alcohol content while preserving the valuable substances in the wine. Commercially available nanomembranes were used (Alfa Laval NF99HF, Alfa Laval RO99, NADIR NP030P). Two modes of nanofiltration (concentration mode and diafiltration mode, including constant volume diafiltration and two-step diafiltration) and reverse osmosis were employed for this study. The nanofiltration membranes (Alfa Laval NF99HF, NADIR NP030P) used for wine dealcoholization showed high separation effectiveness. Several wine components were recognized as indicators to be monitored during the process: carboxylic acids (citric, tartaric, malic, succinic, acetic); monosaccharides (glucose, fructose); alcohol (ethanol). The monitoring of the named compounds was performed with an HPLC-RID system on an H-charged ion exclusion analytical column. Based on the analysis of the collected samples, it could be stated that the alcohol content in the wine was lowered from 11.8% to 4.3 vol% of ethanol, when the sequential diafiltration mode of operation is used. Content change depends on the type of molecule; for example, in most cases the citric acid is strongly retained (Rej > 90%) by the membrane, whereas the acetic acid could permeate significantly (Rej < 20%). The obtained results present valuable information about the changes in the composition of the Mavrud wine which will aid in the preservation of the chemical composition and valuable substances in the event of future full or partial dealcoholization of this wine variety. Full article

Vanadium-based electrode materials are limited in practical applications, due to their low energy density, cycling instability, and poor electrochemical stability. To address these limitations, a wood-derived vanadium oxide (VO_x) electrode was developed through sol–gel assembly followed by thermal annealing, in which VO_x aerogel formed within the vertically aligned wood channels, resulting in a continuous porous network to mitigate particle aggregation and enhance ion diffusion. After thermal annealing at 800 °C, V⁵⁺ partially converts to V⁴⁺, forming a mixed-valence heterostructure that significantly increases the density of redox-active sites and facilitates efficient charge transfer. The optimized VO_x@Wood-800 °C (VOW-800) electrode exhibits a high specific capacitance of 317.8 F g⁻¹ at 2 mA cm⁻² and a specific surface area of 111.22 m⁻² g⁻¹, attributed to the synergistic effects of the mixed-valence structure and the enhanced ion accessibility provided by the wood-derived porous framework. This approach offers a promising pathway for developing vanadium-based electrodes with improved charge storage capacity and interface stability. Full article

Internal conductive defects in composite insulators severely degrade their insulation performance and are considered concealed defects, posing a significant threat to the safe and stable operation of the power grid. Focusing on this issue, this study develops an electro-thermal multi-physical field simulation model and uses finite element analysis to investigate the electric field distribution and temperature rise characteristics. Composite insulator specimens with varying defect lengths were fabricated using the electrical erosion test. Charged tests were then conducted on these defective specimens, as well as on field-decommissioned specimens. The impact of internal conductive defects on the infrared, ultraviolet, and electric field distribution characteristics of composite insulators during operation was analyzed. The results indicate that the surface electric field of composite insulators with internal conductive defects becomes highly concentrated along the defect path, with a significant increase in electric field strength at the defect’s end. The maximum field strength migrates toward the grounded end as the defect length increases. Conductive defects lead to partial discharge and abnormal temperature rise at the defect’s end and the bending points of the composite insulator. The temperature rise predominantly manifests as “bar-form temperature rise,” with temperature rise regions correlating well with discharge areas. Conductive defects accelerate the decay-like degradation process of composite insulators through a positive feedback loop formed by the coupling of electric field distortion, Joule heating, material degradation, and discharge activity. This study identifies the key characteristics of electrical and temperature rise changes in insulators with conductive defects, reveals the deterioration evolution process and degradation mechanisms of insulators, and provides effective criteria for on-site diagnosis of conductive defects. Full article

Protein–polyelectrolyte nanostructures assembled via electrostatic interactions offer versatile applications in biomedicine, tissue engineering, and food science. However, several open questions remain regarding their intermolecular interactions and the influence of external conditions—such as temperature and pH—on their assembly, stability, and responsiveness. This study explores the formation and stability of networks between poly(acrylic acid) (PAA) and lysozyme (LYZ) at the nanoscale upon thermal treatment, using a combination of experimental and simulation measures. Experimental techniques of static and dynamic light scattering (SLS and DLS), Fourier transform infrared spectroscopy (FTIR), and circular dichroism (CD) are combined with all-atom molecular dynamics simulations. Model systems consisting of multiple PAA and LYZ molecules explore collective assembly and complexation in aqueous solution. Experimental results indicate that electrostatic complexation occurs between PAA and LYZ at pH values below LYZ’s isoelectric point. This leads to the formation of nanoparticles (NPs) with radii ranging from 100 to 200 nm, most pronounced at a PAA/LYZ mass ratio of 0.1. These complexes disassemble at pH 12, where both LYZ and PAA are negatively charged. However, when complexes are thermally treated (TT), they remain stable, which is consistent with earlier findings. Atomistic simulations demonstrate that thermal treatment induces partially reversible structural changes, revealing key microscopic features involved in the stabilization of the formed network. Although electrostatic interactions dominate under all pH and temperature conditions, thermally induced conformational changes reorganize the binding pattern, resulting in an increased number of contacts between LYZ and PAA upon thermal treatment. The altered hydration associated with conformational rearrangements emerges as a key contributor to the stability of the thermally treated complexes, particularly under conditions of strong electrostatic repulsion at pH 12. Moreover, enhanced polymer chain associations within the network are observed, which play a crucial role in complex stabilization. These insights contribute to the rational design of protein–polyelectrolyte materials, revealing the origins of association under thermally induced structural rearrangements. Full article

The mechanism by which voltage-gated ion channels open and close has been the subject of intensive investigation for decades. For a large class of potassium channels and related sodium channels, the consensus has been that the gating current preceding the main ionic current is a large movement of positively charged segments of protein from voltage-sensing domains that are mechanically connected to the gate through linker sections of the protein, thus opening and closing the gate. We have pointed out that this mechanism is based on evidence that has alternate interpretations in which protons move. Very little literature considers the role of water and protons in gating, although water must be present, and there is evidence that protons can move in related channels. It is known that water has properties in confined spaces and at the surface of proteins different from those in bulk water. In addition, there is the possibility of quantum properties that are associated with mobile protons and the hydrogen bonds that must be present in the pore; these are likely to be of major importance in gating. In this review, we consider the evidence that indicates a central role for water and the mobility of protons, as well as alternate ways to interpret the evidence of the standard model in which a segment of protein moves. We discuss evidence that includes the importance of quantum effects and hydrogen bonding in confined spaces. K⁺ must be partially dehydrated as it passes the gate, and a possible mechanism for this is considered; added protons could prevent this mechanism from operating, thus closing the channel. The implications of certain mutations have been unclear, and we offer consistent interpretations for some that are of particular interest. Evidence for proton transport in response to voltage change includes a similarity in sequence to the H_v1 channel; this appears to be conserved in a number of K⁺ channels. We also consider evidence for a switch in -OH side chain orientation in certain key serines and threonines. Full article

In applications where it is crucial that a battery is recharged from the partially discharged state in the minimum time, it is crucial to honor the technological constraints related to maximum safe battery terminal voltage and maximum continuous charging current prescribed by the battery cell manufacturer. To this end, this contribution outlines the design and comprehensive simulation analysis of an adaptive battery charging system relying on battery open-circuit voltage estimation in real time. A pseudo-random binary sequence test signal and model reference adaptive system are used for the estimation of lithium titanate battery cell electrical circuit model parameters, with the design methodology based on the Lyapunov stability criterion. The proposed adaptive charger is assessed against the conventional constant-current/constant-voltage charging system. The effectiveness of the real-time parameter estimator, along with both the adaptive and traditional charging systems for the lithium titanate battery cell, is validated through simulations and experiments on a dedicated battery test bench. Full article

Lightning strikes pose a significant risk during outdoor activities. The connection between conventionally used rescue blankets in alpine emergencies and the risk of lightning injury is unclear. This experimental study investigated whether rescue blankets made of aluminum-coated polyethylene terephthalate increase the likelihood of lightning injuries. High-voltage experiments of up to 2.5 MV were conducted in a controlled laboratory setting, exposing manikins to realistic lightning discharges. In a balanced test environment, two conventionally used brands were investigated. Upward leaders frequently formed on the edges along the fold lines of the foils and were significantly longer in crumpled rescue blankets (p = 0.004). When a lightning strike occurred, the thin metallic layer evaporated at the contact point without igniting the blanket or damaging the underlying plastic film. The blankets diverted surface currents and prevented current flow to the manikins, indicating potentially protective effects. The findings of this experimental study suggest that upward leaders rise from the edge areas of rescue blankets, although there is no increased risk for a direct strike. Rescue blankets may even provide partial protection against exposure to electrical charges. Full article

The energy transition toward greater electrification leads to incentives in public transportation fed by catenary-powered networks. In this context, emerging technological devices such as in-motion-charging vehicles and electric vehicle charging points are expected to be operated while connected to trolleybus networks as part of new electrification projects, resulting in a significant demand for power. To enable a significant increase in electric transportation without compromising technical compliance for voltage and current at grid systems, the implementation of stationary battery energy storage systems (BESSs) can be essential for new electrification projects. A key challenge for BESSs is the selection of the optimal converter topology for charging their batteries. Ideally, the chosen converter should offer the highest efficiency while minimizing size, weight, and cost. In this context, a modular dual-active-bridge converter, considering its operation as a full-power converter (FPC) and a partial-power converter (PPC) with module-shedding control, is analyzed in terms of operation efficiencies and thermal behavior. The goal is to clarify the advantages, disadvantages, challenges, and trade-offs of both power-processing techniques following future trends in the electric transportation sector. The results indicate that the PPC achieves an efficiency of 98.58% at the full load of 100 kW, which is 1.19% higher than that of FPC. Additionally, higher power density and cost effectiveness are confirmed for the PPC. Full article