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Keywords = patellofemoral pain

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10 pages, 475 KB  
Article
Task-Specific Reliability and Measurement Error of Frontal Plane Kinematics in Individuals with Patellofemoral Pain: A Preliminary Study
by Hiraku Nagahori, Isabella Keefer, Derrick Smith, Brendan Yawn, Jing Nong Liang and Kai-Yu Ho
Methods Protoc. 2026, 9(3), 76; https://doi.org/10.3390/mps9030076 (registering DOI) - 13 May 2026
Viewed by 213
Abstract
This study evaluated the test–retest reliability, standard error of measurement (SEM), and minimal detectable change (MDC) of frontal plane projection angles (FPPAs) across five single-leg tasks in individuals with patellofemoral pain (PFP). Two-dimensional video data was collected from ten individuals with predominantly unilateral [...] Read more.
This study evaluated the test–retest reliability, standard error of measurement (SEM), and minimal detectable change (MDC) of frontal plane projection angles (FPPAs) across five single-leg tasks in individuals with patellofemoral pain (PFP). Two-dimensional video data was collected from ten individuals with predominantly unilateral PFP. Participants performed single-leg squat, single-leg landing, single-leg hop, forward step-down, and lateral step-down across two testing sessions. FPPAs were measured at peak knee flexion for each task, including trunk lean angle, knee FPPA, hip FPPA, and dynamic valgus index. Test–retest reliability was assessed using intraclass correlation coefficients (ICCs). Our findings indicate that test–retest reliability and measurement error for trunk and lower limb FPPA varied across tasks in individuals with PFP. The lowest ICC was observed for hip FPPA, particularly during single-leg squat and lateral step-down tasks. Among the five tasks tested, the single-leg squat appeared to be the most demanding task, demonstrating the lowest ICCs, and highest SEM and MDC values across all four outcome measures (trunk lean angle, knee and hip FPPAs, and dynamic valgus index). The dynamic valgus index consistently showed larger SEM and MDC values than isolated hip or knee FPPAs, likely reflecting compounded measurement errors across segments. These findings provide preliminary insights, though confirmation in larger samples in persons with PFP is warranted. Full article
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14 pages, 440 KB  
Article
Agreement Between Video-Based and In-Person Assessment in Patients with Knee Pain—A Prospective Repeated-Measures Pragmatic Study
by Stefanos Karanasios, Athanasios Koutsouradis, Christina Mavrogiannopoulou, Vasiliki Sakellari and George Gioftsos
J. Clin. Med. 2026, 15(9), 3200; https://doi.org/10.3390/jcm15093200 - 22 Apr 2026
Viewed by 377
Abstract
Background: Digital health has accelerated telehealth uptake, yet evidence comparing video-based musculoskeletal assessment with traditional in-person examination is limited. This study evaluated the concurrent validity and interrater reliability of video-based physiotherapy assessment versus face-to-face assessment in patients with knee pain. Methods: Patients with [...] Read more.
Background: Digital health has accelerated telehealth uptake, yet evidence comparing video-based musculoskeletal assessment with traditional in-person examination is limited. This study evaluated the concurrent validity and interrater reliability of video-based physiotherapy assessment versus face-to-face assessment in patients with knee pain. Methods: Patients with knee pain underwent randomized consecutive in-person and video-based assessments by experienced musculoskeletal physiotherapists. Clinical diagnoses were categorized into seven groups (red flag, yellow flag, arthrogenic, tendinopathy, patellofemoral pain, muscle sprain, neurogenic). Primary outcomes were intermethod agreement and Cohen’s kappa; sensitivity, specificity, PPV, NPV, and interrater reliability for video assessments were also reported. Results: Forty-five participants (mean age 38 ± 6.5 years; 55.6% female) completed the study. In-person and video-based assessments produced identical diagnoses in 43/45 cases (Cohen’s κ = 0.92, p < 0.001). Telehealth accuracy was high across all diagnostic categories (90–100%). Interrater agreement between video-based assessors was 93.3% (κ = 0.89, p < 0.001). Agreement between assessments was moderately associated with KOOS (r = 0.312, p = 0.037). Conclusions: In this selected pragmatic sample, video-based physiotherapy assessment demonstrated high concurrent agreement and excellent interrater reliability with face-to-face assessment. Given the study’s sample size, repeated-measures design, and lack of an independent reference standard, these results indicate feasibility and intermethod agreement rather than diagnostic equivalence. Video assessment may be a feasible option for triage and management in selected settings, but further research in larger, more diverse populations and evaluation against independent reference standards is required. Full article
(This article belongs to the Special Issue Updates on Physiotherapy in Pain Management)
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20 pages, 1447 KB  
Review
Patellar Maltracking in Total Knee Arthroplasty: Mechanisms, Prevention and Treatment
by Michał Krupa, Joachim Pachucki, Iga Wiak, Rafał Zabłoński, Paweł Kasprzak, Łukasz Pulik and Paweł Łęgosz
Prosthesis 2026, 8(4), 38; https://doi.org/10.3390/prosthesis8040038 - 10 Apr 2026
Viewed by 683
Abstract
Patellar maltracking is among the most common causes of anterior knee pain after total knee arthroplasty (TKA), underscoring the need for accurate prevention and treatment. Therefore, the purpose of this narrative review is to provide a comprehensive overview of current evidence on post-TKA [...] Read more.
Patellar maltracking is among the most common causes of anterior knee pain after total knee arthroplasty (TKA), underscoring the need for accurate prevention and treatment. Therefore, the purpose of this narrative review is to provide a comprehensive overview of current evidence on post-TKA tracking, focusing on component alignment, preoperative patient assessment, and revision treatment options. A PubMed database search was performed, leveraging the literature from the last 20 years, and the results were qualitatively synthesized. According to current studies, several precautions should be taken to prevent patellofemoral stress and, consequently, patellar maltracking, such as avoiding internal rotation, valgus alignment, and excessive flexion of the femoral component and internal rotation of the tibial component. Regarding alignment strategies, kinematic alignment appears to offer potential benefits over mechanical alignment in certain functional outcomes and patient satisfaction scores. However, these differences should be interpreted cautiously as they may not always exceed the minimal clinically important difference. Furthermore, recent evidence indicates that quadriceps biomechanics influence TKA outcomes, potentially suggesting that conventional surgical approaches may need to be individualized, though these preliminary findings require prospective validation. Currently, robotic-assisted surgery represents a developmental direction for patient-tailored interventions and offers great promise for better prosthesis customization to the individual patient. Integration of imaging data with dynamic soft-tissue assessment enables more predictable reconstruction of joint kinematics. Regarding surgical treatment, the selection of specific methods requires a prior clinical and radiographic assessment. Indications range from patellar maltracking direction and component malrotation to patient preferences and rehabilitation potential. Ultimately, the future of TKA relies on personalized interventions to prevent complications and improve patient outcomes. This evolution is driven by the shift from mechanical alignment to kinematic alignment, alongside quadriceps tendon assessment and intraoperative robotic-assisted measurement, all aimed at optimizing the accuracy of implant positioning. Full article
(This article belongs to the Section Orthopedics and Rehabilitation)
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13 pages, 3192 KB  
Review
Anterior Knee Pain and Excessive External Tibial Torsion in Female Patients: Rationale and Outcomes of Rotational Tibial Osteotomy
by Vicente Sanchis-Alfonso, Jesus Castellano-Curado, Erik Montesinos-Berry, Santiago Ferrer-Piquer and Robert A. Teitge
J. Clin. Med. 2026, 15(5), 2015; https://doi.org/10.3390/jcm15052015 - 6 Mar 2026
Viewed by 727
Abstract
Excessive external tibial torsion (ETT) is a recognized cause of anterior knee pain (AKP). In patients with excessive ETT, placing the foot forward during gait causes the knee joint to point inward, increasing the Q-angle and the lateral quadriceps vector. In appropriately selected [...] Read more.
Excessive external tibial torsion (ETT) is a recognized cause of anterior knee pain (AKP). In patients with excessive ETT, placing the foot forward during gait causes the knee joint to point inward, increasing the Q-angle and the lateral quadriceps vector. In appropriately selected cases, internal rotational tibial osteotomy is a reliable treatment option for symptomatic excessive ETT, yielding favorable outcomes with minimal complications. Nevertheless, no universally accepted torsion threshold exists to guide surgical decision-making, and evidence remains limited regarding the optimal anatomic level for performing the osteotomy. Full article
(This article belongs to the Section Orthopedics)
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14 pages, 1007 KB  
Article
Immediate Effect of Rigid Taping and Patella-Stabilizing Brace on Proprioception, Functionality, and Balance in Patients with Patellofemoral Pain Syndrome: A Randomised Controlled Trial
by Ömer Naci Ergin, Ayşenur Erekdağ, İrem Nur Şener, Pelin Vural and Yıldız Analay Akbaba
J. Clin. Med. 2026, 15(5), 1936; https://doi.org/10.3390/jcm15051936 - 4 Mar 2026
Viewed by 500
Abstract
Background: Patellofemoral pain syndrome (PFPS) is a common musculoskeletal disorder that involves various biomechanical factors, including the altered positioning of the patella, weakness of the lower extremity muscles, delayed activation of the vastus medialis muscle, and excessive pronation of the foot. Although [...] Read more.
Background: Patellofemoral pain syndrome (PFPS) is a common musculoskeletal disorder that involves various biomechanical factors, including the altered positioning of the patella, weakness of the lower extremity muscles, delayed activation of the vastus medialis muscle, and excessive pronation of the foot. Although the short- and long-term effects of external support among the recommended conservative treatment methods for PFPS have been examined, there remains a lack of consensus regarding their impacts. This study was conducted to investigate the immediate effects of braces and rigid taping applied to control pain on proprioception, functional status, and balance in patients with PFPS, and to compare these outcomes with normative values obtained from healthy individuals. Methods: The study included 18 patients with PFPS and 18 healthy individuals who met the inclusion criteria. Through randomization of the intervention sequence, patients were evaluated under conditions of rigid taping, support, or without any support. Their pain levels before and after the application were assessed using the Visual Analog Scale; their functional status was evaluated with the Kujala Patellofemoral Scoring, the 10-Step Up Test, and the Squat; their balance performance was measured using the Y-Balance Test and the Single Leg Stance Test; and their proprioception was assessed with the Joint Position Sense Test. Results: It has been determined that rigid taping and bracing have similar effects in the immediate management of pain, proprioception, functional status, and balance issues in patients with PFPS. The interventions were observed to bring patients’ static balance and proprioception parameters closer to the values seen in healthy individuals. Conclusions: Rigid taping and bracing are both effective interventions in the management of PFPS, offering benefits such as pain relief, prevention of proprioceptive deficits, mitigation of balance impairments, and enhancement of functional outcomes. The selection of the most appropriate modality should be based on the individual patient’s characteristics and tolerance levels. Full article
(This article belongs to the Section Orthopedics)
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10 pages, 555 KB  
Article
Does Patellar Resurfacing Improve Outcomes in Valgus Osteoarthritis with Compromised Patellofemoral Joint Status? A Retrospective Consecutive Comparative Study
by Jae-Sung Seo, Jung-Kwon Bae, Seong-Kee Shin, Hyung-Gon Ryu, Kyu-Jin Kim and Ji Seon Chae
J. Clin. Med. 2026, 15(4), 1587; https://doi.org/10.3390/jcm15041587 - 18 Feb 2026
Viewed by 369
Abstract
Background/Objectives: The benefit of patellar resurfacing (PR) in total knee arthroplasty (TKA) remains controversial. No previous study has examined the impact of PR in valgus osteoarthritis (OA) with compromised patellofemoral joint (PFJ) status. Methods: We retrospectively reviewed 2250 primary TKAs performed [...] Read more.
Background/Objectives: The benefit of patellar resurfacing (PR) in total knee arthroplasty (TKA) remains controversial. No previous study has examined the impact of PR in valgus osteoarthritis (OA) with compromised patellofemoral joint (PFJ) status. Methods: We retrospectively reviewed 2250 primary TKAs performed between 2011 and 2025. Among 152 valgus OA cases, 87 had compromised PFJ status, defined as Outerbridge grade 3–4 chondral damage or patellar tilt >10° on Merchant-view radiographs. Two surgeons with identical protocols operated during overlapping periods; one typically performed PR (n = 47) and the other did not (n = 40). Primary outcomes included the American Knee Society (AKS) score and Kujala Anterior Knee Pain Scale. Secondary outcomes included radiologic measures (HKA angle, patellar tilt, and lateral patella shift) and patellar-related complications (crepitus, fracture, subluxation, and maltracking). Results: At a mean follow-up of 7.1 years in the non-PR group and 6.5 years in the PR group, no significant differences were observed between groups in KSS function scores (non-PR 92.4 ± 3.5 vs. PR 93.0 ± 4.6, p = 0.54) or Kujala scores (non-PR 76.9 ± 3.5 vs. PR 77.7 ± 4.2, p = 0.33). Both patellar tilt and lateral patella shift showed slight postoperative reductions, but no significant difference was observed between groups (patellar tilt: non-PR 5.4° ± 0.8° vs. PR 5.7° ± 0.6°, p = 0.11; lateral patella shift: non-PR 2.4 ± 0.6 mm vs. PR 2.3 ± 0.7 mm, p = 0.75). Patellar-related complications were infrequent and showed no significant differences. Conclusions: Overall, PR did not demonstrate superior outcomes compared with non-PR in valgus OA patients with compromised PFJ status at mid-term follow-up. Full article
(This article belongs to the Special Issue Clinical Updates on Knee and Hip Arthroplasty)
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15 pages, 529 KB  
Review
Sport-Specific Considerations in ACL Reconstruction: Diagnostic Evaluation and Graft Selection
by Assala Abu Mukh, Giacomo Placella and Ki-Mo Jang
Diagnostics 2026, 16(4), 584; https://doi.org/10.3390/diagnostics16040584 - 15 Feb 2026
Cited by 1 | Viewed by 917
Abstract
Knee biomechanical demands vary across different sports due to sport- and position-specific patterns of muscle recruitment. To return to performance, athletes must adequately restore knee kinematics to regain control over the same sport mechanics that led to the initial anterior cruciate ligament (ACL) [...] Read more.
Knee biomechanical demands vary across different sports due to sport- and position-specific patterns of muscle recruitment. To return to performance, athletes must adequately restore knee kinematics to regain control over the same sport mechanics that led to the initial anterior cruciate ligament (ACL) injury. ACL graft selection should therefore minimize donor site morbidity and support sport-specific demands. This study aims to address the available evidence and guide surgical graft choice in athletes. A literature search of PubMed, MEDLINE, Scopus, and Web of Science (up to September 2025) assessed BPTB, hamstring, and quadriceps tendon autografts. Outcomes included revision, graft survival, return to sport, time to return, PROMs, anterior knee pain, donor site morbidity, and prognostic factors (age, sex). Sports were classified as pivoting, contact/collision, or endurance/non-pivoting. The results were synthesized narratively. In pivoting and cutting sports, bone–patellar tendon–bone (BPTB) autografts offer high survival rates but are associated with a high incidence of anterior knee pain, which is a substantial drawback in kneeling or flexion-intensive sports. Hamstring tendon (HT) grafts carry higher revision rates in female and younger patients, though they have low donor site morbidity that does not appear to affect long-term athletic performance. Quadriceps tendon (QT) grafts are emerging as a promising option for pivoting athletes. However, conflicting results indicate that the revision risk is comparable to that of HT grafts and possible long-standing extensor mechanism weakness. Contact and collision sports demonstrate similar trends, but kneeling and contact injuries are more common in this group. Thus, while prioritizing powerful hamstring strength, anterior knee pain symptoms should still be carefully considered. The diameter of the HT autograft should exceed 7.5 mm to ensure comparable revision outcomes with BPTB. QT grafts remain a limited-evidence attractive option. Endurance and non-pivoting athletes require fewer pivoting mechanics but rely heavily on muscle symmetry and repetitive motion. BPTB grafts are less suitable in this category due to alterations in sprint mechanics, muscle asymmetry, and repetitive patellofemoral joint loading. HT grafts provide favorable rates of return to sport, whereas evidence regarding QT graft use in non-pivoting athletes remains limited. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Sports Injuries)
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20 pages, 313 KB  
Article
Lived Experiences of Male Recreational Cyclists with Patellofemoral Pain in Al Madinah, Saudi Arabia
by Ameen Masoudi, Ushotanefe Useh, Nomzamo Charity Chemane, Bashir Bello and Nontembiso Magida
Int. J. Environ. Res. Public Health 2026, 23(2), 171; https://doi.org/10.3390/ijerph23020171 - 29 Jan 2026
Viewed by 609
Abstract
Background: Patellofemoral pain (PFP) is a prevalent overuse injury among recreational cyclists worldwide. Despite its ubiquity, little is known about the lived experiences of people with PFP, especially in Saudi Arabia, where healthcare and cultural factors may have a specific impact on how [...] Read more.
Background: Patellofemoral pain (PFP) is a prevalent overuse injury among recreational cyclists worldwide. Despite its ubiquity, little is known about the lived experiences of people with PFP, especially in Saudi Arabia, where healthcare and cultural factors may have a specific impact on how the condition is managed. The aim of this study was to explore the lived experiences of recreational cyclists with patellofemoral pain in Al Madinah, Saudi Arabia. Method: A qualitative, descriptive design using reflexive thematic analysis was employed. Eleven male recreational cyclists aged 28–44 years diagnosed with PFP were purposely recruited from Al Madinah Physical Therapy Centre. Female participants were excluded due to cultural constraints regarding sports participation. The participants consented to participate in the study and to be audio recorded. Data were collected through semi-structured interviews using an interview guide. The interview data were transcribed verbatim and thematically analysed using Atlas.ti, version 24. Results: The thematic analysis revealed six themes highlighting the multidimensional impact of PFP. The participants described localised mechanical impairment with rapid onset during activity and persistent symptoms lasting up to two weeks. Pain was exacerbated by eccentric loading and cycling-specific stressors, such as uphill riding, leading to significant anxiety and avoidance behaviours. To maintain activity, these cyclists employed adaptive strategies, including bike modifications and self-management. Notably, PFP imposed substantial cultural and social burdens, hindering spiritual practices, specifically Salah (prayer) postures, professional duties, and family caregiving. While the participants demonstrated resourcefulness through a hybrid of physiotherapy and independent research, pharmacological relief was viewed as a transient solution. Conclusions: Patellofemoral pain imposes significant multidimensional burdens on recreational cyclists in Al Madinah, which are exacerbated by cultural practices. Physiotherapy offers targeted interventions for pain relief, functional restoration, and participation enhancement, necessitating the need for culturally sensitive management programmes. Full article
18 pages, 1226 KB  
Review
The Effect of Joint Mobilization and Manipulation on Proprioception: Systematic Review with Limited Meta-Analysis
by Stelios Hadjisavvas, Irene-Chrysovalanto Themistocleous, Michalis A. Efstathiou, Elena Papamichael, Christina Michailidou and Manos Stefanakis
J. Funct. Morphol. Kinesiol. 2026, 11(1), 59; https://doi.org/10.3390/jfmk11010059 - 29 Jan 2026
Cited by 1 | Viewed by 1468
Abstract
Background: Proprioceptive deficits, commonly quantified as joint position sense error (JPSE), are frequently reported in musculoskeletal conditions. Articular manual therapy may influence afferent input and sensorimotor integration. This review synthesised the effects of joint mobilization and/or high-velocity low-amplitude (HVLA) thrust manipulation on quantitative [...] Read more.
Background: Proprioceptive deficits, commonly quantified as joint position sense error (JPSE), are frequently reported in musculoskeletal conditions. Articular manual therapy may influence afferent input and sensorimotor integration. This review synthesised the effects of joint mobilization and/or high-velocity low-amplitude (HVLA) thrust manipulation on quantitative proprioception outcomes in humans. Methods: PubMed, Scopus, CINAHL, and MEDLINE Complete were searched (from inception to November 2025) for randomized or sham-controlled trials assessing proprioception after eligible articular manual therapy. Searches were limited to English-language publications. Risk of bias was assessed using Risk of Bias 2 (RoB 2). Random-effects meta-analysis (Hedges’ g) was conducted when outcomes and time points were comparable; pooling was possible for only one outcome/time-point comparison. Certainty of evidence was assessed using GRADE. Results: Database searches yielded 483 records; after duplicate removal, 371 records were screened. Eighteen full-text articles were assessed for eligibility, of which 11 were excluded, resulting in seven randomized clinical trials (2018–2025; total n = 350) evaluating spinal or peripheral mobilization/manipulation. No eligible randomized or sham-controlled trials meeting the prespecified criteria were identified before 2018. In chronic mechanical neck pain, cervical thrust manipulation improved cervical JPSE versus sham with large partial eta-squared effects (η2p = 0.23–0.36). Cervical mobilization improved left rotation JPSE (4.15 → 1.65° vs. 4.01→3.74°). In patellofemoral pain, lumbopelvic manipulation produced immediate reductions in knee JPSE at 60° (6.58 → 4.48° vs. 5.91 → 6.05°). Only one outcome/time-point was suitable for meta-analysis (knee JPSE at 60° flexion in patellofemoral pain; two trials), showing no statistically significant pooled effect (Hedges’ g = −0.21, 95% CI −1.36 to 0.94; I2 ≈ 83%). Remaining outcomes could not be pooled due to heterogeneity and incompatible reporting. Conclusions: Evidence from seven randomized trials indicates that articular manual therapy (mobilization and/or HVLA thrust manipulation) can improve quantitative proprioceptive outcomes immediately post-intervention, particularly JPSE in neck and patellofemoral pain; however, effects are condition- and outcome-specific, and confidence is limited by heterogeneity and the predominance of narrative synthesis with sparse poolable data. Future adequately powered trials should standardize proprioception protocols, include longer follow-up, and report data to enable robust meta-analysis. Full article
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23 pages, 959 KB  
Review
Therapeutic Patient Education in Adults with Chronic Lower Limb Musculoskeletal Pain: A Scoping Review
by Carla Vanti, Michael Bianchini, Alessio Mantineo, Francesco Ballardin and Paolo Pillastrini
Healthcare 2026, 14(3), 290; https://doi.org/10.3390/healthcare14030290 - 23 Jan 2026
Viewed by 1073
Abstract
Background: Conservative treatment of chronic musculoskeletal pain includes exercise, manual therapy, medications, physical agents/modalities, and Therapeutic Patient Education (TPE). Research on TPE has predominantly focused on spinal pain, so we do not know the extent and scope of clinical research in other [...] Read more.
Background: Conservative treatment of chronic musculoskeletal pain includes exercise, manual therapy, medications, physical agents/modalities, and Therapeutic Patient Education (TPE). Research on TPE has predominantly focused on spinal pain, so we do not know the extent and scope of clinical research in other areas, particularly lower extremities. This review aimed to map current research on this topic. Methods: We searched PubMed, PEDro, CINAHL, PsycINFO, and Cochrane Library up to 1 April 2024. We included RCTs on adults with chronic lower limb musculoskeletal pain, written in English, French, Spanish, or Italian. Results: Fifty-two records concerning knee osteoarthritis (n.33), hip and knee osteoarthritis (n.8), hip osteoarthritis (n.3), chronic knee pain (n.3), patellofemoral pain (n.3), and gluteal tendinopathy (n.2) were included. TPE was delivered through self-management, disease-specific information, pain education, and the management of physical activity, load, diet, stress, and sleep. Interventions were both individual- and group-based; delivery methods included in-person intervention, telephone/video calls, and web tools/apps. TPE combined with exercise seemed to be more effective than exercise alone, information/little education, or usual care. The effects of TPE as a stand-alone intervention appeared uncertain. Conclusions: There is considerable variability in TPE in terms of teaching topics, providers, administration methods, and dosage of interventions. Future studies should investigate the effects of TPE in young adult populations and in ankle conditions. They should also investigate the effects of TPE on pain intensity versus pain interference with activities, by deepening TPE effects on disability and quality of life. Full article
(This article belongs to the Special Issue Dysfunctions or Approaches of the Musculoskeletal System)
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13 pages, 1350 KB  
Article
Autologous Osteochondral Transplantation in Large Osteochondral Defects—A Follow-Up of 40 Patients After Talus Re-Surfacing
by Alice Wittig-Draenert, Martin Breitwieser, Patrick Marko, Wolfgang Hitzl and Jürgen Bruns
Diagnostics 2026, 16(2), 351; https://doi.org/10.3390/diagnostics16020351 - 21 Jan 2026
Viewed by 477
Abstract
Background/Objectives: Large osteochondral lesions of the talus (OLT) pose a major challenge because their size and depth often exceed the indications for bone marrow stimulation, and durable biological repair remains difficult to achieve. However, evidence for autologous osteochondral transplantation (AOT) in extensive [...] Read more.
Background/Objectives: Large osteochondral lesions of the talus (OLT) pose a major challenge because their size and depth often exceed the indications for bone marrow stimulation, and durable biological repair remains difficult to achieve. However, evidence for autologous osteochondral transplantation (AOT) in extensive talar defects is still limited. Methods: In this retrospective cohort, 40 consecutive patients ≥ 14 years with ICRS grade III–IV lesions of the talar dome were treated with AOT at a tertiary referral center. One to three overlapping cylindrical osteochondral grafts (mean diameter 0.9 cm) were harvested from non-weight-bearing regions of the ipsilateral patellofemoral groove using a water-cooled diamond trephine system and implanted press-fit into the talar dome. Donor sites were refilled with autologous iliac crest bone cylinders and hydroxyapatite substitute. Pain (Numeric Rating Scale, NRS) and function (AOFAS Ankle–Hindfoot Score) were recorded preoperatively and at 3, 6, 9, and 12 months, and changes over time were analyzed using generalized estimating equations. Results: Mean defect size was 137.4 ± 31.9 mm2, and 82.5% of lesions were ICRS grade III. NRS pain improved from 5.69 ± 2.52 preoperatively to 0.53 ± 0.98 at 12 months (p < 0.001). AOFAS score increased from 63.79 ± 2.55 to 97.36 ± 2.49 (p < 0.001). Age and graft location significantly influenced postoperative pain, whereas graft size and sex did not. No infections, graft failures, conversions to arthrodesis or arthroplasty, or clinically relevant donor-site symptoms occurred. Conclusions: Multi-plug AOT using a diamond trephine system provides substantial and durable pain relief and functional improvement in patients with large OLT, with low complication and donor-site morbidity rates. These findings support AOT as a joint-preserving option for extensive talar defects and justify further prospective, comparative studies with long-term follow-up. Full article
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16 pages, 1931 KB  
Article
Headless Screw Fixation Is Associated with Reduced Hardware Removal After Tibial Tubercle Osteotomy: A Retrospective Cohort Study
by Oguzhan Uslu and Ozkan Kose
J. Clin. Med. 2026, 15(1), 235; https://doi.org/10.3390/jcm15010235 - 28 Dec 2025
Viewed by 695
Abstract
Background/Objectives: Symptomatic hardware removal remains the most frequent cause of reoperation after tibial tubercle osteotomy (TTO), with removal rates reported as high as 49%. Headless compression screws have been proposed as a low-profile alternative to conventional screws to reduce hardware-related morbidity, yet [...] Read more.
Background/Objectives: Symptomatic hardware removal remains the most frequent cause of reoperation after tibial tubercle osteotomy (TTO), with removal rates reported as high as 49%. Headless compression screws have been proposed as a low-profile alternative to conventional screws to reduce hardware-related morbidity, yet no study has directly compared their use with headed screws in TTO for patellofemoral instability. This study aimed to compare complication rates and the frequency of hardware removal between headless and headed screw fixation in TTO. Methods: A retrospective review was conducted on 84 patients (94 knees) who underwent TTO between 2014 and 2024. Patients were divided into two groups based on the type of fixation used: headless screws (56 knees) and headed screws (38 knees). Demographic characteristics, perioperative variables, functional outcomes (Kujala, Lysholm, and Tegner scores), complications, and reoperation rates were compared with a minimum one-year follow-up. Results: No significant differences were found between the groups in terms of baseline demographic and clinical characteristics. Symptomatic implant removal occurred in 13.2% of the headed screw group and in none of the patients in the headless screw group (p = 0.001). Reoperation for any reason was significantly lower in the headless group (3.6% vs. 26.3%, p = 0.002). Functional outcomes were similar between groups. Post-hoc power analysis confirmed sufficient statistical power (98.8%) to detect differences in implant removal rates. Conclusion: Headless screw fixation in TTO was associated with significantly lower rates of hardware-related reoperations and painful implant removal, while achieving functional outcomes similar to those with headed screws. Headless screws may represent a preferable fixation method for reducing implant-related complications in TTO. Full article
(This article belongs to the Section Orthopedics)
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18 pages, 1320 KB  
Systematic Review
The Effectiveness of Photobiomodulation Therapy on Pain and Function in Patients with Patellofemoral Pain Syndrome—A Systematic Review and Meta-Analysis
by Mohamed Salaheldien Alayat, Roaa A. Sroge, Abdulaziz Awali, Ammar Fadil, Omair Belal Malibari, Raad Hatim Ajawi, Eyad Noor Wali, Suhail Hafiz and Sameer Yamani
J. Clin. Med. 2026, 15(1), 20; https://doi.org/10.3390/jcm15010020 - 19 Dec 2025
Viewed by 2646
Abstract
Objectives: The aim of this systematic review was to evaluate the effectiveness of photobiomodulation (PBM) on pain and function in individuals with Patellofemoral Pain Syndrome (PFPS). Methods: A systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. Search was [...] Read more.
Objectives: The aim of this systematic review was to evaluate the effectiveness of photobiomodulation (PBM) on pain and function in individuals with Patellofemoral Pain Syndrome (PFPS). Methods: A systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. Search was performed across PubMed/Midline, Scopus, Web of Science, EBSCO, ScienceDirect, Wiley Online Library, Springer, Cochrane CENTRAL, PEDro, ResearchGate, and Google Scholar from inception to January 2025. Randomized controlled trials (RCT) examining PBM in individuals with PFPS were included. Data extraction, risk-of-bias assessment (RoB 2), and quality of evidence evaluation (GRADE) were performed independently by multiple reviewers. Primary and secondary outcomes were pain and function, respectively. A random effect meta-analysis was performed to estimate the standardized mean difference (SMD) at 95% confidence interval (CI) and overall effect size. Results: Eight trials (340 participants) met the inclusion criteria. PBM significantly reduced pain compared with the control (SMD = −0.83; 95% CI −1.40 to −0.27). Functional outcomes demonstrated a significant improvement favoring PBM (SMD = 0.68; 95% CI 0.08 to 1.27), although substantial heterogeneity was present (I2 = 83%). RoB2 showed five high-risk studies. GRADE showed a very low quality of evidence due to study limitations, imprecision, and inconsistency which limit the confidence to the effect estimate. Conclusions: PBM, combined with exercise, provides improvements in pain and knee function in individuals with PFPS. While findings support PBM as an effective adjunct modality, standardized dosing protocols and larger, high-quality RCTs are needed to strengthen future clinical recommendations. Full article
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11 pages, 234 KB  
Article
Cross-Cultural Adaptation and Validation of the Norwich Patellar Instability (NPI) Score and the Banff Patellofemoral Instability Instrument (BPII) 2.0 in a Polish Pediatric Population
by Alicja Fąfara, Jarosław Feluś and Kinga Żmijewska-Jasińska
Children 2025, 12(12), 1708; https://doi.org/10.3390/children12121708 - 17 Dec 2025
Viewed by 515
Abstract
Introduction: Patellofemoral instability (PFI) is most prevalent in adolescents aged 10–17 years, yet disease-specific functional assessment tools validated for pediatric populations are limited. The Banff Patellofemoral Instability Instrument (BPII) 2.0 and the Norwich Patellar Instability (NPI) scores are disease-specific tools that have previously [...] Read more.
Introduction: Patellofemoral instability (PFI) is most prevalent in adolescents aged 10–17 years, yet disease-specific functional assessment tools validated for pediatric populations are limited. The Banff Patellofemoral Instability Instrument (BPII) 2.0 and the Norwich Patellar Instability (NPI) scores are disease-specific tools that have previously been validated in adults. The purpose of this study was to translate, culturally adapt, and validate the BPII 2.0 and NPI scores for Polish-speaking pediatric patients with PFI. Methods: The Polish versions of the BPII 2.0 and NPI were developed following Beaton’s cross-cultural adaptation guidelines. Patients aged 12–18 years with surgically treated recurrent patellofemoral joint instability completed the BPII 2.0, NPI, Anterior Knee Pain Scale (Kujala), Lysholm Knee Score, and Pedi-IKDC at a clinic visit and again 7–14 days later. The following psychometric properties were assessed: face validity, floor and ceiling effects, test–retest reliability (ICC), internal consistency (Cronbach’s α), and construct validity (Spearman Correlation Coefficients). Results: A total of 57 postoperative patients (19 males, 38 females; median age 16 years, range 12.25–18 years) participated 24–36 months after surgical stabilization. No floor or ceiling effects were observed. The test–retest reliability was excellent (ICC = 0.988 for BPII 2.0 (95% CI 0.977–0.994, p < 0.001); ICC = 0.997 for NPI (95% CI 0.995–0.998, p < 0.001)). Both instruments demonstrated excellent internal consistency (Cronbach’s α = 0.95 for BPII 2.0; α = 0.93 for NPI). The BPII 2.0 showed moderate to strong positive correlations with Lysholm (ρ = 0.69), Kujala (ρ = 0.69), and Pedi-IKDC (ρ = 0.57) and moderate negative correlation with NPI (ρ = −0.62), all of which were statistically significant (p < 0.001). Conclusion: The Polish versions of the BPII 2.0 and NPI scores demonstrated excellent reliability (ICC = 0.988 and 0.997, respectively), internal consistency (Cronbach’s α = 0.95 and 0.93, respectively), and construct validity in Polish-speaking adolescent patients with surgically treated recurrent patellofemoral instability. This is the first validation of the NPI in an exclusively pediatric population. These tools are suitable for clinical assessment and research in this specific population. Limitations include the postoperative-only cohort and absence of structural validity assessment. Full article
(This article belongs to the Special Issue Pediatric Orthopedic Injuries: Diagnosis and Treatment)
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Article
Medial Patellofemoral Ligament Reconstruction: Patient-Reported Outcome Measures Comparing Autograft and Allograft Tendons with or Without Tibial Tubercle Osteotomy
by Eli Beach, Daniel George, Claire Bolton and Shahram Shahrokhi
J. Clin. Med. 2025, 14(24), 8756; https://doi.org/10.3390/jcm14248756 - 10 Dec 2025
Viewed by 669
Abstract
Objectives: To compare patient-reported outcome measures (PROMS) as the primary outcome following medial patellofemoral ligament reconstruction (MPFLR) using autograft versus allograft tendon. Secondary objectives were to assess re-dislocation rates and evaluate the effect of concomitant tibial tubercle osteotomy (TTO) on PROMs. Methods: Eighty-eight [...] Read more.
Objectives: To compare patient-reported outcome measures (PROMS) as the primary outcome following medial patellofemoral ligament reconstruction (MPFLR) using autograft versus allograft tendon. Secondary objectives were to assess re-dislocation rates and evaluate the effect of concomitant tibial tubercle osteotomy (TTO) on PROMs. Methods: Eighty-eight patients from two fellowship-trained orthopaedic surgeons operating at a single institution between 2018 and 2023 were identified. Eligible patients, including those who had undergone an MPFLR with either autograft or allograft +/− TTO, were contacted to complete three validated surveys to quantify PROMS: the Kujala Anterior Knee Pain Score (Kujala), the Marx Activity Score (Marx), and the Norwich Patellar Instability Score (NPI). Exclusion criteria included musculoskeletal or collage disorders and incomplete PROMs. Re-dislocation rates and PROMS were compared between autograft and allograft groups. Independent samples t-tests were used, with p < 0.05 considered statistically significant. Results: A total of fifty-nine patients (46% male, average age 28.5 years old) representing 63 knees returned PROMs. All Kujala scores were similar between groups. Subgroup analysis revealed that patients who received an isolated MPFLR compared to those who received an MPFLR with TTO had lower NPI scores: 22.89% versus 30.21% (p < 0.001), respectively. Those who underwent isolated MPLFR with autograft compared to allograft had lower Marx scores: 7.40 versus 7.70 (p = 0.031), respectively. One patient who underwent an allograft experienced a recurrence of their patellar instability. Conclusions: There was a low recurrent patella dislocation rate following MPFLR and similar anterior knee pain scores in our study when comparing autograft with allograft. Full article
(This article belongs to the Section Orthopedics)
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