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396 Results Found

  • Article
  • Open Access
6 Citations
3,111 Views
14 Pages

Postmortem Muscle Protein Changes as a Tool for Monitoring Sahraoui Dromedary Meat Quality Characteristics

  • Hanane Smili,
  • Samira Becila,
  • Antonella della Malva,
  • Ayad Redjeb,
  • Marzia Albenzio,
  • Agostino Sevi,
  • Antonella Santillo,
  • Baaissa Babelhadj,
  • Abdelkader Adamou and
  • Rosaria Marino
  • + 1 author

2 March 2022

The effects of slaughter age (2 vs. 9 years) and postmortem time (6, 8, 10, 12, 24, 48 and 72 h) on the meat quality and protein changes of the longissimus lumborum muscles of the Algerian Sahraoui dromedary were investigated. Muscles of young dromed...

  • Article
  • Open Access
2,083 Views
15 Pages

Postmortem Changes in mRNA Expression and Tissue Morphology in Brain and Femoral Muscle Tissues of Rat

  • Sujin Choi,
  • Minju Jung,
  • Mingyoung Jeong,
  • Sohyeong Kim,
  • Dong Geon Lee,
  • Kwangmin Park,
  • Xianglan Xuan,
  • Heechul Park,
  • Dong Hyeok Kim and
  • Sunghyun Kim
  • + 3 authors

The postmortem interval (PMI), defined as the time elapsed between death and the discovery or examination of the body, is a crucial parameter in forensic science for estimating the time of death. There are many ways to measure the PMI, such as Henssg...

  • Article
  • Open Access
5 Citations
3,810 Views
15 Pages

The Influence of Eyelid Position and Environmental Conditions on the Corneal Changes in Early Postmortem Interval: A Prospective, Multicentric OCT Study

  • Matteo Nioi,
  • Pietro Emanuele Napoli,
  • Roberto Demontis,
  • Alberto Chighine,
  • Fabio De-Giorgio,
  • Simone Grassi,
  • Vincenzo Scorcia,
  • Maurizio Fossarello and
  • Ernesto d’Aloja

7 September 2022

In the current study, using portable optical coherence tomography, we evaluated 46 corneas of 23 individuals in a multicenter setting during the first 17 h after death. Twenty-three eyes were kept open, and twenty three were kept closed. Furthermore,...

  • Review
  • Open Access
3,571 Views
28 Pages

Isotopic investigations focused on determining the mobility and provenance of ancient human civilizations and sourcing of archeological artifacts continue to gain prominence in archeology. Most studies focus on the premise that the geographic variati...

  • Article
  • Open Access
19 Citations
4,594 Views
16 Pages

Postmortem Metabolomics: Strategies to Assess Time-Dependent Postmortem Changes of Diazepam, Nordiazepam, Morphine, Codeine, Mirtazapine and Citalopram

  • Lana Brockbals,
  • Yannick Wartmann,
  • Dylan Mantinieks,
  • Linda L. Glowacki,
  • Dimitri Gerostamoulos,
  • Thomas Kraemer and
  • Andrea E. Steuer

20 September 2021

Postmortem redistribution (PMR) can result in artificial drug concentration changes following death and complicate forensic case interpretation. Currently, no accurate methods for PMR prediction exist. Hence, alternative strategies were developed inv...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,771 Views
20 Pages

Morphological and Immunohistochemical Changes in Progressive Postmortem Autolysis of the Murine Brain

  • Francesca Parisi,
  • Sara Degl’Innocenti,
  • Çağla Aytaş,
  • Andrea Pirone and
  • Carlo Cantile

20 December 2024

In this time series study, the temporal sequences of postmortem changes in brains kept at different temperatures were investigated in different areas of mouse brains. Fixation of tissues kept at different storage temperatures (4 °C, 22 °C, 37 °C) was...

  • Article
  • Open Access
1 Citations
1,446 Views
14 Pages

Postmortem Temporal Changes in Liver and Spleen Stiffness: Evaluation with Shear Wave Elastography in a Rat Model

  • Ismail Taskent,
  • Selçuk Başer,
  • Bunyamin Ece,
  • Serbülent Kılıç,
  • Ugur Akpulat,
  • Irfan Cinar and
  • Nurtaç Sarıkaş

Background/Objectives: Postmortem changes in tissue stiffness and organ morphology are critical for forensic medicine and pathology. Shear wave elastography (SWE) has emerged as a non-invasive tool to assess tissue stiffness, yet its potential for po...

  • Article
  • Open Access
28 Citations
8,444 Views
16 Pages

The Quality Changes and Proteomic Analysis of Cattle Muscle Postmortem during Rigor Mortis

  • Zhenjiang Ding,
  • Qichao Wei,
  • Chunmei Liu,
  • Hong Zhang and
  • Feng Huang

13 January 2022

Rigor mortis occurs in a relatively early postmortem period and is a complex biochemical process in the conversion of muscle to meat. Understanding the quality changes and biomarkers during rigor mortis can provide a theoretical basis for maintaining...

  • Article
  • Open Access

Dynamic Metabolic Changes During Postmortem Aging of Yili Horsemeat Revealed by Untargeted Metabolomics

  • Xixi Yang,
  • Tongliang Wang,
  • Jingtao Gan,
  • Chen Meng,
  • Jingxuan Shen,
  • Zexu Li,
  • Xueyan Li,
  • Yaqi Zeng,
  • Wanlu Ren and
  • Jun Meng
  • + 1 author

5 February 2026

Postmortem aging is a crucial process for improving meat quality; however, the metabolic mechanisms underlying the postmortem maturation of Yili horsemeat remain unclear. In this study, untargeted metabolomics was employed to investigate the dynamic...

  • Article
  • Open Access
1 Citations
3,685 Views
13 Pages

Temporal and spatial epigenetic modifications in the brain occur during ontogenetic development, pathophysiological disorders, and aging. When epigenetic marks, such as histone methylations, in brain autopsies or biopsy samples are studied, it is cri...

  • Communication
  • Open Access
17 Citations
5,138 Views
12 Pages

Postmortem Ocular Findings in the Optical Coherence Tomography Era: A Proof of Concept Study Based on Six Forensic Cases

  • Matteo Nioi,
  • Pietro Emanuele Napoli,
  • Roberto Demontis,
  • Emanuela Locci,
  • Maurizio Fossarello and
  • Ernesto d’Aloja

28 February 2021

Postmortem analysis of the ocular globe is an important topic for forensic pathology and transplantology. Although crucial elements may be gathered from examining cadaveric eyes, the latter do not routinely undergo in-depth analysis. The paucity of q...

  • Article
  • Open Access
5 Citations
2,991 Views
13 Pages

A Biochemical and Histological Assessment of Postmortem Changes to the Eyes of Domestic Pigs: A Preliminary Study

  • Magdalena Palić,
  • Ivan-Conrado Šoštarić Zuckermann,
  • Petar Džaja,
  • Blanka Beer Ljubić and
  • Krešimir Severin

15 April 2024

The Postmortem Interval (PMI) is the time from the death of an animal to its discovery. From a veterinary forensic standpoint, an accurate estimation of the PMI is of particular importance, especially with the observed increase in deaths of domestic...

  • Article
  • Open Access
14 Citations
3,127 Views
15 Pages

4 March 2020

To explore the postmortem physiological mechanism of muscle, activity of adenosine monophosphate activated protein kinase (AMPK) as well as its role in energy metabolism of postmortem yaks were studied. In this experiment, we injected 5-amino-1-beta-...

  • Article
  • Open Access
3 Citations
2,378 Views
17 Pages

Changes in Meat of Hu Sheep during Postmortem Aging Based on ACQUITY UPLC I-Class Plus/VION IMS QTof

  • Jie Xu,
  • Qiang Wang,
  • Yimeng Wang,
  • Menghuan Bao,
  • Xiaomei Sun and
  • Yongjun Li

4 January 2024

Meat and meat products have a critical role in the human diet as important high-nutrient foods that are widely consumed worldwide. This study evaluated the effects of postmortem aging on Hu sheep’s meat quality in the longissimus dorsi (LD) mus...

  • Article
  • Open Access
10 Citations
2,366 Views
13 Pages

Liquid Chromatography–Mass Spectrometry-Based Metabolomics Reveals Dynamic Metabolite Changes during Early Postmortem Aging of Donkey Meat

  • Wenqiong Chai,
  • Liyuan Wang,
  • Tong Li,
  • Tianqi Wang,
  • Xinrui Wang,
  • Miao Yan,
  • Mingxia Zhu,
  • Jingrong Gao,
  • Changfa Wang and
  • Honglei Qu
  • + 1 author

9 May 2024

Background: Metabolic changes in donkey meat during the early postmortem period have not been previously reported. Methods: The LC–MS-based metabolomics technique was conducted to understand the metabolic profiles and identify the key metabolit...

  • Article
  • Open Access
13 Citations
2,838 Views
15 Pages

Changes in Microbial Communities Using Pigs as a Model for Postmortem Interval Estimation

  • Fan Yang,
  • Xiangyan Zhang,
  • Sheng Hu,
  • Hao Nie,
  • Peng Gui,
  • Zengtao Zhong,
  • Yadong Guo and
  • Xingchun Zhao

Microbial communities can undergo significant successional changes during decay and decomposition, potentially providing valuable insights for determining the postmortem interval (PMI). The microbiota produce various gases that cause cadaver bloating...

  • Review
  • Open Access
30 Citations
18,579 Views
12 Pages

19 February 2022

There are several methodologies available to estimate time since death based on different changes that a corpse undergoes after death. However, these methods are imprecise due to the decomposition process being affected by several factors, principall...

  • Article
  • Open Access
15 Citations
3,445 Views
11 Pages

27 May 2022

Background: The nucleus accumbens (NAc) is a key brain structure mediating the rewarding effect of alcohol and drug abuse. Chronic alcohol consumption may alter RNA methylome (or epitranscriptome) in the NAc, leading to altered gene expression and th...

  • Article
  • Open Access
5 Citations
3,156 Views
15 Pages

Postmortem Electrical Conductivity Changes of Dicentrarchus labrax Skeletal Muscle: Root Mean Square (RMS) Parameter in Estimating Time since Death

  • Jessica Maria Abbate,
  • Gabriele Grifò,
  • Fabiano Capparucci,
  • Francesca Arfuso,
  • Serena Savoca,
  • Luca Cicero,
  • Giancarlo Consolo and
  • Giovanni Lanteri

20 April 2022

Electric impedance spectroscopy techniques have been widely employed to study basic biological processes, and recently explored to estimate postmortem interval (PMI). However, the most-relevant parameter to approximate PMI has not been recognized so...

  • Article
  • Open Access
25 Citations
4,354 Views
18 Pages

30 March 2021

In this paper, the protein changes during aging and the differences in the myofibrillar protein fraction at 1 h postmortem of pale, soft and exudative (PSE), and red, firm and non-exudative (RFN) pork longissimus thoracis (LT) were comparatively stud...

  • Systematic Review
  • Open Access
1,290 Views
13 Pages

20 August 2025

Background: The phenomenon of pink teeth represents a notable observation in forensic science, although its interpretation remains complex and not directly attributable to a specific cause of death. Methods: This systematic review provides an updated...

  • Article
  • Open Access
1 Citations
893 Views
15 Pages

Evaluation of RNA Stability and Molecular Biomarkers for Post-Mortem Interval Estimation in Rat Organs

  • Minju Jung,
  • Sujin Choi,
  • Mingyoung Jeong,
  • Sohyeong Kim,
  • Dong Geon Lee,
  • Kwangmin Park,
  • Xianglan Xuan,
  • Yujin Park,
  • Heechul Park and
  • Sunghyun Kim
  • + 4 authors

20 November 2025

Post-mortem interval (PMI) analysis plays a crucial role in forensic investigations, providing essential insights into the time since death. This study examined histological changes and ribonucleic acid (RNA) quantification across major organs to ide...

  • Article
  • Open Access
1 Citations
2,216 Views
15 Pages

16 December 2024

The aging of lithium-ion cells critically affects their lifetime, safety, and performance, particularly due to electrode and electrolyte degradation. This study introduced a novel combined-measurement cell-integrating operando dilatometry and operand...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,103 Views
17 Pages

Study of the Quality and Nutritional Value of Alosa sapidissima in the Postmortem Process

  • Le Li,
  • Haojun Zhu,
  • Xiangyu Yi,
  • Zhijuan Nie,
  • Yao Zheng,
  • Xiwei Yang,
  • Pao Xu,
  • Yaqing Yu and
  • Gangchun Xu

24 October 2022

The American shad (Alosa sapidissima) is an important freshwater food fish, yet little is known about its postmortem quality. We sampled the meat of American shad and tracked the changes in color, pH, shear stress, cooking loss and total volatile bas...

  • Article
  • Open Access
4 Citations
2,253 Views
22 Pages

Proteomic Characterization of Changes in Mouse Brain Cortex Protein Expression at Different Post-Mortem Intervals: A Preliminary Study for Forensic Biomarker Identification

  • Martina Bonelli,
  • Fabrizio Di Giuseppe,
  • Nicola Tupone,
  • Vimal Di Virgilio,
  • Antonio Maria Catena,
  • Marcello Locatelli,
  • Giuliano Ascani,
  • Gianluigi Giammaria,
  • Renata Ciccarelli and
  • Stefania Angelucci
  • + 1 author

10 August 2024

Accuracy in the evaluation of death-induced tissue degradation for thanato-chronological purposes is strictly dependent on the condition of the biological source as well as on the precision of post-mortem interval (PMI) estimation. Thus, the optimiza...

  • Article
  • Open Access
28 Citations
5,931 Views
12 Pages

Stress Associated with Simulated Transport, Changes Serum Biochemistry, Postmortem Muscle Metabolism, and Meat Quality of Broilers

  • Aijuan Zheng,
  • Shumei Lin,
  • Shoaib Ahmed Pirzado,
  • Zhimin Chen,
  • Wenhuan Chang,
  • Huiyi Cai and
  • Guohua Liu

18 August 2020

Many factors contribute to the stress of transporting broilers from the farm to the processing plant. Using a motion simulation machine, a total of 144 male broilers were employed to determine the effect of motion, vibration, and feed withdrawal duri...

  • Article
  • Open Access
10 Citations
2,898 Views
16 Pages

27 December 2022

Alterations of apoptosis have notable influences on flesh quality, but the mechanism is still unclear. Thus, apoptotic behaviors and related triggering mechanisms need to be explored. Fish muscle was prepared and stored at 4 °C for 0, 24, 48, 72,...

  • Article
  • Open Access
5 Citations
3,850 Views
15 Pages

Post-Mortem Analysis of Neuropathological Changes in Human Tinnitus

  • Faris Almasabi,
  • Faisal Alosaimi,
  • Minerva Corrales-Terrón,
  • Anouk Wolters,
  • Dario Strikwerda,
  • Jasper V. Smit,
  • Yasin Temel,
  • Marcus L. F. Janssen and
  • Ali Jahanshahi

1 August 2022

Tinnitus is the phantom perception of a sound, often accompanied by increased anxiety and depressive symptoms. Degenerative or inflammatory processes, as well as changes in monoaminergic systems, have been suggested as potential underlying mechanisms...

  • Article
  • Open Access
5 Citations
2,942 Views
13 Pages

Effects of Farm Management Practices and Transport Time on Post-Mortem Changes of Longissimus lumborum Muscle Proteins in Suckling Goat Kids

  • Tomás Francisco Martínez,
  • María Jesús Alcalde,
  • María Isabel Sáez and
  • María Dolores Suárez

15 July 2020

The combined effect of farm management practices, transport time, and ageing time on the electrophoretic changes of sarcoplasmic (SPP) and myofibrillar (MFP) protein fractions of goat kids was studied. A total of 64 suckling goat kids were withdrawn...

  • Article
  • Open Access
15 Citations
3,769 Views
14 Pages

Proteomic Changes in Sarcoplasmic and Myofibrillar Proteins Associated with Color Stability of Ovine Muscle during Post-Mortem Storage

  • Xiaoguang Gao,
  • Dandan Zhao,
  • Lin Wang,
  • Yue Cui,
  • Shijie Wang,
  • Meng Lv,
  • Fangbo Zang and
  • Ruitong Dai

3 December 2021

The objective of this study was to investigate the proteomic characteristics for the sarcoplasmic and myofibrillar proteomes of M. longissimus lumborum (LL) and M. psoasmajor (PM) from Small-tailed Han Sheep. During post-mortem storage periods (1, 3,...

  • Review
  • Open Access
2 Citations
3,440 Views
23 Pages

19 September 2024

In vivo proton (1H) magnetic resonance spectroscopy (MRS) is a powerful non-invasive method that can measure Alzheimer’s disease (AD)-related neuropathological alterations at the molecular level. AD biomarkers include amyloid-beta (Aβ) pla...

  • Article
  • Open Access
10 Citations
3,672 Views
16 Pages

19 February 2023

The radiographic, ultrasonographic, and scintigraphic findings of horses with thoracolumbosacral pain have been previously reported. In this study, the computed tomographic appearance of anatomical variations and pathological changes of the equine ca...

  • Article
  • Open Access
3 Citations
2,130 Views
13 Pages

Study of Root Transparency in Different Postmortem Intervals Using Scanning Electron Microscopy

  • Elodie Marchand,
  • Benoit Bertrand,
  • Valéry Hedouin,
  • Xavier Demondion and
  • Anne Becart

30 August 2023

In the fields of forensics, the identification of human remains is a recurrent problem. The estimated age at death is one of the copious criteria to be evaluated. In adult teeth, the height of the root dentin transparency is used to estimate age. How...

  • Article
  • Open Access
16 Citations
4,271 Views
19 Pages

Proteomics Unveils Post-Mortem Changes in Beef Muscle Proteins and Provides Insight into Variations in Meat Quality Traits of Crossbred Young Steers and Heifers Raised in Feedlot

  • Mariane Severino,
  • Mohammed Gagaoua,
  • Welder Baldassini,
  • Richard Ribeiro,
  • Juliana Torrecilhas,
  • Guilherme Pereira,
  • Rogério Curi,
  • Luis Artur Chardulo,
  • Pedro Padilha and
  • Otávio Machado Neto

14 October 2022

Proteomics has been widely used to study muscle biology and meat quality traits from different species including beef. Beef proteomics studies allow a better understanding of the biological processes related to meat quality trait determination. This...

  • Article
  • Open Access
16 Citations
3,175 Views
14 Pages

Metabolites Analysis on Water-Holding Capacity in Beef Longissimus lumborum Muscle during Postmortem Aging

  • Huixin Zuo,
  • Pengsen Wang,
  • Zonglin Guo,
  • Xin Luo,
  • Yimin Zhang and
  • Yanwei Mao

13 March 2022

Currently, the metabolomic research on water-holding capacity (WHC) of beef during postmortem aging is still insufficient. In this paper, the kit method was adopted for energy metabolites testing, the ultra-high-performance liquid chromatography (UHP...

  • Communication
  • Open Access
1 Citations
3,798 Views
8 Pages

Cell Mechanisms of Post-Mortem Excitability of Skeletal Muscle

  • H. Stigter,
  • T. Krap and
  • W. L. J. M. Duijst

Background/Objectives: The excitability of skeletal muscle is a less-known post-mortem supravital phenomenon in human bodies, and it can be used to estimate the post-mortem interval. We conducted a field study in the Netherlands to investigate the ap...

  • Article
  • Open Access
9 Citations
5,834 Views
13 Pages

Estimation of Early Postmortem Interval from Long Noncoding RNA Gene Expression in the Incised Cutaneous Wound: An Experimental Study

  • Mona M. Ali,
  • Samah F. Ibrahim,
  • Noha M. Elrewieny,
  • Aya M. Elyamany,
  • Wagdy K. B. Khalil,
  • Aziza B. Shalby and
  • Sarah A. Khater

14 November 2022

The assessment of alteration of postmortem RNA expression has forensic significance in estimating postmortem interval. To evaluate wound healing progression and the effect of different postmortem intervals, histopathological changes, immunohistochemi...

  • Article
  • Open Access
7 Citations
4,175 Views
16 Pages

The Effects of Postmortem Time on Muscle Trout Biochemical Composition and Structure

  • Arno Germond,
  • Annie Vénien,
  • Christine Ravel,
  • Brayan Castulovich,
  • Jacques Rouel,
  • Morgane Hutin,
  • Sara Mezelli,
  • Sandy Lefin,
  • Pierre-Sylvain Mirade and
  • Thierry Astruc

11 May 2023

Fish industry operators have to process fish that arrive at various postmortem times. Postmortem time constrains processing and impacts product quality, safety, and economic value. The objective identification of biomarkers is desirable to predict th...

  • Article
  • Open Access
4 Citations
5,726 Views
7 Pages

The Pink Teeth Phenomenon in Dogs and a Cat

  • Adam W. Stern,
  • AnnMarie Clark,
  • Jason H. Byrd,
  • Katrina M. Leser and
  • Haley Russo

12 October 2022

The observance of pink teeth during the postmortem period in humans is known as the pink teeth phenomenon. In contrast, postmortem pink discoloration of teeth is rarely reported in veterinary medicine. We examined the teeth of nine dogs and a cat pos...

  • Article
  • Open Access
11 Citations
3,558 Views
15 Pages

In Vitro Animal Model for Estimating the Time since Death with Attention to Early Postmortem Stage

  • Michal Szeremeta,
  • Paulina Samczuk,
  • Karolina Pietrowska,
  • Tomasz Kowalczyk,
  • Katarzyna Przeslaw,
  • Julia Sieminska,
  • Adam Kretowski,
  • Anna Niemcunowicz-Janica and
  • Michal Ciborowski

23 December 2022

Estimating the postmortem interval (PMI) has remained the subject of investigations in forensic medicine for many years. Every kind of death results in changes in metabolites in body tissues and fluids due to lack of oxygen, altered circulation, enzy...

  • Article
  • Open Access
1,301 Views
17 Pages

Objectives: Determination of the postmortem interval (PMI) remains a critical challenge in forensic science. Intervertebral discs, due to their structural resilience, hold promise as a reliable tissue for PMI estimation; however, studies focusing on...

  • Article
  • Open Access
4 Citations
4,022 Views
15 Pages

11-Nor-9-Carboxy Tetrahydrocannabinol Distribution in Fluid from the Chest Cavity in Cannabis-Related Post-Mortem Cases

  • Torki A. Zughaibi,
  • Hassan Alharbi,
  • Adel Al-Saadi,
  • Abdulnasser E. Alzahrani and
  • Ahmed I. Al-Asmari

29 August 2023

In this study, the presence of 11-nor-Δ9-carboxy tetrahydrocannabinol (THC-COOH) in postmortem fluid obtained from the chest cavity (FCC) of postmortem cases collected from drug-related fatalities or criminal-related deaths in Jeddah, Saudi Ara...

  • Article
  • Open Access
8 Citations
3,019 Views
15 Pages

New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19—A Large Postmortem and Clinical Analysis

  • Fabian Heinrich,
  • Kevin Roedl,
  • Dominik Jarczak,
  • Hanna-Lisa Goebels,
  • Axel Heinemann,
  • Ulrich Schäfer,
  • Frank Ludwig,
  • Martin Bachmann,
  • Berthold Bein and
  • Dominic Wichmann
  • + 10 authors

14 April 2022

Critically ill COVID-19 patients are at high risk for venous thromboembolism (VTE), namely deep vein thrombosis (DVT) and/or pulmonary embolism (PE), and death. The optimal anticoagulation strategy in critically ill patients with COVID-19 remains unk...

  • Article
  • Open Access
2 Citations
2,433 Views
14 Pages

Polymeric Carbon Nitrides for Photoelectrochemical Applications: Ring Opening-Induced Degradation

  • Florentina Iuliana Maxim,
  • Eugenia Tanasa,
  • Bogdan Mitrea,
  • Cornelia Diac,
  • Tomáš Skála,
  • Liviu Cristian Tanase,
  • Cătălin Ianăși,
  • Adrian Ciocanea,
  • Stefan Antohe and
  • Serban N. Stamatin
  • + 2 authors

31 March 2023

Active and stable materials that utilize solar radiation for promoting different reactions are critical for emerging technologies. Two of the most common polymeric carbon nitrides were prepared by the thermal polycondensation of melamine. The scope o...

  • Opinion
  • Open Access
4 Citations
5,011 Views
11 Pages

Illustrated Neuropathologic Diagnosis of Alzheimer’s Disease

  • Nicholas Doher,
  • Vahid Davoudi,
  • Shino Magaki,
  • Ryan A. Townley,
  • Mohammad Haeri and
  • Harry V. Vinters

12 July 2023

As of 2022, the prevalence of Alzheimer’s disease (AD) among individuals aged 65 and older is estimated to be 6.2 million in the United States. This figure is predicted to grow to 13.8 million by 2060. An accurate assessment of neuropathologic...

  • Article
  • Open Access
4 Citations
2,429 Views
13 Pages

Sampling Method Affects HR-MAS NMR Spectra of Healthy Caprine Brain Biopsies

  • Annakatrin Häni,
  • Gaëlle Diserens,
  • Anna Oevermann,
  • Peter Vermathen and
  • Christina Precht

6 January 2021

The metabolic profiling of tissue biopsies using high-resolution–magic angle spinning (HR-MAS) 1H nuclear magnetic resonance (NMR) spectroscopy may be influenced by experimental factors such as the sampling method. Therefore, we compared the ef...

  • Article
  • Open Access
11 Citations
4,116 Views
11 Pages

Postmortem Metabolomics Reveal Acylcarnitines as Potential Biomarkers for Fatal Oxycodone-Related Intoxication

  • Albert Elmsjö,
  • Carl Söderberg,
  • Gerd Jakobsson,
  • Henrik Green and
  • Robert Kronstrand

25 January 2022

Postmortem metabolomics has recently been suggested as a potential tool for discovering new biological markers able to assist in death investigations. Interpretation of oxycodone concentrations in postmortem cases is complicated, as oxycodone toleran...

  • Article
  • Open Access
2 Citations
2,530 Views
14 Pages

Muscle Proteins, Technological Properties, and Free Amino Acids of Epaxial Muscle Collected from Asian Seabass (Lates calcarifer) at Different Postmortem Durations

  • Yuwares Malila,
  • Danai Charoensuk,
  • Yanee Srimarut,
  • Sunitta Saensa-ard,
  • Nalinrat Petpiroon,
  • Chanikarn Kunyanee,
  • Wachiraya Rattanawongsa,
  • Rattaporn Saenmuangchin,
  • Annop Klamchuen and
  • Sasitorn Aueviriyavit
  • + 1 author

1 October 2024

The aim of this study was to compare the changes in the epaxial muscle proteins of Asian seabass at two different postmortem durations. The epaxial muscles of Asian seabass were collected 1 h or 24 h postmortem (PM). Whole, ungutted fish were stored...

  • Article
  • Open Access
3 Citations
3,994 Views
20 Pages

4 August 2023

Post-mortem ovarian tissue degradation from handling effects, such as delays in preservation, can lead to inaccurate reproductive assessments. Therefore, it is important to understand the differences between handling effects and natural ovarian atres...

  • Article
  • Open Access
2 Citations
2,609 Views
18 Pages

A Quantitative and Comparative Study of Heroin-Related Metabolites in Different Postmortem Fluids and Tissues

  • Torki A. Zughaibi,
  • Ziad Assiri,
  • Ahmed Mirza,
  • Hassan Alharbi,
  • Abdulnasser E. Alzahrani,
  • Sultan A. Alahmadi,
  • Faiz Alsolami,
  • Adel Al-Saadi,
  • Mohamed Almoustady and
  • Ahmed I. Al-Asmari
  • + 2 authors

20 March 2025

This study assessed and compared the postmortem concentrations of 6-monoacetylmorphine [6-MAM] and 6-acetylcodeine [6-AC], morphine, and codeine in various tissues and fluids from 52 postmortem cases related to heroin use. Samples were received at th...

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