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Keywords = pseudoxanthoma elasticum-like papillary dermal elastolysis

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6 pages, 1756 KB  
Clinicopathological Challenge
Skin-Colored Papules on the Neck of a Postmenopausal Woman: A Diagnostic Challenge
by Jason El Jalkh, Pia Maria Obeid, Dorra Guermazi, Aya Soubra and Elie Saliba
Dermatopathology 2025, 12(2), 15; https://doi.org/10.3390/dermatopathology12020015 - 14 May 2025
Viewed by 877
Abstract
A 64-year-old patient presented for management of symptomatic skin-colored papules symmetrically distributed over the lateral neck over the past two years, which failed to improve on multiple topical corticosteroids, antifungal creams, and topical calcineurin inhibitor. Histopathologic examination showed a regular epidermis with increased [...] Read more.
A 64-year-old patient presented for management of symptomatic skin-colored papules symmetrically distributed over the lateral neck over the past two years, which failed to improve on multiple topical corticosteroids, antifungal creams, and topical calcineurin inhibitor. Histopathologic examination showed a regular epidermis with increased melanophages in the papillary dermis, without vacuolar degeneration of the basement membrane. Verhoeff Van Gieson stain highlighted a band-like zone of attenuated elastic fibers in the papillary dermis, while Von Kossa stain was negative for calcified fibers. PAS staining was negative for fungal organisms and Alcian blue showed no increase in dermal mucin. Full article
(This article belongs to the Section Clinico-Pathological Correlation in Dermatopathology)
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