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Keywords = range extended target detection

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26 pages, 5444 KB  
Article
ADG-YOLO: A Lightweight and Efficient Framework for Real-Time UAV Target Detection and Ranging
by Hongyu Wang, Zheng Dang, Mingzhu Cui, Hanqi Shi, Yifeng Qu, Hongyuan Ye, Jingtao Zhao and Duosheng Wu
Drones 2025, 9(10), 707; https://doi.org/10.3390/drones9100707 (registering DOI) - 13 Oct 2025
Abstract
The rapid evolution of UAV technology has increased the demand for lightweight airborne perception systems. This study introduces ADG-YOLO, an optimized model for real-time target detection and ranging on UAV platforms. Building on YOLOv11n, we integrate C3Ghost modules for efficient feature fusion and [...] Read more.
The rapid evolution of UAV technology has increased the demand for lightweight airborne perception systems. This study introduces ADG-YOLO, an optimized model for real-time target detection and ranging on UAV platforms. Building on YOLOv11n, we integrate C3Ghost modules for efficient feature fusion and ADown layers for detail-preserving downsampling, reducing the model’s parameters to 1.77 M and computation to 5.7 GFLOPs. The Extended Kalman Filter (EKF) tracking improves positional stability in dynamic environments. Monocular ranging is achieved using similarity triangle theory with known target widths. Evaluations on a custom dataset, consisting of 5343 images from three drone types in complex environments, show that ADG-YOLO achieves 98.4% mAP0.5 and 85.2% mAP0.5:0.95 at 27 FPS when deployed on Lubancat4 edge devices. Distance measurement tests indicate an average error of 4.18% in the 0.5–5 m range for the DJI NEO model, and an average error of 2.40% in the 2–50 m range for the DJI 3TD model. These results suggest that the proposed model provides a practical trade-off between detection accuracy and computational efficiency for resource-constrained UAV applications. Full article
9 pages, 1855 KB  
Communication
Range Enhancement of a 60 GHz FMCW Heart Rate Radar Using Fabry–Perot Cavity Antenna
by Jae-Min Jeong, Hyun-Se Bae, Hong Ju Lee and Jae-Gon Lee
Electronics 2025, 14(20), 4014; https://doi.org/10.3390/electronics14204014 (registering DOI) - 13 Oct 2025
Abstract
This paper presents a bistatic 60 GHz frequency-modulated continuous-wave (FMCW) radar system for non-contact heart rate monitoring, utilizing high-gain Fabry–Perot cavity (FPC) antennas at both the transmitter and receiver. Each FPC antenna integrates a partially reflective surface (PRS) and a metallic ground plane [...] Read more.
This paper presents a bistatic 60 GHz frequency-modulated continuous-wave (FMCW) radar system for non-contact heart rate monitoring, utilizing high-gain Fabry–Perot cavity (FPC) antennas at both the transmitter and receiver. Each FPC antenna integrates a partially reflective surface (PRS) and a metallic ground plane to form a resonant cavity. Compared to conventional patch arrays of the same aperture, the FPC antenna improves the antenna gain from 4.1 dBi to 8.1 dBi at the transmitter and from 3.9 dBi to 7.8 dBi at the receiver, resulting in an overall link budget enhancement of approximately 7.9 dB. This dual high-gain configuration theoretically increases the maximum detection range by a factor of 2.48. The proposed radar system was implemented and experimentally validated under indoor conditions using both calibration targets and human participants. Active measurement results confirm that the bistatic radar equipped with FPC antennas extends the reliable heart rate detection distance by approximately 2.27 times compared to a conventional system, closely matching the theoretical prediction. These results confirm the practicality and effectiveness of FPC antennas in extending both the range and reliability of millimeter-wave vital sign detection systems. Full article
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12 pages, 5483 KB  
Communication
An Antenna Array with Wide Flat-Top Beam and Low Sidelobes for Aerial Target Detection
by Liangzhou Li, Yan Dong, Xiao Cai and Jingqian Tian
Sensors 2025, 25(19), 5991; https://doi.org/10.3390/s25195991 - 28 Sep 2025
Viewed by 480
Abstract
The misuse of drone technology poses significant risks to public and personal safety, emphasizing the need for accurate and efficient aerial target detection to prevent detection failures due to randomly distributed airborne targets and mitigate interference from undesired directions. Unlike conventional beam-synthesis techniques [...] Read more.
The misuse of drone technology poses significant risks to public and personal safety, emphasizing the need for accurate and efficient aerial target detection to prevent detection failures due to randomly distributed airborne targets and mitigate interference from undesired directions. Unlike conventional beam-synthesis techniques that often require either a large number of array elements or iterative numerical optimization, the proposed method analytically derives the excitation distribution by solving a newly formulated weighted-constraint problem, thereby fully accounting for mutual coupling between elements and ensuring both computational efficiency and design accuracy. In this communication, a 10 × 4 planar microstrip antenna array with a wide flat-top beam and low sidelobe is designed based on the extended method of maximum power transmission efficiency. The optimized distribution of excitations for the antenna array, which achieves a shaped beam with uniform gain over the desired angular range while suppressing sidelobe levels (SLLs) outside the shaped region, is derived by analytically solving a newly formulated weighted constraint problem. To reduce the number of antenna elements and enhance radiation characteristics, the inter-element spacings in the E-plane and H-plane are set to 0.55 λ0 and 0.75 λ0, where λ0 is the free-space wavelength at 3.5 GHz. Measurement results indicate that the flat-top beam in the E-plane has a wide half-power beamwidth (HPBW) of 51.2° and a low SLL of −30.1 dB, while the beam in the H-plane has a narrow HPBW of 20.1° and a low SLL of −30.5 dB, thereby demonstrating its capability in aerial target detection and airborne tracking applications. Full article
(This article belongs to the Special Issue Recent Trends and Developments in Antennas: Second Edition)
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15 pages, 1544 KB  
Article
Receiver Location Optimization for Heterogeneous S-Band Marine Transmitters in Passive Multistatic Radar Networks via NSGA-II
by Xinpeng Li, Pengfei He, Jie Song and Zhongxun Wang
Sensors 2025, 25(18), 5861; https://doi.org/10.3390/s25185861 - 19 Sep 2025
Viewed by 343
Abstract
Comprehensive maritime domain awareness is crucial for navigation safety, traffic management, and security surveillance. In the context of an increasingly complex modern electromagnetic environment, the disadvantages of traditional active single-station radars, such as their high cost and susceptibility to interference, have started to [...] Read more.
Comprehensive maritime domain awareness is crucial for navigation safety, traffic management, and security surveillance. In the context of an increasingly complex modern electromagnetic environment, the disadvantages of traditional active single-station radars, such as their high cost and susceptibility to interference, have started to surface. Due to their unique advantages, such as low cost, environmental sustainability (by reusing existing signals), and resilience in congested spectral environments, non-cooperative passive multistatic radar (PMR) systems have gained significant interest in maritime monitoring. This paper presents the research background of non-cooperative passive multistatic radar systems, performs a fundamental analysis of the detection performance of multistatic radar systems, and suggests an optimization method for the transceiver configuration of non-cooperative passive multistatic radar systems based on geometric coverage theory and a signal-to-noise ratio model. A multi-objective optimization model is developed, considering both detection coverage and positioning error, and is solved using the Non-dominated Sorting Genetic Algorithm II (NSGA-II). The optimization aims to find the optimal receiver location relative to a fixed configuration of four transmitters, representing common maritime traffic patterns. According to the simulation results, the multi-target genetic algorithm can be utilized to optimize the receiver position under the S-band radar settings used in this work. Compared to a random placement baseline, this can reduce the positioning error by about 8.9% and extend the detection range by about 15.8%. Furthermore, for the specific four-transmitter configuration and S-band radar parameters considered in this study, it is found that the best detection performance is more likely to be obtained when the receiver is placed within 15 km of the transmitters’ geometric center. Full article
(This article belongs to the Section Radar Sensors)
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15 pages, 4767 KB  
Article
First Report of the Yezo Virus Isolates Detection in Russia
by Mikhail Kartashov, Kirill Svirin, Alina Zheleznova, Alexey Yanshin, Nikita Radchenko, Valentina Kurushina, Tatyana Tregubchak, Lada Maksimenko, Mariya Sivay, Vladimir Ternovoi, Alexander Agafonov and Anastasia Gladysheva
Viruses 2025, 17(8), 1125; https://doi.org/10.3390/v17081125 - 15 Aug 2025
Viewed by 1018
Abstract
The recent discovery of the Yezo virus (YEZV) in Japan and China has raised particular concern due to its potential to cause human diseases ranging from mild febrile illnesses to severe neurological disorders. We report, for the first time, the detection of five [...] Read more.
The recent discovery of the Yezo virus (YEZV) in Japan and China has raised particular concern due to its potential to cause human diseases ranging from mild febrile illnesses to severe neurological disorders. We report, for the first time, the detection of five YEZV isolates in I. persulcatus ticks from three regions of Russia. The analysis was performed using 5318 ticks of two Ixodes genus collected in 2024 from 23 regions of Russia. The minimum infection rate of YEZV in Russia among I. persulcatus ticks was 0.12% (95% CI: 0.05–0.28). The westernmost and northernmost YEZV detection points have been recorded. YEZV isolates circulating in Russia are genetically diverse. Protein domains of Russian YEZV isolates’ genomes were characterized using HMMER, AlphaFold 3, and InterProScan. The YEZV nucleoprotein (N) of Russian isolates has a racket-shaped structure with “head” and “stalk” domains similar to those of Orthonairovirus haemorrhagiae. The Lys261–Arg261 substitution in the YEZV N Chita 2024-1 isolate occurs in the α11 structure in the region of interaction with viral RNA. Our results show that the distribution area of YEZV is much wider than previously known, provide new data on complete YEZV genomes, extend our structural insight into YEZV N, and suggest a potential target for antiviral drug development to treat YEZV infection. Full article
(This article belongs to the Special Issue Tick-Borne Viruses: Transmission and Surveillance, 2nd Edition)
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11 pages, 5939 KB  
Article
Low-Cost Phased Array with Enhanced Gain at the Largest Deflection Angle
by Haotian Wen, Hansheng Su, Yan Wen, Xin Ma and Deshuang Zhao
Electronics 2025, 14(15), 3111; https://doi.org/10.3390/electronics14153111 - 5 Aug 2025
Cited by 1 | Viewed by 754
Abstract
This paper presents a low-cost 1-bit phased array operating at 17 GHz (Ku band) with an enhanced scanning gain at the largest deflection angle to extend the beam coverage for ground target detection. The phased array is designed using 16 (2 × 8) [...] Read more.
This paper presents a low-cost 1-bit phased array operating at 17 GHz (Ku band) with an enhanced scanning gain at the largest deflection angle to extend the beam coverage for ground target detection. The phased array is designed using 16 (2 × 8) radiation-phase reconfigurable dipoles and a fixed-phase feeding network, achieving 1-bit beam steering via a direct current (DC) bias voltage of ±5 V. Measurement results demonstrate a peak gain of 9.2 dBi at a deflection angle of ±37°, with a 3 dB beamwidth of 94° across the scanning plane. Compared with conventional phased array radars with equivalent peak gains, the proposed design achieves a 16% increase in the detection range at the largest deflection angle. Full article
(This article belongs to the Section Microwave and Wireless Communications)
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32 pages, 18111 KB  
Article
Across-Beam Signal Integration Approach with Ubiquitous Digital Array Radar for High-Speed Target Detection
by Le Wang, Haihong Tao, Aodi Yang, Fusen Yang, Xiaoyu Xu, Huihui Ma and Jia Su
Remote Sens. 2025, 17(15), 2597; https://doi.org/10.3390/rs17152597 - 25 Jul 2025
Viewed by 479
Abstract
Ubiquitous digital array radar (UDAR) extends the integration time of moving targets by deploying a wide transmitting beam and multiple narrow receiving beams to cover the entire observed airspace. By exchanging time for energy, it effectively improves the detection ability for weak targets. [...] Read more.
Ubiquitous digital array radar (UDAR) extends the integration time of moving targets by deploying a wide transmitting beam and multiple narrow receiving beams to cover the entire observed airspace. By exchanging time for energy, it effectively improves the detection ability for weak targets. Nevertheless, target motion introduces severe across-range unit (ARU), across-Doppler unit (ADU), and across-beam unit (ABU) effects, dispersing target energy across the range–Doppler-beam space. This paper proposes a beam domain angle rotation compensation and keystone-matched filtering (BARC-KTMF) algorithm to address the “three-crossing” challenge. This algorithm first corrects ABU by rotating beam–domain coordinates to align scattered energy into the final beam unit, reshaping the signal distribution pattern. Then, the KTMF method is utilized to focus target energy in the time-frequency domain. Furthermore, a special spatial windowing technique is developed to improve computational efficiency through parallel block processing. Simulation results show that the proposed approach achieves an excellent signal-to-noise ratio (SNR) gain over the typical single-beam and multi-beam long-time coherent integration (LTCI) methods under low SNR conditions. Additionally, the presented algorithm also has the capability of coarse estimation for the target incident angle. This work extends the LTCI technique to the beam domain, offering a robust framework for high-speed weak target detection. Full article
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24 pages, 3798 KB  
Article
A Robust Tracking Method for Aerial Extended Targets with Space-Based Wideband Radar
by Linlin Fang, Yuxin Hu, Lihua Zhong and Lijia Huang
Remote Sens. 2025, 17(14), 2360; https://doi.org/10.3390/rs17142360 - 9 Jul 2025
Viewed by 376
Abstract
Space-based radar systems offer significant advantages for air surveillance, including wide-area coverage and extended early-warning capabilities. The integrated design of detection and imaging in space-based wideband radar further enhances its accuracy. However, in the wideband tracking mode, large aircraft targets exhibit extended characteristics. [...] Read more.
Space-based radar systems offer significant advantages for air surveillance, including wide-area coverage and extended early-warning capabilities. The integrated design of detection and imaging in space-based wideband radar further enhances its accuracy. However, in the wideband tracking mode, large aircraft targets exhibit extended characteristics. Measurements from the same target cross multiple range resolution cells. Additionally, the nonlinear observation model and uncertain measurement noise characteristics under space-based long-distance observation substantially increase the tracking complexity. To address these challenges, we propose a robust aerial target tracking method for space-based wideband radar applications. First, we extend the observation model of the gamma Gaussian inverse Wishart probability hypothesis density filter to three-dimensional space by incorporating a spherical–radial cubature rule for improved nonlinear filtering. Second, variational Bayesian processing is integrated to enable the joint estimation of the target state and measurement noise parameters, and a recursive process is derived for both Gaussian and Student’s t-distributed measurement noise, enhancing the method’s robustness against noise uncertainty. Comprehensive simulations evaluating varying target extension parameters and noise conditions demonstrate that the proposed method achieves superior tracking accuracy and robustness. Full article
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30 pages, 2752 KB  
Review
Application of Hyperspectral Imaging for Early Detection of Pathogen-Induced Stress in Cabbage as Case Study
by Magdalena Szechyńska-Hebda, Ryszard Hołownicki, Grzegorz Doruchowski, Konrad Sas, Joanna Puławska, Anna Jarecka-Boncela, Magdalena Ptaszek and Agnieszka Włodarek
Agronomy 2025, 15(7), 1516; https://doi.org/10.3390/agronomy15071516 - 22 Jun 2025
Cited by 1 | Viewed by 2561
Abstract
Cabbage (Brassica oleracea L.) is a globally significant vegetable crop that faces productivity challenges due to fungal and bacterial pathogens. This review highlights the potential of spectral imaging techniques, specifically multispectral and hyperspectral methods, in detecting biotic stress in cabbage, with a [...] Read more.
Cabbage (Brassica oleracea L.) is a globally significant vegetable crop that faces productivity challenges due to fungal and bacterial pathogens. This review highlights the potential of spectral imaging techniques, specifically multispectral and hyperspectral methods, in detecting biotic stress in cabbage, with a particular emphasis on pathogen-induced responses. These non-invasive approaches enable real-time assessment of plant physiological and biochemical changes, providing detailed spectral data to identify pathogens before visible symptoms appear. Hyperspectral imaging, with its high spectral resolution, allows for distinctions among different pathogens and the evaluation of stress responses, whereas multispectral imaging offers broad-scale monitoring suitable for field-level applications. The work synthesizes research in the existing literature while presenting novel experimental findings that validate and extend current knowledge. Significant spectral changes are reported in cabbage leaves infected by Alternaria brassicae and Botrytis cinerea. Early-stage detection was facilitated by alterations in flavonoids (400–450 nm), chlorophyll (430–450, 680–700 nm), carotenoids (470–520 nm), xanthophyll (520–600 nm), anthocyanin (550–560 nm, 700–710 nm, 780–790 nm), phenols/mycotoxins (700–750 nm, 718–722), water/pigments content (800–900 nm), and polyphenols/lignin (900–1000). The findings underscore the importance of targeting specific spectral ranges for early pathogen detection. By integrating these techniques with machine learning, this research demonstrates their applicability in advancing precision agriculture, improving disease management, and promoting sustainable production systems. Full article
(This article belongs to the Section Pest and Disease Management)
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24 pages, 5959 KB  
Article
An Information Geometry-Based Track-Before-Detect Algorithm for Range-Azimuth Measurements in Radar Systems
by Jinguo Liu, Hao Wu, Zheng Yang, Xiaoqiang Hua and Yongqiang Cheng
Entropy 2025, 27(6), 637; https://doi.org/10.3390/e27060637 - 14 Jun 2025
Cited by 1 | Viewed by 745
Abstract
The detection of weak moving targets in heterogeneous clutter backgrounds is a significant challenge in radar systems. In this paper, we propose a track-before-detect (TBD) method based on information geometry (IG) theory applied to range-azimuth measurements, which extends the IG detectors to multi-frame [...] Read more.
The detection of weak moving targets in heterogeneous clutter backgrounds is a significant challenge in radar systems. In this paper, we propose a track-before-detect (TBD) method based on information geometry (IG) theory applied to range-azimuth measurements, which extends the IG detectors to multi-frame detection through inter-frame information integration. The approach capitalizes on the distinctive benefits of the information geometry detection framework in scenarios with strong clutter, while enhancing the integration of information across multiple frames within the TBD approach. Specifically, target and clutter trajectories in multi-frame range-azimuth measurements are modeled on the Hermitian positive definite (HPD) and power spectrum (PS) manifolds. A scoring function based on information geometry, which uses Kullback–Leibler (KL) divergence as a geometric metric, is then devised to assess these motion trajectories. Moreover, this study devises a solution framework employing dynamic programming (DP) with constraints on state transitions, culminating in an integrated merit function. This algorithm identifies target trajectories by maximizing the integrated merit function. Experimental validation using real-recorded sea clutter datasets showcases the effectiveness of the proposed algorithm, yielding a minimum 3 dB enhancement in signal-to-clutter ratio (SCR) compared to traditional approaches. Full article
(This article belongs to the Section Information Theory, Probability and Statistics)
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19 pages, 4757 KB  
Article
Improved Adaptive Constant False Alarm Rate Detector Based on Fuzzy Theory for Multiple-Target Scenario
by Xudong Yang and Chunbo Xiu
Appl. Sci. 2025, 15(12), 6693; https://doi.org/10.3390/app15126693 - 14 Jun 2025
Viewed by 498
Abstract
An improved adaptive constant false alarm rate (CFAR) detector based on fuzzy theory is proposed to address the issue of poor detection performance and robustness of the variability index (VI) class CFAR detectors due to the misjudgment of the background environment and other [...] Read more.
An improved adaptive constant false alarm rate (CFAR) detector based on fuzzy theory is proposed to address the issue of poor detection performance and robustness of the variability index (VI) class CFAR detectors due to the misjudgment of the background environment and other reasons. The integration of the order statistic threshold adjustable detection algorithm (OSTA) into the adaptive CFAR detector has the potential to address the aforementioned issue. Therefore, in a clutter edge environment, the ratio of the means of the leading and lagging windows is calculated separately, and the differences between these mean ratios and predefined thresholds are used as inputs to the fuzzy inference machine, and the background clutter estimation of the OSTA is determined based on the fuzzy output, which can extend the range of values of the background clutter estimation, and improve the detection performance of the OSTA in this environment. The Kaigh–Lachenbruch quantile detection algorithm (KLQ) exhibits robust detection performance in multiple-target environments. Therefore, KLQ is used to detect targets in this environment, further improving the detection performance of the detector. The experimental results show that in multiple-target environments with an average misjudgment rate of 27.48%, the proposed detector increases the detection probability by 15.58% compared to the recently proposed variability index heterogeneous clutter estimate modified ordered statistics CFAR detector (VIHCEMOS-CFAR), and in a clutter edge environment, the false alarm rate of the proposed detector was reduced by approximately 89.64% compared to VIHCEMOS-CFAR. Additionally, the effectiveness of the proposed detector is also validated by real clutter data. It can be seen that the proposed adaptive CFAR detector has better robustness to the misjudgment of the background environment and better overall detection performance regardless of the environment. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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23 pages, 6234 KB  
Article
Characterizing Breast Tumor Heterogeneity Through IVIM-DWI Parameters and Signal Decay Analysis
by Si-Wa Chan, Chun-An Lin, Yen-Chieh Ouyang, Guan-Yuan Chen, Chein-I Chang, Chin-Yao Lin, Chih-Chiang Hung, Chih-Yean Lum, Kuo-Chung Wang and Ming-Cheng Liu
Diagnostics 2025, 15(12), 1499; https://doi.org/10.3390/diagnostics15121499 - 12 Jun 2025
Viewed by 2254
Abstract
Background/Objectives: This research presents a novel analytical method for breast tumor characterization and tissue classification by leveraging intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) combined with hyperspectral imaging techniques and deep learning. Traditionally, dynamic contrast-enhanced MRI (DCE-MRI) is employed for breast tumor diagnosis, but [...] Read more.
Background/Objectives: This research presents a novel analytical method for breast tumor characterization and tissue classification by leveraging intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) combined with hyperspectral imaging techniques and deep learning. Traditionally, dynamic contrast-enhanced MRI (DCE-MRI) is employed for breast tumor diagnosis, but it involves gadolinium-based contrast agents, which carry potential health risks. IVIM imaging extends conventional diffusion-weighted imaging (DWI) by explicitly separating the signal decay into components representing true molecular diffusion (D) and microcirculation of capillary blood (pseudo-diffusion or D*). This separation allows for a more comprehensive, non-invasive assessment of tissue characteristics without the need for contrast agents, thereby offering a safer alternative for breast cancer diagnosis. The primary purpose of this study was to evaluate different methods for breast tumor characterization using IVIM-DWI data treated as hyperspectral image stacks. Dice similarity coefficients and Jaccard indices were specifically used to evaluate the spatial segmentation accuracy of tumor boundaries, confirmed by experienced physicians on dynamic contrast-enhanced MRI (DCE-MRI), emphasizing detailed tumor characterization rather than binary diagnosis of cancer. Methods: The data source for this study consisted of breast MRI scans obtained from 22 patients diagnosed with mass-type breast cancer, resulting in 22 distinct mass tumor cases analyzed. MR images were acquired using a 3T MRI system (Discovery MR750 3.0 Tesla, GE Healthcare, Chicago, IL, USA) with axial IVIM sequences and a bipolar pulsed gradient spin echo sequence. Multiple b-values ranging from 0 to 2500 s/mm2 were utilized, specifically thirteen original b-values (0, 15, 30, 45, 60, 100, 200, 400, 600, 1000, 1500, 2000, and 2500 s/mm2), with the last four b-value images replicated once for a total of 17 bands used in the analysis. The methodology involved several steps: acquisition of multi-b-value IVIM-DWI images, image pre-processing, including correction for motion and intensity inhomogeneity, treating the multi-b-value data as hyperspectral image stacks, applying hyperspectral techniques like band expansion, and evaluating three tumor detection methods: kernel-based constrained energy minimization (KCEM), iterative KCEM (I-KCEM), and deep neural networks (DNNs). The comparisons were assessed by evaluating the similarity of the detection results from each method to ground truth tumor areas, which were manually drawn on DCE-MRI images and confirmed by experienced physicians. Similarity was quantitatively measured using the Dice similarity coefficient and the Jaccard index. Additionally, the performance of the detectors was evaluated using 3D-ROC analysis and its derived criteria (AUCOD, AUCTD, AUCBS, AUCTDBS, AUCODP, AUCSNPR). Results: The findings objectively demonstrated that the DNN method achieved superior performance in breast tumor detection compared to KCEM and I-KCEM. Specifically, the DNN yielded a Dice similarity coefficient of 86.56% and a Jaccard index of 76.30%, whereas KCEM achieved 78.49% (Dice) and 64.60% (Jaccard), and I-KCEM achieved 78.55% (Dice) and 61.37% (Jaccard). Evaluation using 3D-ROC analysis also indicated that the DNN was the best detector based on metrics like target detection rate and overall effectiveness. The DNN model further exhibited the capability to identify tumor heterogeneity, differentiating high- and low-cellularity regions. Quantitative parameters, including apparent diffusion coefficient (ADC), pure diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (PF), were calculated and analyzed, providing insights into the diffusion characteristics of different breast tissues. Analysis of signal intensity decay curves generated from these parameters further illustrated distinct diffusion patterns and confirmed that high cellularity tumor regions showed greater water molecule confinement compared to low cellularity regions. Conclusions: This study highlights the potential of combining IVIM-DWI, hyperspectral imaging techniques, and deep learning as a robust, safe, and effective non-invasive diagnostic tool for breast cancer, offering a valuable alternative to contrast-enhanced methods by providing detailed information about tissue microstructure and heterogeneity without the need for contrast agents. Full article
(This article belongs to the Special Issue Recent Advances in Breast Cancer Imaging)
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15 pages, 6302 KB  
Article
Fluorescent–Electrochemical–Colorimetric Triple-Model Immunoassays with Multifunctional Metal–Organic Frameworks for Signal Amplification
by Ning Xia, Chuye Zheng and Gang Liu
Biosensors 2025, 15(6), 376; https://doi.org/10.3390/bios15060376 - 11 Jun 2025
Cited by 1 | Viewed by 942
Abstract
Multimode immunoassays based on multiple response mechanisms have received great attention due to their capacity to effectively improve the accuracy and reliability of biosensing platforms. However, few strategies have been reported for triple-mode immunoassays due to the shortage of multifunctional sensing materials and [...] Read more.
Multimode immunoassays based on multiple response mechanisms have received great attention due to their capacity to effectively improve the accuracy and reliability of biosensing platforms. However, few strategies have been reported for triple-mode immunoassays due to the shortage of multifunctional sensing materials and the incompatibility of signal transduction methods in different detection modes. In this work, a fluorescent–electrochemical–colorimetric triple-mode immunoassay platform was proposed with Cu-based metal–organic frameworks (MOFs) as the signal labels. The captured Cu-MOFs were successfully decomposed under an acidic condition, leading to the release of numerous Cu2+ ions and 2-aminobenzene-1,4-dicarboxylic acid (NH2-BDC) ligands. The released NH2-BDC were determined by fluorescence titration. Meanwhile, the released Cu2+ were readily quantified by differential pulse voltammetry (DPV) and simply detected through the catalytic oxidation of chromogenic substrate 3,3′,5,5′-tetramethylbenzidine (TMB). Taking alpha-fetoprotein (AFP) as a model analyte, the designed triple-mode immunoassays showed good performances with the linear range of 10–200 pg/mL, 10–200 pg/mL, and 1–100 pg/mL for the fluorescent, electrochemical, and colorimetric modes, respectively. The proposed triple-mode biosensing platforms show great potential for the applications in disease diagnosis, since they can be easily extended to other bioassays by changing the targets and recognition elements. Full article
(This article belongs to the Special Issue Signal Amplification in Biosensing)
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33 pages, 12604 KB  
Article
YOLO-SCNet: A Framework for Enhanced Detection of Small Lunar Craters
by Wei Zuo, Xingye Gao, Di Wu, Jiaqian Liu, Xingguo Zeng and Chunlai Li
Remote Sens. 2025, 17(11), 1959; https://doi.org/10.3390/rs17111959 - 5 Jun 2025
Viewed by 1440
Abstract
The study of impact craters is crucial for understanding planetary evolution and geological processes, particularly small craters, which are key to reconstructing the lunar impact history. Detecting small craters, with diameters ranging from 0.2 to 2 km, remains a challenge due to the [...] Read more.
The study of impact craters is crucial for understanding planetary evolution and geological processes, particularly small craters, which are key to reconstructing the lunar impact history. Detecting small craters, with diameters ranging from 0.2 to 2 km, remains a challenge due to the power-law distribution of crater sizes and the complex topography of the lunar surface. This work uses high-resolution lunar imagery data from the Chang’E-2 mission, with a 7 m spatial resolution, to develop a deep learning framework for small crater detection, named YOLO-SCNet. The framework combines a high-quality, diversified sample dataset, generated through data augmentation techniques, with YOLO-SCNet, specifically designed for small target detection. Key challenges in lunar crater detection, such as varying lighting conditions and complex terrains, are addressed through the innovative model architecture, which incorporates a small object detection head, dynamic anchor boxes, and multi-scale feature fusion. Experimental results demonstrate that YOLO-SCNet achieves outstanding performance in detecting small craters across different lunar regions, with precision, recall, and F1 scores of 90.2%, 88.7%, and 89.4%, respectively. The framework offers a scalable solution for constructing a global lunar crater catalog (≥0.2 km) and can be extended to other planetary bodies like Mars and Mercury, significantly supporting future planetary exploration and mapping efforts. Full article
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23 pages, 1166 KB  
Review
Molecular Insights into Rice Immunity: Unveiling Mechanisms and Innovative Approaches to Combat Major Pathogens
by Muhammad Usama Younas, Bisma Rao, Muhammad Qasim, Irshad Ahmad, Guangda Wang, Quanyi Sun, Xiongyi Xuan, Rashid Iqbal, Zhiming Feng, Shimin Zuo and Maximilian Lackner
Plants 2025, 14(11), 1694; https://doi.org/10.3390/plants14111694 - 1 Jun 2025
Cited by 2 | Viewed by 1194
Abstract
Rice (Oryza sativa) is a globally important crop that plays a central role in maintaining food security. This scientific review examines the critical role of genetic disease resistance in protecting rice yields, dissecting at the molecular level how rice plants detect [...] Read more.
Rice (Oryza sativa) is a globally important crop that plays a central role in maintaining food security. This scientific review examines the critical role of genetic disease resistance in protecting rice yields, dissecting at the molecular level how rice plants detect and respond to pathogen attacks while evaluating modern approaches to developing improved resistant varieties. The analysis covers single-gene-mediated and multi-gene resistance systems, detailing how on one hand specific resistance proteins, defense signaling components, and clustered loci work together to provide comprehensive protection against a wide range of pathogens and yet their production is severely impacted by pathogens such as Xanthomonas oryzae (bacterial blight) and Magnaporthe oryzae (rice blast). The discussion extends to breakthrough breeding technologies currently revolutionizing rice improvement programs, including DNA marker-assisted selection for accelerating traditional breeding, gene conversion methods for introducing new resistance traits, and precision genome editing tools such as CRISPR/Cas9 for enabling targeted genetic modifications. By integrating advances in molecular biology and genomics, these approaches offer sustainable solutions to safeguard rice yields against evolving pathogens. Full article
(This article belongs to the Special Issue Rice-Pathogen Interaction and Rice Immunity)
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