Search Results (3,418)

Respiratory syncytial virus (RSV) is a major cause of severe respiratory infections, particularly in infants and young children. Although disinfection methods using alcohol and detergents are effective, their application in pediatric environments poses safety concerns. Ozone (O₃) has been employed for water treatment, food preservation, and air purification, but its efficacy against RSV has not been well studied. Here, we investigated the inactivation of RSV using a dielectric barrier discharge (DBD)-based ozone generator (SFG1210). The RSV A2 strain was spotted on glass coverslips and exposed to low-concentration ozone (0.5 ppm) for 1 h under controlled temperature (24.6~27.2 °C) and relative humidity (71.9~75.1%) conditions. Subsequent infectivity assays combined with immunochromatography showed that ozone exposure significantly reduced RSV infectivity. Specifically, viral titration assay of median tissue culture infectious dose (TCID₅₀) showed that RSV titers were reduced by more than 6 logs. In addition, biochemical analyses showed significant reductions in intact RSV genomic RNA and F protein levels after ozone treatment, suggesting that ozone inactivates RSV by damaging both the viral genome and surface proteins. These findings demonstrate the potential applicability of the SFG1210 ozone generator as an effective tool for surface disinfection of RSV, providing a safe, non-contact, and practical approach for infection control in healthcare and childcare settings. Full article

Water removal is crucial in natural gas processing to minimize water content, ensure safe transmission, and prevent operational issues like equipment corrosion and hydrate formation. Glycol absorption could be considered as one of the most effective methods used for natural gas dehydration and dew point control. However, during solvent regeneration, some pollutants, like benzene, toluene, ethylbenzene, and xylene (BTEX), are released to the atmosphere, resulting in catastrophic physical and mental health problems. Minimizing such pollutants that have negative impacts is highly needed to avoid the related negative environmental consequences. The objective of the current work is to investigate alternative strategies targeted to minimize BTEX emissions and guarantee efficient control of the dew point. Two strategies are introduced and investigated in this work; the first strategy is based on revamping an existing unit by adding a new cooler upstream glycol inlet separator, while the second strategy is based on using alternative glycols. The proposed strategies are applied to an Egyptian natural gas dehydration unit to select the optimum scenario that achieves the minimum BTEX emissions with efficient dew point control. It is found that natural gas dehydration using monoethylene glycol (MEG) is the best scenario in reducing BTEX emissions with efficient dew point control. The impact of operating conditions on BTEX emissions, along with natural gas water content, is also investigated. Lingo optimization software, v. 18, as well as HYSYS, v. 14, are used to find the optimum operating conditions for efficient dew point control with minimum BTEX emissions. It is demonstrated that stripping gas, MEG circulation rate, and inlet feed gas temperature have remarkable effects on BTEX emissions. Two quadratic correlations are also introduced in this study to efficiently relate BTEX emissions and water dew point to the influencing operating conditions. Full article

Access to safe water and sanitation remains a pressing challenge in Sub-Saharan Africa. Rapid urbanisation, fragile governance, and increasing climate hazards continue to undermine the sustainability of WASH (Water, Sanitation and Hygiene) services. This study examines whether Mozambique’s normative and institutional framework effectively supports sustainable urban WASH service delivery in Beira, the country’s second-largest city. Combining a critical policy review with six semi-structured interviews involving institutional actors and community leaders, the research employs a qualitative, phenomenological design to explore the interaction between national frameworks and local practices. Findings reveal five interrelated dimensions shaping sustainability: governance coordination, infrastructure robustness and maintenance, community participation, climate resilience, and financial viability. Although post-disaster investments and recent policy reforms have led to improvements, significant challenges persist. These include overlapping institutional mandates, underdeveloped preventive maintenance systems, limited recognition and support for community-led initiatives, fragmented climate adaptation efforts, and strong dependence on external funding. The study also reveals how historical legacies, particularly colonial-era governance structures, continue to shape water and sanitation delivery. By integrating policy analysis with local perspectives, the paper contributes to debates on WASH sustainability in African cities, particularly in climate-vulnerable secondary urban centres. It highlights the need for systemic reforms that clarify institutional roles, institutionalise maintenance practices, formalise community engagement, embed nature-based adaptation strategies, and strengthen financial transparency. These changes are essential if Beira, and similar cities across sub-Saharan Africa, are to achieve Sustainable Development Goal 6 under mounting climate pressure. Full article

This study presents a systematic analysis of the stability and roll characteristics of an Oscillating Water Column (OWC) wave energy buoy. By integrating theoretical derivation and AQWA simulation, the research identifies thirteen possible heeling states of OWC buoy, focusing on five representative states applicable to the current design. A novel segmented-integration model is proposed to compute the centre of buoyancy and righting moment for the hollow-annular OWC buoy, accurately capturing the evolution of static and dynamic stability across heel angles from 0° to 90°. Results show that the buoy has an initial metacentric height of 0.33 m, a maximum righting arm of 0.713 m, a limiting static heel angle of 77°, and a minimum capsizing moment of 22,887 N·m—all significantly exceeding regulatory requirements. The roll natural period ranges from 5.8 to 7.7 s, with a tuning factor above 1.3, effectively avoiding resonance with typical wave periods in the target sea area. The buoy demonstrates excellent dynamic stability and capsize resistance. This study fills a gap in OWC buoy stability analysis and provides a practical guidance for the safe design of wave energy devices. Full article

The swallowing reflex is a highly coordinated process that is essential for safe bolus transit and airway protection. Although its neurophysiological framework has been extensively studied, the molecular mechanisms underlying reflex initiation remain incompletely understood, limiting targeted therapies for oropharyngeal dysphagia. Recent evidence implicates purinergic signaling as a key mediator of swallowing initiation, particularly through ATP release from taste buds and neuroendocrine cells in the hypopharyngeal and laryngeal mucosa. Experimental studies in mice demonstrate that water, acidic, and bitter chemical stimuli induce ATP release, activating purinergic receptors (P2X2, P2X3, heteromeric P2X2/P2X3, and P2Y1) on afferent sensory fibers. This receptor activation enhances input to the brainstem swallowing central pattern generator, initiating reflexive swallowing. Genetic ablation of purinergic receptor-expressing neurons or epithelial sentinel cells, as well as pharmacological antagonism of P2X or P2X3 receptors, markedly attenuates these responses. Furthermore, exogenous ATP or selective P2X3 agonists applied to swallowing-related mucosa evoke swallowing reflexes in an animal model, underscoring translational potential. While the precise upstream receptor mechanisms for water- and acid-induced ATP release, as well as species-specific differences, remain to be clarified, targeting purinergic pathways may represent a novel physiologically grounded therapeutic strategy for restoring swallowing function in patients with oropharyngeal dysphagia. Full article

The provision of potable water for armed forces at their operational sites necessitates a robust treatment chain to ensure the production of safe drinking water from potentially contaminated local water sources. Relying on single-use water bottles is not considered an eco-friendly option and on-site production may exhibit limited efficiency depending on the water contamination. This study therefore aimed to define a mobile processing chain that could efficiently produce drinking water on-site while offering a multi-barrier level of protection. To evaluate the system, contaminated water was prepared from different water sources and then spiked with various inorganic contaminants (metals, anions: Cl⁻, F⁻, I⁻, NO₂⁻, NO₃⁻, SO₄²⁻, CN⁻), organic contaminants (e.g., pesticides, petroleum hydrocarbons, polycyclic aromatic hydrocarbons, chlorinated solvents), and energetic compound (perchlorate) at levels ranging from 5 to 50 times the standard water quality criteria. A specific treatment process was defined optimized and evaluated at flow rates reaching 500 L/h. This treatment chain includes the following: a sediment filter, a greensand filter, a cation exchange resin, an anion exchange resin, an activated carbon adsorption filter, ultrafiltration, a UV lamp, and a reverse osmosis (RO) unit. This treatment system successfully met all water quality criteria, providing a reliable and effective alternative to an RO-only treatment regime. Full article

The aim of this study was to compare the effectiveness of edible oil (as an extractant) for the extraction of CA (carnosic acid), C (carnosol), and RA (rosmarinic acid) from sage with popular solvents (methanol, ethanol, 70% methanol, 70% ethanol, and water), as well as to assess the stability and fit the kinetic reaction model to the course of CA and RA degradation in oil macerate and various extracts. The degradation rate constant and half-life of CA and RA were also estimated and compared. CA was most efficiently extracted from sage using ethanol and methanol (9.3–10.1 mg/g of sage), followed by oil (7.10 mg/g). For C and RA, the most suitable solvents were 70% ethanol and 70% methanol (C: 3.08–4.01 mg/g; RA: 19.16–20.24 mg/g). CA was most stable in oil, followed by ethanol > methanol > 70% ethanol > 70% methanol. CA degradation followed a first-order kinetic model. RA was very stable in all extracts, except water, where the kinetics of RA degradation most closely followed a second-order model. Although oil extracts smaller amounts of phytochemicals from sage than solvents, CA in oil was the most stable, and the maceration of sage in oil is safe and consistent with the concept of sustainable development. Full article

Protected areas are essential for conserving biodiversity and sustaining ecosystems, yet their effective management requires a clear understanding of soil and water quality, which underpin ecological processes. This study evaluated 15 soil and seven water samples to assess their physico-chemical properties, focusing on heavy metal concentrations. Results showed that soils were generally neutral to alkaline, with Hashwan-2 exhibiting the highest concentrations of calcium (26.5 meq/L), magnesium (11.2 meq/L), carbonates (0.32 meq/L), bicarbonates (3.66 meq/L), and chloride (35.43 meq/L). Heavy metal analysis indicated elevated nickel (51.628 mg/kg) and chromium (76.29 mg/kg) at Albuyitlar-2, and chromium (68.015 mg/kg) at Shabak-Mateam-1 1 1, exceeding US-EPA permissible limits of 45 mg/kg for nickel and 64 mg/kg for chromium. Water samples revealed high levels of aluminum (12.681 mg/L), manganese (0.146 mg/L), and iron (7.055 mg/L), also exceeding the US-EPA thresholds of 0.2, 0.1, and 0.5 mg/L, respectively. In contrast, more toxic metals such as arsenic, cadmium, lead, and mercury remained within safe limits. These findings highlight localized concerns regarding heavy metal contamination that warrant continued monitoring to ensure ecosystem health. Full article

Hydrogen-rich gas (HRG) injection is a promising low-carbon solution for blast furnace ironmaking. This study conducted numerical simulations in the lower part of a blast furnace to analyze the combustion behavior of coinjected coke oven gas (COG) and pulverized coal (PC) within the raceway and the associated thermal load on the tuyere. A three-dimensional computational fluid dynamics model incorporating fluid–thermal–solid coupling and the GRI-Mech 3.0 chemical kinetic mechanism (validated for 300–2500 K) was established to simulate the lance–blowpipe–tuyere–raceway region. The simulation results revealed that moderate COG injection accelerated volatile release from PC and enlarged the high-temperature zone (>2000 K). However, excessive COG injection intensified oxygen competition and shortened the residence time of PC, ultimately decreasing the burnout rate. Notably, although COG has high reactivity, its injection did not cause an increase in tuyere temperature. By contrast, the presence of an unburned gas layer near the upper wall of the tuyere and the existence of a strong convective cooling effect contributed to a reduction in tuyere temperature. An optimized cooling water channel was designed to enhance flow distribution and effectively suppress localized overheating. The findings of this study offer valuable technical insights for ensuring safe COG injection and advancing low-carbon steelmaking practices. Full article

The accurate real-time delineation of overburden failure zones, specifically the caved and water-conducted fracture zones, remains a significant challenge in longwall mining, as conventional monitoring methods often lack the spatial continuity and resolution for precise, full-profile strain measurement. Based on the hydrogeological data of the E9103 working face in Hengjin Coal Mine, a numerical calculation model for the overburden strata of the E9103 working face was established to simulate and analyze the stress distribution, failure characteristics, and development height of the water-conducting fracture zones in the overburden strata of the working face. To address this problem, this study presents the application of a distributed optical fiber sensing (DOFS) system, centering on an innovative fiber installation technology. The methodology involves embedding the sensing fiber into boreholes within the overlying strata and employing grouting to achieve effective coupling with the rock mass, a critical step that restores the in situ geological environment and ensures measurement reliability. Field validation at the E9103 longwall face successfully captured the dynamic evolution of the strain field during mining. The results quantitatively identified the caved zone at a height of 13.1–16.33 m and the water-conducted fracture zone at 58–60.6 m. By detecting abrupt strain changes, the system enables the back-analysis of fracture propagation paths and the identification of potential seepage channels. This work demonstrates that the proposed DOFS-based monitoring system, with its precise spatial resolution and real-time capability, provides a robust scientific basis for the early warning of roof hazards, such as water inrushes, thereby contributing to the advancement of intelligent and safe mining practices. Full article

The disposal of coal mine solid waste has always been a challenge in the coal mining production process, and the research and development of low-cost and high-performance filling materials is a prerequisite for achieving large-scale disposal of coal mine solid waste. The effects of water–cement ratio, foaming agent dilution ratio, foam agent content, foam stabilizer content, and gypsum content on the mechanical properties, transportation characteristics, and microstructure of cement foam filling materials were studied by laboratory test methods. The optimal ratio of cement foam filling material for comprehensive performance was determined. On this basis, the mechanism of influence of fly ash content, gangue content, and gangue particle size on the mechanics, transportation characteristics, and microstructure of foam filling materials was further studied. The experimental results show that at fly ash contents below 30%, gangue content is less than 30%. The particle size of gangue is less than 0.6 mm, and the expansion ratio of coal mine solid waste foam filling material is about three times, which has good mechanical properties and transportation performance. The on-site test results show that the control effect of the surrounding rock in the goaf is good, achieving safe and efficient mining of the working face. Full article

Rice is a safe and widely consumed gluten-free grain; however, breads prepared from white rice flour, such as Taichung Sen 17 (TS17), are prone to rapid staling and typically lack sufficient dietary fiber and bioactive compounds. To address these limitations, this study investigated the effects of partially replacing TS17 flour with indica black rice (B) flour, varying water content, and incorporating the natural hydrocolloid konjac glucomannan (K) on the quality of rice batter and bread. Compared with TS17 flour, B flour contained higher levels of total dietary fiber, total phenols, total anthocyanins, and antioxidant capacity. Substituting 15% of TS17 with B flour slightly increased the bread volume from 1032 mL to 1042 mL under 92% water addition (1.01-fold). More notably, it significantly increased the volume from 872 mL to 917 mL under 107% water (1.05-fold), and from 642 mL to 775 mL under 122% water (1.21-fold). However, higher substitution levels of B flour resulted in a reduction in loaf volume. Further incorporation of 2% K under 122% water conditions (TS17B15K2.0-122) resulted in the highest loaf volume of 1063 mL, representing a significant 1.37-fold increase compared to TS17B15-122 (775 mL), and exhibited the slowest staling rate after 24 h. Although K significantly improved bread texture and moisture retention, excessive addition may accelerate staling due to insufficient water availability in the formulation. These findings highlight that combining TS17 flour, B flour, and konjac gum represents a feasible and sustainable strategy for developing functional gluten-free baked products targeted at health-conscious and gluten-intolerant consumers. Full article

Cyclic nitramine explosives such as octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) are xenobiotics that are utilized in a variety of propellants and traditional weapons. The primary source of water contamination is the industrial use of these hazardous substances in propellants and wastewater generated from munitions production facilities. These chemicals have a negative impact on human health and ecosystems. It is necessary to remove these toxic compounds from the environment safely because their production and usage have seriously contaminated soil and groundwater. Although there are no widely adopted WHO or US federal Maximum Contaminant Levels (MCLs) for military explosives, the health advisory limits for RDX in drinking water are 2 µg/L, and for HMX are 400 µg/L. Numerous traditional treatment approaches that incorporate physical, biological, and chemical processes have been used to decontaminate explosive wastewater. However, contaminants are not completely mineralized by these methods. Complete reduction of these chemicals can be accomplished by combining suitable methods. For the remediation of explosive effluent, integrated treatment systems that combine the effectiveness of biological and physical-chemical methods have shown promising results. This review discusses the toxicity and some physical–chemical–biological and combined treatment processes of wastewater polluted by these explosive contaminants. Full article

Focusing on the mining-induced fracture development characteristics of Weakly Cemented Overburden (WCO) in Ultra-Thick Coal Seam (UTCS) extraction, this study, based on the 1101 first mining face in Xinjiang’s Zhundong Coalfield, systematically investigates the dynamic evolution law of the water-conducting fracture zone (WCFZ) in WCO by employing similarity simulation, quantitative characterization using Fractal Dimension (D), and surface borehole exploration and borehole imaging technology. The results show that existing prediction equations for the WCFZ have poor applicability in the study area, with significant fluctuations in prediction outcomes. Similarity simulation reveals that Thick Soft Rock Layers (TS) guide and control fracture development, with the D exhibiting a “step-like” evolution. After the first rupture of TS1, the peak D reaches 1.49, stabilizing between 1.36 and 1.37 after full extraction. The height of the WCFZ increases non-linearly with the advance of the working face, reaching a maximum of 189 m, with a fracture-to-mining ratio of 10.5. Based on D fluctuations and extension patterns, the fracture development is divided into three stages, initial development, vertical propagation, and stabilization, clarifying its spatial evolution. Field measurements indicate a WCFZ height ranging from 161 to 178 m, with a fracture-to-mining ratio of 9.73–12.18, showing only a 6.2% error compared to the simulation results, which verifies the reliability of the experiment. This study reveals the evolution mechanism of the WCFZ during mining in UTCS and WCO in the Zhundong area, providing a theoretical basis and practical guidance for mine disaster prevention and control, as well as safe and efficient mining. Full article

This study examines the multidimensional human security challenges faced by internally displaced persons (IDPs) in Adigrat City, Tigray, Ethiopia, in the context of conflict-induced displacement. Guided by the Human Security Framework, the analysis addresses threats across economic, food, health, environmental, personal, community, and political domains. Data were collected through a cross-sectional survey using structured questionnaires administered to a stratified sample of 349 IDPs, and analysed through descriptive statistics. Content analysis was conducted on interviews from 17 respondents who were selected purposefully, and secondary data was collected to understand IDPs’ experiences and institutional responses. The findings reveal severe and overlapping forms of deprivation: IDPs reside in overcrowded and inadequate shelters, face chronic food insecurity, and lack access to clean water, healthcare, and education. These conditions are compounded by psychosocial distress, including trauma, anxiety, and the erosion of social cohesion. The study finds that governmental and international responses remain limited, poorly coordinated, and insufficiently responsive to the complex needs of displaced people. While the voluntary, safe, and dignified return of displaced populations to their areas of origin should remain the ultimate objective, this outcome could be realized by fully implementing the Pretoria Cessation of Hostilities Agreement. Responses including improved shelter, essential services access, livelihood recovery, and mental health support systems are essential to address urgent needs. Full article