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18 Results Found

  • Article
  • Open Access
1,441 Views
14 Pages

30 August 2025

Corneal sequestrum, also known as corneal mummification or necrosis, is a common complication of corneal ulceration in cats, with brachycephalic and pure-bred cats being the most affected. This prospective clinical trial aimed to evaluate the efficac...

  • Article
  • Open Access
8 Citations
4,052 Views
13 Pages

Lamellar Keratoplasty Using Acellular Bioengineering Cornea (BioCorneaVetTM) for the Treatment of Feline Corneal Sequestrum: A Retrospective Study of 62 Eyes (2018–2021)

  • Huihao Xu,
  • John S. Sapienza,
  • Yipeng Jin,
  • Jiahao Lin,
  • Xiaobo Zheng,
  • Haodi Dong,
  • Hongxiu Diao,
  • Ying Zhao,
  • Jiafeng Gao and
  • Degui Lin
  • + 4 authors

13 April 2022

To retrospectively evaluate the effectiveness and outcome of lamellar keratoplasty using acellular bioengineering cornea (BioCorneaVetTM) for the treatment of feline corneal sequestrum (FCS). The medical records of cats diagnosed with FCS that underw...

  • Case Report
  • Open Access
1 Citations
3,437 Views
9 Pages

17 August 2022

Background: Medication-Related Osteonecrosis of the Jaw (MRONJ) can occur as an adverse reaction to several antiresorptive medications such as bisphosphonate. It presents clinically as a necrotic exposed bone. Several factors including tooth extracti...

  • Case Report
  • Open Access
4 Citations
3,157 Views
11 Pages

Pulmonary Sequestration: A Monocentric Case Series Report

  • Michail Galanis,
  • Estelle Sommer,
  • Konstantinos Gioutsos,
  • Thanh-Long Nguyen and
  • Patrick Dorn

28 September 2024

Purpose: Pulmonary sequestration is a rare pulmonary malformation that often necessitates surgical intervention due to potential complications such as recurrent infections or hemoptysis. This case series presents the clinical trajectory of four patie...

  • Article
  • Open Access
6 Citations
3,047 Views
9 Pages

Genetic Aspects of Corneal Sequestra in a Population of Persian, Himalayan and Exotic Cats

  • Tom Schipper,
  • Goedele Storms,
  • Gerlinde Janssens,
  • Sabine Schoofs,
  • Eveline Capiau,
  • Dieter Verdonck,
  • Pascale Smets,
  • Luc J. Peelman and
  • Bart J. G. Broeckx

8 August 2022

Corneal sequestra are ophthalmic lesions that are remarkably common in Persian, Himalayan and exotic cats. In this study, the genetic aspects of this disease were investigated in a population of cats originating from a single cattery. Odds ratios wer...

  • Case Report
  • Open Access
13 Citations
1,073 Views
4 Pages

Chronic Suppurative Osteomyelitis of Mandible: A Case Report

  • Hemant Mehra,
  • Sumit Gupta,
  • Hemant Gupta,
  • V. Sinha and
  • Jasmeet Singh

Osteomyelitis is an inflammatory disease of the bone that usually begins as an infection of the medullary cavity, rapidly involves the haversian system, and quickly extends to the periosteum of the area. It develops in the jaws after a chronic odonto...

  • Article
  • Open Access
9 Citations
3,622 Views
10 Pages

Relationship between Drug Holidays of Antiresorptive Agents and Surgical Outcomes in Cancer Patients with Medication-Related Osteonecrosis of the Jaw

  • Mitsunobu Otsuru,
  • Sakiko Soutome,
  • Keisuke Omori,
  • Koki Suyama,
  • Kota Morishita,
  • Saki Hayashida,
  • Maho Murata,
  • Yukinori Takagi,
  • Miho Sasaki and
  • Masahiro Umeda
  • + 4 authors

It is controversial as to whether the withdrawal of antiresorptive (AR) agents is necessary while treating medication-related osteonecrosis of the jaw (MRONJ). In this study, we investigated whether a drug holiday promoted sequestrum separation and i...

  • Article
  • Open Access
195 Views
18 Pages

15 January 2026

Objectives: This study aimed to evaluate the radiographic characteristics of medication-related osteonecrosis of the jaw (MRONJ) by digital panoramic radiographs and to investigate the associations between radiographic findings and clinical, demograp...

  • Case Report
  • Open Access
2 Citations
2,861 Views
16 Pages

Use of a Custom-Made Patellar Groove Replacement in an American Staffordshire Terrier Puppy with a Severe Bone Defect in the Femoral Trochlea Caused by Hematogenous Osteomyelitis

  • Enrico Panichi,
  • Sara Sassaroli,
  • Giorgio Maria Ciccarese,
  • Valentina Riccio,
  • Caterina Balestriere,
  • Marco Barbaccia,
  • Fulvio Cappellari,
  • Ekaterina Burkhan and
  • Angela Palumbo Piccionello

15 March 2024

An 8-month-old male American Staffordshire terrier was referred for a no-weightbearing lameness of the right pelvic limb, hyperthermia, lethargy and inappetence. Two months before, endocarditis was diagnosed and treated in another veterinary hospital...

  • Article
  • Open Access
3,316 Views
15 Pages

Recurrent vs. Nonrecurrent Superficial Non-Healing Corneal Ulcers in Cats: A Multifactorial Retrospective Analysis

  • Nuanwan Rujirekasuwan,
  • Panpicha Sattasathuchana,
  • Natthanet Sritrakoon and
  • Naris Thengchaisri

16 July 2025

Feline superficial non-healing corneal ulcers are persistent lesions requiring individualized treatment to reduce recurrence. This retrospective study evaluated 136 affected eyes (113 nonrecurrent; 23 recurrent) to identify clinical and treatment-rel...

  • Article
  • Open Access
6 Citations
3,600 Views
9 Pages

Detectability of Osseous Lesions with a Pre-Programmed Low-Dose Protocol for Cone-Beam Computed Tomography

  • Quirin Döbelin,
  • Bernd Stadlinger,
  • Daniel B. Wiedemeier,
  • Dominique Bichsel,
  • Martin Rücker and
  • Silvio Valdec

19 July 2020

The present study aimed to compare the diagnostic reliability of a pre-set, manufacturer-specific, low-dose mode against a standard-dose mode in the detection of four different osseous lesions in the mandible with cone-beam computed tomography (CBCT)...

  • Systematic Review
  • Open Access
4 Citations
3,480 Views
16 Pages

Impact of COVID-19 Disease on the Development of Osteomyelitis of Jaws: A Systematic Review

  • Emmanouil Vardas,
  • Daniela Adamo,
  • Federica Canfora,
  • Maria Kouri,
  • Konstantina Delli,
  • Michele Davide Mignogna and
  • Nikolaos Nikitakis

23 July 2024

Background/Objectives: Osteomyelitis is characterized by an inflammatory process affecting both bone and bone marrow, leading to cell death and the formation of bone sequestrum. Recent literature from the past five years has documented instances of o...

  • Review
  • Open Access
4 Citations
3,524 Views
15 Pages

Could MRONJ Be Related to Osimertinib Monotherapy in Lung Cancer Patients after Denosumab Suspension?

  • Marta Forte,
  • Antonio d’Amati,
  • Luisa Limongelli,
  • Massimo Corsalini,
  • Gianfranco Favia,
  • Giuseppe Ingravallo,
  • Giuseppe Barile and
  • Saverio Capodiferro

10 February 2024

Background: Medication-related osteonecrosis of the jaws is the most frequent complication in patients treated or in therapy with antiresorptive/antiangiogenetic drugs. The list of medications possibly related to MRONJ onset is constantly growing; we...

  • Article
  • Open Access
21 Citations
3,739 Views
11 Pages

Ozone Infiltration for Osteonecrosis of the Jaw Therapy: A Case Series

  • Olga Di Fede,
  • Carmine Del Gaizo,
  • Vera Panzarella,
  • Gaetano La Mantia,
  • Pietro Tozzo,
  • Anna Di Grigoli,
  • Antonio Lo Casto,
  • Rodolfo Mauceri and
  • Giuseppina Campisi

9 September 2022

Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction, mainly due to bone-modifying agents (BMA), and it is a potentially painful and debilitating condition. To date, the literature has reported a 90% rate of successful ou...

  • Article
  • Open Access
43 Citations
5,703 Views
16 Pages

Conservative Management of Medication-Related Osteonecrosis of the Jaws (MRONJ): A Retrospective Cohort Study

  • Elena M. Varoni,
  • Niccolò Lombardi,
  • Giulio Villa,
  • Alberto Pispero,
  • Andrea Sardella and
  • Giovanni Lodi

17 February 2021

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a severe side effect of bisphosphonates and anti-resorptive drugs prescribed for treatment of severe osteoporosis, Paget’s disease, and bone malignancies. The aim of this study was to...

  • Article
  • Open Access
297 Views
12 Pages

Decoding Osteoradionecrosis of the Jaw: Radiological Progression and a Novel CT-Based Grading System

  • Vasundhara Patil,
  • Pritesh Shah,
  • Abhishek Mahajan,
  • Nilesh Sable,
  • Anuradha Shukla,
  • Gauri Bornak,
  • Swapnil Rane,
  • Sandeep Gurav,
  • Sarbani Ghosh Laskar and
  • Pankaj Chaturvedi
  • + 18 authors

6 January 2026

Background: Osteoradionecrosis (ORN) of the jaw is a severe, progressive complication of radiation therapy for head and neck malignancies. ORN features radiologically overlaps osteomyelitis and tumor recurrence. This study analyzes jaw ORN imaging ch...

  • Article
  • Open Access
495 Views
23 Pages

19 December 2025

Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse event triggered by antiresorptive and/or anti-angiogenic agents, characterized by bone destruction, sequestrum formation, and refractory mucosal defects. Effective mucosal healin...

  • Article
  • Open Access
2 Citations
2,469 Views
18 Pages

Ozone Therapy and Negative Pressure Wound Therapy in the Treatment of Difficult-to-Heal Wounds in Diabetic Foot Syndrome and Charcot Neuroarthropathy

  • Agnieszka Białomyzy,
  • Katarzyna Kotrych,
  • Anna Bogacz,
  • Marta Podralska,
  • Aleksandra Górska,
  • Jacek Białecki,
  • Izabela Uzar,
  • Bogusław Czerny and
  • Adam Kamiński

6 June 2025

Diabetes, as one of the most common diseases of civilization, is a significant factor of mortality worldwide. Undiagnosed and improperly treated, it leads to the development of a number of complications, including diabetic foot syndrome (DFS) and Cha...