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13 pages, 656 KB  
Article
Wintering Red Kites in Central Spain: Macrohabitat Selection and Population Density Estimate
by Alan Omar Bermúdez-Cavero, Edgar Bernat-Ponce, José Antonio Gil-Delgado and Andrés López-Peinado
Birds 2025, 6(4), 54; https://doi.org/10.3390/birds6040054 (registering DOI) - 13 Oct 2025
Abstract
The Red Kite (Milvus milvus), a Western Palearctic raptor, experienced a severe population decline across its range during the 19th and 20th centuries, nearly disappearing as a breeding species in Spain. Although conservation and reintroduction efforts have facilitated recovery, information on [...] Read more.
The Red Kite (Milvus milvus), a Western Palearctic raptor, experienced a severe population decline across its range during the 19th and 20th centuries, nearly disappearing as a breeding species in Spain. Although conservation and reintroduction efforts have facilitated recovery, information on its wintering ecology remains limited. We evaluated the population size and habitat selection of wintering Red Kites in and around the La Mancha Húmeda Biosphere Reserve (MHBR), Central Spain, and assessed whether survey route type affected detectability. Surveys comprised 325 vehicle-based line transects along paved roads and dirt tracks during the winters of 2021–2022 and 2022–2023, and the 2022 breeding season. Detection rates and density did not differ between route types. Across 212 winter transects, we recorded 124 individuals, with none detected during 113 breeding season transects. Density estimates were consistent across winters (1.3–1.4 individuals/km2), yielding a population estimate of approximately 1430 individuals. Habitat analysis indicated clear selection for open agricultural mosaics dominated by fallow land and vineyards, while rugged terrain was avoided. These results identify MHBR as an important wintering area. Yet, super-intensive agriculture is a poor habitat due to its uniformity. Enhancing heterogeneous open landscapes, including farmland, is essential for Red Kite colonization and expansion. Full article
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23 pages, 1618 KB  
Article
Integrated Algorithmic Strategies for Online Food Delivery Routing: A Multi-Stakeholder Optimization Approach
by Seçkin Ünver, Gülfem Tuzkaya and Serol Bulkan
Processes 2025, 13(10), 3211; https://doi.org/10.3390/pr13103211 - 9 Oct 2025
Viewed by 193
Abstract
The dynamic and time-sensitive nature of online food delivery, along with real-world factors like sudden changes in order volumes and the availability of couriers, distinguishes it from traditional vehicle routing scenarios. Apart from the many studies in the literature that handle this problem [...] Read more.
The dynamic and time-sensitive nature of online food delivery, along with real-world factors like sudden changes in order volumes and the availability of couriers, distinguishes it from traditional vehicle routing scenarios. Apart from the many studies in the literature that handle this problem from specific angles, our solution proposes a new approach that provides real-time routing with the awareness of the expectations of multiple stakeholders in the ecosystem. For this purpose, we develop a Mixed Integer Programming (MIP) model that minimizes unmet demand and workforce requirements simultaneously to meet platform and courier expectations while maintaining the timeliness of the operation to meet restaurant and customer expectations. Since the model requires more time to provide good results for even small-size problems, we develop a multi-step algorithmic approach supported by strategies that hold or dissolve a part of the solutions to create opportunities for better results. A framework for agent-based simulation was created to implement the strategies and the algorithmic steps, accurately mimicking the operations and movements of couriers. The effectiveness of this solution was evaluated through experiments based on a real-world case study. The results indicate that our solution can generate high-quality results in a short time across various configurations, which are defined by different demand and supply patterns and varying problem sizes. Full article
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23 pages, 6268 KB  
Article
Investigation of Sediment Erosion of the Top Cover in the Francis Turbine Guide Vanes at the Genda Power Station
by Xudong Lu, Kang Xu, Tianlin Li, Yu Xiao, Kailiang Hu, Yaogang Xu and Xiaobing Liu
J. Mar. Sci. Eng. 2025, 13(10), 1923; https://doi.org/10.3390/jmse13101923 - 7 Oct 2025
Viewed by 215
Abstract
This study utilizes the Standard k-ε turbulence model and ANSYS CFX software to tackle silt erosion in the top cover clearances of guide vane of the Francis turbine at Genda Power Station (Minjiang River Basin section, 103°17′ E and 31°06′ N) [...] Read more.
This study utilizes the Standard k-ε turbulence model and ANSYS CFX software to tackle silt erosion in the top cover clearances of guide vane of the Francis turbine at Genda Power Station (Minjiang River Basin section, 103°17′ E and 31°06′ N) under sediment-laden flow conditions. A numerical simulation of a solid–liquid two-phase flow along the whole flow route was performed under rated operating circumstances to examine the impact of varying guide vane end clearance heights (0.3 mm, 0.5 mm, and 1.0 mm) on internal flow patterns and sediment erosion characteristics. The simulation parameters employed an average sediment concentration of 2.9 kg/m3 and a median particle size of 0.058 mm, indicative of the flood season. The findings demonstrate that augmenting the clearance height intensifies leaky flow and secondary flow, resulting in a 0.49% reduction in efficiency. As the gap expanded from 0.3 mm to 1.0 mm, the leakage flow velocity notably increased to 40 m/s, exacerbating flow separation, enlarging the vortex structures in the vaneless space, and augmenting the sediment velocity gradient and concentration, consequently heightening the risk of erosion. An experimental setup was devised based on the numerical results, and the dynamic resemblance between the constructed test section and the prototype turbine was confirmed for flow velocity, concentration, and Reynolds number. Tests on sediment erosion revealed that the erosion resistance of the anti-sediment erosion material 04Cr13Ni5Mo markedly exceeded that of the base cast steel, especially in high-velocity areas. This study delivers a systematic, quantitative analysis of clearance effects on flow and erosion, along with an experimental wear model specifically for the Gengda Power Station, thereby providing direct theoretical support and engineering guidance for its wear protection strategy and maintenance planning. Full article
(This article belongs to the Section Ocean Engineering)
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35 pages, 12616 KB  
Article
Route Planning for Unmanned Maize Detasseling Vehicle Based on a Dual-Route and Dual-Mode Adaptive Ant Colony Optimization
by Yu Wang, Yanhui Yang, Yichen Zhang, Lianqi Guo and Longhai Li
Agriculture 2025, 15(19), 2062; https://doi.org/10.3390/agriculture15192062 - 30 Sep 2025
Viewed by 283
Abstract
Maize is crucial for food, feed, and industrial materials. The seed purity directly affects yield and quality. Advancements in automation have led to the lightweight unmanned maize detasseling vehicle (UDV). To boost UDV’s efficiency, this paper proposes a dual-route and dual-mode adaptive ant [...] Read more.
Maize is crucial for food, feed, and industrial materials. The seed purity directly affects yield and quality. Advancements in automation have led to the lightweight unmanned maize detasseling vehicle (UDV). To boost UDV’s efficiency, this paper proposes a dual-route and dual-mode adaptive ant colony optimization (DRDM-AACO) for the detasseling route planning in maize seed production fields with hybrid spatial constraints. A mathematical model is established based on a proposed projection method for male flower nodes. To improve the performance of the ACO, four innovative mechanisms are proposed: a dual-route preference based on the dynamic selection strategy to ensure the integrity of the route topology; a dynamic candidate set with the variable neighborhood search strategy to balance exploration and exploitation; a non-uniform initial pheromone allocation based on the principle of intra-row priority and inter-row inhibition, and direction-constrained adaptive dual-mode pheromone regulation through local penalty and global evaporation strategies to reduce intra-row turnback routes. Comparative experiments showed DRDM-AACO reduced the route by 6.2% compared to ACO variants, verifying its effectiveness. Finally, experiments with various sizes and actual farmland compared DRDM-AACO to other various algorithms. The route was shortened by 32%, confirming its practicality and superiority. Full article
(This article belongs to the Section Artificial Intelligence and Digital Agriculture)
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20 pages, 7202 KB  
Article
A Novel Sorting Route Planning Method for Irregular Sheet Parts in the Shipbuilding Process
by Hongyan Xing, Cheng Luo, Jichao Song and Yansong Zhang
J. Mar. Sci. Eng. 2025, 13(10), 1871; https://doi.org/10.3390/jmse13101871 - 27 Sep 2025
Viewed by 236
Abstract
Due to the complexity of shipyards’ operating scenes and the inconsistency of ship parts’ type and size, current sorting operations for ship parts mainly rely on laborers, resulting in weak control over the production process and key nodes. With the gradual advancement of [...] Read more.
Due to the complexity of shipyards’ operating scenes and the inconsistency of ship parts’ type and size, current sorting operations for ship parts mainly rely on laborers, resulting in weak control over the production process and key nodes. With the gradual advancement of intelligent manufacturing technology in the shipbuilding process, the trend of machines replacing humans is obvious. In order to promote the automation of the sorting process, intelligent scene recognition and route planning algorithms are needed. In this work, we introduce a localization method based on a laser line profile sensor and ship parts layout analysis algorithm, aiming at obtaining the information needed for sorting route planning. In addition, a heuristic-based route planning algorithm is proposed to solve the built mathematical model of the ship part sorting process. The proposed method can optimize the sorting order of parts, realize stable stacking, shorten sorting distance (taking about 490 m for 43 parts), and thereby improve operation efficiency. These results show that the proposed approach can make intelligent and comprehensible sorting route planning for the ship parts layout. Full article
(This article belongs to the Section Ocean Engineering)
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20 pages, 5035 KB  
Article
Effect of Small Deformations on Optimisation of Final Crystallographic Texture and Microstructure in Non-Oriented FeSi Steels
by Ivan Petrišinec, Marcela Motýľová, František Kováč, Ladislav Falat, Viktor Puchý, Mária Podobová and František Kromka
Crystals 2025, 15(10), 839; https://doi.org/10.3390/cryst15100839 - 26 Sep 2025
Viewed by 167
Abstract
Improving the isotropic magnetic properties of FeSi electrical steels has traditionally focused on enhancing their crystallographic texture and microstructural morphology. Strengthening the cube texture within a ferritic matrix of optimal grain size is known to reduce core losses and increase magnetic induction. However, [...] Read more.
Improving the isotropic magnetic properties of FeSi electrical steels has traditionally focused on enhancing their crystallographic texture and microstructural morphology. Strengthening the cube texture within a ferritic matrix of optimal grain size is known to reduce core losses and increase magnetic induction. However, conventional cold rolling followed by annealing remains insufficient to optimise the magnetic performance of thin FeSi strips fully. This study explores an alternative approach based on grain boundary migration driven by temperature gradients combined with deformation gradients, either across the sheet thickness or between neighbouring grains, in thin, weakly deformed non-oriented (NO) electrical steel sheets. The concept relies on deformation-induced grain growth supported by rapid heat transport to promote the preferential formation of coarse grains with favourable orientations. Experimental material consisted of vacuum-degassed FeSi steel with low silicon content. Controlled deformation was introduced by temper rolling at room temperature with 2–40% thickness reductions, followed by rapid recrystallisation annealing at 950 °C. Microstructure, texture, and residual strain distributions were analysed using inverse pole figure (IPF) maps, kernel average misorientation (KAM) maps, and orientation distribution function (ODF) sections derived from electron backscattered diffraction (EBSD) data. This combined thermomechanical treatment produced coarse-grained microstructures with an enhanced cube texture component, reducing coercivity from 162 A/m to 65 A/m. These results demonstrate that temper rolling combined with dynamic annealing can surpass the limitations of conventional processing routes for NO FeSi steels. Full article
(This article belongs to the Special Issue Microstructure and Deformation of Advanced Alloys (2nd Edition))
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15 pages, 3956 KB  
Article
Novel Alloy Designed Electrical Steel for Improved Performance in High-Frequency Electric Machines
by Carl Slater, Xiyun Ma, Gwendal Lagorce, Juliette Soulard and Claire Davis
Metals 2025, 15(10), 1066; https://doi.org/10.3390/met15101066 - 23 Sep 2025
Viewed by 321
Abstract
The increase in electrification and desire for greater electrical motor efficiency under a range of operating conditions for different products (e.g., household appliances, automotive and aerospace) is driving innovative motor designs and demands for higher performing electrical steels. Improvements in the magnetic, electrical [...] Read more.
The increase in electrification and desire for greater electrical motor efficiency under a range of operating conditions for different products (e.g., household appliances, automotive and aerospace) is driving innovative motor designs and demands for higher performing electrical steels. Improvements in the magnetic, electrical and/or mechanical properties of electrical steels are required for high-volume electric motors and recent advances include steels with increased silicon (Si) content (from <3.5 wt% Si up to 6.5 wt%). Whilst the 6.5 wt% Si steels provide increased motor performance at high frequencies, the formation of a brittle BCC B2/D03 phase means that they cannot be cold-rolled, and therefore the production route involves siliconization after the required thickness strip is produced. The advances in computationally driven alloy design, coupled with physical metallurgical understanding, allow for more adventurous alloy design for electrical steels, outside the traditional predominantly Fe-Si compositional space. Two alloys representing a new alloy family called HiPPES (High-Performing and Processable Electrical Steel), based on low cost commonly used steel alloying elements, have been developed, cast, rolled, heat-treated, and both magnetically and mechanically tested. These alloys (with nominal compositions of Fe-3.2Mn-3.61Si-0.63Ni-0.75Cr-0.15Al-0.4Mo and Fe-2Mn-4.5Si-0.4Ni-0.75Cr-0.09Al) offer improvements compared to current ≈3 wt% Si grades: in magnetic performance (>25% magnetic loss reduction at >1 kHz), and in tensile strength (>33% increase in tensile strength with similar elongation value). Most importantly, they are maintaining processability to allow for full-scale commercial production using traditional continuous casting, hot and cold rolling, and annealing. The new alloys also showed improved resilience to grain size, with the HiPPES materials showing a <5% variance in loss at frequencies greater than 400 Hz for grain sizes between 55 and 180 µm. Comparatively, a commercial M250-35A material showed a 40% increase in loss for the same range. The paper reports on the alloy design approach used, the microstructures, and the mechanical, electrical and magnetic properties of the developed novel electrical steels compared to conventional ≈3 wt% Si and 6.5 wt% Si material. Full article
(This article belongs to the Special Issue Electrical Steels)
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39 pages, 4595 KB  
Review
Recent Advances in Metal Nanoclusters: From Novel Synthesis to Emerging Applications
by Alexandru-Milentie Hada, Marc Lamy de la Chapelle, Monica Focsan and Simion Astilean
Molecules 2025, 30(19), 3848; https://doi.org/10.3390/molecules30193848 - 23 Sep 2025
Viewed by 629
Abstract
Metallic nanoclusters (NCs), composed of a few to a hundred atoms, occupy a unique space between molecules and nanoparticles, exhibiting discrete electronic states, strong photoluminescence, and size-dependent catalytic activity. Their ultrasmall cores (<3 nm) and ligand-controlled surfaces confer tunable optical, electronic, and catalytic [...] Read more.
Metallic nanoclusters (NCs), composed of a few to a hundred atoms, occupy a unique space between molecules and nanoparticles, exhibiting discrete electronic states, strong photoluminescence, and size-dependent catalytic activity. Their ultrasmall cores (<3 nm) and ligand-controlled surfaces confer tunable optical, electronic, and catalytic properties, making them attractive for diverse applications. In recent years, significant progress has been made toward developing faster, more reproducible, and scalable synthesis routes beyond classical wet-chemical reduction. Emerging strategies such as microwave-, photochemical-, sonochemical-, and catalytically assisted syntheses, together with smart, automation-driven platforms, have improved efficiency, structural control, and environmental compatibility. These advances have accelerated the deployment of NCs in imaging, sensing, and catalysis. Near-infrared emitting NCs enable deep-tissue, high-contrast fluorescence imaging, while theranostic platforms combine diagnostic precision with photothermal or photodynamic therapy, gene delivery, and anti-inflammatory treatment. NC-based sensors allow ultrasensitive detection of ions, small molecules, and pathogens, and atomically precise NCs have enabled efficient CO2 reduction, water splitting, and nitrogen fixation. Therefore, in this review, we highlight studies reported in the past five years on the synthesis and applications of metallic NCs, linking emerging methodologies to their functional potential in nanotechnology. Full article
(This article belongs to the Special Issue Metallic Nanoclusters and Their Interaction with Light)
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22 pages, 4329 KB  
Article
Fractal-Based Approach to Simultaneous Layout Routing and Pipe Sizing of Water Supply Networks
by Paweł Suchorab, Dariusz Kowalski and Małgorzata Iwanek
Water 2025, 17(18), 2745; https://doi.org/10.3390/w17182745 - 17 Sep 2025
Viewed by 400
Abstract
The process of designing water distribution networks is divided into two main stages: network layout routing and pipe sizing. However, routing and sizing are not separate tasks—the shape of the network affects the diameters of the pipes, and vice versa. This paper presents [...] Read more.
The process of designing water distribution networks is divided into two main stages: network layout routing and pipe sizing. However, routing and sizing are not separate tasks—the shape of the network affects the diameters of the pipes, and vice versa. This paper presents an innovative fractal-based method, which enables the simultaneous layout routing and pipe sizing of water supply networks. The developed pipe routes and diameters selected according to the method are mathematically justified; the selection considers the total length of the pipes, the number of rotation angles of the base section, the cost of the water supply system construction and the priority of water supply to individual customers. The novelty of the method lies in the possibility of carrying out the processes of routing and sizing of the network in a recursive manner by the adoption of the principles of fractal geometry and Murray’s law. The method was tested under the conditions of a synthetic settlement. The obtained results enable us to conclude that the method is universal and suitable for shaping water supply networks, while determining the pipes’ diameters, both under the conditions of a single- and multi-sided water supply source. Full article
(This article belongs to the Special Issue Advances in Management and Optimization of Urban Water Networks)
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13 pages, 4625 KB  
Article
Formulation, Optimization, and Evaluation of Transferosomes Co-Loaded with Methotrexate and Sorafenib for Anti-Arthritic Activity
by Muhammad Adnan, Lateef Ahmad, Muhammad Junaid Dar, Humzah Jamshaid, Muhammad Noman and Muhammad Faheem
Pharmaceutics 2025, 17(9), 1196; https://doi.org/10.3390/pharmaceutics17091196 - 15 Sep 2025
Viewed by 428
Abstract
Purpose: This study was designed to develop a nanoparticle-based methotrexate (MTX) and sorafenib (SRF)-loaded transferosome (MTX-SRF-TFS) for effective management of arthritis through the transdermal route. Methods: For the preparation of MTX-SRF-TFS, the thin-film hydration technique was selected and optimized using Box–Behnken Design. The [...] Read more.
Purpose: This study was designed to develop a nanoparticle-based methotrexate (MTX) and sorafenib (SRF)-loaded transferosome (MTX-SRF-TFS) for effective management of arthritis through the transdermal route. Methods: For the preparation of MTX-SRF-TFS, the thin-film hydration technique was selected and optimized using Box–Behnken Design. The particle size of the nanoparticles was determined using a Malvern Zeta sizer and electron microscopy. An in vivo skin retention and penetration study was also conducted to evaluate the designed delivery system. Furthermore, the therapeutic response of MTX-SRF-TFS was determined using the CFA-induced mouse model. Results: The optimized MTX-SRF-TFS formulation (F4), having an average particle size (PS) of 162.20 ± 2.89 nm and percent entrapment efficiency (%EE) of MTX and SRF of 92.16 ± 4.95 and 81.54 ± 3.23, respectively, was selected for further assessment. Due to the deformable nature of MTX-SRF-TFS, MTX and SRF penetrate more deeply into the cutaneous layers, exhibiting an enhanced transdermal effect, as shown by the results of ex vivo skin permeation and retention studies. Furthermore, in vivo anti-arthritic studies have shown the superior pharmacodynamic response of MTX and SRF when incorporated into transferosomes, as it caused a marked reduction in arthritic score and paw diameter in CFA-induced arthritis in BALB/c mice. Histopathology analysis and X-ray radiography also confirmed the findings that MTX-SRF-TFS has improved anti-arthritic response in contrast to plain MTX-SRF gel. Conclusions: The MTX-SRF-TFS is highly effective in managing CFA-induced arthritis, and the designed delivery system should be further evaluated on pharmacokinetic grounds to progress towards clinical studies. Full article
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22 pages, 7884 KB  
Article
Ball Milling–Alkali Synergy: Mechanochemical Degradation of Phenolic Resin and Its Impact on the Performance Evolution of Rock Wool-Based Alkali-Activated Cementitious Composites
by Xu Gao, Xiaomin Zhang, Chang Chen, Xuan Liu, Jiaqi Zhu, Shaowu Jiu, Qiang Song and Yanxin Chen
Buildings 2025, 15(18), 3303; https://doi.org/10.3390/buildings15183303 - 12 Sep 2025
Viewed by 492
Abstract
Rock wool trim waste (RWTW) presents considerable recycling difficulties due to the release of toxic volatiles from phenolic resin binders during pyrolysis, which also hinders its effective utilization in rock wool-based alkali-activated cementitious composites (RWACCs). Traditional thermal and chemical resin removal approaches are [...] Read more.
Rock wool trim waste (RWTW) presents considerable recycling difficulties due to the release of toxic volatiles from phenolic resin binders during pyrolysis, which also hinders its effective utilization in rock wool-based alkali-activated cementitious composites (RWACCs). Traditional thermal and chemical resin removal approaches are energy-consuming, produce secondary pollutants, and can diminish the aluminosilicate reactivity of RWTW. This study introduces an innovative mechanochemical ball milling pretreatment aimed at selectively breaking resin C−O bonds while maintaining the integrity of the mineral phase, thus facilitating eco-friendly and efficient RWTW recycling. By applying different milling durations (30–120 min), the properties of RWTW particles were systematically characterized through granulometry, XRD, SEM, and FT-IR. The hydration kinetics, compressive strength, and microstructure of RWACC pastes were thoroughly examined. Key findings confirm that 120 min is the optimum ball milling duration, as validated by weighted sum analysis. This duration yielded a median particle size (D50) of 7.15 μm, significantly increased reactivity (evidenced by a 28-day activity index of 85.3%), and outstanding mechanical properties, achieving flexural and compressive strengths of 15.73 MPa and 97.27 MPa, respectively. The mechanochemical process successfully encapsulated organic residues within the geopolymer matrix, preventing toxic emissions. This synergistic approach between resin degradation and enhanced reactivity demonstrates a viable route for the industrial-scale valorization of RWTW. It significantly contributes to the circular economy objectives in the construction sector. Full article
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39 pages, 1281 KB  
Article
Sustainable Metaheuristic-Based Planning of Rural Medium- Voltage Grids: A Comparative Study of Spanning and Steiner Tree Topologies for Cost-Efficient Electrification
by Lina María Riaño-Enciso, Brandon Cortés-Caicedo, Oscar Danilo Montoya, Luis Fernando Grisales-Noreña and Jesús C. Hernández
Sustainability 2025, 17(18), 8145; https://doi.org/10.3390/su17188145 - 10 Sep 2025
Viewed by 348
Abstract
This paper presents a heuristic methodology for the optimal expansion of unbalanced three-phase distribution systems in rural areas, simultaneously addressing feeder routing and conductor sizing to minimize the total annualized cost—defined as the sum of investments in conductors and operational energy losses. The [...] Read more.
This paper presents a heuristic methodology for the optimal expansion of unbalanced three-phase distribution systems in rural areas, simultaneously addressing feeder routing and conductor sizing to minimize the total annualized cost—defined as the sum of investments in conductors and operational energy losses. The planning strategy explores two radial topological models: the Minimum Spanning Tree (MST) and the Steiner Tree (ST). The latter incorporates auxiliary nodes to reduce the total line length. For each topology, an initial conductor sizing is performed based on three-phase power flow calculations using Broyden’s method, capturing the unbalanced nature of the rural networks. These initial solutions are refined via four metaheuristic algorithms—the Chu–Beasley Genetic Algorithm (CBGA), Particle Swarm Optimization (PSO), the Sine–Cosine Algorithm (SCA), and the Grey Wolf Optimizer (GWO)—under a master–slave optimization framework. Numerical experiments on 15-, 25- and 50-node rural test systems show that the ST combined with GWO consistently achieves the lowest total costs—reducing expenditures by up to 70.63% compared to MST configurations—and exhibits superior robustness across all performance metrics, including best-, average-, and worst-case solutions, as well as standard deviation. Beyond its technical contributions, the proposed methodology supports the United Nations Sustainable Development Goals by promoting universal energy access (SDG 7), fostering cost-effective rural infrastructure (SDG 9), and contributing to reductions in urban–rural inequalities in electricity access (SDG 10). All simulations were implemented in MATLAB 2024a, demonstrating the practical viability and scalability of the method for planning rural distribution networks under unbalanced load conditions. Full article
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19 pages, 18634 KB  
Article
Microstructure and Mechanical Properties of Al6060/TiB2 Aluminum Matrix Composites Produced via Ultrasonically Assisted Stir Casting and Radial-Shear Rolling
by Maxat Abishkenov, Ilgar Tavshanov, Nikita Lutchenko, Kairosh Nogayev, Zhassulan Ashkeyev and Siman Kulidan
J. Manuf. Mater. Process. 2025, 9(9), 309; https://doi.org/10.3390/jmmp9090309 - 9 Sep 2025
Cited by 1 | Viewed by 532
Abstract
Lightweight aluminum matrix composites with superior strength and structural integrity are in high demand for next-generation transportation and aerospace applications. In this work, Al6060-based composites reinforced with ≈2 wt.% TiB2 were produced using a hybrid processing route that combines ultrasonically assisted stir [...] Read more.
Lightweight aluminum matrix composites with superior strength and structural integrity are in high demand for next-generation transportation and aerospace applications. In this work, Al6060-based composites reinforced with ≈2 wt.% TiB2 were produced using a hybrid processing route that combines ultrasonically assisted stir casting with radial-shear rolling (RSR). This strategy enabled uniform particle dispersion, strong matrix–reinforcement bonding, and substantial microstructural refinement (grain size 4–6 μm) with reduced porosity. Consequently, the Al6060/TiB2 composites demonstrated substantial gains over the as-cast alloy, combining a yield strength of 108.6 MPa, ultimate tensile strength of 156.9 MPa, and microhardness of 76.3 HV0.2 with a balanced ductility of ~9%. The demonstrated synergy of ultrasound-assisted casting and severe plastic deformation highlights a scalable pathway for fabricating high-performance aluminum composites, positioning them as promising candidates for aerospace, automotive, and other advanced engineering sectors. Full article
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15 pages, 2172 KB  
Communication
Triangulating Timing, Tropism and Burden of Sarcoma Metastases: Toward Precision Surveillance and Therapy in a Real-World-Time Cohort
by Philip Heesen, Dario Feusi, Bettina Vogel, Gabriela Studer, Bruno Fuchs and on behalf of the Swiss Sarcoma Network
Cancers 2025, 17(18), 2944; https://doi.org/10.3390/cancers17182944 - 9 Sep 2025
Viewed by 416
Abstract
Background: Sarcoma surveillance guidelines still apply uniform imaging intervals based on tumor grade and stage that ignore histotype-specific metastatic behavior. We prospectively analyzed metastatic timing, organ tropism, and lesion burden across a real-world sarcoma cohort to generate an evidence base for risk-adapted [...] Read more.
Background: Sarcoma surveillance guidelines still apply uniform imaging intervals based on tumor grade and stage that ignore histotype-specific metastatic behavior. We prospectively analyzed metastatic timing, organ tropism, and lesion burden across a real-world sarcoma cohort to generate an evidence base for risk-adapted follow-up and treatment stratification. Methods: In a prospective multicenter study, 1850 patients with suspected sarcoma were screened. SHAPEHub, a real-world-time data warehouse, captured clinicopathological variables and imaging. Adults with histologically confirmed soft-tissue or bone sarcoma (n = 295) formed the analytic cohort. Metastases were classified as synchronous (≤6 months) or metachronous (>6 months), lung-only versus multi-organ, and oligometastatic (≤5 lesions, ≤2 organs) versus polymetastatic. TTME was illustrated with Kaplan–Meier curves for the full cohort (descriptive); where subgroup comparisons are shown, log-rank tests are reported. Results: Ninety-three patients (31.5%) developed metastases after a median follow-up of 20.9 months. Metastatic risk was front-loaded: 36.6% were synchronous, and 67.8% of metachronous events occurred within year 1. The lung was the initial site in 62.4% of events, bone in 18.3%, and liver in 11.8%. Half of the lung-metastatic patients remained pulmonary-confined; the remainder followed a multi-organ route involving bone and lymph nodes. Oligometastatic spread predominated in the lung-only subgroup (61%) versus multi-organ (28%). Histotype influenced both timing and tropism: angiosarcoma and Ewing sarcoma metastasized earliest (median 3.7 and 5.0 months) and multi-organ; leiomyosarcoma and UPS were lung-dominant; Ewing sarcoma and epithelioid haemangioendothelioma were bone-tropic; and angiosarcoma was liver-tropic. Conclusions: Metastatic sarcoma displays three intersecting dimensions—early versus late onset, organ-specific tropism, and oligo- versus polymetastatic burden—none of which are addressed by the current “one-size-fits-all” surveillance. Recognizing these patterns delineates windows for tailored imaging and stratified therapy selection (e.g., local ablation for oligometastatic lung disease, intensified systemic regimens for early, polymetastatic spread). These findings lay the groundwork for precision-adapted surveillance and treatment protocols. Pattern-stratified trials and health-economic evaluations are now needed to assess whether this approach improves outcomes and optimizes resource allocation. Full article
(This article belongs to the Section Methods and Technologies Development)
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18 pages, 1210 KB  
Article
Towards Green and Smart Ro–Ro Port Terminal Operations: A Comparative Analysis of ICE, BET and e-AGT Tractors
by Caterina Malandri, Luca Mantecchini and Filippo Paganelli
Future Transp. 2025, 5(3), 121; https://doi.org/10.3390/futuretransp5030121 - 8 Sep 2025
Viewed by 463
Abstract
The decarbonization and automation of port operations are emerging as key strategies to enhance the sustainability and efficiency of maritime logistics. This study proposes a simulation-based framework to assess the operational and environmental impacts of transitioning from traditional Internal Combustion Engine (ICE) tractors [...] Read more.
The decarbonization and automation of port operations are emerging as key strategies to enhance the sustainability and efficiency of maritime logistics. This study proposes a simulation-based framework to assess the operational and environmental impacts of transitioning from traditional Internal Combustion Engine (ICE) tractors to Battery Electric Tractors (BET) and Automated Electric Guided Tractors (e-AGT) in Roll-on/Roll-off (Ro–Ro) port terminal operations. The proposed framework is applied to simulate a full vessel turnaround at the Ro–Ro terminal of the Port of Ravenna (Italy). A set of Key Performance Indicators (KPIs) is defined to evaluate turnaround time, vehicle productivity, energy consumption and CO2 emissions across three scenarios. The results indicate that both BET and e-AGT configurations significantly reduce emissions compared to ICE, with reductions up to 40%. However, the e-AGT scenario reveals operational drawbacks, including increased unloading time and reduced fleet availability due to charging constraints and routing limitations. These findings highlight the environmental potential of automation and electrification but also emphasize the need for integrated planning of fleet size, charging infrastructure and circulation specifications. The proposed framework provides a replicable decision-support tool for port authorities and logistics operators to evaluate alternative handling technologies under realistic conditions. Full article
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