Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (49)

Search Parameters:
Keywords = standing lateral radiograph

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
12 pages, 281 KB  
Article
Brace Treatment Is Associated with Lower Curve Progression in Moderate Adolescent Idiopathic Scoliosis, While Psychosocial Outcomes Are Driven by Depressive Symptoms and Curve Progression
by Ahmet Keskin, Niyazi Igde, Mustafa Serpi, Gorkem Kayis, Huseyin Sina Coskun and Mehmet Akif Kaygusuz
J. Clin. Med. 2026, 15(6), 2375; https://doi.org/10.3390/jcm15062375 - 20 Mar 2026
Viewed by 406
Abstract
Background: The impact of thoracolumbosacral orthosis (TLSO) bracing on sagittal spinopelvic alignment and psychosocial outcomes in adolescent idiopathic scoliosis (AIS) remains debated. Methods: This retrospective comparative study included 120 girls (10–18 years) with AIS (baseline Cobb angle 20–40°) and skeletal immaturity (Risser 0–1). [...] Read more.
Background: The impact of thoracolumbosacral orthosis (TLSO) bracing on sagittal spinopelvic alignment and psychosocial outcomes in adolescent idiopathic scoliosis (AIS) remains debated. Methods: This retrospective comparative study included 120 girls (10–18 years) with AIS (baseline Cobb angle 20–40°) and skeletal immaturity (Risser 0–1). Patients were managed with a thoracolumbosacral orthosis (TLSO) brace (n = 60) or observation alone (n = 60). Standing posteroanterior and lateral full-spine radiographs were obtained at baseline and at 24 ± 6 months; follow-up radiographs were acquired out of brace after a standardized 48 h brace-free interval. They were used to measure coronal and sagittal spinopelvic parameters. Patient-reported outcomes included the Scoliosis Research Society-22r (SRS-22r), Pediatric Quality of Life Inventory (PedsQL), Spinal Appearance Questionnaire (SAQ), Trunk Appearance Perception Scale (TAPS), and Beck Depression Inventory (BDI). The primary endpoint was curve progression (≥5° increase or exceeding 40°) at 24 months. Multivariable regression was used to adjust for baseline Cobb angle and maturity. Mean follow-up was 24 ± 6 months. Results: Mean Cobb change was +1.2° in the brace group vs. +7.3° in the observation group (group × time interaction p < 0.001). Progression (≥5°) occurred in 15% vs. 45%, respectively, and 18% of observed patients exceeded 40° (risk ratio 0.33, 95% CI 0.17–0.65; number needed to treat 4, 95% CI 3–7). Sagittal spinopelvic parameters showed no significant group-by-time interaction. No significant between-group differences were observed in SRS-22r, PedsQL, SAQ, TAPS, or BDI at baseline or follow-up. Patients with curve progression exhibited worse appearance-related scores. In multivariable analysis, depressive symptoms were the strongest determinant of PedsQL (β = −0.55, p < 0.001). Conclusions: Brace treatment was associated with reduced curve progression in girls with moderate AIS. Over approximately two years of follow-up, we did not observe clinically relevant between-group differences in sagittal spinopelvic alignment or psychosocial patient-reported outcomes. Given the retrospective, non-randomized design and self-reported adherence, psychosocial findings should be interpreted cautiously and require confirmation in prospective, objectively monitored, psychologically informed bracing studies. Full article
(This article belongs to the Section Orthopedics)
10 pages, 2547 KB  
Case Report
Total Ankle Replacement Through a Lateral Transfibular Approach in Patients with Ipsilateral Knee Arthrodesis: Report of Two Cases
by Carla Carfì, Serban-Andrei Constantinescu, Cristian Indino, Federico Della Rocca, Camilla Maccario and Federico Giuseppe Usuelli
J. Clin. Med. 2026, 15(6), 2094; https://doi.org/10.3390/jcm15062094 - 10 Mar 2026
Viewed by 282
Abstract
Background: Knee arthrodesis markedly alters lower limb biomechanics and creates a challenging scenario when associated with end-stage ankle osteoarthritis. No prior reports have specifically described treatment with total ankle replacement (TAR) in the presence of an ipsilateral fused knee. This study evaluated [...] Read more.
Background: Knee arthrodesis markedly alters lower limb biomechanics and creates a challenging scenario when associated with end-stage ankle osteoarthritis. No prior reports have specifically described treatment with total ankle replacement (TAR) in the presence of an ipsilateral fused knee. This study evaluated the feasibility and mid-term outcomes of TAR in this rare condition. Methods: Two patients with post-traumatic end-stage ankle osteoarthritis and long-standing knee arthrodesis underwent TAR using a lateral transfibular approach with a Zimmer Trabecular Metal™ implant. Surgical planning aimed to restore coronal and sagittal alignment. Postoperative management and rehabilitation were specifically adapted to the absence of knee motion, with emphasis on gait re-education. Clinical and radiographic follow-up was performed up to 36 months. Results: At final follow-up, both patients showed substantial pain reduction, improved ankle range of motion, and recovery of a stable, functional gait compatible with knee fusion. Imaging demonstrated well-aligned, stable components without loosening or subsidence. No major complications or reoperations occurred. Conclusions: Lateral transfibular TAR appears feasible and effective for end-stage ankle osteoarthritis in patients with ipsilateral knee arthrodesis, preserving ankle motion and supporting functional ambulation in this complex setting. Full article
(This article belongs to the Section Orthopedics)
Show Figures

Figure 1

12 pages, 486 KB  
Article
The Relationship Between Calcaneal Bump Height and Progressive Collapsing Foot Deformity on Weight-Bearing Lateral Radiographs: Cross-Sectional Study in Adult Males
by Hulya Cetin Tuncez, Selin Eroglu, Mahmut Tuncez and Zehra Hilal Adibelli
Diagnostics 2026, 16(5), 745; https://doi.org/10.3390/diagnostics16050745 - 2 Mar 2026
Viewed by 419
Abstract
Objectives: To investigate the association between calcaneal bump height and hindfoot radiographic parameters on weight-bearing lateral radiographs in adult males with Progressive Collapsing Foot Deformity (PCFD), and to determine whether posterior calcaneal morphology differs between feet with and without PCFD-related flatfoot alignment. Materials: [...] Read more.
Objectives: To investigate the association between calcaneal bump height and hindfoot radiographic parameters on weight-bearing lateral radiographs in adult males with Progressive Collapsing Foot Deformity (PCFD), and to determine whether posterior calcaneal morphology differs between feet with and without PCFD-related flatfoot alignment. Materials: We retrospectively reviewed 583 men (1166 feet), aged 17–46 years, who underwent standing weight-bearing lateral foot radiographs between 1 January 2024 and 31 August 2025. Radiographic measurements included calcaneal pitch, Meary’s angle, navicular height, tibiocalcaneal angle, Böhler’s angle, Fowler–Philip angle, calcaneal bump height, and additional calcaneal morphological indices. A flatfoot alignment consistent with PCFD was defined as a calcaneal pitch < 18°. Receiver operating characteristic (ROC) analysis and multivariable logistic regression were performed to assess diagnostic performance and identify parameters independently associated with flatfoot alignment. Results: Flatfoot alignment was identified in 232 feet (19.9%) from 153 patients (26.2%). Compared with normally aligned feet, the flatfoot group demonstrated significantly lower navicular height, calcaneal bump height, and Böhler’s angle, along with higher tibiocalcaneal and Meary’s angles (all p < 0.001). ROC analysis showed navicular height to be the most accurate diagnostic parameter (AUC = 0.75), followed by the tibiocalcaneal angle (AUC = 0.69). Multivariable logistic regression revealed that navicular height ≤ 52.7 mm, tibiocalcaneal angle > 64.6°, Böhler’s angle ≤ 32.9°, Meary’s angle > 4.9°, calcaneal bump height ≤ 3.9 mm, and Fowler–Philip angle > 61.1° were independently associated with flatfoot alignment (Nagelkerke R2 = 0.293, p < 0.001). Conclusions: Calcaneal bump height is reduced in PCFD and reflects posterior calcaneal remodelling associated with hindfoot malalignment and medial arch collapse. Although not a primary diagnostic parameter, calcaneal bump height provides complementary morphological information that may inform surgical planning and osteotomy strategy aimed at restoring physiologic hindfoot biomechanics and Achilles tendon loading in patients with PCFD. Full article
(This article belongs to the Section Clinical Diagnosis and Prognosis)
Show Figures

Figure 1

24 pages, 6419 KB  
Case Report
Improvement After Hardware Removal in Post-Fusion Adult AIS: A Unique 35-Year Case Study Using Schroth-Based Physiotherapy and Bracing
by Josée Boucher, Andrea Lebel, Dat Nhut Nguyen, Stéphanie Jacques, Jacques Charest, Sarah Shidler, Carole Chebaro, Chun Han Huang, Nadina Adulovic and Jacob Carberry
Healthcare 2026, 14(1), 43; https://doi.org/10.3390/healthcare14010043 - 24 Dec 2025
Cited by 1 | Viewed by 2964
Abstract
Background: Adult scoliosis following spinal fusion and subsequent hardware removal presents complex challenges, especially when deformity progresses in both the sagittal and coronal planes. Revision surgery is often recommended but it entails considerable risks. Conservative approaches, including Schroth-based physiotherapy and bracing, offer promising [...] Read more.
Background: Adult scoliosis following spinal fusion and subsequent hardware removal presents complex challenges, especially when deformity progresses in both the sagittal and coronal planes. Revision surgery is often recommended but it entails considerable risks. Conservative approaches, including Schroth-based physiotherapy and bracing, offer promising alternatives for select patients, particularly older adults with comorbidities or those who decline further surgery. Case Presentation: A woman with adolescent idiopathic scoliosis (diagnosed at age 13) underwent spinal fusion with Harrington rod instrumentation and costoplasty at age 24. She was de-instrumented two years later due to infection and developed progressive thoracic hyperkyphosis, coronal imbalance, and 12 cm loss of height over two decades. At age 47, she chose conservative management instead of revision surgery. Methods: She completed a 28-month program combining Schroth-based physiotherapy supervised by a certified therapist and part-time bracing. Outcomes included radiographs, inclinometry, spirometry, spinal-muscle ultrasound, height/posture measures, and SRS-22 and ODI scores. Results: Substantial clinical improvements were observed. Thoracic kyphosis decreased from 80° to 45° (44%) and the coronal thoracic curve was reduced from 48° to 32° (33%). Lumbar lordosis increased by 6°, standing height rose by 4 cm, and forced vital capacity improved by 900 mL (33%). The Oswestry Disability Index (ODI) score improved from 4% to 0%, and SRS-22 domains (pain, function, self-image, mental health, satisfaction) showed meaningful gains. The patient returned to full physical activity and avoided further surgery. Conclusion: This case highlights the potential of Schroth-based physiotherapy with bracing to reverse postural and functional decline in complex post-fusion scoliosis. It offers a viable non-surgical option when revision surgery poses a high risk or is declined and aligns with modern rehabilitative goals focused on long-term quality of life. Full article
Show Figures

Figure 1

26 pages, 4625 KB  
Article
Reliability of Large Language Model-Based Artificial Intelligence in AIS Assessment: Lenke Classification and Fusion-Level Suggestion
by Cemil Aktan, Akın Koşar, Melih Ünal, Murat Korkmaz, Özcan Kaya, Turgut Akgül and Ferhat Güler
Diagnostics 2025, 15(24), 3219; https://doi.org/10.3390/diagnostics15243219 - 16 Dec 2025
Viewed by 758
Abstract
Background: Accurate deformity classification and fusion-level planning are essential in adolescent idiopathic scoliosis (AIS) surgery and are traditionally guided by Cobb angle measurement and the Lenke system. Multimodal large language models (LLMs) (e.g., ChatGPT-4.0; Claude 3.7 Sonnet, Gemini 2.5 Pro, DeepSeek-R1-0528 Chat) are [...] Read more.
Background: Accurate deformity classification and fusion-level planning are essential in adolescent idiopathic scoliosis (AIS) surgery and are traditionally guided by Cobb angle measurement and the Lenke system. Multimodal large language models (LLMs) (e.g., ChatGPT-4.0; Claude 3.7 Sonnet, Gemini 2.5 Pro, DeepSeek-R1-0528 Chat) are increasingly used for image interpretation despite limited validation for radiographic decision-making. This study evaluated the agreement and reproducibility of contemporary multimodal LLMs for AIS assessment compared with expert spine surgeons. Methods: This single-center retrospective study included 125 AIS patients (94 females, 31 males; mean age 14.8 ± 1.9 years) who underwent posterior instrumentation (2020–2024). Two experienced spine surgeons independently performed Lenke classification (including lumbar and sagittal modifiers) and selected fusion levels (UIV–LIV) on standing AP, lateral, and side-bending radiographs; discrepancies were resolved by consensus to establish the reference standard. The same radiographs were analyzed by four paid multimodal LLMs using standardized zero-shot prompts. Because LLMs showed inconsistent end-vertebra selection, LLM-derived Cobb angles lacked a common anatomical reference frame and were excluded from quantitative analysis. Agreement with expert consensus and test–retest reproducibility (repeat analyses one week apart) were assessed using Cohen’s κ. Evaluation times were recorded. Results: Surgeon agreement was high for Lenke classification (92.0%, κ = 0.913) and fusion-level selection (88.8%, κ = 0.879). All LLMs demonstrated chance-level test–retest reproducibility and very low agreement with expert consensus (Lenke: 1.6–10.2%, κ = 0.001–0.036; fusion: 0.8–12.0%, κ = 0.003–0.053). Claude produced missing outputs in 17 Lenke and 29 fusion-level cases. Although LLMs completed assessments far faster than surgeons (seconds vs. ~11–12 min), speed did not translate into clinically acceptable reliability. Conclusions: Current general-purpose multimodal LLMs do not provide reliable Lenke classification or fusion-level planning in AIS. Their poor agreement with expert surgeons and marked internal inconsistency indicate that LLM-generated interpretations should not be used for surgical decision-making or patient self-assessment without task-specific validation. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Show Figures

Figure 1

14 pages, 2161 KB  
Article
Effects of Weight-Bearing-Induced Changes in Tibial Inclination Angle on Varus Thrust During Gait in Female Patients with Knee Osteoarthritis
by Ryosuke Karashima, Shintaro Kishimoto, Takuya Ibara, Kiyotaka Hada, Tatsuo Motoyama, Masayuki Kawashima, Yusuke Murofushi and Hiroshi Katoh
Biomechanics 2025, 5(4), 98; https://doi.org/10.3390/biomechanics5040098 - 1 Dec 2025
Viewed by 823
Abstract
Background: The relationship between varus thrust (VT) during gait and static limb alignment on radiography in knee osteoarthritis (OA) remains unclear. Therefore, the present study investigated the association between the tibial inclination angle (TA), which was noninvasively measured from the body surface, and [...] Read more.
Background: The relationship between varus thrust (VT) during gait and static limb alignment on radiography in knee osteoarthritis (OA) remains unclear. Therefore, the present study investigated the association between the tibial inclination angle (TA), which was noninvasively measured from the body surface, and radiographic parameters. In Addition, this study analyzed how TA changes under different loading conditions (ΔTA) relate to VT acceleration (VTA) during early stance using an inertial measurement unit (IMU) sensor. Methods: Nineteen female patients (mean age: 63.5 ± 8.6 years) with knee OA or medial meniscus injury were included. The TA was defined as the angle between the tibial mechanical axis and a vertical line from the floor, which was measured in standardized standing and supine positions. The ΔTA was calculated as the difference between these positions. To assess lower limb alignment, the femorotibial angle (FTA) and joint line convergence angle (JLCA) were measured. The VTA was measured using IMU sensors on the thigh and tibia, and the differences between lateral and medial VTA were defined as femoral and tibial ΔVTA, respectively. Spearman’s correlation coefficient and linear regression were used for analysis. Results: The standing TA was significantly correlated with the FTA (ρ = 0.47, p = 0.04) and JLCA (ρ = 0.80, p < 0.01). The ΔTA was significantly associated with femoral ΔVTA (β = 0.70, p < 0.01) and tibial ΔVTA (β = 0.67, p < 0.01). Conclusions: Surface-measured TA reflects radiographic alignment. The ΔTA also captures dynamic instability not explained by static measures, suggesting its potential utility as an assessment indicator, although further validation is warranted. Full article
Show Figures

Graphical abstract

10 pages, 1364 KB  
Article
Automated Detection of Lumbosacral Transitional Vertebrae on Plain Lumbar Radiographs Using a Deep Learning Model
by Donghyuk Kwak, Du Hyun Ro and Dong-Ho Kang
J. Clin. Med. 2025, 14(21), 7671; https://doi.org/10.3390/jcm14217671 - 29 Oct 2025
Cited by 1 | Viewed by 1407
Abstract
Background/Objectives: Lumbosacral transitional vertebra (LSTV) is a common anatomical variant, but its identification on plain radiographs is often inconsistent. This inconsistency can lead to clinical complications such as chronic low back pain, misinterpretation of spinal parameters, and an increased risk of wrong-level [...] Read more.
Background/Objectives: Lumbosacral transitional vertebra (LSTV) is a common anatomical variant, but its identification on plain radiographs is often inconsistent. This inconsistency can lead to clinical complications such as chronic low back pain, misinterpretation of spinal parameters, and an increased risk of wrong-level surgery. This study aimed to develop and validate a deep learning-based artificial intelligence (AI) model for the automated detection of LSTV on plain lumbar radiographs. Methods: This retrospective observational study included a total of 3116 standing lumbar lateral radiographs. The presence or absence of lumbosacral transitional vertebra (LSTV) was definitively established using whole-spine imaging, CT, or MRI. Multiple deep learning architectures, including DINOv2, CLIP (ViT-B/32), and ResNet-50, were initially evaluated for binary classification of LSTV. Among these, the ResNet-50 model with partial fine-tuning achieved the best test performance and was subsequently selected for fivefold cross-validation using the training set. Model performance was assessed using accuracy, sensitivity, specificity, and the area under the receiver operating characteristic curve (AUROC), and interpretability was evaluated using gradient-weighted class activation mapping (Grad-CAM). Results: On the independent test set of 313 radiographs, the final model demonstrated robust diagnostic performance. It achieved an accuracy of 76.4%, a sensitivity of 85.1%, a specificity of 61.9%, and an AUC of 0.84. The model correctly identified 166 out of 195 LSTV cases and 73 out of 118 normal cases. Conclusions: This AI-based system offers a highly accurate and reliable method for the automated detection of LSTV on plain radiographs. It shows strong potential as a clinical decision-support tool to reduce diagnostic errors, improve pre-operative planning, and enhance patient safety. Full article
Show Figures

Figure 1

11 pages, 1501 KB  
Article
Expandable Interbody Cages in 1–3 Level Circumferential Lumbar Arthrodesis with 2-Year Follow up: A Retrospective Study
by Fava Marco, Vommaro Francesco, Toscano Angelo, Ciani Giovanni, Parciante Antonio, Mendola Elena, Nervuti Giuliana, Maccaferri Bruna and Gasbarrini Alessandro
Bioengineering 2025, 12(11), 1169; https://doi.org/10.3390/bioengineering12111169 - 28 Oct 2025
Viewed by 1053
Abstract
Introduction: Currently, static interbody cages are the gold standard for achieving solid arthrodesis in the spine, enhancing segmental stability, obtaining neuroforaminal decompression, and improving as well as maintaining segmental lordosis. It is well known that restoring sagittal balance and segmental lordosis is [...] Read more.
Introduction: Currently, static interbody cages are the gold standard for achieving solid arthrodesis in the spine, enhancing segmental stability, obtaining neuroforaminal decompression, and improving as well as maintaining segmental lordosis. It is well known that restoring sagittal balance and segmental lordosis is crucial for long-term outcomes in lumbar spine fusion. For some cases, expandable interbody cages are emerging as an alternative to static cages. This study aims to evaluate the radiographic outcomes and complications of standard open transforaminal lumbar interbody fusion (TLIF). Methods: A standard open TLIF procedure using expandable cages was performed at 1 to 3 levels in 71 patients (129 levels in total), with a follow-up of two years. All patients underwent radiological assessments preoperatively, immediately postoperatively, and at one and two years postoperatively. Radiological evaluation was conducted using standing lateral X-rays. Results: Segmental lordosis (SL) increased significantly from the preoperative value (9.0° ± 3.6°) to 24 months postoperatively (15.4° ± 3.0°), with improvements maintained throughout the 24-month follow-up period (p < 0.001). Similarly, anterior disc height (ADH), posterior disc height (PDH), and foraminal height (FH) each increased significantly from preoperative to immediate postoperative measurements, and these gains were maintained over the two-year follow-up (p < 0.001 each). Lumbar lordosis increased significantly from the preoperative value (41.9° ± 10.5°) to the immediate postoperative period (45.7° ± 10.8°); however, this improvement decreased slightly at the one- and two-year follow-ups. No revisions were required for cage-related complications. One patient experienced a surgical site infection, and two patients had mechanical complications (screw loosening and proximal junctional kyphosis). Conclusions: Expandable interbody cages enable excellent restoration and maintenance of disc height and segmental lordosis in a standard open TLIF procedures at two-year. Achieving these outcomes depends on several factors, including proper preparation of the vertebral endplates, accurate cage placement and expansion, posterior facet osteotomy, and the application of posterior compression prior to final fixation. These steps are essential to fully maximize the potential of expandable cage technology. Full article
Show Figures

Figure 1

14 pages, 2856 KB  
Article
Body Mass Index and Spinopelvic Alignment as Predictors of Incident Knee Osteoarthritis: An 8-Year Longitudinal Study from the TOEI Cohort of Older Japanese Women
by Yuki Murakami, Mitsuru Hanada, Kazuki Nomoto, Kensuke Hotta, Yuki Yamagishi and Yukihiro Matsuyama
J. Clin. Med. 2025, 14(20), 7343; https://doi.org/10.3390/jcm14207343 - 17 Oct 2025
Viewed by 885
Abstract
Background/Objectives: Knee osteoarthritis (KOA) is multifactorial, and longitudinal evidence isolating early predictors remains limited. We investigated predictors of incident KOA in community-dwelling older adult Japanese women. Methods: We analyzed 191 knees from 105 women aged ≥50 years (baseline Kellgren–Lawrence (KL) grade [...] Read more.
Background/Objectives: Knee osteoarthritis (KOA) is multifactorial, and longitudinal evidence isolating early predictors remains limited. We investigated predictors of incident KOA in community-dwelling older adult Japanese women. Methods: We analyzed 191 knees from 105 women aged ≥50 years (baseline Kellgren–Lawrence (KL) grade 0–1) and followed them for 8 years. Incident KOA was defined as KL ≥ 2 at the 8-year follow-up. Baseline measures included body mass index (BMI), physical function (one-leg stance, functional reach), Geriatric Locomotive Function Scale (GLFS-25), EuroQol 5-Dimension (EQ-5D) questionnaire, standing lateral whole-spine radiographs (sagittal spinopelvic parameters), and standing full-length anteroposterior (AP) lower-limb radiographs (coronal alignment parameters). Incident KOA was defined as KL ≥ 2 at follow-up. Group comparisons, multivariable logistic regression, and receiver operating characteristic analyses were conducted. Results: Incident KOA occurred in 58/191 knees (mean participant age 69.3 ± 6.1 years). Compared with non-incident knees, incident knees had higher BMI (23.8 vs. 21.1 kg/m2), higher GLFS-25, greater pelvic tilt and pelvic incidence minus lumbar lordosis (PI–LL) mismatch (11.5° vs. 5.3°), and lower EQ-5D, medial proximal tibial angle, and joint line obliquity. BMI was the strongest single predictor (area under the curve [AUC] 0.753). PI–LL mismatch showed limited standalone discrimination (AUC 0.596) but improved discrimination when combined with BMI (AUC 0.803). Conclusions: BMI was the primary predictor of incident KOA in this cohort. PI–LL mismatch, while not strongly discriminative alone, acted as a complementary marker consistent with sagittal-alignment-related mechanical stress. Results suggest that early screening and prevention should prioritize weight management, using spinopelvic parameters to refine risk stratification. Full article
(This article belongs to the Section Orthopedics)
Show Figures

Figure 1

11 pages, 2090 KB  
Article
Comparison of Radiography with Computed Tomography and Magnetic Resonance Imaging in the Measurement of Cervical Lordosis
by Ismail Ertan Sevin, Selin Bozdag, Efecan Erisken and Hasan Kamil Sucu
Medicina 2025, 61(9), 1654; https://doi.org/10.3390/medicina61091654 - 11 Sep 2025
Cited by 1 | Viewed by 2422
Abstract
Background and Objectives: The assessment of cervical lordosis is essential for surgical planning and outcome prediction in patients with cervical spine pathology. This study aims to evaluate the accuracy of cervical lordosis measurements obtained on supine CT and MRI relative to standing [...] Read more.
Background and Objectives: The assessment of cervical lordosis is essential for surgical planning and outcome prediction in patients with cervical spine pathology. This study aims to evaluate the accuracy of cervical lordosis measurements obtained on supine CT and MRI relative to standing lateral radiographs. Materials and Methods: In this retrospective review, 108 patients who underwent standing lateral radiographs, supine CT, and MRI within a 30-day period were identified. C2–C7 Cobb angles were measured on each modality. Using upright radiographs as the reference standard, the predictive capability of both supine CT and supine MRI in classifying kyphotic versus non-kyphotic alignment was calculated. Results: Standing radiographs demonstrated significantly greater lordosis than supine imaging, with mean paired differences of 6.2° versus CT and 5.0° versus MRI (both p < 0.001); however, strong correlations were observed (with CT: r = 0.75; with MRI: r = 0.72; both p < 0.001). Further, CT-based measurements predicted X-ray Cobb angles with an R2 value of 0.57 (estimated X-ray Cobb angle = 8.24 + 0.74 × (CT Cobb angle), β = 0.74, p < 0.001). MRI-based measurements yielded an R2 of 0.51 (estimated X-ray Cobb angle = 7.59 + 0.71 × (MRI Cobb angle), β = 0.71, p < 0.001). At threshold ≥ 0°, CT achieved a 100% NPV for excluding kyphosis on upright radiographs. MRI achieved an NPV of 100% when the Cobb angle was >1.20°. Conclusions: Supine CT and MRI systematically underestimate cervical lordosis but demonstrate strong predictive correlation with standing radiographs and reliably exclude true kyphotic alignment, with each achieving near-perfect NPV at defined thresholds. In cases where standing radiographs are unavailable or nondiagnostic, supine imaging modalities such as CT and/or MRI, where the cervical region appears nonkyphotic, can safely rule out cervical kyphosis and inform surgical planning; however, in cases where the cervical region appears kyphotic on CT and/or MRI, standing radiographs remain essential for accurate assessment. Full article
(This article belongs to the Section Neurology)
Show Figures

Figure 1

13 pages, 894 KB  
Article
Determinants of Surgical Response to Lateral Tibial Hemiepiphysiodesis in Idiopathic and Non-Idiopathic Genu Varum: Real-World Evidence from a Tertiary Pediatric Cohort
by Giovanni Trisolino, Tosca Cerasoli, Giulio Maria Marcheggiani Muccioli, Marina Magnani, Irene Bosi, Susanna Nanni, Gianmarco Di Paola and Gino Rocca
J. Clin. Med. 2025, 14(16), 5706; https://doi.org/10.3390/jcm14165706 - 12 Aug 2025
Viewed by 1639
Abstract
Background: Lateral tibial hemiepiphysiodesis with tension band plates is an established method for correcting genu varum in skeletally immature patients. However, outcomes may vary depending on underlying pathology and patient characteristics. Methods: This retrospective cohort study evaluated 31 patients (53 knees) [...] Read more.
Background: Lateral tibial hemiepiphysiodesis with tension band plates is an established method for correcting genu varum in skeletally immature patients. However, outcomes may vary depending on underlying pathology and patient characteristics. Methods: This retrospective cohort study evaluated 31 patients (53 knees) treated between 2011 and 2024 at a tertiary pediatric orthopedic center. Patients were categorized as idiopathic or non-idioathic genu varum based on diagnosis. Inclusion criteria required open physes, absence of previous or concomitant knee surgeries for alignment correction, and availability of standardized long-standing radiographs. Radiographic parameters, including mechanical axis deviation (MAD), hip–knee–ankle angle (HKA), and medial proximal tibial angle (MPTA), were assessed pre-operatively and at implant removal. Outcomes were classified as complete correction, partial correction, absent correction, overcorrection, or progression of deformity. Results: Overall, 64.2% of knees achieved complete correction. Success was significantly higher in idiopathic cases (82.1%) than in non-idiopathic deformities (44%). Success was also more frequent in males (p = 0.040). In multivariable analysis, non-idiopathic patients (β = 351.9; p = 0.002), HKA improvement (β = 1.4; p = 0.010) and change in BMI z-score (β = 202.4; p = 0.009) independently predicted surgical success. No major complications (Clavien–Dindo–Sink grade > 2) were observed. Conclusions: Lateral tibial hemiepiphysiodesis is effective for idiopathic genu varum, offering minimally invasive correction with low complication rates. However, outcomes in non-idiopathic deformities are less predictable, emphasizing the need for individualized treatment planning and counseling. Early intervention, careful implant positioning, and rigorous follow-up are essential to optimize results and prevent unintended overcorrection. Full article
(This article belongs to the Special Issue Recent Research Progress in Pediatric Orthopedic Surgery)
Show Figures

Figure 1

11 pages, 2375 KB  
Article
Stand-Alone Lateral Lumbar Interbody Fusion at L3-L4 with 3D-Printed Porous Titanium Cages: A Safe and Effective Alternative in the Treatment of Degenerative Disc Disease (DDD)
by Luca Ricciardi, Andrea Perna, Sokol Trungu, Massimo Miscusi, Alba Scerrati, Annamaria Narciso, Salvatore Cracchiolo, Sara Favarato and Antonino Raco
J. Clin. Med. 2025, 14(12), 4233; https://doi.org/10.3390/jcm14124233 - 14 Jun 2025
Viewed by 1172
Abstract
Background/Objectives: Stand-alone lateral lumbar interbody fusion (LLIF) remains a debated approach in spinal surgery, with limited published evidence supporting its efficacy without supplemental fixation. This prospective study presents the institutional case series on single-level L3-L4 stand-alone LLIF, using next-generation 3D-printed titanium cages, as [...] Read more.
Background/Objectives: Stand-alone lateral lumbar interbody fusion (LLIF) remains a debated approach in spinal surgery, with limited published evidence supporting its efficacy without supplemental fixation. This prospective study presents the institutional case series on single-level L3-L4 stand-alone LLIF, using next-generation 3D-printed titanium cages, as treatment for degenerative disc disease (DDD). Methods: A cohort of 49 patients with symptomatic DDD, unresponsive to conservative therapy, underwent stand-alone LLIF at L3-L4 (neither posterior pedicle screws nor lateral plating). Clinical outcomes (VAS and ODI) and radiological parameters (disc height, segmental/lumbar lordosis) were collected preoperatively and at 1, 6, and 12 months. Repeated-measures ANOVA with Bonferroni correction was adopted for statistical analysis. Results: Significant improvements were observed in pain and disability scores at all time points, with the mean VAS score decreasing from 6.53 to 0.29, and ODI from 27.6% to 3.84% at one year (p < 0.001). Radiographic analysis confirmed durable increases in disc height and segmental lordosis. Solid fusion was achieved in 97.9% of cases. No patient required posterior revision; transient neurological symptoms were mild and self-limiting. Conclusions: This study demonstrates that stand-alone LLIF at L3-L4 is safe and effective in achieving stable fusion and clinical–radiological improvement. These results challenge the necessity of supplemental fixation and support the broader adoption of a less invasive fusion paradigm. Full article
(This article belongs to the Special Issue Clinical Advances in Spine Disorders)
Show Figures

Figure 1

15 pages, 3264 KB  
Article
Reliability and Radiographic Correlation of the Foot Posture Index-6: A Multi-Rater Analysis in Symptomatic and Asymptomatic Individuals
by Min Gyu Kyung, Yun Jae Cho, Jae Hee Lee, Min Seok Shin, Jay Hoon Park and Dong Yeon Lee
Diagnostics 2025, 15(10), 1214; https://doi.org/10.3390/diagnostics15101214 - 12 May 2025
Cited by 2 | Viewed by 5808
Abstract
Background/Objectives: The foot posture index (FPI-6) is a practical clinical tool for evaluating standing foot posture using six specific criteria. Although widely used, its reliability and correlation with radiographic parameters remain uncertain. This study aimed to assess the inter-rater reliability of the [...] Read more.
Background/Objectives: The foot posture index (FPI-6) is a practical clinical tool for evaluating standing foot posture using six specific criteria. Although widely used, its reliability and correlation with radiographic parameters remain uncertain. This study aimed to assess the inter-rater reliability of the FPI-6, in both asymptomatic individuals and patients with foot and ankle symptoms, and to examine its correlation with radiographic measurements. Methods: We included 40 asymptomatic male volunteers (group A) and 60 symptomatic patients (group B). Four raters independently assessed the FPI-6 scores, and inter-rater reliability was evaluated using the intraclass correlation coefficient. Radiographic parameters included the talocalcaneal angle (TCA) on anteroposterior (AP) and lateral views, talonavicular coverage angle (TNCA), AP talo-first metatarsal angle (TMA), hindfoot alignment angle (HAA), calcaneal pitch angle (CPA), and Meary’s angle (MA). Correlations between the FPI-6 and radiographic measurements were analyzed using Pearson’s correlation (r). Results: The FPI-6 showed good to excellent inter-rater reliability in both groups, with higher consistency in group B and among experienced raters. The total FPI-6 score significantly correlated with TNCA (r = 0.665), AP TMA (r = 0.453), lateral TCA (r = 0.369), MA (r = 0.570), and HAA (r = −0.773) (all p < 0.001). Group B demonstrated overall stronger correlations between the FPI-6 and radiographic measurements compared to group A (TNCA: 0.664 vs. 0.258; AP TMA: 0.542 vs. 0.139; lateral TCA: 0.492 vs. −0.101; MA: 0.544 vs. 0.172; and HAA: −0.712 vs. −0.374). Conclusions: With careful application, the FPI-6 is a reliable and valid tool for clinical assessment of foot posture, especially in settings without immediate access to radiographs. Full article
(This article belongs to the Special Issue Advances in Foot and Ankle Surgery: Diagnosis and Management)
Show Figures

Figure 1

12 pages, 952 KB  
Article
Evaluating Variations in Spinopelvic Parameters from Sitting to Standing: A Comparative Analysis of 1447 Older Adults Across Age, BMI, and Gender Subgroups
by Atahan Durbas, Tejas Subramanian, Chad Simon, Myles R. J. Allen, Justin Samuel, Luis Felipe Colón, Michael R. Mazzucco, Cale Pagan, Theofilos Karasavvidis, Jonathan Vigdorchik, Matthew E. Cunningham, Han Jo Kim and Francis C. Lovecchio
J. Clin. Med. 2025, 14(9), 2952; https://doi.org/10.3390/jcm14092952 - 24 Apr 2025
Viewed by 2743
Abstract
Background/Objectives: Sagittal spinal alignment goals for adult spinal deformity (ASD) surgery are predominantly derived from standing radiographs, despite the biomechanical relevance of sitting posture. Existing studies on sitting alignment involve young, healthy cohorts, which poorly represent ASD patients. This study assessed posture-dependent [...] Read more.
Background/Objectives: Sagittal spinal alignment goals for adult spinal deformity (ASD) surgery are predominantly derived from standing radiographs, despite the biomechanical relevance of sitting posture. Existing studies on sitting alignment involve young, healthy cohorts, which poorly represent ASD patients. This study assessed posture-dependent changes in spinopelvic parameters, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordosis (LL), and examined how age, BMI, and gender influence these changes. Methods: In this retrospective cohort study, sitting and standing lateral radiographs of 1447 patients were evaluated. Spinopelvic parameters were measured, and changes (ΔPI, ΔPT, ΔSS, and ΔLL) were calculated. Multiple regression analysis was used to determine associations between these changes and age, BMI, and gender. Results: All parameters differed significantly between positions (p < 0.001); PT and PI increased in sitting (ΔPT = −19.20°; ΔPI = −4.52°), while SS and LL increased in standing (ΔSS = 14.67°; ΔLL = 18.44°). Older age correlated with increased ΔPT (p < 0.001) and ΔPI (p = 0.049) but reduced ΔLL and ΔSS (p < 0.001). Higher BMI was associated with decreased ΔPI, ΔPT, and ΔLL (p < 0.001, 0.003, and 0.025). Females showed greater ΔPT (p = 0.013) but smaller ΔPI, ΔSS, and ΔLL (p = 0.043, <0.001, and 0.001). Conclusions: Spinopelvic parameters vary significantly between sitting and standing positions, affected by age, BMI, and gender. The observed PI change suggests SIJ involvement, highlighting the need for posture-specific and demographic-adjusted alignment goals in ASD surgery to optimize outcomes. Full article
(This article belongs to the Section Orthopedics)
Show Figures

Figure 1

9 pages, 1188 KB  
Case Report
Intranasal Dental Repulsion of a Displaced Cheek Tooth in an Arabian Filly
by Alessandro Spadari, Giuditta Saragoni, Federica Meistro, Maria Virginia Ralletti, Francesca Marzari and Riccardo Rinnovati
Animals 2025, 15(6), 772; https://doi.org/10.3390/ani15060772 - 8 Mar 2025
Viewed by 1399
Abstract
This case report documents an unusual cheek tooth (CT) displacement in a 3-year-old Arabian filly. The horse was referred to the clinic for loss of appetite and right-sided facial deformity. At admission, an oral inspection was performed, followed by a dental radiographic examination. [...] Read more.
This case report documents an unusual cheek tooth (CT) displacement in a 3-year-old Arabian filly. The horse was referred to the clinic for loss of appetite and right-sided facial deformity. At admission, an oral inspection was performed, followed by a dental radiographic examination. The radiographs showed a very oblique vertical angulation (135°) of the CT 106 compared to the other premolars (107 and 108 CTs) (40°). In consideration of the clinical and radiographic findings, surgical extraction of the 106 CT was indicated. Due to the unique positioning of the displaced tooth, traditional extraction methods such as standing oral extraction or minimally invasive buccotomy were deemed impractical. An innovative intranasal dental repulsion technique was selected to minimize invasiveness while ensuring the possibility of performing a complete oral extraction. The procedure was performed under general anesthesia without requiring skin incisions or a lateral osteotomy of the maxilla. The surgery was successful, with no intra-operative or post-operative complications. This original approach offers a viable alternative for similar cases, reducing the morbidity associated with conventional repulsion techniques. Full article
(This article belongs to the Section Equids)
Show Figures

Figure 1

Back to TopTop