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Keywords = supragastric belching

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14 pages, 2437 KB  
Review
Belching in Gastroesophageal Reflux Disease: Literature Review
by Akinari Sawada, Yasuhiro Fujiwara and Daniel Sifrim
J. Clin. Med. 2020, 9(10), 3360; https://doi.org/10.3390/jcm9103360 - 20 Oct 2020
Cited by 15 | Viewed by 14276
Abstract
Belching is a common phenomenon. However, it becomes bothersome if excessive. Impedance–pH monitoring can classify the belching into two types: gastric belching and supragastric belching (SGB). The former is a physiological mechanism to vent swallowed air from the stomach, whereas the latter is [...] Read more.
Belching is a common phenomenon. However, it becomes bothersome if excessive. Impedance–pH monitoring can classify the belching into two types: gastric belching and supragastric belching (SGB). The former is a physiological mechanism to vent swallowed air from the stomach, whereas the latter is a behavioral disorder. Gastroesophageal reflux disease (GERD) is the most relevant condition in both types of belching. Recent findings have raised awareness that excessive SGB possibly sheds light on the pathogenesis of a part of proton pump inhibitor (PPI) refractoriness in GERD. SGB could cause typical reflux symptoms such as heartburn, regurgitation or chest pain in two ways: SGB-induced gastroesophageal reflux or SGB-induced esophageal distension. In PPI-refractory GERD, it is important to detect hidden SGB as a cause of reflux symptoms since SGB requires psychological treatment instead of high dose PPIs or pain modulators. In the case of PPI-refractory GERD with excessive SGB, recent studies imply that the combination of a psychological approach and conventional treatment can improve treatment outcome. Full article
(This article belongs to the Special Issue New Advances in Gastroesophageal Reflux Disease)
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