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Background/Objectives: Recent evidence challenges the classical chemiosmotic theory, suggesting that proton movement along membrane surfaces—not bulk-phase gradients—drives bioenergetic processes. Proton accumulation on membranes like the myelin sheath and endoplasmic reticulum (ER) may represent a universal mechanism for cellular energy storage. This study investigates whether phospholipids from these membranes, combined with anionic bee venom proteins, enhance proton absorption, potentially elucidating a novel bioenergetic pathway. Methods: Five phospholipids (phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, sphingomyelin, phosphatidylcholine) from rat liver were isolated to model myelin/ER membranes. Anionic proteins (pI 5.65–5.80) were purified from bee venom via cation exchange chromatography. Liposomes (with/without proteins) were prepared, and proton absorption was quantified by pH changes in suspensions versus pure water. Statistical significance was assessed via ANOVA and t-tests. Results: All phospholipid liposomes examined in this study absorbed protons under the tested conditions, with phosphatidylethanolamine showing the highest capacity (pH increase: 7.00 → 7.18). Liposomes enriched with anionic proteins exhibited significantly greater proton absorption (e.g., phosphatidylserine + proteins: pH 8.15 vs. 7.15 alone; p < 2.43 × 10⁻⁶). Sphingomyelin-protein liposomes absorbed the most protons, suggesting that protein–phospholipid interactions modulate surface proton affinity. Conclusions: Anionic bee venom proteins amplify proton absorption by phospholipid membranes, supporting the hypothesis that lipid–protein complexes act as “proton capacitors”. This mechanism may underpin extramitochondrial energy storage in myelin and ER. Pharmacologically, targeting these interactions could mitigate bioenergetic deficits in aging or disease. Further research should define the structural basis of proton capture by membrane-anchored proteins. Full article

To investigate the impact of Integrated Mining-Backfill-Roof Contact (IMBR) synergy on strata subsidence in metallic deposits and analyze strata/surface movement patterns, this study enables safe, efficient, environmentally conscious, and sustainable mining development. Focusing on a representative metal mine, we integrated laboratory testing, theoretical analysis, and numerical modeling to determine experimental parameters. Utilizing MIDAS GTS NX, numerical models incorporated four orebody dip angles (30°, 50°, 70°, 90°), five stress release coefficients (20–100%), and contacted/uncontacted conditions to assess IMBR’s control efficacy on surrounding rock stability and surface subsidence. By examining strata/surface movement under variable dip angles and stress release coefficients, displacement control mechanisms were quantified, revealing strata movement evolution principles. Key findings indicate: (1) For all dip angles, the increase rate of displacement progressively intensifies as the excavation stress release coefficient decreases. Notably, at a 30° dipping angle, the most pronounced reduction occurs under declining stress release coefficients, with overall displacement reduction rates reaching 17% for ground surface and 18% for surrounding rock, respectively. (2) Surface displacement impacts intensify as dip angles flatten. (3) Shallower dips induce more pronounced stress disturbance, expanding overburden movement domains and exacerbating surface impacts. Finite element numerical modeling enables accurate and effective analysis of strata and ground movement patterns under varying orebody dipping angles and mining-backfill stress release coefficients. Findings demonstrate that IMBR technology, compared to conventional roof-contacted backfilling methods, achieves timely roof support through immediate backfill-roof contact, significantly reduces overburden fracture propagation depth, and offers valuable insights for controlling surface subsidence in complex mining conditions—particularly for mining under surface structures. Full article

This paper presents a new approach for providing contextual information in real-world environments. Our approach is consciously designed to be low-threshold; by using mirrors as augmented reality surfaces, no devices such as AR glasses or smartphones have to be worn or held by the user. It enables technical and non-technical objects in the environment to be visually highlighted and thus subtly draw the attention of people passing by. The presented technology enables the provision of information that can be viewed in more detail by the user if required by slowing down their movement. Users can decide whether this is relevant to them or not. A prototype system was implemented and evaluated through a user study. The results show a high level of acceptance and intuitive usability of the system, with participants being able to reliably perceive and process the information displayed. The technology thus offers promising potential for the unobtrusive and context-sensitive provision of information in various application areas. The paper discusses limitations of the system and outlines future research directions to further optimize the technology and extend its applicability. Full article

The automotive industry increasingly relies on 3D modeling technologies to design and manufacture vehicle components with high precision. One critical challenge is optimizing the placement of latches that secure the dashboard side paneling, as these placements vary between models and must maintain minimal tolerance for movement to ensure durability. While generative artificial intelligence (AI) has advanced rapidly in generating text, images, and video, its application to creating accurate 3D CAD models remains limited. This paper proposes a novel framework that integrates a PointNet deep learning model with Python-based CAD automation to predict optimal clip placements and surface thickness for dashboard side panels. Unlike prior studies that focus on general-purpose CAD generation, this work specifically targets automotive interior components and demonstrates a practical method for automating part design. The approach involves generating placement data—potentially via generative AI—and importing it into the CAD environment to produce fully parameterized 3D models. Experimental results show that the prototype achieved a 75% success rate across six of eight test surfaces, indicating strong potential despite the limited sample size. This research highlights a clear pathway for applying generative AI to part design automation in the automotive sector and offers a foundation for scaling to broader design applications. Full article

Anthropologists increasingly engage with healthcare systems, using ethnographic research as a critical tool for understanding and improving healthcare practices. The resulting interactions and collaborations between ethnographers, healthcare practitioners, and administrators often give rise to ‘frictions’—moments of tension, frustrations, misalignments, and misunderstandings. In physics, friction is the force that one object’s surface exerts over another’s to slow its motion, push back against its inherent energy and movement, and is a constant at all touchpoints between the objects, from both sides. While friction often evokes negative connotations, in this article, we look beyond frictions as obstacles, and instead explore them as productive forces that can drive transformation in the healthcare improvement field. Drawing both on the authors’ own experiences and on the work of other anthropologists, we reflect on how friction helps shed light on the dynamics of interdisciplinary work and improve collaboration. We unpack how conceptual and ethical frictions in applied ethnographic work reveal deeper structural and relational insights that would otherwise remain obscured. This article contributes to anthropological discussions on interdisciplinary collaboration and applied practice, and it offers concrete strategies for handling different kinds of friction in health-related ethnographic research. Full article

Fatigue failure of overhead line conductors made of AlMgSi alloys is much more complex than fatigue failure of a single wire. The main difference lies in the fretting phenomenon, which is a significant mechanism initiating fatigue damage. It is generated because of micro-movements between individual wires or outer wires and overhead line fittings. Such movements are mainly caused by aeolian vibrations, which lead to degradation of wire surface, initiation of microcracks, and premature failure of multiple wires. Research based on laboratory experiments and modeling studies simulating real operating conditions made it possible not only to identify the mechanisms leading to failure but also to assess the impact of working conditions on their evolution. According to the obtained results, properly selected heat treatment parameters influence both the mass decrease of the wires and number of cycles to failure due to fretting fatigue. Further development of materials, protective coatings, and methods of durability prediction will reduce the impact of fretting on fatigue failure and thus increase the reliability of power lines. Full article

Soft robot motion performance has long been a core focus in scientific research. This study investigates the motion capabilities of soft robots constructed using poly(N-isopropylacrylamide) (PNIPAM) hydrogels, with key innovations in material design and functional enhancement. By optimizing the hydrogel formulation and incorporating molybdenum disulfide (MoS₂) to endow it with photothermal response properties, the material achieves muscle-like controllable contraction and expansion deformation—a critical breakthrough in mimicking biological motion mechanics. Building on this material advancement, the research team developed a series of soft robotic prototypes to systematically explore the hydrogel’s motion characteristics. A flytrap-inspired soft robot demonstrates rapid opening–closing movements, replicating the swift responsiveness of natural carnivorous plants. For terrestrial locomotion, a hexapod crawling robot utilizes the photo-induced stretch-recovery mechanism of both horizontally configured and pre-bent feet to achieve stable directional propulsion. Most notably, a magnetically driven rolling robot integrates magnetic units to realize versatile multimodal movement: it achieves a stable rolling speed of 1.8 cm/s across flat surfaces and can surmount obstacles up to 1.5 times its own body size. This work not only validates the strong potential of PNIPAM hydrogel-based soft robots in executing complex motion tasks but also provides valuable new insights for the development of multimodal soft robotic systems, paving the way for future innovations in adaptive and bio-inspired robotics. Full article

Underground pressurized pipe leakage can induce sand fluidization, leading to ground collapses in urban areas. Additionally, the defluidization process is one of the main causes of sinkholes. In this study, a physical model test was conducted to examine sand bed fluidization and defluidization through a slot, which allowed precise control of the water flow rate in increments of 10 mL/s. The sand layer movement during the experiments was recorded, and the pressure field was accurately measured. The fluidization and defluidization processes were classified into five stages: fluidization static bed, internal fluidization, surface fluidization, internal defluidization, and defluidization static bed. Subsequently, the static bed stage included slow fluidization and fast fluidization, with the former driven by seepage and the latter involving densification and upward movement of sand particles above the orifice. Fluidization initiated at 240 mL/s when the sand particles near the orifice were compressed to approximately minimum porosity 0.37. The head losses comprised orifice head loss, seepage head loss, and vortex head loss, each exhibiting different variation patterns with the water flow rate. Hysteresis was observed in the cavity height curve, attributed to the arching effect. The findings of this study contribute to a more comprehensive understanding of effective strategies for preventing ground collapse. Full article

This study aimed to investigate vertical variations in dissolved organic matter (DOM) properties, humus (HS) composition, humic acid (HA) characteristics, and clay mineral dynamics, with a particular focus on the vertical distribution of HS components and mineral composition across Dark-brown, Meadow, and Paddy soil profiles. Results indicated that: (1) DOM in all three soil types was predominantly endogenous, primarily derived from microbial metabolism with minimal contributions from plant residues. (2) Vertical trends in DOM carbon content (C_DOM) were specific to soil type: in Dark-brown soil, C_DOM slightly increased from the Ap to Bt layer, followed by a sharp increase in the C layer; Meadow soil exhibited a significant decrease in C_DOM in the AB layer but remained relatively stable in other layers; Paddy soil showed a consistent decline in C_DOM with increasing depth. (3) HS and its fractions exhibited vertical variability: Paddy soil showed higher HS content in surface layers; carbon contents of water-soluble substances, HA, and humic-extracted acid (C_WSS, C_HA, and C_HE) decreased with depth in Dark-brown and Paddy soils, whereas they remained relatively stable in deeper layers of Meadow soil. (4) HA characteristics, including C/N ratio, functional groups, and aromaticity, were influenced by both depth and soil type: the Ap2 layer of Paddy soil effectively restricted the downward movement of organic matter; Fe³⁺ complexation played a key role in HA stabilization in Dark-brown soil; Meadow soil exhibited transitional HS properties. (5) Clay mineral assemblages were dominated by 2:1 type minerals (illite, smectite, illite–smectite interstratifications), showing distinct vertical weathering patterns: illite content decreased with depth due to hydrolysis, while proton-driven dissolution promoted kaolinite formation in surface layers, particularly in Dark-brown soil 2:1 minerals enhancing organic–mineral complexation in Meadow soil. The findings of this study provided a scientific basis for optimizing soil carbon pool management and offer insights into organic–mineral interactions that can enhance organic matter sequestration in agricultural soils. Full article

In this study, an innovative passive stability-enhancing barge platform geometry is presented to improve the operational efficiency of floating offshore wind turbines (FOWTs) by mitigating platform motion caused by wave action. Barge-type FOWTs, which primarily rely on surface support, have received less attention in terms of geometric optimization. The proposed design incorporates skirts and a trapezoidal cross-sectional shape for the barge platforms.To achieve effective stability given cost-effect considerations, geometrical optimization was performed while maintaining the same mass as the original design. Positioning the skirt with a height-to-diameter ratio of 0.8 reduces platform movements considerably, decreasing the heave by approximately 20% and the pitch by up to 70% relative to the original design. In addition, the analysis demonstrated that increasing the moonpool area to approximately 400 m² (approximately 10% of the platform’s surface area) led to an additional reduction in the heave and pitch responses. A specific moonpool diameter saturation point value was identified to increase the stability of the floater. Finally, the platform configuration yielded consistently lower peak motions across different wave angles, demonstrating improved stability. Full article

Asymmetric nanomotors are a class of self-propelled nanoparticles that exhibit asymmetries in shape, composition, or surface properties. Their unique asymmetry, combined with nanoscale dimensions, endows them with significant potential in environmental and biomedical fields. For instance, glutathione (GSH) induced chemotactic nanomotors can respond to the overexpressed glutathione gradient in the tumor microenvironment to achieve autonomous chemotactic movement, thereby enhancing deep tumor penetration and drug delivery for efficient induction of ferroptosis in cancer cells. Moreover, self-assembled spearhead-like silica nanomotors reduce fluidic resistance owing to their streamlined architecture, enabling ultra-efficient catalytic degradation of lipid substrates via high loading of lipase. This review focuses on three core areas of asymmetric nanomotors: scalable fabrication (covering synthetic methods such as template-assisted synthesis, physical vapor deposition, and Pickering emulsion self-assembly), propulsion mechanisms (chemical/photo/biocatalytic, ultrasound propelled, and multimodal driving), and functional applications (environmental remediation, targeted biomedicine, and microelectronic repair). Representative nanomotors were reviewed through the framework of structure–activity relationship. By systematically analyzing the intrinsic correlations between structural asymmetry, energy conversion efficiency, and ultimate functional efficacy, this framework provides critical guidance for understanding and designing high-performance asymmetric nanomotors. Despite notable progress, the prevailing challenges primarily reside in the biocompatibility limitations of metallic catalysts, insufficient navigation stability within dynamic physiological environments, and the inherent trade-off between propulsion efficiency and biocompatibility. Future efforts will address these issues through interdisciplinary synthesis strategies. Full article

Blisks are complex thin-walled parts with specific structures that have narrow channels and a large degree of bowed-twisted blades. Five-axis machining technology critically influences blisk surface quality and production efficiency, as the toolpath determines machining accuracy for complex curved blades. A method of optimal cutter location calculation for linear interpolation path based on the constraint of equal theoretical machining error is proposed. Based on the kinematics model of the machine tool, the mapping relationship between the trajectory deviation of the five-axis of machine tool and the tool pose deviation in the workpiece coordinate system is established, and then the maximum overcut/undercut value under the coupling action of the tool tip deviation and the tool orientation deviation is estimated. Based on this, a method to estimate the upper limit of theoretical machining error caused during the movement of the tool along the linear path is proposed. And the algorithm for searching discrete cutter locations on the trajectory of cutting contacts is given to maximize the length of linear path based on the constraint of equal machining error. Experimental results demonstrate that the proposed method effectively reduces redundant cutter locations on linear paths and enhances blisk surface quality by replacing conventional constant chord error control with a more preblisk machining error constraint. Full article

In arid and semi-arid regions, soil salinization has emerged as an escalating environmental challenge. Soil salinity not only alters the soil structure but also influences water movement and distribution. The coupled processes of water movement, heat transfer, and solute transport in the vadose zone interact dynamically, warranting an in-depth investigation into coupled processes of matter and energy. This study developed a numerical model of coupled water-vapor–heat–salt transport in the vadose zone, validated through evaporation experiments and compared with a conventional model excluding osmotic potential. It is found that salt presence reduces evaporation rates while enhancing soil moisture movement. Liquid water movement is primarily governed by matric and osmotic potential gradient, whereas water vapor movement is dominated by temperature gradients. Matric potential influences water vapor movement only at the soil surface, and the impact of salt on water vapor movement diminishes with increasing water content. Notably, matric potential significantly affects water vapor movement only when soil water vapor relative humidity is below unity. The proposed model effectively describes multi-field coupling transport and clarifies the role of osmotic potential in regulating liquid and vapor water dynamics. Full article

A zoo-housed alpaca was found recumbent with profuse frothy salivation and an inability to stand. Supportive treatment, including intravenous fluid therapy via the jugular vein and oral administration of activated charcoal, was initiated. Despite these interventions, the animal’s condition progressively worsened, with clinical signs including vomiting and neurological manifestations such as paddling movements and opisthotonus. The alpaca died approximately 4 h after discovery by first observation of clinical signs. Necropsy revealed a large volume of white, foamy fluid present in the tracheal and bronchial lumens. The lungs were dark red and markedly congested and edematous throughout all lobes. Multiple ecchymotic hemorrhages were observed on the mucosal surface of the pyloric region of the third compartment of the stomach and on the serosal surface of the duodenum. Histopathological examination revealed severe pulmonary congestion and edema, along with marked congestion of the liver, spleen, and kidneys. The gastric contents were green and contained plant material, including ten leaves morphologically identified as Japanese pieris (Pieris japonica). Postmortem inspection of the enclosure revealed the presence of Japanese pieris shrubs with evidence of browsing. Based on these findings, acute poisoning from ingestion of Japanese pieris was diagnosed. Full article

Background: The fabrication of orthodontic aligners directly via three-dimensional (3D) printing presents potential to increase the efficiency of aligner production relative to traditional workflows; however, several aspects of the 3D printing process might affect the dimensional fidelity of the fabricated appliances. The aim of this study is to measure the forces expressed by a 3D printed aligner made with TC-85 DAC resin (Grapy Inc., Seoul, Republic of Korea) when an expansion movement of the entire upper dental arch is programmed, comparing the measured forces with those obtained by a common thermoformed aligner (Smart Track^®, Align Technology, Santa Clara, CA, USA). Materials and methods: A patient in transitional mixed dentition was selected, with the presence of all the first molars and permanent upper and lower incisors, and the canines and premolars have not started the exchange. From this patient, a virtual set up of the upper arch has been planned with an expansion of 0.2 mm and 0.4 mm per side; 3 mm horizontal rectangular attachments were added to the set up on the vestibular surface of the permanent molars, deciduous premolars, and deciduous canines. On this set up, 10 Smart Track aligners and 10 3D printed aligners with TC-85 DAC resin were produced. The fabricated aligners were mounted on the machinery used for the test (ElectroForce^® Test Bench; TA Instruments, New Castle, DE, USA) by means of specific supports that simulate the upper arch of the patient (divided into two sides: right and left). To simulate the intraoral environment, the measurements were carried out in a thermostatic bath at a temperature of 37 °C. Results: The key results of this paper showed differences between Smart Track^® and TC-85 DAC. In particular, the expanding force exerted by the 0.2 mm per side expanded Smart Track^® aligners was on average +0.2162 N with a D.S. of ±0.0051 N during the 8 h; meanwhile, the force exerted by the 0.2 mm per side expanded TC-85 DAC 3D printed aligners was on average −0.0034 N with a D.S. of ±0.0036 N during the 8 h. The force exerted by the 0.4 mm per side expanded Smart Track^® aligners was on average +0.7159 N with a D.S. of ±0.0543 N during the 8 h; meanwhile, the force exerted by the 0.4 mm per side expanded TC-85 DAC 3D printed aligners was on average +0.0141 N with a D.S. of ±0.004 N during the 8 h. Conclusions: Smart Track^® aligners express a quantitatively measurable force in Newtons during the programmed movements to obtain a posterior expansion of the dental arches; on the contrary, aligners made with TC-85 DAC resin, in light of the results obtained from this study, express forces close to 0 during the realization of the movements programmed to obtain a posterior expansion of the dental arches. Full article