10,599 Results Found

An emerging trend in sports nutrition is the consumption of energy drinks and “energy shots”. Energy shots may prove to be a viable pre-competition supplement for runners. Six male runners (mean ± SD age and VO₂max: 22.5 ± 1.8 years and 69.1 ± 5.7...

Metabolic syndrome (MetS) and erratic eating patterns are associated with circadian rhythm disruption which contributes to an increased cardiometabolic risks. Restricting eating period (time-restricted eating, TRE) can restore robust circadian rhythm...

Background: Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low levels of a constant current via scalp electrodes to specifically targeted areas of the brain. The effects of tDCS on whole-body exercise perf...

Supplementation with β-alanine is becoming a common practice in high-performance athletes. The purpose of the present study was to investigate the effects of a one-week high-dose β-alanine loading phase employing a sustained-release powder on preserv...

Introduction: Studies evaluating caffeinated coffee (CAF) can reveal ergogenic effects; however, studies on the effects of caffeinated coffee on running are scarce and controversial. Aim: To investigate the effects of CAF consumption compared to deca...

The current study compared mouth swills containing carbohydrate (CHO), menthol (MEN) or a combination (BOTH) on 40 km cycling time trial (TT) performance in the heat (32 °C, 40% humidity, 1000 W radiant load) and investigates associated physiolog...

Following reports of bleeding upon Ginkgo intake, we assessed whether Ginkgo extract EGb 761^® affects coagulation or platelet function or increases the risk of bleeding. In a double-blind, placebo-controlled trial, prothrombin time, activated par...

The space-division multiplexed (SDM) transmission technique based on uncoupled multi-core fibers (MCF) shows great implementation potential due to its huge transmission capacity and compatibility with existing transceivers. In this paper, we demonstr...

This randomized controlled trial is aimed at assessing the efficacy of combining time-restricted eating (TRE) with behavioral economic (BE) interventions and comparing it to TRE alone and to the usual care for reducing fasting plasma glucose (FPG), h...

Competing patterns are compound patterns that compete to be the first to occur a pattern-specific number of times, known as a stopping rule. In this paper, we study a higher-order Markovian dependent Bernoulli trials model with competing patterns. Th...

The pace of clinical trial data generation and publication is an area of interest within clinical oncology; however, little is known about the dynamics and covariates of time to reporting (TTR) of trial results. To assess these, ClinicalTrials.gov wa...

Cyclists usually define their posture according to performance and comfort requirements. However, when modifying their posture, cyclists experience a trade-off between these requirements. In this research, an optimization methodology is developed to...

New Zealand blackcurrant (NZBC) extract increased 16.1 km cycling time trial performance. The aim of the present study was to examine the effect of NZBC extract on 2 × 4 km time trial performance. Ten male cyclists (age: 30 ± 12 years, body mass: 74...

Supervised personal training is most effective in improving the health effects of exercise in older adults. Yet, low frequency (60 min, 1–3 sessions/week) of trainer contact limits influence on behavior change outside sessions. Strategies to ex...

Intra-individual movement variability has historically been discounted as evidence of poor motor control. However, evidence now suggests that it may play a functional role in skill performance and so this study aimed to establish whether this is the...

Ultra-high-speed integrated communication and sensing (ICS) transmission techniques are highly desired for next-generation highly reliable optical transport networks (OTNs). The inherent multiple-channel advantage of uncoupled multi-core fibers (MCFs...

Purpose: To examine the contributions of time in different terrains and sub-technique distribution to overall time-trial performance, as well as the relationships of laboratory and field-based performance determinants in cross-country skiers. Methods...

Aerodynamics is a key factor in time-trial cycling. Over the years, various aspects have been investigated, including positioning, clothing, bicycle design, and helmet shape. The present study focuses on the development of a methodology for the aerod...

This study investigated the real-time progression of heat strain in mountain hikers during time trials (TT). Participants (n = 12; 7M/5F; age 21.6 ± 2.47) attempted to climb Tempe Butte (~1.1 mi) four times in HOT and MOD trials (wet bulb glob...

Background: In the treatment of Onychocryptosis, chemical matricectomy with 88% phenol solution is one of the most common surgical procedures due to a recurrence rate of less than 5%, but it may produce a delay in healing time. The objective was to c...

Much research has been done in sports nutrition in recent years as the demand for performance-enhancing substances increases. Higher intake of nitrates from the diet can increase the bioavailability of nitric oxide (NO) via the nitrate–nitrite&...

The carbohydrate (CHO) concentration of a mouth rinsing solution might influence the CHO sensing receptors in the mouth, with consequent activation of brain regions involved in reward, motivation and regulation of motor activity. The purpose of the p...

We investigated if a carbohydrate (CHO) mouth rinse may attenuate global fatigue and improve 4-km cycling time trial (TT_4km) performance. After a preliminary session, cyclists (n = 9) performed a TT_4km after a CHO or placebo (PLA) mouth rinse. Mean p...

Background: Sitting time has negative effects on health, increasing the risk of obesity, osteoporosis, diabetes, and cancer. Thus, primary health care education interventions aimed to reduce sitting time and sedentary behavior could have beneficial e...

A meta-analysis demonstrated that programmed fluid intake (PFI) aimed at fully replacing sweat losses during a 1 h high-intensity cycling exercise impairs performance compared with no fluid intake (NFI). It was reported that thirst-driven fluid intak...

There is good evidence that mouth rinsing with carbohydrate (CHO) solutions can enhance endurance performance (≥30 min). The impact of a CHO mouth rinse on sprint performance has been less consistent, suggesting that CHO may confer benefits in condit...

Purpose: To determine the impact of interval training frequency in elite endurance athletes. It was hypothesized that two longer sessions would elicit greater performance improvements and physiological adaptation than four shorter sessions at the sam...

This study aimed to assess the trend in oncology trial commencements registered on ClinicalTrials.gov and to evaluate the contributing factors by comparing the trends in the pre- and post-COVID-19 pandemic era. The ClinicalTrials.gov database was sea...

Time to next treatment (TTNT) is an emerging endpoint in clinical studies of primary cutaneous T-cell lymphomas (CTCL), with utility as a surrogate marker for the “duration of clinical benefit”. TTNT provides a highly clinically meaningfu...

Saccadic eye movements are directed to the objects of interests and enable high-resolution visual images in the exploration of the visual world. There is a trial-to-trial variation in saccade dynamics even in a simple task, possibly attributed to aro...

Background/Objectives: Caffeine is a well-established ergogenic aid for endurance performance. However, the optimal intake strategy, specifically the administration method and dosage, remains uncertain. This systematic review and network meta-analysi...

Accuracy and precision of quantitative imaging (QI) metrics should be assessed in real time in each patient during a clinical trial to support QI-based decision-making. We developed a framework for real-time quantitative assessment of QI metrics and...

l-menthol (menthol) is an organic compound derived from peppermint which imparts a refreshing mint flavor and aroma to oral hygiene products, chewing gum, and topical analgesics. Menthol has been identified as a non-thermal sensory cooling strategy f...

The use of mobile power measuring devices has become widespread within cycling, with a number of manufacturers now offering power measuring pedals. This study aimed to investigate the validity of PowerTap P1 pedals by comparing them with the previous...

This study aimed to investigate the influence of a single dose of either beetroot juice (BR) or sodium nitrate (NIT) on performance in a 10 km handcycling time trial (TT) in able-bodied individuals and paracyclists. In total, 14 able-bodied individua...

The purpose of the study was to investigate the effect of dry-land priming (DLP) versus swimming priming (SP) on the 50 m crawl performance of well-trained adolescent swimmers. Thirteen adolescent swimmers were randomly assigned to perform either a D...

Equilibration with an extender is necessary to allow cryopreservation of bovine sperm. The aim of trial 1 was to assess the effect of 24 h versus 4 h equilibration time with three different extenders on sperm quality and to select the preferred exten...

This manuscript examines the synergistic potential of prospective real-world/time data/evidence (RWTD/E) and randomized controlled trials (RCTs) to enrich healthcare research and operational insights, with a particular focus on its impact within the...

Environmental heat stress poses significant physiological challenge and impairs exercise performance. We investigated the impact of wrist percooling on running performance and physiological and perceptual responses in the heat. In a counterbalanced d...

The analysis of the electrocardiogram (ECG) is critical for the diagnosis of arrhythmias. Recent advances in information and communications technology (ICT) have led to the development of wearable ECG devices and arrhythmia-detection algorithms. This...

Objective: This study was conducted to determine whether installation of sit-stand desks (SSDs) could lead to decreased sitting time during the workday among sedentary office workers. Methods: A randomized cross-over trial was conducted from January...

This study aimed to analyze the placebo effect associated with caffeine ingestion on running performance. Methods: Thirteen recreationally trained males in long-distance running (age: 38.5 ± 11.9 years, 11.0 ± 8.8 years of running exper...

Relative to carbohydrate (CHO) alone, exogenous ketones followed by CHO supplementation during recovery from glycogen-lowering exercise have been shown to increase muscle glycogen resynthesis. However, whether this strategy improves subsequent exerci...

Background/Objectives: This study examined the effects of 2 weeks of betaine versus placebo supplementation (3 g/d) on 60 km cycling performance, gut permeability, and shifts in plasma metabolites. Methods: Participants included 21 male and female no...

Caffeine is a well-established ergogenic aid, although research to date has predominantly focused on anhydrous caffeine, and in men. The primary aim of the present study was to investigate the effect of coffee ingestion on 5 km cycling time trial per...

Endurance athletes participating in sporting events may be required to complete multiple training sessions a day or on successive days with a limited recovery time. Nutritional interventions that enhance the restoration of endogenous fuel stores (e.g...

We study a fifth order time-fractional KdV equation (FKdV) under meaning of the conformal fractional derivative. By trial equation method based on symmetry, we construct the abundant exact traveling wave solutions to the FKdV equation. These solution...

Different stainless steel slags have been successfully employed in previous experiments, for the treatment of industrial acidic wastewaters. Although, before this technology can be implemented on an industrial scale, upscaled pilot experiments need t...

Background: Globally, healthcare has shouldered much of the socioeconomic brunt of the COVID-19 pandemic leading to numerous clinical trials suspended or discontinued. Objective: To estimate the COVID-19 impact on the number of clinical trials worldw...

Beyond their effect on blood pressure, the effect of energy drinks on heart rate in children and teenagers has not been evaluated until now. Thus, this study aimed to investigate the acute cardiovascular effects of energy drinks in healthy children a...