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Keywords = tropine ionic liquids

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12 pages, 3509 KB  
Article
Synthesis of Tropine-Based Functionalized Acidic Ionic Liquids and Catalysis of Esterification
by Hongfei Ni, Yiwei Zhang, Chuhong Zong, Zhengbo Hou, Hang Song, Yong Chen, Xuesong Liu, Tengfei Xu and Yingjie Luo
Int. J. Mol. Sci. 2022, 23(21), 12877; https://doi.org/10.3390/ijms232112877 - 25 Oct 2022
Cited by 7 | Viewed by 2627
Abstract
Some traditional acidic ionic liquids (AILs) have shown great catalytic potential in esterification; meanwhile, the design and application of more new AILs are expected at present.Tropine-based functionalized acidic ionic liquids (FAILs) were synthesized to realize esterification catalysis for the first time; with aspirin [...] Read more.
Some traditional acidic ionic liquids (AILs) have shown great catalytic potential in esterification; meanwhile, the design and application of more new AILs are expected at present.Tropine-based functionalized acidic ionic liquids (FAILs) were synthesized to realize esterification catalysis for the first time; with aspirin synthesis as the template reaction, key influences on the substrate conversion and product yield of the synthesis, such as IL type, ratio of salicylic acid to acetic anhydride, temperature, reaction time and amount of IL, were investigated. The new tropine-based FAILs exhibited excellent performance in catalytic synthesis of aspirin with 88.7% yield and 90.8% selectivity. Multiple recovery and re-usage of N-(3-propanesulfonic acid) tropine is the cation, and p-toluenesulfonic acid is the anion. ([Trps][OTs]) shows satisfactory results. When [Trps][OTs] was used to catalyze different esterification reactions, it also showed good results. The above studies proved that ionic liquid [Trps][OTs] could serve as an ideal green solvent for esterification reaction, which serves as a suitable substitute for current catalysts. Full article
(This article belongs to the Special Issue Advanced Functional Materials from Ionic Liquids)
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18 pages, 6584 KB  
Article
Ultrasonic Extraction of Tropane Alkaloids from Radix physochlainae Using as Extractant an Ionic Liquid with Similar Structure
by Alula Yohannes, Baohui Zhang, Bing Dong and Shun Yao
Molecules 2019, 24(16), 2897; https://doi.org/10.3390/molecules24162897 - 9 Aug 2019
Cited by 20 | Viewed by 3857
Abstract
In this research, tropane alkaloids in Radix physochlainae were extracted by tropine-type ionic liquid (IL) aqueous solutions under ultrasound assistance, and N-propyltropine hexafluorophosphate ([C3Tr][PF6]) was found to be the most ideal IL in this extraction mode after comprehensive screening. [...] Read more.
In this research, tropane alkaloids in Radix physochlainae were extracted by tropine-type ionic liquid (IL) aqueous solutions under ultrasound assistance, and N-propyltropine hexafluorophosphate ([C3Tr][PF6]) was found to be the most ideal IL in this extraction mode after comprehensive screening. When 0.03 mol/L [C3Tr][PF6] aqueous solution was chosen as the extraction solvent, the solid-liquid ratio of raw material powders and ionic liquid aqueous solution was 1:20 (g/mL), ultrasonic power was 90 W and extraction time was 30 min, the extraction efficiency of tropane alkaloids has reached 121.3%. Compared with common heating extraction, it can further shorten the extraction time, improve extraction efficiency and decrease IL consumption. Furthermore, extraction mechanism together with potential toxicity of IL have been explored and discussed. Full article
(This article belongs to the Special Issue Technology for Natural Products Research)
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