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Keywords = tympanocentesis

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10 pages, 289 KiB  
Article
Acute Otitis Media in Children—Challenges of Antibiotic Resistance in the Post-Vaccination Era
by Cristina Gavrilovici, Elena-Lia Spoială, Ingrith-Crenguţa Miron, Iuliana Magdalena Stârcea, Codruţa Olimpiada Iliescu Haliţchi, Irina Nicoleta Zetu, Vasile Valeriu Lupu and Carmen Pânzaru
Microorganisms 2022, 10(8), 1598; https://doi.org/10.3390/microorganisms10081598 - 8 Aug 2022
Cited by 13 | Viewed by 4845
Abstract
Acute otitis media (AOM) is a leading cause of antibiotic prescriptions in children worldwide, even in the era of pneumococcal conjugate vaccines. We aimed to assess the bacterial spectrum of AOM in children and to investigate the antimicrobial resistance profile in culture-positive cases. [...] Read more.
Acute otitis media (AOM) is a leading cause of antibiotic prescriptions in children worldwide, even in the era of pneumococcal conjugate vaccines. We aimed to assess the bacterial spectrum of AOM in children and to investigate the antimicrobial resistance profile in culture-positive cases. We performed a retrospective, tympanocentesis-based analysis of antimicrobial resistance patterns in children with AOM hospitalized in “St Mary” Emergency Hospital for Children Iasi, Romania, between January 2013 and December 2021. A total of 147 samples have been assessed, 97 (65.98%) of which had positive cultures, with Streptococcus pneumoniae and Haemophilus influenzae as the most common microorganisms. A worrying proportion, 82.85% (58/70), of the Streptococcus pneumoniae strains were multidrug-resistant. The World Health Organization included Streptococcus pneumoniae and Haemophilus influenzae on the medium priority group due to penicillin non-susceptibility and ampicillin-resistant strains, respectively. Consequently, strategies to address the threats of antimicrobial resistance are needed to reduce the potential negative effects on hospitalization costs. Full article
(This article belongs to the Section Antimicrobial Agents and Resistance)
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