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Search Results (565)

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Keywords = virtual surgery

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13 pages, 876 KB  
Article
Evaluation of the Precision and Accuracy of Computer-Guided Implant Surgery: A Prospective Clinical Study Comparing .STL Files from the Intraoral Rehabilitation Scanning with the Digital Project
by Francesca Argenta, Antonino Palazzolo, Eugenio Romeo, Saturnino Marco Lupi, Tommaso Risciotti, Massimo Scanferla and Stefano Storelli
Appl. Sci. 2026, 16(3), 1652; https://doi.org/10.3390/app16031652 - 6 Feb 2026
Viewed by 34
Abstract
Objectives: This prospective cohort study aimed to evaluate the accuracy and precision of static computer-guided, flapless implant surgery in partially edentulous patients, comparing the virtually planned and clinically achieved implant positions. Materials and Methods: From 2017 to 2022, 40 patients (20 males and [...] Read more.
Objectives: This prospective cohort study aimed to evaluate the accuracy and precision of static computer-guided, flapless implant surgery in partially edentulous patients, comparing the virtually planned and clinically achieved implant positions. Materials and Methods: From 2017 to 2022, 40 patients (20 males and 20 females) received a total of 129 implants across 59 partial rehabilitations, with 62 implants placed in the maxilla and 67 in the mandible. All interventions were performed by a single experienced operator using dental-supported stereolithographic guides and a flapless protocol. The discrepancy between planned and actual implant positions was measured using reverse engineering software, assessing linear deviations at the implant Platform (coronal) and apex, as well as angular deviations. Subgroup analyses were conducted based on the jaw (maxilla vs. mandible) and the type of surgical guide support (Kennedy classes I–IV). Results: The mean linear deviation was 1.16 ± 0.58 mm at the apex and 0.80 ± 0.41 mm at the implant Platform (coronal). The mean angular deviation was 3.23° ± 1.86°. Slightly higher deviations were observed in the mandible than in the maxilla. Group-wise analysis showed minor variations depending on the type of guide support. Conclusions: Static computer-guided surgery demonstrated measurable linear and angular deviations between planned and achieved implant positions. These discrepancies should be considered during treatment planning, especially in narrow ridges or Class I configurations. Full article
(This article belongs to the Special Issue Recent Development and Emerging Trends in Dental Implants)
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15 pages, 1023 KB  
Article
Effect of Counterclockwise Mandibular Autorotation on Temporomandibular Joint Spaces and Condylar Morphology After Bimaxillary Orthognathic Surgery: A CBCT-Based Study
by Mehmet Emre Yurttutan, Merve Berika Kadıoğlu, Meyra Durmaz, Mehmet Alp Eriş, Mahzun Yıldız and Ömer Faruk Kocamaz
J. Clin. Med. 2026, 15(3), 1296; https://doi.org/10.3390/jcm15031296 - 6 Feb 2026
Viewed by 47
Abstract
Background/Objectives: Mandibular counterclockwise (CCW) autorotation following maxillary repositioning is a common biomechanical consequence of bimaxillary orthognathic surgery. However, its effect on temporomandibular joint (TMJ) morphology remains controversial. This study aimed to evaluate whether condyle-centered CCW mandibular autorotation influences postoperative TMJ spaces and condylar [...] Read more.
Background/Objectives: Mandibular counterclockwise (CCW) autorotation following maxillary repositioning is a common biomechanical consequence of bimaxillary orthognathic surgery. However, its effect on temporomandibular joint (TMJ) morphology remains controversial. This study aimed to evaluate whether condyle-centered CCW mandibular autorotation influences postoperative TMJ spaces and condylar morphology using cone-beam computed tomography (CBCT). Methods: A total of 24 patients who underwent combined Le Fort I osteotomy and bilateral sagittal split ramus osteotomy were included in this retrospective analysis. Patients were divided into two groups based on virtual surgical planning: those with condyle-centered CCW autorotation (4–7°) and those without autorotation. Preoperative and one-year postoperative CBCT images were analyzed. Sagittal and coronal joint spaces, condylar dimensions, and glenoid fossa thickness were measured. Intra- and intergroup comparisons were performed using nonparametric statistical tests (α = 0.05). Results: Both groups demonstrated significant postoperative reductions in condylar height, width, and depth, reflecting adaptive bone remodeling. Joint space changes were limited overall. A significant intergroup difference was observed only in the change in the right superior joint space (p = 0.024), which decreased in the non-autorotation group but was preserved or slightly increased in the autorotation group. No other joint space or fossa parameter showed significant between-group differences. Conclusions: Condyle-centered CCW mandibular autorotation during bimaxillary orthognathic surgery does not induce adverse TMJ morphological changes beyond physiological adaptation. Preservation of the superior joint space suggests that autorotation may contribute to maintaining a more favorable condyle–fossa relationship. Incorporating controlled mandibular autorotation into surgical planning may support TMJ biomechanical balance and postoperative joint stability. Full article
(This article belongs to the Special Issue Current Challenges in Oral and Maxillofacial Surgery)
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11 pages, 1020 KB  
Technical Note
Restoring Mandibular Anatomy After Complex Trauma: Clinical Applications of a Statistical Shape Model
by Stephen A. L. Y. Youssef, Cornelis Klop, Juliana F. Sabelis, Ruud Schreurs, Jitske W. Nolte, Renee Helmers, Alfred G. Becking and Leander Dubois
J. Clin. Med. 2026, 15(3), 1223; https://doi.org/10.3390/jcm15031223 - 4 Feb 2026
Viewed by 135
Abstract
Background/Objectives: Restoration of mandibular anatomy following complex trauma remains challenging when conventional anatomical and occlusal references, such as dental occlusion, contralateral morphology, condylar position, or mandibular continuity are lost. This technical note describes the clinical application of a mandibular statistical shape model as [...] Read more.
Background/Objectives: Restoration of mandibular anatomy following complex trauma remains challenging when conventional anatomical and occlusal references, such as dental occlusion, contralateral morphology, condylar position, or mandibular continuity are lost. This technical note describes the clinical application of a mandibular statistical shape model as an alternative anatomical reference for diagnosis, virtual planning, and postoperative evaluation in patients with severe post-traumatic deformities. Methods: The MAGIC-SSM, an open-source, age-, and sex-specific three-dimensional model derived from a normative population dataset, enables reconstruction of plausible mandibular geometry in the absence of residual landmarks. Three clinical cases were analyzed using MAGIC-SSM-based reference alignment, with distance mapping applied when indicated. Results: The model provided an additional anatomical reference that supported decision-making in secondary correction, hybrid reconstruction with patient-specific implants, and quantitative evaluation of postoperative outcomes. Conclusions: By replacing lost spatial references with population-based geometry, the MAGIC-SSM offered support for restoring mandibular form and symmetry. These preliminary findings illustrate the feasibility of applying the MAGIC-SSM as an anatomical framework in complex trauma when conventional guides are absent. As its clinical application involved clinician-guided alignment and scaling, reproducibility and reliability remain to be established and require further validation. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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21 pages, 1351 KB  
Article
B-Onic Platform for Point-of-Care 3D Printing in Oral and Maxillofacial Surgery: Clinical Implementation and Surgical Impact
by José Luis Cebrián-Carretero, Marta Pampín-Martínez, José Tadeo Borjas Gómez, Celia del Peso Ley, Rubén Rubio Bolivar, Celia Matín Cubillo, Bárbara Martínez de Miguel, Montserrat Bret Zurita, Federico Gutiérrez Larraya, Javier Cobas Gamallo, Carlos Navarro-Cuéllar and Jorge Magaña
Medicina 2026, 62(2), 319; https://doi.org/10.3390/medicina62020319 - 3 Feb 2026
Viewed by 166
Abstract
Background and Objectives: The integration of digital planning and point-of-care (POC) manufacturing has expanded rapidly in oral and maxillofacial surgery (OMFS); however, evidence focusing on regulated, platform-based workflows and their clinical impact remains limited. This study aimed to evaluate the clinical and [...] Read more.
Background and Objectives: The integration of digital planning and point-of-care (POC) manufacturing has expanded rapidly in oral and maxillofacial surgery (OMFS); however, evidence focusing on regulated, platform-based workflows and their clinical impact remains limited. This study aimed to evaluate the clinical and organizational impact of implementing a unified digital ecosystem centered on the B-Onic platform in routine OMFS practice. Materials and Methods: A retrospective observational study was conducted comparing OMFS procedures planned and executed using the B-Onic platform with a historical control cohort managed with conventional workflows. Surgical cases were categorized into four pathology-based subgroups: facial trauma, oncologic resection and reconstruction, orthognathic surgery, and craniofacial or skull base surgery. Outcomes included preoperative planning time, validation time for guides and implants, surgical duration, intraoperative plan modifications, postoperative complications, 30-day rehospitalization rates, length of hospital stay, and estimated intraoperative blood loss. Results: A total of 110 cases managed using the B-Onic platform were compared with 72 historical control cases. Implementation of the platform was associated with significant reductions in preoperative planning time, validation time, and surgical duration. Clinically relevant improvements were observed in postoperative outcomes, including lower complication rates, reduced 30-day rehospitalization, shorter hospital stays, fewer intraoperative plan modifications, and decreased estimated blood loss. The magnitude of benefit was greatest in high-complexity procedures—particularly oncologic resection and reconstruction and craniofacial or skull base surgery—while more modest effects were observed in orthognathic surgery, reflecting optimized baseline outcomes. Conclusions: The adoption of a regulated, platform-based POC digital ecosystem in oral and maxillofacial surgery is associated with meaningful improvements in workflow efficiency, surgical reproducibility, and postoperative outcomes, especially in complex procedures. These findings support the integration of unified digital platforms as a core component of contemporary OMFS practice and provide OMFS-specific evidence of their clinical and organizational value. Full article
(This article belongs to the Special Issue New Trends and Advances in Oral and Maxillofacial Surgery)
9 pages, 399 KB  
Review
Fracture of Rotary Instruments in Third Molar Extraction: Evidence from a Scoping Review
by Luca Gentili, Roberto Fontanella, Marco Messi, Cosimo Galletti, Roberto Lo Giudice and Francesco Puleio
Clin. Pract. 2026, 16(2), 33; https://doi.org/10.3390/clinpract16020033 - 2 Feb 2026
Viewed by 74
Abstract
Background: Rotary instrument fracture during third molar extraction is rare but clinically relevant, presenting diagnostic and therapeutic challenges. Aim: This scoping review summarizes available evidence on bur breakage and displacement during third molar surgery, focusing on causes, clinical manifestations, and management strategies. Materials [...] Read more.
Background: Rotary instrument fracture during third molar extraction is rare but clinically relevant, presenting diagnostic and therapeutic challenges. Aim: This scoping review summarizes available evidence on bur breakage and displacement during third molar surgery, focusing on causes, clinical manifestations, and management strategies. Materials and Methods: A systematic search of PubMed, Virtual Health Library, and Google Scholar was conducted for studies published from January 2008 to March 2025 reporting rotary instrument fracture during third molar extraction. Extracted data were qualitatively analyzed. Results: Eight studies reporting eleven clinical cases were included. All fractures occurred during mandibular third molar extractions. Pain was the most frequent symptom (45%), followed by swelling (27%) and trismus (18%). Management varied from immediate surgical retrieval to conservative observation. Conclusions: Although uncommon, rotary bur fracture during third molar extraction requires preventive attention and accurate reporting. Adherence to manufacturer recommendations, single-use bur policies, and adequate irrigation should be considered. Prospective multicenter and mechanical studies are needed to establish standardized management protocols. Full article
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20 pages, 942 KB  
Review
Artificial Intelligence in Minimally Invasive and Robotic Gastrointestinal Surgery: Major Applications and Recent Advances
by Matteo Pescio, Francesco Marzola, Giovanni Distefano, Pietro Leoncini, Carlo Alberto Ammirati, Federica Barontini, Giulio Dagnino and Alberto Arezzo
J. Pers. Med. 2026, 16(2), 71; https://doi.org/10.3390/jpm16020071 - 31 Jan 2026
Viewed by 322
Abstract
Artificial intelligence (AI) is rapidly reshaping gastrointestinal (GI) surgery by enhancing decision-making, intraoperative performance, and postoperative management. The integration of AI-driven systems is enabling more precise, data-informed, and personalized surgical interventions. This review provides a state-of-the-art overview of AI applications in GI surgery, [...] Read more.
Artificial intelligence (AI) is rapidly reshaping gastrointestinal (GI) surgery by enhancing decision-making, intraoperative performance, and postoperative management. The integration of AI-driven systems is enabling more precise, data-informed, and personalized surgical interventions. This review provides a state-of-the-art overview of AI applications in GI surgery, organized into four key domains: surgical simulation, surgical computer vision, surgical data science, and surgical robot autonomy. A comprehensive narrative review of the literature was conducted, identifying relevant studies of technological developments in this field. In the domain of surgical simulation, AI enables virtual surgical planning and patient-specific digital twins for training and preoperative strategy. Surgical computer vision leverages AI to improve intraoperative scene understanding, anatomical segmentation, and workflow recognition. Surgical data science translates multimodal surgical data into predictive analytics and real-time decision support, enhancing safety and efficiency. Finally, surgical robot autonomy explores the progressive integration of AI for intelligent assistance and autonomous functions to augment human performance in minimally invasive and robotic procedures. Surgical AI has demonstrated significant potential across different domains, fostering precision, reproducibility, and personalization in GI surgery. Nevertheless, challenges remain in data quality, model generalizability, ethical governance, and clinical validation. Continued interdisciplinary collaboration will be crucial to translating AI from promising prototypes to routine, safe, and equitable surgical practice. Full article
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32 pages, 27435 KB  
Review
Artificial Intelligence in Adult Cardiovascular Medicine and Surgery: Real-World Deployments and Outcomes
by Dimitrios E. Magouliotis, Noah Sicouri, Laura Ramlawi, Massimo Baudo, Vasiliki Androutsopoulou and Serge Sicouri
J. Pers. Med. 2026, 16(2), 69; https://doi.org/10.3390/jpm16020069 - 30 Jan 2026
Viewed by 308
Abstract
Artificial intelligence (AI) is rapidly reshaping adult cardiac surgery, enabling more accurate diagnostics, personalized risk assessment, advanced surgical planning, and proactive postoperative care. Preoperatively, deep-learning interpretation of ECGs, automated CT/MRI segmentation, and video-based echocardiography improve early disease detection and refine risk stratification beyond [...] Read more.
Artificial intelligence (AI) is rapidly reshaping adult cardiac surgery, enabling more accurate diagnostics, personalized risk assessment, advanced surgical planning, and proactive postoperative care. Preoperatively, deep-learning interpretation of ECGs, automated CT/MRI segmentation, and video-based echocardiography improve early disease detection and refine risk stratification beyond conventional tools such as EuroSCORE II and the STS calculator. AI-driven 3D reconstruction, virtual simulation, and augmented-reality platforms enhance planning for structural heart and aortic procedures by optimizing device selection and anticipating complications. Intraoperatively, AI augments robotic precision, stabilizes instrument motion, identifies anatomy through computer vision, and predicts hemodynamic instability via real-time waveform analytics. Integration of the Hypotension Prediction Index into perioperative pathways has already demonstrated reductions in ventilation duration and improved hemodynamic control. Postoperatively, machine-learning early-warning systems and physiologic waveform models predict acute kidney injury, low-cardiac-output syndrome, respiratory failure, and sepsis hours before clinical deterioration, while emerging closed-loop control and remote monitoring tools extend individualized management into the recovery phase. Despite these advances, current evidence is limited by retrospective study designs, heterogeneous datasets, variable transparency, and regulatory and workflow barriers. Nonetheless, rapid progress in multimodal foundation models, digital twins, hybrid OR ecosystems, and semi-autonomous robotics signals a transition toward increasingly precise, predictive, and personalized cardiac surgical care. With rigorous validation and thoughtful implementation, AI has the potential to substantially improve safety, decision-making, and outcomes across the entire cardiac surgical continuum. Full article
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11 pages, 3617 KB  
Article
The Effect of Conventional Ho:YAG, Magneto Ho:YAG and Thulium Fiber Laser on Soft Tissue: An Ex Vivo Comparative Study in Porcine Kidney
by Theodoros Spinos, Dimitra Gkanetsou, Vasileios Tatanis, Angelis Peteinaris, Michail Papapanou, Moisés Rodríguez Socarrás, Fernando Gómez Sancha, Athanasios Vagionis, Georgios-Eleftherios Anagnostopoulos, Evangelos Liatsikos and Panagiotis Kallidonis
J. Clin. Med. 2026, 15(3), 1074; https://doi.org/10.3390/jcm15031074 - 29 Jan 2026
Viewed by 345
Abstract
Background/Objectives: In an attempt to combine the benefits of the Holmium:YAG (Ho:YAG) laser and Thulium Fiber Laser (TFL), the “Magneto” mode lowers the peak power of the Ho:YAG laser, generating longer duration pulses. The purpose of this study is to compare the [...] Read more.
Background/Objectives: In an attempt to combine the benefits of the Holmium:YAG (Ho:YAG) laser and Thulium Fiber Laser (TFL), the “Magneto” mode lowers the peak power of the Ho:YAG laser, generating longer duration pulses. The purpose of this study is to compare the effect of the standard virtual basket (VB) Ho:YAG laser, Magneto Ho:YAG laser and TFL on soft tissue in an ex vivo model. Methods: Two renal units from a female pig were used for the current experiment. Sixteen distinct areas were defined. Each area included three parallel lines, which were made with the three different laser technologies. The VB Ho:YAG laser was used for the first line and the Ho:YAG laser in the “Magneto mode” was used to generate the second line, while the third line was performed with a TFL in short pulse mode. The same laser settings (1 J/10 Hz/10 W) and the same fiber diameter (200 μm) were used for all three laser incisions. The same surgeon performed all incisions with a standardized and repeatable technique, controlling hand speed and distance of laser fiber from kidney surface using the stabilization setup. Sections of the selected areas produced distinct paraffin blocks, each one containing three parallel laser lines. Two independent pathologists evaluated the incision depth, incision width, coagulation depth and carbonization effect of the three different lasers. Results: Although the incision depth and the carbonization effect were comparable between the three lasers, incision width and coagulation depth showed a statistically significant difference. Median incision width was 1.17 (1.04, 1.99) mm for the VB Ho:YAG laser, 1.05 (0.89, 1.50) mm for the Magneto Ho:YAG laser and 0.82 (0.65, 0.88) mm for the TFL (p = 0.001). The coagulation depth was 0.49 (0.41, 0.56) mm for the VB Ho:YAG laser, 0.51 (0.39, 0.59) mm for the Magneto Ho:YAG laser and 0.18 (0.17, 0.23) mm for the TFL (p < 0.001). During post hoc analysis for the three comparisons, the differences between the VB Ho:YAG laser and TFL and between the Magneto Ho:YAG laser and TFL were statistically significant for both parameters. Conclusions: Both the VB and Magneto Ho:YAG lasers produced laser incisions with statistically significant greater incision width and coagulation depth than the TFL on the ex vivo model. Overall, the Magneto Ho:YAG laser was associated with the greatest median coagulation depth. Post Hoc Man–Whitney tests for the three comparisons revealed statistically significant differences only between the VB Ho:YAG laser and TFL and between the Magneto Ho:YAG laser and TFL. This finding could potentially be translated into better haemostasis during endourological soft tissue surgery. The implementation of additional studies, both experimental and clinical ones, is of outmost importance to draw safer conclusions. Full article
(This article belongs to the Section Nephrology & Urology)
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16 pages, 3814 KB  
Article
Advanced Digital Workflow for Lateral Orbitotomy in Orbital Dermoid Cysts: Integration of Point-of-Care Manufacturing and Intraoperative Navigation
by Gonzalo Ruiz-de-Leon, Manuel Tousidonis, Jose-Ignacio Salmeron, Ruben Perez-Mañanes, Sara Alvarez-Mokthari, Marta Benito-Anguita, Borja Gonzalez-Moure, Diego Fernandez-Acosta, Susana Gomez de los Infantes-Peña, Myriam Rodriguez-Rodriguez, Carlota Ortiz-Garcia, Ismael Nieva-Pascual, Pilar Cifuentes-Canorea, Jose-Luis Urcelay and Santiago Ochandiano
J. Clin. Med. 2026, 15(3), 937; https://doi.org/10.3390/jcm15030937 - 23 Jan 2026
Viewed by 172
Abstract
Background: Orbital dermoid cysts are common benign lesions; however, deep-seated or recurrent lesions near the orbital apex pose major surgical challenges due to their proximity to critical neurovascular structures. Lateral orbitotomy remains the reference approach, but accurate osteotomies and stable reconstruction can be [...] Read more.
Background: Orbital dermoid cysts are common benign lesions; however, deep-seated or recurrent lesions near the orbital apex pose major surgical challenges due to their proximity to critical neurovascular structures. Lateral orbitotomy remains the reference approach, but accurate osteotomies and stable reconstruction can be difficult to achieve using conventional techniques. This study reports our initial experience using a fully digital, hospital-based point-of-care (POC) workflow to enhance precision and safety in complex orbital dermoid cyst surgery. Methods: We present a case series of three patients with orbital dermoid cysts treated at a tertiary center (2024–2025) using a comprehensive digital workflow. Preoperative assessment included CT and/or MRI followed by virtual surgical planning (VSP) with orbit–tumor segmentation and 3D modeling. Cutting guides and patient-specific implants (PSIs) were manufactured in-house under a certified hospital-based POC protocol. Surgical strategies were tailored to each lesion and included piezoelectric osteotomy, intraoperative navigation, intraoperative CT, and structured-light scanning when indicated. Results: Complete en bloc resection was achieved in all cases without capsular rupture or optic nerve injury. Intraoperative CT confirmed complete lesion removal and accurate PSI positioning and fitting. Structured-light scanning enabled radiation-free postoperative monitoring when used. All patients preserved full ocular motility, visual acuity, and facial symmetry, with no complications or recurrences during follow-up. Conclusions: The integration of VSP, in-house POC manufacturing, and image-guided surgery within a lateral orbitotomy approach provides a reproducible and fully integrated workflow. This strategy appears to improve surgical precision and safety while supporting optimal long-term functional and aesthetic outcomes in challenging orbital dermoid cyst cases. Full article
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17 pages, 1344 KB  
Review
Virtual Surgical Planning (VSP) in Orthognathic Surgery for Non-Syndromic Cleft Patients: A Scoping Review of Trends and Clinical Outcomes
by Jacek Drążek, Filip Bliźniak, Karolina Lubecka, Joanna Wołoszyn, Mateusz Kęska, Maciej Chęciński, Mariusz Szuta and Maciej Sikora
J. Clin. Med. 2026, 15(2), 911; https://doi.org/10.3390/jcm15020911 - 22 Jan 2026
Viewed by 177
Abstract
Background/Objectives: Isolated cleft lips and/or palates often require orthognathic treatment. Traditional planning based on 2D images and plaster models limits precision; therefore, virtual surgical planning (VSP) and Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) technologies are increasingly being used. The aim of this scoping [...] Read more.
Background/Objectives: Isolated cleft lips and/or palates often require orthognathic treatment. Traditional planning based on 2D images and plaster models limits precision; therefore, virtual surgical planning (VSP) and Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) technologies are increasingly being used. The aim of this scoping review was to analyze the techniques, outcomes, and gaps in research on VSP in orthognathics for patients with isolated (non-syndromic) clefts. Methods: Searches were conducted in July 2025 in seven databases (including PubMed, Scopus, and Cochrane) without language restrictions, in accordance with the PRISMA guidelines for scoping reviews. Of the 2836 records, 36 publications were eligible after deduplication and full-text screening, and their Level of Evidence (LoE) was assessed using the Oxford CEBM scale. A risk of bias assessment was also conducted according to JBI tools. Results: The identified studies primarily comprised LoE III and IV; there were no systematic reviews or randomized controlled trials (LoE I). Descriptions of bimaxillary procedures and LeFort I osteotomies dominated. The most commonly used software was ProPlan CMF, Dolphin 3D, and Rhinoceros, although other tools have emerged in recent years. The available studies suggest that VSP increases translational and rotational accuracy and facilitates individualized treatment, and bimaxillary procedures bring better functional and aesthetic outcomes in patients with severe maxillary hypoplasia. Conclusions: Despite the growing interest in VSP in orthognathics, the scientific evidence is limited and mostly of lower quality. Well-designed prospective studies are needed to assess the long-term stability, quality of life, and cost-effectiveness of modern technologies. Full article
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23 pages, 10017 KB  
Article
Over a Decade of Maxillofacial PEEK Patient-Specific Innovation: A Retrospective Review of the Evolution from In-House Craft to Virtual Design and Remote Manufacturing
by Nicholas J. Lee, Gareth Honeybone, Mohammed Anabtawi, Mathew Thomas and Sachin M. Salvi
Craniomaxillofac. Trauma Reconstr. 2026, 19(1), 8; https://doi.org/10.3390/cmtr19010008 - 21 Jan 2026
Viewed by 177
Abstract
Maxillofacial skeletal reconstruction presents significant challenges due to anatomical complexity, functional requirements, and aesthetic demands. Traditional materials such as titanium and autogenous bone grafts have limitations, prompting interest in Polyetheretherketone (PEEK), a versatile thermoplastic polymer with advantages like biocompatibility, radiolucency, and elasticity similar [...] Read more.
Maxillofacial skeletal reconstruction presents significant challenges due to anatomical complexity, functional requirements, and aesthetic demands. Traditional materials such as titanium and autogenous bone grafts have limitations, prompting interest in Polyetheretherketone (PEEK), a versatile thermoplastic polymer with advantages like biocompatibility, radiolucency, and elasticity similar to human bone. This multi-year case series evaluates the clinical outcomes of PEEK implants used in 56 cases on 53 patients for maxillofacial reconstruction, primarily for trauma (44 patients) and deformity (9 patients). PEEK implants were applied to various facial regions including the orbit, zygoma, mandible, and maxilla. The majority of surgeries utilised virtual surgical planning. Patient-specific implants were fabricated using 3D imaging technologies, allowing customisation for optimal fit and functionality. The mean patient age was 37 years with a split of 37 to 16 females. Some complications were noted such as infection and paraesthesia. However, the majority of patients experienced positive outcomes. The findings support PEEK implants as a safe, effective, and adaptable material for maxillofacial surgery, with potential for further advancements in material properties and surgical technologies to improve long-term outcomes. Full article
(This article belongs to the Special Issue Innovation in Oral- and Cranio-Maxillofacial Reconstruction)
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14 pages, 1068 KB  
Systematic Review
Use of CAD/CAM Workflow and Patient-Specific Implants for Maxillary Reconstruction: A Systematic Review
by Diana D’Alpaos, Giovanni Badiali, Francesco Ceccariglia, Ali Nosrati and Achille Tarsitano
J. Clin. Med. 2026, 15(2), 647; https://doi.org/10.3390/jcm15020647 - 13 Jan 2026
Viewed by 219
Abstract
Background: Reconstruction of the maxilla and midface remains one of the most demanding challenges in craniofacial surgery, requiring precise planning and a clear understanding of defect geometry to achieve functional and esthetic restoration. Advances in computer-assisted surgery (CAS) and virtual surgical planning [...] Read more.
Background: Reconstruction of the maxilla and midface remains one of the most demanding challenges in craniofacial surgery, requiring precise planning and a clear understanding of defect geometry to achieve functional and esthetic restoration. Advances in computer-assisted surgery (CAS) and virtual surgical planning (VSP), based on 3D segmentation of radiologic imaging, have significantly improved the management of maxillary deformities, allowing for further knowledge of patient-specific information, including anatomy, pathology, surgical planning, and reconstructive issues. The integration of computer-aided design and manufacturing (CAD/CAM) and 3D printing has further transformed reconstruction through customized titanium meshes, implants, and surgical guides. Methods:This systematic review, conducted following PRISMA 2020 guidelines, synthesizes evidence from clinical studies on CAD/CAM-assisted reconstruction of maxillary and midfacial defects of congenital, acquired, or post-resection origin. It highlights the advantages and drawbacks of maxillary reconstruction with patient-specific implants (PSISs). Primary outcomes are represented by accuracy in VSP reproduction, while secondary outcomes included esthetic results, functions, and assessment of complications. Results: Of the 44 identified articles, 10 met inclusion criteria with a time frame from April 2013 to July 2022. The outcomes of 24 treated patients are reported. CAD/CAM-guided techniques seemed to improve osteotomy accuracy, flap contouring, and implant adaptation. Conclusions: Although current data support the efficacy and safety of CAD/CAM-based approaches, limitations persist, including high costs, technological dependency, and variable long-term outcome data. This article critically evaluates the role of PSISs in maxillofacial reconstruction and outlines future directions for its standardization and broader adoption in clinical practice. Full article
(This article belongs to the Special Issue Innovations in Head and Neck Surgery)
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10 pages, 2302 KB  
Article
Impact of a Virtual Three-Dimensional Thyroid Model on Patient Communication in Thyroid Surgery: A Randomized Controlled Trial
by Zhen Cao, Qiyao Zhang, Shangcheng Yan, Zhihong Qian, Xiequn Xu and Ziwen Liu
Cancers 2026, 18(2), 241; https://doi.org/10.3390/cancers18020241 - 13 Jan 2026
Viewed by 260
Abstract
Background: Effective preoperative patient counseling is essential to shared decision-making. In thyroid surgery, patient communication can be complicated by the complex anatomy and variable surgical approaches, which may not be fully conveyed through conventional verbal explanations or schematic drawings. Virtual three-dimensional (3D) thyroid [...] Read more.
Background: Effective preoperative patient counseling is essential to shared decision-making. In thyroid surgery, patient communication can be complicated by the complex anatomy and variable surgical approaches, which may not be fully conveyed through conventional verbal explanations or schematic drawings. Virtual three-dimensional (3D) thyroid models may provide an intuitive tool to enhance patient comprehension. Methods: We conducted a randomized controlled trial at Peking Union Medical College Hospital with 94 newly-diagnosed thyroid cancer patients scheduled for thyroidectomy. Participants were assigned to either the control group (n = 47), which received preoperative drawing-based counseling, or the intervention group (n = 47), which utilized a virtual 3D model for communication. The Thyroid Navigator app, developed by Kuma Hospital, was used to provide dynamic 3D representation of the thyroid gland, surrounding structures, and potential surgical procedures. After standardized preoperative consultations, patients were surveyed to assess their understanding in pertinent anatomy and postoperative complications. Results: Patients in the 3D model group demonstrated similar correct response rates in lesion localization (p = 0.536) or parathyroid gland recognition (p = 0.071), but significantly higher accuracy in identifying the recurrent laryngeal nerve and the extent of lymph node dissection compared with the control group (p < 0.05). Moreover, comprehension of the causes of major postoperative complications—including hoarseness (recurrent laryngeal nerve injury, p = 0.004), hypocalcemia (parathyroid gland impairment, p = 0.015), and bleeding (inadequate hemostasis, p = 0.008)—was significantly improved in the 3D model group. Conclusions: Use of a virtual 3D thyroid model significantly improves patient comprehension of thyroid anatomy, surgical procedures, and potential complications, thereby enhancing clinician–patient communication. Virtual 3D models represent a practical and cost-effective supplement to conventional counseling in thyroid surgery, offering clear benefits in patient education and shared decision-making. Full article
(This article belongs to the Section Methods and Technologies Development)
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33 pages, 12778 KB  
Article
From Digital Planning to Surgical Precision: Assessing the Accuracy of NemoFAB in Orthognathic Surgery
by Robert-Paul Avrămuț, Serban Talpos, Andra-Alexandra Stăncioiu, Alexandru Cătălin Motofelea, Malina Popa and Camelia-Alexandrina Szuhanek
J. Clin. Med. 2026, 15(2), 532; https://doi.org/10.3390/jcm15020532 - 9 Jan 2026
Viewed by 298
Abstract
Background/Objectives: Three-dimensional virtual surgical planning (VSP) is increasingly central to contemporary orthognathic surgery, enhancing diagnostic precision and enabling more reliable forecasts of postoperative outcomes. NemoFAB (Nemotec, Madrid, Spain) is a recently developed digital platform that integrates CBCT data, digital dental models, and [...] Read more.
Background/Objectives: Three-dimensional virtual surgical planning (VSP) is increasingly central to contemporary orthognathic surgery, enhancing diagnostic precision and enabling more reliable forecasts of postoperative outcomes. NemoFAB (Nemotec, Madrid, Spain) is a recently developed digital platform that integrates CBCT data, digital dental models, and facial photographs into a single workflow. Despite its growing clinical use, independent validation of its predictive accuracy remains limited. This study evaluated how closely NemoFAB virtual predictions corresponded to actual postoperative results using standardized cephalometric parameters. Methods: Forty adult patients with dento-maxillofacial deformities requiring combined orthodontic–surgical treatment were included. Eleven cephalometric variables—common to both WebCeph (2D) and NemoFAB (3D)—were measured preoperatively, virtually in NemoFAB, and postoperatively. AI-assisted landmark placement was manually verified by two orthodontists. Statistical analyses included repeated-measures ANOVA, paired t-tests, Bland–Altman plots, and intraclass correlation coefficients (ICC) to evaluate agreement and predictive accuracy. Results: Overjet, overbite, maxillary incisor inclination, maxillary incisor exposure, mandibular incisor projection to the True Vertical Line, and occlusal plane angulation all showed statistically significant changes after surgery (p < 0.05). Bland–Altman analysis demonstrated the narrowest limits of agreement in Nemo–Post comparisons, indicating strong predictive alignment. ICC values showed excellent agreement for incisor angulation (ICC = 0.921–0.984) and Pogonion projection (ICC = 0.943). Consistently poor pre-Nemo agreement reflected expected discrepancies between initial anatomy and planned surgical correction. Conclusions: When predicting skeletal and dentoalveolar changes brought about by orthognathic surgery, NemoFAB showed a high degree of agreement, especially for parameters that are directly impacted by jaw repositioning. Its strong concordance with postoperative outcomes supports its reliability for virtual planning, interdisciplinary coordination, and surgical execution. Advances in soft-tissue modeling and AI-driven automation may further enhance predictive accuracy. Full article
(This article belongs to the Special Issue Orthodontics: Current Advances and Future Options)
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25 pages, 10769 KB  
Review
Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization
by Majeed Rana, Andreas Sakkas, Matthias Zimmermann, Maurício Kostyuk and Guilherme Schwarz
J. Clin. Med. 2026, 15(2), 427; https://doi.org/10.3390/jcm15020427 - 6 Jan 2026
Viewed by 571
Abstract
Objective: The objective of this study is to synthesize and critically appraise how artificial intelligence (AI) is being integrated into oral and maxillofacial surgery (OMFS). This review’s novel contribution is to jointly map clinical applications (diagnostics, virtual surgical planning, intraoperative guidance) and [...] Read more.
Objective: The objective of this study is to synthesize and critically appraise how artificial intelligence (AI) is being integrated into oral and maxillofacial surgery (OMFS). This review’s novel contribution is to jointly map clinical applications (diagnostics, virtual surgical planning, intraoperative guidance) and operational uses (triage, scheduling, documentation, patient communication), quantifying evidence and validation status to provide practice-oriented guidance for adoption. Study Design: A narrative review of the recent literature and expert analysis, supplemented by illustrative multicenter implementation data from OMFS practice, was carried out. Results: AI demonstrates high performance in radiographic analysis and virtual planning (up to 96% predictive accuracy and sub-millimeter soft-tissue simulation error), with clinical reports of shorter planning times and more efficient patient communication. Early deployments in OMFS clinics have increased appointment bookings, while maintaining high patient satisfaction, and reduced the administrative burden. Remaining challenges include data quality, explainability, and limited multicenter and pediatric validation, which constrain generalizability and require clinician oversight. Conclusions: AI offers substantive benefits across the OMFS care continuum—improving diagnostic accuracy, surgical planning, and patient engagement while streamlining workflows. Responsible adoption depends on transparent validation, data governance, and targeted training, with attention to cost-effectiveness. Immediate priorities include standardized reporting of quantitative outcomes (e.g., sensitivity, specificity, time saved) and prospective multicenter studies, ensuring that AI augments—rather than replaces—human-centered care. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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