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Physiologia
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Feature Papers in Human Physiology—3rd Edition
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Feature Papers in Human Physiology—3rd Edition

A special issue of Physiologia (ISSN 2673-9488).

Deadline for manuscript submissions: 1 September 2025 | Viewed by 1589

Special Issue Editor

Prof. Dr. Philip J. Atherton

E-Mail Website
Guest Editor
School of Medicine, Royal Derby Hospital, University of Nottingham, Nottingham, UK
Interests: skeletal muscle; nutrition; metabolism; protein synthesis; ageing; cell signalling
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is designed to publish high-quality papers in Physiologia, a new journal dedicated to recent advances in the research area of physiology. The Special Issue engages with topics including, but not limited to, the following: musculoskeletal physiology, endocrine physiology, adipose physiology, and cardiovascular physiology (in health, aging, and/or disease). This Special Issue will present a collection of research articles and review articles highlighting interesting results in the field of human physiology.

Over the past two years, our first two volumes have attracted a diverse range of high-quality contributions from renowned experts and emerging scholars alike. The publications have not only showcased the latest advancements and trends in human physiology but have also fostered valuable discussions and collaborations across the global research community. These articles can be accessed through the following links:

https://www.mdpi.com/journal/physiologia/special_issues/human_physiol;

https://www.mdpi.com/journal/physiologia/special_issues/27UWS2W0PF.

Following this, we intend to annually update the Special Issue to provide scholars with the most recent and innovative perspectives on human physiology. 

Prof. Dr. Philip J. Atherton
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Physiologia is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • musculoskeletal physiology
  • endocrine physiology
  • adipose physiology
  • cardiovascular physiology (in health, aging, and/or disease)

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Related Special Issues

Published Papers (2 papers)

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10 pages, 1158 KiB  
Article
Monitoring of Salivary Secretory Immunoglobulin A Quantified Two Methods During High-Altitude Volleyball Training Camp
by Ryota Sone, Kenji Yamamoto, Shinsuke Tamai, Honoka Goji and Kenji Ohishi
Physiologia 2025, 5(1), 8; https://doi.org/10.3390/physiologia5010008 - 14 Feb 2025
Viewed by 588
Abstract
Background/Objectives: Volleyball training camps are known to reduce salivary secretory immunoglobulin A (s-SIgA); however, when it begins to decrease is unclear. The validity of a simple device for quantifying s-SIgA is lacking; hence, this study aimed to observe detailed s-SIgA changes during a [...] Read more.
Background/Objectives: Volleyball training camps are known to reduce salivary secretory immunoglobulin A (s-SIgA); however, when it begins to decrease is unclear. The validity of a simple device for quantifying s-SIgA is lacking; hence, this study aimed to observe detailed s-SIgA changes during a volleyball training camp after moving to a high altitude and to investigate the difference in s-SIgA response between the two quantification methods, namely, the enzyme-linked immunosorbent assay (ELISA) and lateral flow device (LFD). Methods: Twenty-four male university volleyball players participated in the observational study. Measurements were collected at three points of the training camp (days 1, 4, and 7). The s-SIgA was quantified using conventional ELISA and the new LFD method. Results: The s-SIgA concentrations quantified using the two methods decreased significantly by day 4 (p < 0.05) and continued to decrease until day 7 (p < 0.05). A significant positive correlation was found between the s-SIgA concentrations quantified using the LFD and ELISA (p < 0.05, rs = 0.319). Conclusions: These results indicate that a high-altitude volleyball training camp may suppress oral immune function by day 4 and that the evaluation of s-SIgA concentration using the LFD method is beneficial. A faster and easier method for assessing s-SIgA could contribute to athletes’ condition management strategies. Full article
(This article belongs to the Special Issue Feature Papers in Human Physiology—3rd Edition)
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14 pages, 833 KiB  
Article
Indexes of Fat Oxidation from Ramp vs. Graded Incremental Protocols in Postmenopausal Women
by Massimo Teso, Luca Ferrari, Alessandro L. Colosio and Silvia Pogliaghi
Physiologia 2025, 5(1), 3; https://doi.org/10.3390/physiologia5010003 - 6 Jan 2025
Viewed by 582
Abstract
The maximal rate of fat oxidation (MFO, in g∙min−1) and the relative exercise intensity at which it occurs (FATmax, as %V̇O2max) are indexes of metabolic flexibility. The time-consuming, graded exercise protocol required for MFO/FATmax determination hinders [...] Read more.
The maximal rate of fat oxidation (MFO, in g∙min−1) and the relative exercise intensity at which it occurs (FATmax, as %V̇O2max) are indexes of metabolic flexibility. The time-consuming, graded exercise protocol required for MFO/FATmax determination hinders the extensive use of these indexes for individualized exercise prescription and monitoring. Purpose: validate ramp testing for MFO and FATmax measures in postmenopausal women. Methods: Seventeen healthy women (age: 54 ± 4 years, BMI 22 ± 3 kg·m−2, and V̇O2max 36.4 ± 5.3 mL·min−1), who were 4 ± 3 years from menopause, performed on a cycle-ergometer, a ramp, and a graded incremental test. Based on V̇O2 and respiratory exchange ratio from the ramp and graded protocol (i.e., the 5th minute of each step), MFO and FATmax were determined. Data from the two protocols were compared using paired t-tests, linear regression, and Bland–Altman analysis. Results: The MFO measured with a ramp protocol was not different from (0.24 ± 0.09 vs. 0.20 ± 0.08 g·min−1, p = 0.10), and moderately associated with, that of the graded protocol (r2 = 0.46). FATmax occurred at similar exercise intensity for both protocols (47.8 ± 5.1 vs. 47.5 ± 4.3 %V̇O2max, p = 0.91, r2 = 0.52). The comparison of MFO and FATmax across the protocols yields a non-significant bias but a relatively large limit of agreement (respectively, 0.05 g·min−1, LOA = −0.08, and 0.19 g·min−1; 0.3 %V̇O2max, LOA = −7.8, and 10.6 %V̇O2max). Conclusions: In postmenopausal women, ramp testing offers a valid alternative to the graded protocol for identifying MFO and FATmax. The availability of a time- and cost-efficient approach, which can be incorporated into standard ramp incremental testing, can facilitate using these indexes of metabolic flexibility in research and medicine. Full article
(This article belongs to the Special Issue Feature Papers in Human Physiology—3rd Edition)
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