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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Photo(electro)catalysts: Design, Synthesis and Molecular Applications
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3703 | Submission Open
Keywords: catalyst; photocatalyst; photo(electro)catalyst; electrocatalyst; nanomaterials; CO2 and N2 reduction; H2; H2O2 production
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Research on Plant-Associated Nitrogen-Fixing Bacteria
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 3682 | Submission Open
Keywords: plants; microbes; rhizobia; frankia; symbiosis; chemical biology; interspecific interactions; nitrogen fixation
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research in Bacterial Vaginosis submission deadline 30 May 2024 | 2 articles | Viewed by 3498 | Submission Open
Keywords: bacterial vaginosis; biofilms; genital infections; molecular diagnostics; recurrent bacterial vaginosis; molecular research; Gardnerella vaginalis; sequencing; hybridization methods
(This special issue belongs to the Section Molecular Microbiology)
Metallo-Proteins: Structure, Function and Their Roles in Health and Disease
edited by , Luigi Russo and
submission deadline 30 May 2024 | 2 articles | Viewed by 3348 | Submission Open
Keywords: metal-binding proteins: structure; function and properties; protein folding and dynamics; metal ions exposure; uptake; toxicity; coordination complex formation; signal transduction; molecular recognition; abnormal metal-protein complex formations; environmental contaminants; mechanisms of action and effects on human health; metallo-proteins as drug targets
(This special issue belongs to the Section Molecular Biophysics)
Lung Cancers: An Update on Molecular Diagnostics and Therapy
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3336 | Submission Open
Keywords: lung cancer; cancer cachexia; prognosis; anti-lung cancer agents
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Progression of Genome-Related Diseases submission deadline 30 May 2024 | 4 articles | Viewed by 3307 | Submission Open
Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health
(This special issue belongs to the Section Molecular Genetics and Genomics)
Ion Channels in the Nervous System
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3295 | Submission Open
Keywords: voltage-gated ion channels; ligand-gated ion channels; neurons; glia cells; electrical activity; molecular structure; molecular pathway
(This special issue belongs to the Section Molecular Neurobiology)
Role of Cytokines and Their Receptors in Human Tumors and Immune-Regulation
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3263 | Submission Open
Keywords: cytokines; cytokine receptors; immune regulation; cytokine expression regulation; tumorogenesis; tumor development
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanisms of Action of Adaptogens—in Search of Natural Methods of Restoring Homeostasis
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3243 | Submission Open
Keywords: adaptogens; nutraceutical; phytotherapy; stress; homeostasis; anti-inflammatory effects; phytochemicals; anti-oxidants; oxidative stress; nutritional factors; epigenetics; herb
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Functional Polymeric Materials: From Synthesis to Applications submission deadline 30 May 2024 | 5 articles | Viewed by 3214 | Submission Open
Keywords: natural polymers; bio-based polymers; block copolymers; micelles; polymer chemistry; (hydro)gels; (bio)applications; degradability
(This special issue belongs to the Section Materials Science)
State-of-the-Art Molecular Neurobiology in Chile 2.0
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 3164 | Submission Open
Keywords: neurological disorders; neurodegeneration; pharmacology; protein structure; neuroinflammation; neurophysiology
(This special issue belongs to the Section Molecular Neurobiology)
Melatonin in Plant: From Molecular Basis to Functional Application
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3050 | Submission Open
Keywords: melatonin; phytohormone; cellular signaling; redox molecule; homeostasis; crop application; circadian ryhthm
(This special issue belongs to the Section Molecular Plant Sciences)
Viral Infections and Cancer: Recent Advances and Future Perspectives
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2859 | Submission Open
Keywords: virus; infection; cancer; immune response
(This special issue belongs to the Section Molecular Oncology)
Molecular Advances in Liver Fibrosis
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 2818 | Submission Open
Keywords: liver fibrosis; inflammation; hypoxia; angiogenesis; hepatic stellate cells; drug therapy; natural compounds; phytochemicals
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Reprogramming the Tumor Microenvironment in Pancreatic Cancer
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2783 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
Essential Metals in Neurological Diseases and Cancer
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2482 | Submission Open
Keywords: neurodegenerative disorders; cancer; essential metals; Alzheimer’ s disease; psychiatric disordes; copper; iron; zinc
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Deciphering Allergies—Structural and Immunological Characterization of Allergenic Proteins and Immunomodulatory Agents submission deadline 30 May 2024 | 3 articles | Viewed by 2381 | Submission Open
Keywords: allergen; allergenicity; IgE; innate immunity; exposome; cross-reactivity; B cell epitopes; T cell epitopes; in silico prediction
(This special issue belongs to the Section Molecular Immunology)
The Angiotensin in Human Health and Diseases
edited by Helmy M. Siragy
submission deadline 30 May 2024 | 2 articles | Viewed by 2268 | Submission Open
Keywords: renin– angiotensin– aldosterone system; angiotensin subtype receptors; cardiovascular disease; kidney diseases; stroke; metabolic abnormalities; obesity and adipose tissue; oxidative stress and inflammation; blood pressure and salt sensitivity
(This special issue belongs to the Section Molecular Biology)
Theoretical Calculations in Materials Sciences: Molecular Structure and Spectra
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2248 | Submission Open
Keywords: molecular structure; nature of chemical bonding; IR spectra; EA spectra; NMR; XRD; DFT; ab initio
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Bioactive Phenolics and Polyphenols 2024
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2183 | Submission Open
Keywords: phenolic metabolism; biological activities; stability to food processing; elicitation; methods of analysis; dietary supplements; nutraceutical ingredients; non-thermal processing; extraction and purification
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Inflammation and Neurological Diseases: Molecular Mechanisms and Therapeutic Implications
edited by Inamul Haque
submission deadline 30 May 2024 | 2 articles | Viewed by 2073 | Submission Open
Keywords: CNS; neuroinflammation; Alzheimer's disease; Parkinson's disease; multiple sclerosis; epilepsy; NLRP3 inflammasome; therapeutic; microRNA; blood– brain barrier
(This special issue belongs to the Section Molecular Neurobiology)
Recent Advances on Multi-Target Directed Ligands
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 2039 | Submission Open
Keywords: multi-target-directed ligands; drug discovery; drug design; synthesis; biological activity; polypharmacology; molecular modelling; cancer; neurodegenerative diseases; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sleep Apnea and Intermittent Hypoxia 4.0
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1984 | Submission Open
Keywords: sleep apnea syndrome; intermittent hypoxia; oxidative stress; gene expression; diabetes; appetite; obesity; hypertension
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research in Human Microbiome 2.0 submission deadline 30 May 2024 | 1 articles | Viewed by 1978 | Submission Open
Keywords: microbiome; microbial population; inflammatory bowel disease; bacterial translocation; Clostridium difficile infection
(This special issue belongs to the Section Molecular Microbiology)
Plant Pathogen Interactions 2.0 submission deadline 30 May 2024 | 3 articles | Viewed by 1947 | Submission Open
Keywords: pathogenicity; plant immunity; pattern-triggered immunity (PTI); effector-triggered immunity (ETI); effectors; avirulent; virulent; biotroph; necrotroph; interactions
(This special issue belongs to the Section Molecular Plant Sciences)
The Road to Tolerance: Molecular Biomarkers for Prediction and Diagnosis of Post-transplant Complications in Liver Transplantation
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1888 | Submission Open
Keywords: acute rejection; animal models; biliary complications; chronic rejection; cirrhosis; fatty liver; fibrosis; hepatitis; hepatocellular carcinoma; jaundice; NASH; omics; tolerance  
(This special issue belongs to the Section Molecular Immunology)
Functional Biocatalytic Molecules in Microbial Systems in Extreme Environments
edited by Isao Yumoto
submission deadline 30 May 2024 | 1 articles | Viewed by 1847 | Submission Open
Keywords: microbial ecosystem; functional molecules; extremophile; utilization of physicochemical conditions; biocatalyst
(This special issue belongs to the Section Molecular Microbiology)
Epigenomics in Cancer Research: A Comprehensive Approach submission deadline 30 May 2024 | 1 articles | Viewed by 1760 | Submission Open
Keywords: epigenomics; DNA methylation; histone post-translational markers; non-coding RNAs; 3D chromatin structure; cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sepsis: From Molecular Mechanisms, Pathophysiology to Novel Therapeutic Approaches 4.0 submission deadline 30 May 2024 | 2 articles | Viewed by 1675 | Submission Open
Keywords: sepsis; animal models; therapy concept; biomarkers; immune suppression; epigenetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Pathology and Treatment of Neuromuscular Disease
edited by Christopher Nelke and Christina B. Schroeter
submission deadline 30 May 2024 | 1 articles | Viewed by 1546 | Submission Open
Keywords: complements; myasthenia gravis; neuromuscular diseases; neuromuscular junction; hereditary disorders; amyotrophic lateral sclerosis; personalized treatments
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Studies on Tissue-Specific Endothelial Cells in Development, Homeostasis and Disease 3.0
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 1539 | Submission Open
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Targeting Blood Vessels in Cancer and Fibrosis submission deadline 30 May 2024 | 1 articles | Viewed by 1466 | Submission Open
Keywords: blood vessels; angiogenesis; fibrosis; fibroblasts; hypoxia; pericytes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Parasite Biology and Host-Parasite Interactions 2.0 submission deadline 30 May 2024 | 1 articles | Viewed by 1445 | Submission Open
Keywords: parasite; immunity; immunomodulation; helper T cells; IgA; IgE; eosinophils; mast cells; regulatory T cells; galectin
(This special issue belongs to the Section Molecular Biology)
The Role of Natural Compounds in Cancer and Inflammation
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1422 | Submission Open
Keywords: natural compounds; oxidative stress; anti-cancer; anti-inflammatory; natural product synthesis and biological activities
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research on Amyloidosis in Pathobiology and Therapy
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1357 | Submission Open
Keywords: amyloidosis; ATTR; transthyretin; misfolding; molecular mechanisms; molecular therapeutic targets; molecular imaging; SPECT; tracers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms Subserving Taste and Olfaction Systems
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 1352 | Submission Open
Keywords: taste; olfaction; gustation; odor; chemoreception; taste bud cells; nutrient sensing; ingestive behavior; olfactory cilia; olfactory receptor neurons; olfactory bulb; gustatory cortex; piriform cortex; sensory development; food learning; neural plasticity; obesity; eating disorders; appetite
(This special issue belongs to the Section Molecular Neurobiology)
Homocysteine in Protein Structure and Function and Human Disease submission deadline 30 May 2024 | 1 articles | Viewed by 1345 | Submission Open
Keywords: Alzheimer's disease; amyloid beta; autophagy; cardiovascular disease; epigenetic regulation; homocysteine thiolactone; methionyl-tRNA synthetase; mTOR signalling; protein homocysteinylation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Quantitative Identification and Action-Mechanisms of Anti-cancer and Anti-inflammatory Natural Compounds 3.0 submission deadline 30 May 2024 | 1 articles | Viewed by 1235 | Submission Open
Keywords: anticancer; anti-inflammatory; natural compounds; efficacy; mechanism of action; molecular target; bioactivity; pharmacokinetics; pharmacodynamics
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insight into Cannabinoid Effects 3.0
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 1229 | Submission Open
Keywords: cannabinoids; endogenous cannabinoids; neurodegenerative diseases; cancer; pharmacology
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Nano and Micro-Plastics in Aquatic Systems
edited by Antonio Cid-Samamed
submission deadline 30 May 2024 | 1 articles | Viewed by 1192 | Submission Open
Keywords: micro/nanoplastics (MNPs); MNPs’ characterization; MNPs’ colloidal behavior; MNPs’ sorption/desorption of other pollutants; MNPs’ aging; MNPs’ degradation
(This special issue belongs to the Section Materials Science)
Plant-Derived Bioactive Compounds during Pregnancy: Benefits and Risks
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1100 | Submission Open
Keywords: phytonutrients; dietary polyphenols; antioxidants; pregnancy; placenta; placental barrier; embryo implantation; embryo development; cell culture; animal model; clinical trial; preeclampsia; gestational diabetes mellitus; intrauterine growth restriction; advanced maternal age; transgenerational health promotion
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Redox Physiology in Biomedicine and Ecophysiology: The Influence of Various Substances on the Redox Regulation of Cell Metabolism, 2nd Edition
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1003 | Submission Open
Keywords: redox-signalling pathways; antioxidative and hypoglicemic effects of plant extracts; prooxidant/antioxidant status in the cells; redox active trace metals; reproductive health of women and men: infertility/sterility; xenobiotics in aquatic organims; essential trace elements and immunological parameters in COVID/post-COVID patients
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Research on Prostate Cancer
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 994 | Submission Open
Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Cardiac Regenerative Medicine
edited by Ken Takahashi
submission deadline 30 May 2024 | 1 articles | Viewed by 988 | Submission Open
Keywords: heart failure; human induced pluripotent stem cells; hiPSCs; 3D bioprinting; regenerative medicine; tissue engineering
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Viral Hepatitis and Liver Cancer
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 976 | Submission Open
Keywords: hepatitis B; hepatitis C; hepatitis D; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The 150th Anniversary of the Discovery of L.A. Ranvier: Specialization and Plasticity of Fiber Types in the Vertebrate Skeletal Muscles submission deadline 30 May 2024 | 1 articles | Viewed by 951 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Research on Molecular Dynamics 2.0
edited by and
submission deadline 30 May 2024 | 1 articles | Viewed by 906 | Submission Open
Keywords: molecular dynamics; quantum mechanics/molecular mechanics approaches; conformational change; dynamic changes of intermolecular interactions; protein– ligand interactions; nucleic acid ligand interactions; computational modeling of molecular systems; drug design and delivery; structure– function relationships in proteins; simulation of drug-like molecules and lipid membranes
(This special issue belongs to the Section Molecular Biophysics)
Molecular Research in Chemical Mixtures Toxicology
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 887 | Submission Open
Keywords: mixtures toxicity; pulmonary toxicity; inhalation lung; screening; biocide; emulsifier; household products; spray
(This special issue belongs to the Section Molecular Toxicology)
Advances on Retinal Diseases 2.0
edited by Minzhong Yu
submission deadline 30 May 2024 | 1 articles | Viewed by 859 | Submission Open
Keywords: retina; optic nerve; ocular disorder; retinal disease; genetic mutation; aging; drug side effects; novel mutations/biomarkers; signaling pathways; spectral domain optical coherence tomography; stem cell; gene therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular and Molecular Studies of Dopamine and Its Receptors
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 786 | Submission Open
Keywords: neuroscience; dopamine; dopamine receptors; peripheral immunity
(This special issue belongs to the Section Molecular Biology)
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