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Advances and Future Trends in Mass Spectrometry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 538

Special Issue Editors


E-Mail Website
Guest Editor
Department of Applied Chemistry, Environmental Protection and Occupational Safety and Health Center, National Chi Nan University, Puli, Nantou, Taiwan
Interests: physical chemistry; mass spectrometry
SCIEX, 71 Four Valley Drive, Concord, ON L4K 4V8, Canada
Interests: mass spectrometry; sample preparation; high-throughput analysis; drug discovery; bioanalysis
Merck Research Laboratories, Rahway, NJ, USA
Interests: mass spectrometry; biomolecular imaging; instrumentation development; machine learning; pharmaceutical development

Special Issue Information

Dear Colleagues,

In recent decades, mass spectrometry has become a fundamental tool for understanding the characteristics of chemical species. Rapid advances in mass spectrometry techniques enable both qualitative and quantitative analyses of proteins, polymers, metabolites, lipids, drugs, etc., from highly complex reactions and chemical biological samples. This has led to broad and unique applications of mass spectrometry to a variety of scientific fields, including synthetic chemistry, pharmaceutical discovery and development, and chemical biological research.

In this Special Issue, entitled “Advances and Future Trends in Mass Spectrometry”, we would like to present current technical developments in the fields of compound analysis, spatial and single-cell mass spectrometry, high-throughput mass spectrometry, and a variety of novel mass spectrometry applications in chemical drug design and therapy, energy and environmental analysis. We warmly welcome researchers to contribute to this Special Issue in the form of research articles, reviews and communications.

Prof. Dr. Chihche Wu
Dr. Chang Liu
Dr. Hang Hu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • protein analysis
  • spatial and single-cell mass spectrometry
  • high-throughput mass spectrometry
  • quantitative analyses
  • environmental analysis

Published Papers (1 paper)

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Research

13 pages, 2526 KiB  
Communication
Application of Magnetic Materials Combined with Echo® Mass Spectrometry System in Analysis of Illegal Drugs in Sewage
by Feiyu Yang, Kaijun Ma, Yichao Cao and Zhiyuan Li
Molecules 2024, 29(9), 2060; https://doi.org/10.3390/molecules29092060 - 29 Apr 2024
Viewed by 313
Abstract
The aim of this study is to solve the problems of the complicated pretreatment and high analytical cost in the detection technology of trace drugs and their metabolites in municipal wastewater. A high-performance magnetic sorbent was fsynthesized for the enrichment of trace drugs [...] Read more.
The aim of this study is to solve the problems of the complicated pretreatment and high analytical cost in the detection technology of trace drugs and their metabolites in municipal wastewater. A high-performance magnetic sorbent was fsynthesized for the enrichment of trace drugs and their metabolites in wastewater to develop a magnetic solid-phase extraction pretreatment combined with the acoustic ejection mass spectrometry (AEMS) analytical method. The magnetic nanospheres were successfully prepared by magnetic nanoparticles modified with divinylbenzene and vinylpyrrolidone. The results showed that the linear dynamic range of 17 drugs was 1–500 ng/mL, the recovery was 44–100%, the matrix effect was more than 51%, the quantification limit was 1–2 ng/mL, and the MS measurement was fast. It can be seen that the developed magnetic solid-phase extraction (MSPE) method is a good solution to the problems of the complicated pretreatment and analytical cost in the analysis of drugs in wastewater. The developed magnetic material and acoustic excitation pretreatment coupled with mass spectrometry analysis method can realize the low-cost, efficient enrichment, and fast analysis of different kinds of drug molecules in urban sewage. Full article
(This article belongs to the Special Issue Advances and Future Trends in Mass Spectrometry)
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