Next Article in Journal
Evaluation of the Biological Activity of Naturally Occurring 5,8-Dihydroxycoumarin
Previous Article in Journal
Preparation, Purification and Regioselective Functionalization of Protoescigenin—The Main Aglycone of Escin Complex
Molecules 2013, 18(4), 4403-4418; doi:10.3390/molecules18044403
Article

Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides

,  and *
State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, the Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
* Author to whom correspondence should be addressed.
Received: 5 March 2013 / Revised: 21 March 2013 / Accepted: 21 March 2013 / Published: 15 April 2013
View Full-Text   |   Download PDF [254 KB, uploaded 18 June 2014]   |   Browse Figures
SciFeed

Abstract

A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.
Keywords: C–H bond; oxidation; palladium C–H bond; oxidation; palladium
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Sit, W.-N.; Chan, C.-W.; Yu, W.-Y. Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides. Molecules 2013, 18, 4403-4418.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert